| Project/Area Number |
26280097
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Intelligent robotics
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| Research Institution | Tokyo Institute of Technology |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
尾上 弘晃 慶應義塾大学, 理工学部(矢上), 准教授 (30548681)
原 雄介 国立研究開発法人産業技術総合研究所, 材料・化学領域, 研究グループ長 (90452135)
森田 雅宗 国立研究開発法人産業技術総合研究所, 生命工学領域, 研究員 (90708504)
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| Co-Investigator(Renkei-kenkyūsha) |
NAGAI Ken 北陸先端科学技術大学院大学, 先端科学技術研究科, 助教 (40518932)
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| Project Period (FY) |
2014-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥16,250,000 (Direct Cost: ¥12,500,000、Indirect Cost: ¥3,750,000)
Fiscal Year 2016: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2015: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2014: ¥7,280,000 (Direct Cost: ¥5,600,000、Indirect Cost: ¥1,680,000)
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| Keywords | 分子ロボット / 人工細胞 / DNAナノテクノロジー / マイクロマシン / 非平衡 / 自己組織化 / ゲル / エマルション / 動的自己組織化 / DNA |
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| Outline of Final Research Achievements |
In this study, we constructed methods to produce and control dynamical cell-sized molecular robots by the control of micrometer-scale nonequilibrium fields and spatiotemporal assembly of molecules. As a result of this study, we developed methods to produce asymmetric complex-shaped gel microparticles and a method to dynamically assemble the microparticles. We achieved autonomous motions of the asymmetric complex-shaped gel microparticles using chemical reaction energy. Additionally, we succeeded in biological functions of the asymmetric complex-shaped gel microparticles for cell-sized molecular robots using living cells and DNA molecules. Finally, we achieved the control of collective motions of microparticles using nonequilibrium electrical conditions. Through this study, we developed the basic technologies for the construction and control of dynamical cell-sized molecular robots.
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