Application of hydrogen absorption/release characteristics of sulfur-poisoning nanoparticles to cancer detection
| Project/Area Number |
26289255
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Partial Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Structural/Functional materials
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| Research Institution | Nagoya University |
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Principal Investigator |
Yagi Shinya 名古屋大学, 未来材料・システム研究所, 教授 (20284226)
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| Co-Investigator(Kenkyū-buntansha) |
吉田 朋子 名古屋大学, エコトピア科学研究所, 准教授 (90283415)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥16,120,000 (Direct Cost: ¥12,400,000、Indirect Cost: ¥3,720,000)
Fiscal Year 2016: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2015: ¥5,980,000 (Direct Cost: ¥4,600,000、Indirect Cost: ¥1,380,000)
Fiscal Year 2014: ¥8,060,000 (Direct Cost: ¥6,200,000、Indirect Cost: ¥1,860,000)
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| Keywords | ナノ粒子 / 水素吸放出 / ガン検知 / 硫黄被毒 / Rhナノ粒子 / 酸素被毒 / Pdナノ粒子 / XPS測定 / ガス中蒸発法 / 生体・医療・福祉材料 / がんスクリーニング / XAFS分析 / 金ナノ粒子 / 硫黄分子吸着 / XAFS測定 |
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| Outline of Final Research Achievements |
We have fabricated the nanoparticles of Rh and Pd by gas evaporation method. The particle sizes of both Rh and Pd are estimated to be approximately 1-4 nm. Although a sulfur-containing molecules (mainly thiol-based molecules) adsorbed on the Rh nanoparticle surface chemically adsorbs but the adsorbed molecules does not show a dissociation reaction. Moreover the Rh nanoparticles does not show the hydrogen absorbing/releasing reaction. On the other hand, for the Pd nanoparticles, it is found that the hydrogen absorbing/releasing reaction rate is remarkably slow in comparison with the rate for without sulfur poisoning. Based on this result, we are planning to continue applying to cancer screening in the future.
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Report
(4 results)
Research Products
(21 results)
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[Presentation] Fabrication of Au nanorods by solution plasma method2015
Author(s)
Chie Tsukada, Tsuyoshi Mizutani, Satoshi Ogawa, Hirofumi Nameki, Shinya Yagi
Organizer
10th International Symposium on Atomic Level Characterizations for New Materials and Devices ’15
Place of Presentation
Nagoya University, Nagoya, Aichi, Japan
Year and Date
2015-10-25
Related Report
Int'l Joint Research
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