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Mechanical interactive micro interface device with the single cell through the focus desmosome.

Research Project

Project/Area Number 25630094
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Intelligent mechanics/Mechanical systems
Research InstitutionYamaguchi University

Principal Investigator

MINAMI Kazuyuki  山口大学, 創成科学研究科, 教授 (00229759)

Co-Investigator(Kenkyū-buntansha) 佐藤 克也  徳島大学, 大学院理工学研究部, 講師 (10403651)
中島 雄太  山口大学, 理工学研究科, 助教 (70574341)
中原 佐  山口大学, 創成科学研究科, 助教 (00756968)
Project Period (FY) 2013-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywordsバイオメカニクス / バイオMEMS / 微小構造体 / マイクロマシニング
Outline of Final Research Achievements

In order to clarify the feasibility of the micro device which can give a cell extension stimulation and can measure the traction force of the cell, the fabrication process of the cell extension device having the silicone chamber embedding arranged beads as a micro marker was devised, and the fabrication processes were developed for trial manufacture. In the beads arrangement process, the validity of the surface treatment methods of beads and substrate are identified, and it succeeded in some beads arrangement. However, it was seen that the establishment of the process to surely break off the cohesion of beads was necessary. In addition, the fabrication process of silicone chamber that embedded the arranged beads was developed, and it was confirmed that the fabrication of the silicone chamber that embedded beads was possible.

Report

(5 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (2 results)

All 2016 2015

All Presentation (2 results)

  • [Presentation] 細胞牽引力測定のための微小マーカー付細胞培養マイクロチャンバーの試作2016

    • Author(s)
      福岡 諒、中原 佐、南 和幸
    • Organizer
      日本機械学会中国四国支部第55期総会・講演会
    • Place of Presentation
      愛媛大学(愛媛県松山市)
    • Year and Date
      2016-03-09
    • Related Report
      2015 Research-status Report
  • [Presentation] 細胞牽引力の測定のためのシリコーン製マイクロチャンバーの開発2015

    • Author(s)
      宮崎裕考、佐藤克也、中島雄太、南 和幸
    • Organizer
      日本機械学会中国四国支部第53期総会・講演会
    • Place of Presentation
      近畿大学工学部(東広島市)
    • Year and Date
      2015-03-06
    • Related Report
      2014 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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