• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Exploration of mechanism underlying differentiation to brown/brite adipocytes in fat depots of fattening cattle

Research Project

Project/Area Number 26292137
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypePartial Multi-year Fund
Section一般
Research Field Animal production science
Research InstitutionKyoto University

Principal Investigator

Matsui Tohru  京都大学, (連合)農学研究科(研究院), 教授 (40181680)

Co-Investigator(Kenkyū-buntansha) 友永 省三  京都大学, (連合)農学研究科(研究院), 助教 (00552324)
Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥15,990,000 (Direct Cost: ¥12,300,000、Indirect Cost: ¥3,690,000)
Fiscal Year 2016: ¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2015: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2014: ¥7,020,000 (Direct Cost: ¥5,400,000、Indirect Cost: ¥1,620,000)
Keywords褐色脂肪細胞 / Brite細胞 / ウシ / ビタミンA / 畜産学 / 応用動物 / 生体機能利用 / ビタミンA
Outline of Final Research Achievements

We established culture condition to differentiate stromal-vascular cells originated from bovine adipose tissues to brite (brown in white) adipocytes. Retinoic acid had an inhibitory effect on expression of Ucp1, a gene predominantly expressed in brite adipocytes. Feeding vitamin A-restricted diet did not affect expression level in adipose tissues of Japanese Black fattening cattle. However, Ucp1 expression was slightly higher in brite adipocytes differentiated from stromal vascular cells isolated from vitamin A-restricted cattle than in those from control cattle.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Annual Research Report
  • 2014 Annual Research Report

Research Products

(9 results)

All 2017 2016 2015 2014

All Journal Article (4 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 4 results,  Open Access: 2 results,  Acknowledgement Compliant: 4 results) Presentation (5 results) (of which Int'l Joint Research: 1 results)

  • [Journal Article] Expression of uncoupling protein 1 in bovine muscle cells.2016

    • Author(s)
      Abd Eldaim MA, Hashimoto O, Ohtsuki H, Yamada T, Murakami M, Onda K, Sato R, Kanamori Y, Qiao Y, Tomonaga S, Matsui T, Funaba M
    • Journal Title

      Journal of Animal Science

      Volume: 94 Pages: 5097-5104

    • DOI

      10.2527/jas.2016-0726

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Dietary regulation of Ucp2 and Ucp3 expressions in white adipose tissues of beef cattle.2016

    • Author(s)
      Shigematsu M, Yamada T, Wong YY, Kanamori Y, Murakami M, Fujimoto Y, Suzuki M, Kida R, Qiao Y, Tomonaga S, Matsui T, Funaba M.
    • Journal Title

      Can J Anim Sci.

      Volume: 96 Pages: 457-460

    • DOI

      10.1139/cjas-2016-0020

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Presence of brown/beige adipocytes in adipose tissues of fattening cattle and diet-related changes in their activity.2016

    • Author(s)
      Funaba M, Yamada T, Hashimoto O, Murakami M, Kanamori Y, Matsui T.
    • Journal Title

      Proc Jpn Soc Anim Nutr Metab.

      Volume: 60 Pages: 85-97

    • NAID

      40020901925

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Regulatory expression of components in the BMP pathway in white adipose tissues of cattle2015

    • Author(s)
      Yuhang Qiao, Tomoya Yamada, Yohei Kanamori, Ryosuke Kida, Mei Shigematsu, Yusuke Fujimoto, Shozo Tomonaga, Tohru Matsui, Masayuki Funaba
    • Journal Title

      Livestock Science

      Volume: 174 Pages: 144-149

    • DOI

      10.1016/j.livsci.2015.02.008

    • NAID

      120005623242

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] 黒毛和種去勢肥育牛におけるビタミンAコントロールが肉質に及ぼす影響について2017

    • Author(s)
      吉岡秀貢、糸山恵理奈、北村祥子、長瀬祐士、村上弘明、 星野洋一郎、松井 徹.
    • Organizer
      総合技術研究会2017東京大学
    • Place of Presentation
      東京
    • Year and Date
      2017-03-08
    • Related Report
      2016 Annual Research Report
  • [Presentation] Presence of brown/beige adipocytes in adipose tissues of fattening cattle and diet-related changes in their activity.2016

    • Author(s)
      Funaba M, Yamada T, Hashimoto O, Murakami M, Kanamori Y, Matsui T.
    • Organizer
      17th AAAP Animal Science Congress
    • Place of Presentation
      福岡
    • Year and Date
      2016-08-22
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 黒毛和種去勢牛の脂肪組織由来間質脈管系細胞から分化誘導した脂肪細胞はUCP1を発現する2016

    • Author(s)
      喬 宇航、村上 賢、友永省三、舟場正幸、松井 徹
    • Organizer
      第121回日本畜産学会
    • Place of Presentation
      日本獣医生命科学大学
    • Year and Date
      2016-03-27
    • Related Report
      2015 Annual Research Report
  • [Presentation] 肥育牛脂肪組織では給与飼料によってUCP2,3発現が変化する2015

    • Author(s)
      Wong Yun Yi、山田知哉、金森燿平、重松芽衣、冨士本有祐、木田龍祐、喬宇航、友永省三、舟場正幸、松井徹
    • Organizer
      第65回関西畜産学会
    • Place of Presentation
      愛媛大学
    • Year and Date
      2015-09-03
    • Related Report
      2015 Annual Research Report
  • [Presentation] ウシ白色脂肪組織中におけるTGF-βファミリーの発現2014

    • Author(s)
      喬 宇航・山田知哉・金森耀平・木田龍祐・重松芽衣・冨士本有祐・友永省三・舟場正幸・松井 徹
    • Organizer
      第64回関西畜産学会大会
    • Place of Presentation
      広島大学生物生産学部
    • Year and Date
      2014-09-08 – 2014-09-09
    • Related Report
      2014 Annual Research Report

URL: 

Published: 2014-04-04   Modified: 2018-03-22  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi