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Physiological Polymorphism of thermogenesis during cold exposure

Research Project

Project/Area Number 26291097
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypePartial Multi-year Fund
Section一般
Research Field Applied anthropology
Research InstitutionKyushu University (2015-2017)
Hokkaido University (2014)

Principal Investigator

Maeda Takafumi  九州大学, 芸術工学研究院, 教授 (90301407)

Co-Investigator(Kenkyū-buntansha) 西村 貴孝  長崎大学, 医歯薬学総合研究科(医学系), 助教 (80713148)
Project Period (FY) 2014-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥16,120,000 (Direct Cost: ¥12,400,000、Indirect Cost: ¥3,720,000)
Fiscal Year 2016: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2015: ¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000)
Fiscal Year 2014: ¥6,110,000 (Direct Cost: ¥4,700,000、Indirect Cost: ¥1,410,000)
Keywords生理人類学 / 環境適応能 / 生理的多型性 / 体温調節 / 産熱反応 / 代謝機能 / 全身耐寒性
Outline of Final Research Achievements

The purpose of this study was to examine individual differences and their influence factors from the patterns of cold-induced non-shivering and shivering thermogenesis. Adult males participated to this study, and they exposed to cold environment which air temperature was falling from 28 degrees to 15 or 5 degrees for 90 min. Measurements were the rectal and skin temperatures, expired gas analysis value, electromyogram(EMG), etc during cold exposure. The cold-induced thermogenesis was quantified from oxygen intake and carbon dioxide emissions obtained from exhalation gas analysis, and was divided into non-shivering and shivering thermogenesis by EMG. From the pattern of thermogenic reaction, it became possible to divide into three types, which were non-shivering thermogenesis by brown adipose tissue, non-shivering by other effector than brown adipose tissue, and shivering thermogenesis type. It was possible to evaluate physiological polymorphism in cold - induced heat production.

Report

(5 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Annual Research Report
  • 2015 Annual Research Report
  • 2014 Annual Research Report
  • Research Products

    (17 results)

All 2018 2017 2016 2015 2014

All Journal Article (3 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results,  Acknowledgement Compliant: 2 results) Presentation (14 results) (of which Int'l Joint Research: 5 results,  Invited: 5 results)

  • [Journal Article] Relationship between maximum oxygen uptake and peripheral vasoconstriction in a cold environment2017

    • Author(s)
      Takafumi Maeda
    • Journal Title

      Journal of Physiological Anthropology

      Volume: 36 Issue: 1 Pages: 42-42

    • DOI

      10.1186/s40101-017-0158-2

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 寒冷誘発熱産生の季節差と影響要因の検討2015

    • Author(s)
      鷹野翔一、小林功嗣、前田享史
    • Journal Title

      空気調和・衛生工学会第49回北海道支部学術講演会論文集

      Volume: 49 Pages: 23-26

    • Related Report
      2014 Annual Research Report
    • Acknowledgement Compliant
  • [Journal Article] 寒冷誘発非ふるえ熱産生反応の個人差および季節差の検討2015

    • Author(s)
      小林功嗣、鷹野翔一、前田享史
    • Journal Title

      空気調和・衛生工学会第49回北海道支部学術講演会論文集

      Volume: 49 Pages: 39-42

    • Related Report
      2014 Annual Research Report
    • Acknowledgement Compliant
  • [Presentation] 寒冷環境への適応2018

    • Author(s)
      前田享史
    • Organizer
      応用生理人類学研究センターシンポジウム「現代人の環境適応能 ~生理人類学の視点から~」
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] Effects of seasonal change in basal metabolic rate on the seasonal difference in cold-induced thermogenesis.2017

    • Author(s)
      Takafumi Maeda
    • Organizer
      The 13th International Congress of Physiological Anthropology
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Relationship between endothelium-dependent vasodilation and cold-induced vasodilation2017

    • Author(s)
      Takafumi Maeda
    • Organizer
      The 17th International Conference on Environmental Ergonomics
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Individual Variation in Thermogenesis during Cold Exposure2016

    • Author(s)
      Maeda Takafumi, Hayashi Masanobu
    • Organizer
      20th Congress of the European Anthropological Association
    • Place of Presentation
      University of Zagreb, Zagreb, Croatia
    • Year and Date
      2016-08-24
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 寒冷時の産熱反応における生理的多型性2016

    • Author(s)
      前田 享史
    • Organizer
      豊田中央研究所講演会
    • Place of Presentation
      豊田中央研究所
    • Year and Date
      2016-02-16
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] ヒトの耐寒性とその影響要因2016

    • Author(s)
      前田 享史
    • Organizer
      人類学若手の会第4回総合研究集会
    • Place of Presentation
      九州大学大橋キャンパス
    • Year and Date
      2016-02-06
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] Cold Adaptability in Human, Immune Function and Environmental Condition, Thermal Stimuli and Mental Task Performance2016

    • Author(s)
      Maeda Takafum
    • Organizer
      Research Seminar of NUTRIM School of Nutrition and Translational Research in Metabolism in Maastricht University
    • Place of Presentation
      Maastricht University, The Netherland
    • Year and Date
      2016-01-19
    • Related Report
      2015 Annual Research Report
  • [Presentation] Phenotype of Cold-Induced Thermogenic Resposes2015

    • Author(s)
      Maeda Takafumi
    • Organizer
      The 12th International Congress of Physiological Anthropology
    • Place of Presentation
      Tokyo Bay Makuhari Hall
    • Year and Date
      2015-10-27
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Relationship between Brown Adipose Tissue Activity and Subcutaneous Tissue Temperature of Supraclavicular Region during Mild Cold Exposure2015

    • Author(s)
      Kobayashi Koji, Maeda Takafumi, Yoneshiro Takeshi, Matsushita Mami, Saito Masayuki
    • Organizer
      The 12th International Congress of Physiological Anthropology
    • Place of Presentation
      Tokyo Bay Makuhari Hall
    • Year and Date
      2015-10-27
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 子どもの体温調節機能2015

    • Author(s)
      前田 享史
    • Organizer
      日本家政学会被服衛生学部会 第34回被服衛生学セミナー
    • Place of Presentation
      玄海ロイヤルホテル
    • Year and Date
      2015-08-28
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] 寒冷曝露時の鎖骨上窩皮下組織温と褐色脂肪活性の関係2015

    • Author(s)
      小林功嗣, 鷹野翔一, 高屋敷亮太, 前田 享史, 米代武司, 松下真美, 斉藤昌之
    • Organizer
      日本生理人類学会第72回大会
    • Place of Presentation
      北海道大学医学部学友会館「フラテ」
    • Year and Date
      2015-05-30
    • Related Report
      2015 Annual Research Report
  • [Presentation] Effect of seasonal variation in basal metabolic rate on cold-induced thermogenesis2015

    • Author(s)
      Takafumi Maeda, Shoichi Takano, Hiroki Sakurai
    • Organizer
      International Symposium on Human Adaptation to Environment and Whole-body Coordination
    • Place of Presentation
      神戸大学
    • Year and Date
      2015-03-14 – 2015-03-16
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 寒冷曝露時の産熱反応と鎖骨上部・大腿部皮下温の関係2014

    • Author(s)
      鷹野翔一、前田享史、小林功嗣
    • Organizer
      日本生理人類学会第71回大会
    • Place of Presentation
      神戸大学
    • Year and Date
      2014-11-01 – 2014-11-02
    • Related Report
      2014 Annual Research Report
  • [Presentation] Seasonal variation in basal metabolic rate and thermogenic response to cold2014

    • Author(s)
      Takafumi Maeda, Hiroki Sakurai, Shoichi Takano
    • Organizer
      19th Congress of the European Anthropological Association
    • Place of Presentation
      Moscow, Russia
    • Year and Date
      2014-08-25 – 2014-08-29
    • Related Report
      2014 Annual Research Report

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Published: 2014-04-04   Modified: 2019-03-29  

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