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Canine behavior genetics: toward understanding of genetic background on aggression

Research Project

Project/Area Number 26292163
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypePartial Multi-year Fund
Section一般
Research Field Integrative animal science
Research InstitutionThe University of Tokyo

Principal Investigator

Takeuchi Yukari  東京大学, 大学院農学生命科学研究科(農学部), 教授 (10240730)

Research Collaborator Mori Yuji  
Momozawa Yukihide  
Arata Sayaka  
Project Period (FY) 2014-04-01 – 2019-03-31
Project Status Completed (Fiscal Year 2018)
Budget Amount *help
¥15,860,000 (Direct Cost: ¥12,200,000、Indirect Cost: ¥3,660,000)
Fiscal Year 2018: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2017: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2016: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2015: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2014: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Keywords行動学 / 気質 / 攻撃性 / SNP / 犬 / ゲノム
Outline of Final Research Achievements

In this study, we developed an original questionnaire specifically for canine aggression and temperament evaluation. We collected blood samples with questionnaire responses of 372 Chihuahuas and 537 Toy Poodles from dog owners. From the genome-wide association study for the specific phenotypes after examining the results of questionnaire responses, we were able to list a part of the genetic polymorphisms related to certain aggressions by sub-classifying aggression as being either related to temperament or motivation.

Academic Significance and Societal Importance of the Research Achievements

本研究によって犬の攻撃性に関わる感受性遺伝子多型がリストアップされれば,診断に際して臨床経験に頼りがちな動物の行動疾患に対する客観的な診断方法の確立に資するだけではなく,感受性多型の機能解析により攻撃性に対する新規治療法開発の道が拓かれることになる。また,本研究が進展すれば,犬の問題行動治療という観点に留まらず,攻撃性が不適正とみなされる身体障害者補助犬の育成効率の改善や動物福祉に配慮した飼育方法の見直し,といった予防・制御的観点からも意義が大きいと考えられる。

Report

(6 results)
  • 2018 Annual Research Report   Final Research Report ( PDF )
  • 2017 Annual Research Report
  • 2016 Annual Research Report
  • 2015 Annual Research Report
  • 2014 Annual Research Report

Research Products

(7 results)

All 2019 2018 2016 2014 Other

All Journal Article (2 results) (of which Peer Reviewed: 2 results,  Open Access: 2 results,  Acknowledgement Compliant: 2 results) Presentation (3 results) (of which Invited: 1 results) Remarks (2 results)

  • [Journal Article] Microsatellite loci analysis for individual identification in Shiba Inu2016

    • Author(s)
      Arata S., Asahi A., Takeuchi Y., Mori Y.
    • Journal Title

      J. Vet. Med. Sci.

      Volume: 78 Issue: 3 Pages: 439-441

    • DOI

      10.1292/jvms.15-0579

    • NAID

      130005140883

    • ISSN
      0916-7250, 1347-7439
    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] "Reactivity to stimuli" is a temperamental factor contributing to canine aggression2014

    • Author(s)
      Arata, S., Takeuchi, Y., Inoue, M. and Mori, Y.
    • Journal Title

      PLoS One

      Volume: 9

    • DOI

      10.1371/journal.pone.0100767

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Presentation] 日本の家庭猫における問題行動-ウェブアンケートを用いた発症率及び発症要因の調査-2019

    • Author(s)
      山田良子、荒田明香、清川泰志、武内ゆかり
    • Organizer
      第25回ヒトと動物の関係学会学術集会
    • Related Report
      2018 Annual Research Report
  • [Presentation] 日本の家庭犬における問題行動の発症率および発症要因に関する調査2018

    • Author(s)
      山田良子、荒田明香、清川泰志、武内ゆかり
    • Organizer
      第161回日本獣医学会学術集会
    • Related Report
      2018 Annual Research Report
  • [Presentation] イヌの行動遺伝学2018

    • Author(s)
      武内ゆかり
    • Organizer
      在来家畜研究会・日本動物遺伝育種学会合同シンポジウム
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Remarks] 獣医動物行動学研究室研究概要

    • URL

      http://www.vm.a.u-tokyo.ac.jp/koudou/j-research.html

    • Related Report
      2018 Annual Research Report 2017 Annual Research Report
  • [Remarks] 獣医動物行動研究概要

    • URL

      http://www.vm.a.u-tokyo.ac.jp/koudou/j-research.html

    • Related Report
      2016 Annual Research Report 2015 Annual Research Report 2014 Annual Research Report

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Published: 2014-04-04   Modified: 2020-03-30  

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