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Synthetic Study of Biologically Active Natural Products Based on the Novel Chiral Pool Approach

Research Project

Project/Area Number 26288018
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypePartial Multi-year Fund
Section一般
Research Field Organic chemistry
Research InstitutionKeio University

Principal Investigator

CHIDA Noritaka  慶應義塾大学, 理工学部(矢上), 教授 (50197612)

Project Period (FY) 2014-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥16,640,000 (Direct Cost: ¥12,800,000、Indirect Cost: ¥3,840,000)
Fiscal Year 2017: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2016: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2015: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2014: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Keywords天然物合成 / キラルプール法 / タキソール / ネオステニン / カイトセファリン / 有機合成化学 / ステニン / パクリタキセル / 全合成
Outline of Final Research Achievements

The chiral pool approach is a highly effective and reliable method for the synthesis of biologically active natural products in optically pure form. In this project, synthetic studies toward taxol (diterpenoids possessing anticancer activity), neostenine (alkaloid with antitussive activity), and kaitocephalin (amino acid with antagonistic activity of glutamate receptor), based on the chiral pool approach utilizing carbohydrate as starting material, were carried out. The successful syntheses of these natural products revealed the effectiveness of the chiral pool methodology and brought about the progress of the methodology.

Report

(5 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Annual Research Report
  • 2015 Annual Research Report
  • 2014 Annual Research Report
  • Research Products

    (60 results)

All 2018 2017 2016 2015 2014 Other

All Journal Article (19 results) (of which Int'l Joint Research: 8 results,  Peer Reviewed: 19 results,  Open Access: 5 results,  Acknowledgement Compliant: 1 results) Presentation (37 results) (of which Int'l Joint Research: 2 results,  Invited: 11 results) Book (2 results) Remarks (2 results)

  • [Journal Article] Synthesis of β-Hydroxy-α,α-disubstituted Amino Acids through the Orthoamide-Type Overman Rearrangement of an α,β-Unsaturated Ester and Stereodivergent Intramolecular SN2’ Reaction: Development and Application to the Total Synthesis of Sphingofungin F2018

    • Author(s)
      Sugai Tomoya、Usui Shunme、Tsuzaki Shun、Oishi Hiroki、Yasushima Daichi、Hisada Shoko、Fukuyasu Takahiro、Oishi Takeshi、Sato Takaaki、Chida Noritaka
    • Journal Title

      Bulletin of the Chemical Society of Japan

      Volume: 91 Issue: 4 Pages: 594-607

    • DOI

      10.1246/bcsj.20170408

    • NAID

      130006707638

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Synthesis of Kaitocephalin Facilitated by Three Stereoselective Allylic Transposition Reactions2018

    • Author(s)
      Sugai Tomoya、Okuyama Yuya、Shin Jaehyun、Usui Shunme、Hisada Shoko、Osanai Ryosuke、Oishi Takeshi、Sato Takaaki、Chida Noritaka
    • Journal Title

      Chemistry Letters

      Volume: 47 Issue: 4 Pages: 454-457

    • DOI

      10.1246/cl.171226

    • NAID

      130006638880

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Unified Total Synthesis of Madangamines A, C, and E2017

    • Author(s)
      Suto, T.; Yanagita, Y.; Nagashima, Y.; Takikawa, S.; Kurosu, Y.; Matsuo, N.; Sato T.; Chida, N.
    • Journal Title

      Journal of the American Chemical Society

      Volume: 139 Issue: 8 Pages: 2952-2955

    • DOI

      10.1021/jacs.7b00807

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Reductive Approach to Nitrones from <i>N</i>-Siloxyamides and <i>N</i>-Hydroxyamides2017

    • Author(s)
      Katahara Seiya、Kobayashi Shoichiro、Fujita Kanami、Matsumoto Tsutomu、Sato Takaaki、Chida Noritaka
    • Journal Title

      Bulletin of the Chemical Society of Japan

      Volume: 90 Issue: 8 Pages: 893-904

    • DOI

      10.1246/bcsj.20170086

    • NAID

      130005973688

    • ISSN
      0009-2673, 1348-0634
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Unified Total Synthesis of Stemoamide-Type Alkaloids by Chemoselective Assembly of Five-Membered Building Blocks2017

    • Author(s)
      Yoritate Makoto、Takahashi Yoshito、Tajima Hayato、Ogihara Chisato、Yokoyama Takashi、Soda Yasuki、Oishi Takeshi、Sato Takaaki、Chida Noritaka
    • Journal Title

      Journal of the American Chemical Society

      Volume: 139 Issue: 50 Pages: 18386-18391

    • DOI

      10.1021/jacs.7b10944

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Practical Synthesis of the C-ring Precursor of Paclitaxel from 3-Methoxytoluene2016

    • Author(s)
      Fukaya, K.; Yamaguchi, Y.; Watanabe, A.; Yamamoto, H.; Sugai, S.; Sugai, T.; Sato T.; *Chida, N.
    • Journal Title

      The Journal of Antibiotics

      Volume: 69 Issue: 4 Pages: 273-279

    • DOI

      10.1038/ja.2016.6

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] An Iridium-Catalyzed Reductive Approach to Nitrones from N-Hydroxyamides2016

    • Author(s)
      S. Katahara, S. Kobayashi, K. Fujita, T. Matsumoto, T. Sato, N. Chida
    • Journal Title

      Journal of the American Chemical Society

      Volume: 138 Issue: 16 Pages: 5246-5249

    • DOI

      10.1021/jacs.6b02324

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Total Synthesis of (-)-Stemoamide by Sequential Overman/Claisen Rearrangement2016

    • Author(s)
      Nakayama, M.; Maeda, Y.; Hama, N.; *Sato T.; *Chida, N.
    • Journal Title

      Synthesis

      Volume: 48 Issue: 11 Pages: 1647-1654

    • DOI

      10.1055/s-0035-1561948

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Copper-Catalyzed Electrophilic Amination Using N-Methoxyamines2016

    • Author(s)
      Fukami, Y.; Wada, T.; Meguro, T.; Chida, N.; *Sato, T.
    • Journal Title

      Organic & Biomolecular Chemistry

      Volume: 14 Issue: 24 Pages: 5486-5489

    • DOI

      10.1039/c5ob02167g

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] N-アルコキシアミド基への求核付加反応の開発とゲフィロトキシンの全合成2016

    • Author(s)
      佐藤隆章,千田憲孝
    • Journal Title

      有機合成化学協会誌

      Volume: 74 Pages: 599-610

    • NAID

      130005164586

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Enantioselective Total Synthesis of (+)-Neostenine2016

    • Author(s)
      Nakayama, M.; Maeda, Y.; Kotatsu, M.; Sekiya, R.; Ichiki, M.; *Sato, T.; *Chida, N.
    • Journal Title

      Chemisty A European Journal

      Volume: 22 Issue: 10 Pages: 3300-3303

    • DOI

      10.1002/chem.201600058

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Crystal structure of (+/-)-(1SR,5SR,6SR,7SR,10SR,11SR,13SR)-14-benzoyloxy-7-methodymethoxy-11,15,18,18-tetramethyl-3-oxo-2,4-dioxatetracyclo[12.3.1.0.0]octadeca-14,16-dien-10-yl benzoate2015

    • Author(s)
      T. Oishi, K. Fukaya, Y. Yamaguchi, T. Sugai, A. Watanabe, T. Sato and N. Chida
    • Journal Title

      Acta Crystallographica Section E

      Volume: 71 Issue: 5 Pages: 490-493

    • DOI

      10.1107/s2056989015007136

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Synthesis of Paclitaxel. 1. Synthesis of the ABC-Ring of Paclitaxel by SmI2-Mediated Cyclization2015

    • Author(s)
      Fukaya, K.; Tanaka, Y.; Sato, A.; Kodama, K.; Yamazaki, H.; Ishimoto, T.; Nozaki, Y.; Iwaki, Y.; Yuki, Y.; Umei, K.; Sugai, T.; Yamaguchi, Y.; Watanabe, A.; Oishi, T.; Sato, T.; *Chida, N.
    • Journal Title

      Organic Letters

      Volume: 17 Issue: 11 Pages: 2570-2573

    • DOI

      10.1021/acs.orglett.5b01173

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Synthesis of Paclitaxel. 2. Construction of the ABCD-Ring and Formal Synthesis2015

    • Author(s)
      Fukaya, K.; Kodama, K.; Tanaka, Y.; Yamazaki, H.; Sugai, T.; Yamaguchi, Y.; Watanabe, A.; Oishi, T.; *Sato, T.; *Chida, N.
    • Journal Title

      Organic Letters

      Volume: 17 Issue: 11 Pages: 2574-2577

    • DOI

      10.1021/acs.orglett.5b01174

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Crystal structure of (+/-)-(7RS,8SR)-7-methyl-1,4-dioxaspiro[4.5]decane-7,8-diol2015

    • Author(s)
      T. Oishi, H. Yamamoto, T. Sugai, K. Fukaya, Y. Yamaguchi, A. Watanabe, T. Sato and N. Chida
    • Journal Title

      Acta Crystallographica Section E

      Volume: 71 Issue: 10 Pages: 1181-1184

    • DOI

      10.1107/s2056989015016783

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Total Synthesis of Sphingofungin F by Orthoamide-Type Overman Rearrangement of an Unsaturated Ester2015

    • Author(s)
      Tsuzaki, S.; Usui, S.; Oishi, H.; Yasushima, D.; Fukuyasu, T.; Oishi, T.; Sato T.; Chida, N.
    • Journal Title

      Org. Lett.

      Volume: 17 Issue: 7 Pages: 1704-1707

    • DOI

      10.1021/acs.orglett.5b00475

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Crystal structure of (+/-)-(4RS,5RS,7SR)-4-[(1RS,2RS,3RS,6RS)-3-benzoyloxy-2-(2-hydroxyethyl)-6-methoxymethoxy-2-methylcyclohexyl]-8,10,10-trimethyl-2-oxo-1,3-dioxaspiro[4.5]dec-8-en-7-yl benzoate benzene monosolvate2015

    • Author(s)
      T. Oishi, Y. Yamaguchi, K. Fukaya, T. Sugai, A. Watanabe, T. Sato, and N. Chida
    • Journal Title

      Acta Crystallographica Section E

      Volume: 71 Issue: 1 Pages: 8-11

    • DOI

      10.1107/s2056989014026048

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Crystal structures of (±)-(1SR,5SR,6SR,7SR,10SR,11SR,13RS,14SR)-13-hydroxy-7-methoxymethoxy-11,15,18,18-tetramethyl-3-oxo-2,4-dioxatetracyclo[12.3.1.0-1,5.0-6,11]octadec-15-en-10-yl benzoate, its 13-epimer and 13-one derivative2015

    • Author(s)
      T. Oishi, K. Fukaya, Y. Yamaguchi, T. Sugai, A. Watanabe, T. Sato, and N. Chida
    • Journal Title

      Acta Crystallographica Section E

      Volume: 71 Issue: 5 Pages: 466-472

    • DOI

      10.1107/s2056989015006854

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Synthesis of Natural Products Containing Cyclohexane Units Utilizing the Ferrier Carbocyclization Reaction2014

    • Author(s)
      N. Chida and T. Sato
    • Journal Title

      Chemical Record

      Volume: 14 Issue: 4 Pages: 592-605

    • DOI

      10.1002/tcr.201402024

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Presentation] 生物活性天然物の全合成:キラルプール法によるアプローチ2018

    • Author(s)
      千田憲孝
    • Organizer
      日本化学会第98春季年会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] パクリタキセルの改良合成2018

    • Author(s)
      山本 拓央,深谷 圭介,山口 友,渡部 愛海,望月 翔太,斎尾 諒祐,佐藤 隆章,千田 憲孝
    • Organizer
      日本化学会第98春季年会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 連続的Overman転位を鍵反応とした(+)-Saxitoxin の合成研究2018

    • Author(s)
      奥山優也,岡本凌輔,佐藤隆章,千田憲孝
    • Organizer
      日本化学会第98春季年会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Unified Total Synthesis of Stemoamide-type Alkaloids Featuring Chemoselective Assembly of Five-membered Building Blocks2018

    • Author(s)
      Yoritate Makoto, Takahashi Yoshito, Tajima Hayato, Ogihara Chisato, Soda Yasuki, Yokoyama Takashi, Oishi Takeshi, Sato Takaaki, Chida Noritaka
    • Organizer
      日本化学会第98春季年会
    • Related Report
      2017 Annual Research Report
  • [Presentation] イリジウム触媒を用いた二級アミド基の還元的求核付加反応2018

    • Author(s)
      高橋 芳人,吉井 梨紗,佐藤 隆章,千田 憲孝
    • Organizer
      日本化学会第98春季年会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Reductive Approach to Nitrones from N-Siloxyamides and N-Hydroxyamides2018

    • Author(s)
      Katahara Seiya, Fujita Kanami, Kobayashi Shoichiro, Matsumoto Tsutomu, Sato Takaaki, Chida Noritaka
    • Organizer
      日本化学会第98春季年会
    • Related Report
      2017 Annual Research Report
  • [Presentation] (-)-ゼフィランチンの全合成2017

    • Author(s)
      石井孝樹,石橋瑞基,関結菜,佐藤隆章,千田憲孝
    • Organizer
      日本化学会第97春季年会
    • Place of Presentation
      慶應義塾大学日吉キャンパス(横浜市港北区)
    • Year and Date
      2017-03-16
    • Related Report
      2016 Annual Research Report
  • [Presentation] (-)-Stenineの全合成2017

    • Author(s)
      小辰将之,中山泰彰,前田悠一郎,佐藤隆章,千田憲孝
    • Organizer
      日本化学会第97春季年会
    • Place of Presentation
      慶應義塾大学日吉キャンパス(横浜市港北区)
    • Year and Date
      2017-03-16
    • Related Report
      2016 Annual Research Report
  • [Presentation] Overman転位を用いた(-)-Kaitocephalinの合成研究2017

    • Author(s)
      須貝智也,奥山優也,臼井駿馬,久田祥子,申在賢,佐藤隆章,千田憲孝
    • Organizer
      日本化学会第97春季年会
    • Place of Presentation
      慶應義塾大学日吉キャンパス(横浜市港北区)
    • Year and Date
      2017-03-16
    • Related Report
      2016 Annual Research Report
  • [Presentation] タキソールの改良合成研究2017

    • Author(s)
      渡部愛海,深谷圭介,山本拓央,佐藤隆章,千田憲孝
    • Organizer
      日本化学会第97春季年会
    • Place of Presentation
      慶應義塾大学日吉キャンパス(横浜市港北区)
    • Year and Date
      2017-03-16
    • Related Report
      2016 Annual Research Report
  • [Presentation] 不飽和エステルのOverman転位の開発と(-)-カイトセファリンへの応用2017

    • Author(s)
      須貝智也,臼井駿馬,奥山優也,久田祥子,申在賢,大石宙輝,佐藤隆章,千田憲孝
    • Organizer
      第111回有機合成シンポジウム
    • Related Report
      2017 Annual Research Report
  • [Presentation] タキソールの合成研究2017

    • Author(s)
      千田憲孝
    • Organizer
      第29回万有札幌シンポジウム
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] パクリタキセルの改良合成研究2017

    • Author(s)
      山本拓央,深谷圭介,山口友,渡辺愛海,望月翔太,佐藤隆章,千田憲孝
    • Organizer
      第61回香料・テルペンおよび精油化学に関する討論会
    • Related Report
      2017 Annual Research Report
  • [Presentation] ステモアミド系アルカロイドの網羅的全合成2017

    • Author(s)
      佐藤隆章,寄立真琴,高橋芳人,田島隼人,荻原知里,横山貴,千田憲孝
    • Organizer
      第59回天然有機化合物討論会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 生物活性天然物の合成研究:キラルプール法によるアプローチ2017

    • Author(s)
      千田憲孝
    • Organizer
      有機合成化学協会関東支部ミニシンポジウム多摩2017
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 生物活性天然物の合成研究ーキラルプール法によるアプローチ2016

    • Author(s)
      千田憲孝
    • Organizer
      京都大学大学院薬学研究科特別講演会
    • Place of Presentation
      京都大学薬学部(京都市)
    • Year and Date
      2016-07-06
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] 生物活性天然物の合成研究ーキラルプール法によるアプローチ2016

    • Author(s)
      千田憲孝
    • Organizer
      有機合成セミナー(有機合成化学協会東海支部)
    • Place of Presentation
      静岡県立大学(静岡県静岡市)
    • Year and Date
      2016-06-11
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] タキソールの合成研究2016

    • Author(s)
      千田憲孝
    • Organizer
      第71回有機合成化学協会関東支部シンポジウム
    • Place of Presentation
      東京農工大学小金井キャンパス(東京都小金井市)
    • Year and Date
      2016-05-14
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] (-)-カイトセファリンの合成研究2016

    • Author(s)
      須貝智也,臼井駿馬,奥山優也,久田祥子,佐藤隆章,千田憲孝
    • Organizer
      第71回有機合成化学協会関東支部シンポジウム
    • Place of Presentation
      東京農工大学小金井キャンパス(東京都小金井市)
    • Year and Date
      2016-05-14
    • Related Report
      2016 Annual Research Report
  • [Presentation] タキソールの合成研究2016

    • Author(s)
      千田憲孝
    • Organizer
      有機化学研究会第76回講演会(白鷺セミナー)
    • Place of Presentation
      大阪府立大学(大阪府堺市)
    • Year and Date
      2016-04-08
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] タキソールの改良合成研究2016

    • Author(s)
      深谷圭介,山口友,渡辺愛海,山本拓央,須貝智也,佐藤隆章,千田憲孝
    • Organizer
      日本化学会第96春季年会
    • Place of Presentation
      同志社大学京田辺キャンパス(京都府京田辺市)
    • Year and Date
      2016-03-24
    • Related Report
      2015 Annual Research Report
  • [Presentation] (-)-Kaitocephalinの合成研究2016

    • Author(s)
      須貝智也,臼井駿馬,久田祥子,奥山優也,佐藤隆章,千田憲孝
    • Organizer
      日本化学会第96春季年会
    • Place of Presentation
      同志社大学京田辺キャンパス(京都府京田辺市)
    • Year and Date
      2016-03-24
    • Related Report
      2015 Annual Research Report
  • [Presentation] The Sequential Overman/Claisen Rearrangement: Development and Application to Total Synthesis of (+)-Neostenine2016

    • Author(s)
      Y. Nakayama, Y. Maeda, M. Kotatsu, R. Sekiya, M. Ichiki, T. Sato, and N. Chida
    • Organizer
      日本化学会第96春季年会
    • Place of Presentation
      同志社大学京田辺キャンパス(京都府京田辺市)
    • Year and Date
      2016-03-24
    • Related Report
      2015 Annual Research Report
  • [Presentation] Sequential Sigmatropic Rearrangement: Development and Its Application to the Synthesis of Natural Product2016

    • Author(s)
      N. Chida
    • Organizer
      The 3rd Mini-Symposium on Cutting-Edge Chemistry
    • Place of Presentation
      National Tsing Hua University (Hsinchu, Taiwan)
    • Year and Date
      2016-03-11
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] バイオマス利用キラルプール法による生物活性天然物の合成2015

    • Author(s)
      千田憲孝
    • Organizer
      平成27年度後期有機合成化学講習会
    • Place of Presentation
      日本薬学会長井記念ホール(東京都・渋谷区)
    • Year and Date
      2015-11-16
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] Synthesis of Taxol2015

    • Author(s)
      K. Fukaya, T. Sugai, H. Yamazaki, K. Kodama, T. Sato, and N. Chida
    • Organizer
      The 13th International Conference on New Aspects of Organic Chemistry
    • Place of Presentation
      Rihga Royal Hotel Kyoto (Kyoto, Japan)
    • Year and Date
      2015-11-09
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 連続的Overman/Claisen転位の開発と(+)-ネオステニン全合成2015

    • Author(s)
      中山泰彰,前田悠一郎,小辰将之,関谷瑠璃子,市來政人,佐藤隆章,千田憲孝
    • Organizer
      第57回天然有機化合物討論会
    • Place of Presentation
      神奈川県民ホール(横浜市)
    • Year and Date
      2015-09-09
    • Related Report
      2015 Annual Research Report
  • [Presentation] 糖質利用キラルプール法による天然物の合成研究2015

    • Author(s)
      千田憲孝
    • Organizer
      平成27年度第34回日本糖質学会
    • Place of Presentation
      東京大学(東京都・文京区)
    • Year and Date
      2015-07-31
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] スフィンゴファンジンFの全合成:不飽和エステルを用いたOverman転位の開発と応用2015

    • Author(s)
      佐藤隆章,津崎俊,臼井駿馬,大石宙輝,安嶋大智,福安崇宏,大石毅,千田憲孝
    • Organizer
      第107回有機合成シンポジウム
    • Place of Presentation
      慶應義塾大学薬学部(東京都・港区)
    • Year and Date
      2015-06-09
    • Related Report
      2015 Annual Research Report
  • [Presentation] リコリン類の合成研究2015

    • Author(s)
      関結菜、石橋瑞基、佐藤隆章、千田憲孝
    • Organizer
      日本化学会第95春季年会
    • Place of Presentation
      日本大学理工学部船橋キャンパス(千葉県・船橋市)
    • Year and Date
      2015-03-26 – 2015-03-29
    • Related Report
      2014 Annual Research Report
  • [Presentation] オルトアミド型Overman転位とSN2'反応を用いた1,2-アミノアルコール合成法の開発2015

    • Author(s)
      安嶋大智、津崎俊、大石宙輝、佐藤隆章、千田憲孝
    • Organizer
      日本化学会第95春季年会
    • Place of Presentation
      日本大学理工学部船橋キャンパス(千葉県・船橋市)
    • Year and Date
      2015-03-26 – 2015-03-29
    • Related Report
      2014 Annual Research Report
  • [Presentation] (-)-Kaitocephalinの合成研究2015

    • Author(s)
      臼井駿馬、須貝智也、佐藤隆章、千田憲孝
    • Organizer
      日本化学会第95春季年会
    • Place of Presentation
      日本大学理工学部船橋キャンパス(千葉県・船橋市)
    • Year and Date
      2015-03-26 – 2015-03-29
    • Related Report
      2014 Annual Research Report
  • [Presentation] Synthesis of Taxol2015

    • Author(s)
      K. Fukaya, T. Sugai, H. Yamazaki, K. Kodama, Y. Yamaguchi, T. Sato, and N. Chida
    • Organizer
      日本化学会第95春季年会
    • Place of Presentation
      日本大学理工学部船橋キャンパス(千葉県・船橋市)
    • Year and Date
      2015-03-26 – 2015-03-29
    • Related Report
      2014 Annual Research Report
  • [Presentation] タキソールの合成2014

    • Author(s)
      深谷圭介、須貝智也、山崎裕久、小玉圭祐、山口友、佐藤隆章、千田憲孝
    • Organizer
      第56回天然有機化合物討論会
    • Place of Presentation
      高知県立県民文化ホール(高知県・高知市)
    • Year and Date
      2014-10-15 – 2014-10-17
    • Related Report
      2014 Annual Research Report
  • [Presentation] タキソールの合成研究2014

    • Author(s)
      山口友、深谷圭介、須貝智也、須貝威、佐藤隆章、千田憲孝
    • Organizer
      第58回香料・テルペンおよび精油化学に関する討論会
    • Place of Presentation
      和歌山大学(和歌山県・和歌山市)
    • Year and Date
      2014-09-20 – 2014-09-22
    • Related Report
      2014 Annual Research Report
  • [Presentation] 連続的Overman/Claisen転位の開発と(-)-Stemoamideの全合成2014

    • Author(s)
      中山泰彰、前田悠一郎、関谷瑠璃子、佐藤隆章、千田憲孝
    • Organizer
      第44回複素環化学討論会
    • Place of Presentation
      札幌市民ホール(北海道・札幌市)
    • Year and Date
      2014-09-10 – 2014-09-12
    • Related Report
      2014 Annual Research Report
  • [Presentation] キラルプール法による生物活性天然物の合成研究2014

    • Author(s)
      千田憲孝
    • Organizer
      平成26年度若手研究者のためのセミナー
    • Place of Presentation
      岐阜薬科大学(岐阜県・岐阜市)
    • Year and Date
      2014-08-05
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Book] アルカロイドの科学2017

    • Author(s)
      高山 廣光(編),千田 憲孝(分担執筆)
    • Total Pages
      560
    • Publisher
      化学同人
    • ISBN
      9784759814187
    • Related Report
      2017 Annual Research Report
  • [Book] Molecular Rearrangements in Organic Synthesis2015

    • Author(s)
      Noritaka Chida
    • Publisher
      John Wiley & Sons
    • Related Report
      2015 Annual Research Report
  • [Remarks] 慶應義塾大学理工学部応用化学科千田・佐藤研究室ホームページ

    • URL

      http://www.applc.keio.ac.jp/~chida/

    • Related Report
      2017 Annual Research Report
  • [Remarks] 慶應義塾大学理工学部応用化学科千田研究室ホームページ

    • URL

      http://www.applc.keio.ac.jp/~chida/

    • Related Report
      2016 Annual Research Report 2015 Annual Research Report 2014 Annual Research Report

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Published: 2014-04-04   Modified: 2019-03-29  

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