Development of fundamental technology to create E. coli carrying human-type glycosylation
| Project/Area Number |
25630378
|
|---|
| Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Biofunction/Bioprocess
|
|---|
| Research Institution | Osaka University |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
OHASHI Takao 大阪大学, 生物工学国際交流センター, 助教 (10597876)
|
|---|
| Project Period (FY) |
2013-04-01 – 2015-03-31
|
| Project Status |
Completed (Fiscal Year 2014)
|
| Budget Amount *help |
¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
|
|---|
| Keywords | 大腸菌 / ヒト型化 / 糖鎖 / 組換え / ヒト型糖鎖 / 組み換えタンパク質 |
|---|
| Outline of Final Research Achievements |
We developed a fundamental E. coli strain for recombinant production of glycoprotein. Further improvement of this technology would enable E. coli to produce pharamaceutical glycoproteins, such as antibody.
|
Report
(3 results)
Research Products
(4 results)
