Influence on lipid metabolism through non-image forming effect by blue LED light stimulation

• Project/Area Number: 25870478
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Applied health science; Biomedical engineering/Biomaterial science and engineering
• Research Institution: The University of Tokushima
• Principal Investigator: NAKAGAWA Tadahiko 徳島大学, ヘルスバイオサイエンス研究部, 学術研究員 (40634275)
• Project Period (FY): 2013-04-01 – 2015-03-31
• Project Status: Completed (Fiscal Year 2014)
• Budget Amount: ¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000); Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000); Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
• Keywords: 非視覚的作用 / LED光 / 脂質代謝

Outline of Final Research Achievements

Light stimulation from the eye promotes the secretion of brain hormones and corticosteroids through the endogenous light-sensitive retinal nerve cells. Thus the illumination light in daily life affects the lipid metabolism. It is considered likely to be involved in the onset or exacerbation of dyslipidemia. In this study, the results of evaluation using a mouse for changes in the brain hormone and lipid metabolism enzyme produced by the LED light is a new illumination sources increasingly widespread, was suggested effect on the lipid metabolism.