Molecular structure mechanism of caveolae membrane coats
Project/Area Number |
26286027
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Research Category |
Grant-in-Aid for Scientific Research (B)
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Allocation Type | Partial Multi-year Fund |
Section | 一般 |
Research Field |
Nanobioscience
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Research Institution | Kyoto University |
Principal Investigator |
MORONE NOBUHIRO 京都大学, 物質-細胞統合システム拠点, 教授 (50399680)
|
Project Period (FY) |
2014-04-01 – 2017-03-31
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Project Status |
Completed (Fiscal Year 2016)
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Budget Amount *help |
¥15,730,000 (Direct Cost: ¥12,100,000、Indirect Cost: ¥3,630,000)
Fiscal Year 2016: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2014: ¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
|
Keywords | 1分子科学 / 細胞膜 / カベオラ / エンドサイトーシス / 1分子科学 |
Outline of Final Research Achievements |
Cavoelae are striated membrane invagination (around 70nm in diameter) at the plasma membrane except for neurons, which involved in endocytosis, transcytosis, and fatty acid uptake. Freeze-replica electron microscopy would be useful for caveolar analysis due to their fine structures on the cytoplasmic surface of plasma membrane. This research focused caveolar base structures by electron microscopy.
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Report
(4 results)
Research Products
(26 results)
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[Journal Article] Hybrid Cellular Metabolism Coordinated by Zic3 and Esrrb Synergistically Enhances Induction of Naive Pluripotency2017
Author(s)
Sone M, Morone N, Nakamura T, Tanaka A, Okita K, Woltjen K, Nakagawa M, Heuser J, Yamada Y, Yamanaka S, Yamamoto T.
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Journal Title
Cell Metabolism
Volume: 印刷中
Issue: 5
Pages: 1103-1117.e6
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
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[Journal Article] Confined diffusion of transmembrane proteins and lipids induced by the same actin meshwork lining the plasma membrane2016
Author(s)
T. K. Fujiwara, Iwasawa, K., Kalay, Z., Tsunoyama, T. A. Y. Watanabe, Y. M. Umemura, H. Murakoshi, K. G. N. Suzuki, Y. L., Nemoto, N. Morone, A. Kusumi
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Journal Title
Mol. Cell Biol.
Volume: 27
Issue: 7
Pages: 1101-1119
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
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[Journal Article] Confined diffusion of transmembrane proteins and lipids induced by the same actin meshwork lining the plasma membrane.2016
Author(s)
Fujiwara TK, Iwasawa K, Kalay Z, Tsunoyama TA, Watanabe Y, Umemura YM, Murakoshi H, Suzuki KG, Nemoto YL, Morone N, Kusumi A.
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Journal Title
Mol Biol Cell
Volume: 27
Pages: 1101-19
Related Report
Peer Reviewed / Int'l Joint Research
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[Journal Article] Regulation of cargo-selective endocytosis by dynamin 2 GTPase-activating protein girdin.2014
Author(s)
Liang Weng, Atsushi Enomoto, Hiroshi Miyoshi, Kiyofumi Takahashi, Naoya Asai, Nobuhiro Morone, Ping Jiang, Jian An, Takuya Kato, Keisuke Kuroda, Takashi Watanabe, Masato Asai, Maki Ishida-Takagishi, Yoshiki Murakumo, Hideki Nakashima, Kozo Kaibuchi and Masahide Takahashi.
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Journal Title
EMBO Journal.
Volume: 33
Issue: 18
Pages: 2098-2112
DOI
Related Report
Peer Reviewed / Open Access
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[Journal Article] Mesoscopic Metal Nanoparticles Doubly Functionalized with natural and engineered lipidic dispersants for therapeutics2014
Author(s)
Murakami, T., Nakatsuji, H., Morone, N., Heuser, J. E., Ishidate, F., Hashida, M., Imahori, H.
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Journal Title
ACS Nano
Volume: 8
Issue: 7
Pages: 7370-7376
DOI
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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