Functional division and interaction among prefrontal cortical areas
Project/Area Number |
26250011
|
Research Category |
Grant-in-Aid for Scientific Research (A)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Neurophysiology / General neuroscience
|
Research Institution | Institute of Physical and Chemical Research |
Principal Investigator |
Tanaka Keiji 国立研究開発法人理化学研究所, 脳科学総合研究センター, チームリーダー (00221391)
|
Co-Investigator(Renkei-kenkyūsha) |
HIGO TAKAYASU 国立研究開発法人理化学研究所, 脳科学総合研究センター, 研究員 (10396757)
|
Project Period (FY) |
2014-04-01 – 2017-03-31
|
Project Status |
Completed (Fiscal Year 2016)
|
Budget Amount *help |
¥39,780,000 (Direct Cost: ¥30,600,000、Indirect Cost: ¥9,180,000)
Fiscal Year 2016: ¥12,870,000 (Direct Cost: ¥9,900,000、Indirect Cost: ¥2,970,000)
Fiscal Year 2015: ¥12,870,000 (Direct Cost: ¥9,900,000、Indirect Cost: ¥2,970,000)
Fiscal Year 2014: ¥14,040,000 (Direct Cost: ¥10,800,000、Indirect Cost: ¥3,240,000)
|
Keywords | 認知制御 / 執行機能 / ウィスコンシンカード分類課題 / 前帯状溝皮質 / 主溝皮質 / 尾状核 / 前頭前野 / 領野間相互作用 / 尾状核頭部 / 同期活動 / 機能分化 / 投射特異的機能ブロック / 目的指向的行動 / 領野間相互佐用 |
Outline of Final Research Achievements |
To uncover the functional interaction between prefrontal cortical areas, we have conducted simultaneous local-field-potential recordings from the monkeys performing a cognitively demanding task with frequent rule switches. We have also developed a projection-specific functional blockage method with virus vectors. In the recording experiments, the anterior cingulate sulcus area, principal sulcus area, and caudate head increased the power of activities in low-beta frequency band (~15Hz) at the initial fixation period of each trial and at the inter-trial interval, and these activities in the three regions were synchronized. The transient increase of the synchronized activities suggests that the three regions exchanged signals specifically in these time epochs.
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Report
(4 results)
Research Products
(13 results)