Pulse glucometry: Pioneering research towards practical non-invasive optical measurement of blood glucose
Project/Area Number |
26242044
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Research Category |
Grant-in-Aid for Scientific Research (A)
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Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Biomedical engineering/Biomaterial science and engineering
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Research Institution | Showa University |
Principal Investigator |
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Co-Investigator(Kenkyū-buntansha) |
加藤 祐次 北海道大学, 情報科学研究科, 助教 (50261582)
山越 健弘 福岡工業大学, 情報工学部, 准教授 (70444205)
李 知炯 福岡工業大学, 情報工学部, 助教 (10735583)
清水 孝一 北海道大学, 情報科学研究科, 教授 (30125322)
|
Project Period (FY) |
2014-04-01 – 2018-03-31
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Project Status |
Completed (Fiscal Year 2017)
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Budget Amount *help |
¥43,290,000 (Direct Cost: ¥33,300,000、Indirect Cost: ¥9,990,000)
Fiscal Year 2017: ¥11,440,000 (Direct Cost: ¥8,800,000、Indirect Cost: ¥2,640,000)
Fiscal Year 2016: ¥12,090,000 (Direct Cost: ¥9,300,000、Indirect Cost: ¥2,790,000)
Fiscal Year 2015: ¥9,620,000 (Direct Cost: ¥7,400,000、Indirect Cost: ¥2,220,000)
Fiscal Year 2014: ¥10,140,000 (Direct Cost: ¥7,800,000、Indirect Cost: ¥2,340,000)
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Keywords | 糖尿病 / 非侵襲光学的血糖計測 / パルス・グルコメトリ / グルコース吸収波長帯域 / 積分球式光電容積信号検出法 / 側方入射型光電容積信号検出法 / 光散乱現象 / 偏光変調型光電容積信号検出法 / グルコース吸光波長帯域 / 側方散乱光電容積脈波検出 / 組織内順直進光検出 / 生体光情報計測 / 側方散乱光電容積信号検出法 / 多波長レーザー光電容積信号計測システム / 生体光計測 / 近赤外生体センシング / レーザー計測システム / 多変量校正法 / 生体情報計測 |
Outline of Final Research Achievements |
According to a statement issued by International Diabetes Federation, diabetes population in 2015 runs up to 415 million people and Japan has diabetes powers ranked 9th in the world. In a diabetic patient blood glucose (BGL) measurement, most desirably non-invasive method without blood sampling, is needed to control BGL level. Unfortunately such practical non-invasive method has not yet been developed up to now. We have previously developed a novel non-invasive BGL measurement using a finger called “pulse glucometry” and evaluated its validity on an experimental basis. To realize technical practicability of this method, it is essential to develop a new finger-photoplethysmography (PPG) in a wavelength region with BGL absorption having quite high accuracy and sensitivity as well as convenient use. The present study was carried out focusing especially on this PPG development, aiming a basic establishment towards the world’s first non-invasive BGL measurement device for practical use.
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Report
(5 results)
Research Products
(14 results)