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A study on ethical, legal and social issues of stem cell medicine

Research Project

Project/Area Number 26253032
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Research Field Medical sociology
Research InstitutionKyoto University

Principal Investigator

Fujita Misao  京都大学, iPS細胞研究所, 特定准教授 (50396701)

Co-Investigator(Kenkyū-buntansha) 前田 正一  慶應義塾大学, 健康マネジメント研究科(藤沢), 教授 (20396708)
Co-Investigator(Renkei-kenkyūsha) KODAMA Satoshi  京都大学, 大学院・文学研究科, 准教授 (80372366)
Research Collaborator HATTA Taichi  京都大学, iPS細胞研究所・上廣倫理研究部門, 特定研究員 (40598596)
SAWAI Tsutomu  京都大学, iPS細胞研究所・上廣倫理研究部門, 特定研究員 (50769817)
KASHIHARA Hidenori  広島大学, 学長室, リサーチアドミニストレーター
NAKAGAWA Chigusa  京都大学, iPS細胞研究所・上廣倫理研究部門, 特定研究員
MURATA Maho  慶応義塾大学, 健康マネジメント研究科, 特定研究員 (00444604)
KAWABE Kenichiro  慶応義塾大学, 健康マネジメント研究科, 特定研究員
Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥40,300,000 (Direct Cost: ¥31,000,000、Indirect Cost: ¥9,300,000)
Fiscal Year 2016: ¥12,740,000 (Direct Cost: ¥9,800,000、Indirect Cost: ¥2,940,000)
Fiscal Year 2015: ¥13,910,000 (Direct Cost: ¥10,700,000、Indirect Cost: ¥3,210,000)
Fiscal Year 2014: ¥13,650,000 (Direct Cost: ¥10,500,000、Indirect Cost: ¥3,150,000)
Keywords幹細胞 / iPS細胞 / 再生医療 / 生命倫理学 / 質問紙調査 / 生命倫理 / 調査 / 自由診療 / 再生医療等安全性確保法 / 研究倫理学 / 研究倫理
Outline of Final Research Achievements

(1) Issues associated with the Act on the Safety of Regenerative Medicine: official websites of clinics that provided medical treatment at one's own expense were analyzed and 74 clinics with 247 such treatments were identified; it was found that there were many treatments that had deviated from the international guidelines as well as that there were inappropriate websites with regard to advertisement regulations. (2) A survey on the general public's and researchers' attitudes: a questionnaire was administered to 520 citizens and 105 iPS cell researchers, and it was found that 60% of the general public and 80% of the researchers answered affirmatively to the question on the creation of human-pig chimeras. (3) A survey on the ethical support structure of stem cell research: a hearing was conducted on both office clerks responsible for the ethical screening and researchers in bioethics in three colleges in the US, and it was found that the separation of their roles was relatively clear.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Annual Research Report
  • 2014 Annual Research Report
  • Research Products

    (30 results)

All 2017 2016 2015 2014 Other

All Journal Article (11 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 10 results,  Acknowledgement Compliant: 3 results,  Open Access: 4 results) Presentation (17 results) (of which Int'l Joint Research: 7 results,  Invited: 2 results) Book (1 results) Remarks (1 results)

  • [Journal Article] Public attitudes in Japan towards human-animal chimeric embryo research using human induced pluripotent stem cells2017

    • Author(s)
      Sawai T, Hatta T, Fujita M
    • Journal Title

      Regenerative Medicine

      Volume: 印刷中 Issue: 3 Pages: 233-248

    • DOI

      10.2217/rme-2016-0171

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] <Articles>Moral Complicity of Human IPS Cell Research: Implications for Human IPS Cell Research in Japan2016

    • Author(s)
      澤井努
    • Journal Title

      いのちの未来

      Volume: 1 Pages: 4-33

    • DOI

      10.14989/203155

    • NAID

      120005694179

    • ISSN
      2423-9445
    • Year and Date
      2016-01-15
    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Evaluating the quality of website information on private-practice clinics offering cell therapies in Japan2016

    • Author(s)
      Kashihara H, Nakayama T, Hatta T, Takahashi N, Fujita M
    • Journal Title

      interactive Journal of Medical Research

      Volume: 5 Issue: 2 Pages: e15-e15

    • DOI

      10.2196/ijmr.5479

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] The current status of clinics providing private practice cell therapy in Japan. Regenerative Medicine2016

    • Author(s)
      Fujita M, Hatta T, Reina O, Akabayashi A
    • Journal Title

      Regenerative Medicine

      Volume: 11(1) Issue: 1 Pages: 23-32

    • DOI

      10.2217/rme.15.64

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Recent Court Ruling in Japan Exemplifies Another Layer of Regulation for Regenerative Therapy2015

    • Author(s)
      Tsunakuni Ikka, Misao Fujita, Yoshimi Yashiro, Hiroshi Ikegaya,
    • Journal Title

      Cell Stem Cell

      Volume: 17(5) Issue: 5 Pages: 507-508

    • DOI

      10.1016/j.stem.2015.10.008

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] “Mottainai” embryos and the earthquake2015

    • Author(s)
      Takahashi S, Fujita M, Akabayashi A
    • Journal Title

      Journal of Clinical Research and Bioethics

      Volume: 7 Issue: 01 Pages: 258-258

    • DOI

      10.4172/2155-9627.1000258

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 再生医療を実施する自由診療クリニックに対する民事訴訟2015

    • Author(s)
      一家綱邦、八代嘉美、藤田みさお、池谷博
    • Journal Title

      日本医事新報

      Volume: 4766 Pages: 14-16

    • Related Report
      2015 Annual Research Report
  • [Journal Article] Risk of Tumorigenesis and Patient Hope2015

    • Author(s)
      Fujita M, Hatta T, Sawai T, Takahashi J
    • Journal Title

      American Journal of Bioethics Neuroscience

      Volume: 6(1) Issue: 1 Pages: 69-70

    • DOI

      10.1080/21507740.2014.991851

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Throwing the baby out with the bathwater: a critique of Sparrow’s inclusive definition of the term ‘in vitro eugenics’2014

    • Author(s)
      Fujita M, Yashiro Y, Suzuki M
    • Journal Title

      Journal of Medical Ethics

      Volume: 40(11) Issue: 11 Pages: 735-736

    • DOI

      10.1136/medethics-2013-101681

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The moral value of induced pluripotent stem cells: A Japanese bioethics perspective on human embryo research2014

    • Author(s)
      Sawai T
    • Journal Title

      Journal of Medical Ethics

      Volume: 40(11) Issue: 11 Pages: 766-769

    • DOI

      10.1136/medethics-2013-101838

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 包括同意の諸要件とその倫理的背景―同意取得のあり方に関する一考察―2014

    • Author(s)
      及川正範,藤田みさお,赤林朗
    • Journal Title

      生命倫理

      Volume: 25 Pages: 235-243

    • NAID

      110009959794

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Presentation] 細胞治療を提供する自由診療クリニックのWebサイト:探索的調査結果と規制の動向2017

    • Author(s)
      八田太一
    • Organizer
      第16回日本再生医療学会総会
    • Place of Presentation
      仙台国際センター. 仙台
    • Year and Date
      2017-03-07
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] Public and researcher attitudes towards human-animal chimeric embryo research using human induced pluripotent stem cells2016

    • Author(s)
      Sawai T, Hatta T, Fujita M
    • Organizer
      13th World Congress of the International Association of Bioethics
    • Place of Presentation
      Edinburgh, Scotland, UK
    • Year and Date
      2016-07-17
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Untested cell therapies offered “legitimately” in Japan2016

    • Author(s)
      Fujita M, Hatta T
    • Organizer
      13th World Congress of the International Association of Bioethics
    • Place of Presentation
      Edinburgh, Scotland, UK
    • Year and Date
      2016-07-15
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Acceptability of human-animal chimeric embryo research using human induced pluripotent stem cells: a survey among the public and researchers2016

    • Author(s)
      Sawai T, Hatta T, Fujita M
    • Organizer
      ISSCR 2016 Annual Meeting
    • Place of Presentation
      San Francisco, CA, USA
    • Year and Date
      2016-06-24
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Humanized animals harboring human brain neurons and germ cells: a survey among the public and researchers2016

    • Author(s)
      Hatta T, Sawai T, Fujita M
    • Organizer
      ISSCR 2016 Annual Meeting
    • Place of Presentation
      San Francisco, CA, USA
    • Year and Date
      2016-06-22
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 日本で提供されている幹細胞治療の特徴-海外のウェブサイト調査との比較-2016

    • Author(s)
      八田太一
    • Organizer
      第15回日本再生医療学会総会
    • Place of Presentation
      大阪国際会議場、大阪
    • Year and Date
      2016-03-17
    • Related Report
      2015 Annual Research Report
  • [Presentation] ソーシャルメディアを用いたiPS・再生医療に関する話題調査2016

    • Author(s)
      若宮 翔子、八田 太一、藤田 みさお、荒牧 英治
    • Organizer
      第8回データ工学と情報マネジメントに関するフォーラム(第14回日本データベース学会年次大会)
    • Place of Presentation
      ヒルトン福岡シーホーク、福岡
    • Year and Date
      2016-03-01
    • Related Report
      2015 Annual Research Report
  • [Presentation] 包括同意の諸要件とその倫理的背景:同意取得のあり方に関する一考察2015

    • Author(s)
      及川 正範、藤田 みさお、赤林 朗
    • Organizer
      第27回日本生命倫理学会年次大会
    • Place of Presentation
      千葉大学いのはなキャンパス、千葉
    • Year and Date
      2015-11-29
    • Related Report
      2015 Annual Research Report
  • [Presentation] 日本における自由診療下での細胞治療の実態と再生医療等安全性確保法2015

    • Author(s)
      藤田みさお
    • Organizer
      第27回日本生命倫理学会年次大会
    • Place of Presentation
      千葉大学いのはなキャンパス、千葉
    • Year and Date
      2015-11-28
    • Related Report
      2015 Annual Research Report
  • [Presentation] 国内自由診療下で提供されている幹細胞治療の特徴-海外との比較-2015

    • Author(s)
      八田太一
    • Organizer
      第27回日本生命倫理学会年次大会
    • Place of Presentation
      千葉大学いのはなキャンパス、千葉
    • Year and Date
      2015-11-28
    • Related Report
      2015 Annual Research Report
  • [Presentation] 自由診療で細胞治療を提供する日本のクリニックのWebサイト情報:患者・家族の目にする医療情報の現状2015

    • Author(s)
      柏原英則、中山健夫
    • Organizer
      第27回日本生命倫理学会年次大会
    • Place of Presentation
      千葉大学いのはなキャンパス、千葉
    • Year and Date
      2015-11-28
    • Related Report
      2015 Annual Research Report
  • [Presentation] The ethics of research on stem cell derived gametes: A Japanese bioethical perspective2015

    • Author(s)
      Sawai T, Akatsuka K, Sullivan LS
    • Organizer
      17th ASBH Annual Meeting
    • Place of Presentation
      Houston, TX, USA
    • Year and Date
      2015-10-22
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The state of Japanese clinics that offer untested cell therapies2015

    • Author(s)
      Fujita M, Hatta T
    • Organizer
      17th ASBH Annual Meeting
    • Place of Presentation
      Houston, TX, USA
    • Year and Date
      2015-10-22
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Website information quality of private clinics offering unapproved regenerative therapy/stem cell therapy in Japan2015

    • Author(s)
      Kashihara H, Nakayama T, Hatta T, Fujita M
    • Organizer
      17th ASBH Annual Meeting
    • Place of Presentation
      Houston, TX, USA
    • Year and Date
      2015-10-22
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] ヒトiPS細胞研究における倫理的問題―宗教的な視座から―2015

    • Author(s)
      澤井努
    • Organizer
      日本宗教学会.第74回学術大会
    • Place of Presentation
      創価大学、東京
    • Year and Date
      2015-09-06
    • Related Report
      2015 Annual Research Report
  • [Presentation] iPS細胞研究をはじめとする再生医療の倫理的課題2015

    • Author(s)
      藤田みさお
    • Organizer
      第29回日本医学会総会2015
    • Place of Presentation
      国立京都国際会館、京都
    • Year and Date
      2015-04-11
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 再生医療新法の対象となる細胞治療とリスク分類:自由診療クリニックWebの調査より2015

    • Author(s)
      八田太一、藤田みさお
    • Organizer
      日本臨床試験学会第6回学術集会総会
    • Place of Presentation
      日本教育会館一ツ橋ホール 東京
    • Year and Date
      2015-02-20
    • Related Report
      2014 Annual Research Report
  • [Book] Uehiro Carnegie Oxford Conference 2014“ETHICS FOR THE FUTURE OF iPS / STEM CELLS2016

    • Author(s)
      Julian Savulescu and Misao Fujita (eds.)
    • Total Pages
      380
    • Publisher
      The Uehiro Foundation on Ethics and Education
    • Related Report
      2015 Annual Research Report
  • [Remarks] 京都大学iPS細胞研究所上廣倫理研究部門

    • URL

      http://www.cira.kyoto-u.ac.jp/uehiro-ethics/

    • Related Report
      2016 Annual Research Report 2015 Annual Research Report 2014 Annual Research Report

URL: 

Published: 2014-04-04   Modified: 2018-03-22  

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