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A study on identifying unknown cause/factor of sudden infant death

Research Project

Project/Area Number 25670343
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Legal medicine
Research InstitutionOkayama University

Principal Investigator

MIYAISHI Satoru  岡山大学, 医歯(薬)学総合研究科, 教授 (90239343)

Co-Investigator(Kenkyū-buntansha) KITAO TAKASHI  愛媛県立医療技術大学, 保健科学部, 准教授 (60218047)
TAKATA TOMOYO  愛媛県立医療技術大学, 保健科学部, 講師 (70310894)
MIURA MASANOBU  岡山大学, 大学院医歯薬学総合研究科, 助教 (80616235)
TANIGUCHI KAORI  岡山大学, 大学院医歯薬学総合研究科, 非常勤研究員 (40599784)
YAMASAKI YUKIE  岡山大学, 大学院医歯薬学総合研究科, 非常勤研究員 (60444676)
Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords乳幼児突然死 / 乳幼児突然
Outline of Final Research Achievements

Unknown factors or diseases that were not recognized to cause sudden infant death were investigated. It was thought that infection of Cronobacter sakazaki as cause of sudden death could be simply diagnosed only by the growth of that pathogen in the culture. Fulminant type Ⅰ diabetes could also be diagnosed by the extreme low level of blood 1,5-AG concentration, whereas evaluation of stress as the factor of sudden death should be examined further using saliva chromogranin A concentration.
According to the investigation of the ratios of area of the left ventricle to those of the right ventricle and the total left heart in the heart cross-section, it was suggested that the the left heart dysfunction could be another possible unknown factor/cause of infantile sudden death.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (18 results)

All 2016 2015 2014 Other

All Journal Article (5 results) (of which Peer Reviewed: 5 results,  Open Access: 1 results,  Acknowledgement Compliant: 1 results) Presentation (13 results) (of which Int'l Joint Research: 3 results,  Invited: 1 results)

  • [Journal Article] Measurement of postmortem 1,5-anhydroglucitol in vitreous humor for forensic diagnosis.2016

    • Author(s)
      Takata T, Yamasaki Y, Kitao T, Miyaishi S
    • Journal Title

      J Forensic Sci.

      Volume: Vol.61 Issue: S1

    • DOI

      10.1111/1556-4029.12963

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Sudden infant death due to Lactococcal infective endocarditis.2016

    • Author(s)
      Taniguchi K, Nakayama M, Nakahira K, Nakura Y, Kanagawa N, Yanagihara I, Miyaishi S
    • Journal Title

      Legal Medicine

      Volume: Vol.19 Pages: 107-111

    • DOI

      10.1016/j.legalmed.2015.07.013

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Child deaths with persistent neglect experiences from Medico-legal documents in Japan2015

    • Author(s)
      Yamaoka Y, Tamiya N, Fujiwara T, Yamasaki Y, Matsuzawa A, Miyaishi S
    • Journal Title

      Pediatrics International

      Volume: 57(3) Issue: 3 Pages: 1-8

    • DOI

      10.1111/ped.12531

    • Related Report
      2015 Annual Research Report 2014 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Measurement of postmortem 1,5-anhydroglucitol in vitreous humor for forensic diagnosis2015

    • Author(s)
      Takata T, Yamasaki Y, Kitao T, Miyaishi S
    • Journal Title

      J Forensic Sci

      Volume: 60

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] 死後の血漿および脳脊髄液の1,5-アンヒドログルシトール値による糖尿病の法医 診断における有用性.2014

    • Author(s)
      髙田智世、山﨑雪恵、北尾孝司、宮石智
    • Journal Title

      学検査

      Volume: 63 Pages: 680-686

    • NAID

      130005057062

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Presentation] Postmortale Diagnose des fulminanten Typ 1 Diabetes mellitus -eine Kasuistik2016

    • Author(s)
      Miyaishi S, Takata T, Taniguchi K, Miura M, Kitao T, Pueschel K.
    • Organizer
      95. Jahrestagung der Deutschen Gesellschaft fuer Rechtsmedizin
    • Place of Presentation
      Heidelberg, Germany
    • Year and Date
      2016-08-30
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 乳幼児突然死の法医解剖2016

    • Author(s)
      宮石智
    • Organizer
      第22回日本SIDS・乳幼児突然死予防学会
    • Place of Presentation
      横浜市
    • Year and Date
      2016-03-04
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 生後39日乳児突然死の1例2016

    • Author(s)
      谷口香,宮石智
    • Organizer
      第22回日本SIDS・乳幼児突然死予防学会例検討委員会
    • Place of Presentation
      横浜市
    • Year and Date
      2016-03-04
    • Related Report
      2015 Annual Research Report
  • [Presentation] Usefulness of postmortem 1,5-anhydroglucitol analysis in forensic diagnosis.2015

    • Author(s)
      Takata T, Yamasaki Y, Kitao T, Miyaishi S
    • Organizer
      第32回日本法医学会学術中四国地方集会
    • Place of Presentation
      岡山市
    • Year and Date
      2015-10-30
    • Related Report
      2015 Annual Research Report
  • [Presentation] Usefulness of postmortem 1,5-anhydroglucitol analysis in forensic diagnosis.2015

    • Author(s)
      Miyaishi S, Takata T, Yamasaki Y, Kitao T
    • Organizer
      94te Jahrestagung der Deutschen Geselschaft fuer Rechtsmedizin
    • Place of Presentation
      Leipzig,(Germany)
    • Year and Date
      2015-09-15
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] A case of sudden infant death with Cornelia de Lange syndrome2015

    • Author(s)
      Miyaishi S, Taniguchi K
    • Organizer
      23te Fruehjahrstagung der Deutschen Geselschft fuer Rechtsmedizin -Region Nord
    • Place of Presentation
      Koeln, Germany
    • Year and Date
      2015-05-08 – 2015-05-09
    • Related Report
      2014 Research-status Report
  • [Presentation] A case of sudden infant death with Cornelia de Lange syndrome.2015

    • Author(s)
      Miyaish S, Taniguchi K
    • Organizer
      24.Fruehjahrstagung der Deutschen Gesellschaft luer Rechtsmedizin. 2015.
    • Place of Presentation
      Koeln( Germany)
    • Year and Date
      2015-05-08
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Cornelia de Lange症候群の突然死の一剖検例2015

    • Author(s)
      宮石智,谷口香
    • Organizer
      第21回日本SIDS・乳幼児突然死予防学会学術集会
    • Place of Presentation
      松本
    • Year and Date
      2015-03-06 – 2015-03-07
    • Related Report
      2014 Research-status Report
  • [Presentation] Characteristics of the case of fatal child neglect - the usefulness of forensic documents2014

    • Author(s)
      Miyaishi S, Yamaoka Y, Yamasaki Y, Taniguchi K, Fujiwara T, Tamiya N
    • Organizer
      93te Jahrestagung der Deutschen Geselschaft fuer Rechtsmedizin
    • Place of Presentation
      Heringsdorf, Germany
    • Year and Date
      2014-09-09 – 2014-09-13
    • Related Report
      2014 Research-status Report
  • [Presentation] 継続的にネグレクトの経過が認められた死亡事例5例の法医公衆衛生学的考察2014

    • Author(s)
      山岡結衣,田宮菜奈子,藤原武男,山崎雪恵,谷口香,宮石智
    • Organizer
      第6回日本子ども虐待医学研究会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2014-07-12 – 2014-07-13
    • Related Report
      2014 Research-status Report
  • [Presentation] 法医学における乳幼児死亡統計の検討2014

    • Author(s)
      宮石智,山﨑雪恵,谷口香
    • Organizer
      第98次日本法医学会全国学術集会
    • Place of Presentation
      福岡
    • Year and Date
      2014-06-16 – 2014-06-20
    • Related Report
      2014 Research-status Report
  • [Presentation] 全逆位のあった9か月男児突然死の1例.

    • Author(s)
      谷口香,山崎雪恵,宮石智:
    • Organizer
      第20回日本SIDS・乳幼児突然死予防学会症例検討委員会
    • Place of Presentation
      大宮
    • Related Report
      2013 Research-status Report
  • [Presentation] ヒブワクチン・小児用肺炎球菌ワクチン同時接種翌日に突然死した生後2か月早産児の1例.

    • Author(s)
      谷口香,山崎雪恵,宮石智:
    • Organizer
      第20回日本SIDS・乳幼児突然死予防学会
    • Place of Presentation
      大宮
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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