• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Epidemiological studies on paragonimus westermaniasis in Asia based on the PK gene

Research Project

Project/Area Number 26305011
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypePartial Multi-year Fund
Section海外学術
Research Field Parasitology (including sanitary zoology)
Research InstitutionKochi University

Principal Investigator

AGATSUMA Takeshi  高知大学, 医学部, 特任教授 (40117031)

Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥11,830,000 (Direct Cost: ¥9,100,000、Indirect Cost: ¥2,730,000)
Fiscal Year 2016: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Fiscal Year 2015: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2014: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Keywordsウエステルマン肺吸虫 / フォスファーゲンキナーゼ遺伝子 / イントロン / ミトコンドリアDNA / 人獣共通感染症 / 東南アジア / 尿検査 / ウエステルマン肺吸虫の起源 / フォスファーゲンキナーゼ / DNA / 分子系統 / アジア / インド / スリランカ / PKD1イントロン3 / タイ / フィリピン / PCR
Outline of Final Research Achievements

In this study, nucleotide sequences of Pk intron (nuclear DNA) in Paragonimus westermani were used to construct phylogenetic trees. As a result, it was discovered that the India and Sri Lankan clades have been diverged from the other Asian clades of P. westermani considerably long time ago. In addition, it became clear that two clades from Malaysia and Philippines was included in the East Asia clade. Phylogenetic tree obtained from this intron region became quite different from the tree using mitochondrial DNA (cox1). Furthermore, it was considered that a lot of mutation of the Pk intron position has been created by the recombination events between different alleles, indicating a single event of triploid origin. Both of the India and Sri Lankan clades could be separate species from P. westermani.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Annual Research Report
  • 2014 Annual Research Report
  • Research Products

    (14 results)

All 2017 2016 2015 Other

All Int'l Joint Research (5 results) Journal Article (7 results) (of which Int'l Joint Research: 6 results,  Peer Reviewed: 6 results,  Open Access: 6 results,  Acknowledgement Compliant: 1 results) Presentation (2 results)

  • [Int'l Joint Research] Mahasarakham University(Thailand)

    • Related Report
      2016 Annual Research Report
  • [Int'l Joint Research] Ministry of Health(Cambodia)

    • Related Report
      2016 Annual Research Report
  • [Int'l Joint Research] マハサラカム大学(タイ)

    • Related Report
      2015 Annual Research Report
  • [Int'l Joint Research] 国立医学研究所デイブルガー支部(インド)

    • Related Report
      2015 Annual Research Report
  • [Int'l Joint Research] ペラデニア大学(スリランカ)

    • Related Report
      2015 Annual Research Report
  • [Journal Article] Morphological and molecular characteristics of Malayfilaria sofiani Uni, Mat Udin & Takaoka n. g., n. sp. (Nematoda: Filarioidea) from the common treeshrew Tupaia glis Diard & Duvaucel (Mammalia: Scandentia) in Peninsular Malaysia2017

    • Author(s)
      Uni S, Mat Udin AS, Agatsuma T, Saijuntha W, Junker K, Ramli R, Omar H, Lim YA, Sivanandam S, Lefoulon E, Martin C, Belabut DM, Kasim S, Abdullah Halim MR, Zainuri NA, Bhassu S, Fukuda M, Matsubayashi M, Harada M, Low VL, Chen CD, Suganuma N, Hashim R, Takaoka H, Azirun MS
    • Journal Title

      Parasite Vectors

      Volume: 10 Issue: 1 Pages: 1-14

    • DOI

      10.1186/s13071-017-2105-9

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Genetic diversity within and among gelada (Theropithecus gelada) populations based on mitochondrial DNA analysis2017

    • Author(s)
      Takayoshi Shotake, Weerachai Saijuntha, Takeshi Agatsuma, Yoshi Kawamoto
    • Journal Title

      Anthropological Science

      Volume: 124 Issue: 3 Pages: 157-167

    • DOI

      10.1537/ase.160717

    • NAID

      130005251320

    • Related Report
      2016 Annual Research Report
    • Open Access / Int'l Joint Research
  • [Journal Article] Arginine kinase in Toxocara canis: Exon-intron organization, functional analysis of site-directed mutants and evaluation of putative enzyme inhibitors2016

    • Author(s)
      Susiji Wickramasinghe, Lalani Yatawara, Mitsuru Nagataki, Takeshi Agatsuma
    • Journal Title

      Asian Pacific Journal of Tropical Medicine

      Volume: 9 Issue: 10 Pages: 995-1001

    • DOI

      10.1016/j.apjtm.2016.07.023

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Rodents as a Source of Salmonella Contamination in Wet Markets in Thailand2016

    • Author(s)
      Ribas A, Saijuntha W, Agatsuma T, Prantlova; V, Poonlaphdecha S.
    • Journal Title

      Vector Borne Zoonotic Dis

      Volume: 16 Issue: 8 Pages: 537-540

    • DOI

      10.1089/vbz.2015.1894

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Intron sequence of the taurocyamine kinase gene as a marker to investigate genetic variation of Paragonimus species in Japan and the origins of triploidy in P. westermani.2016

    • Author(s)
      Saijuntha W, Tantrawatpan C, Jarilla BR, Agatsuma T, Andrews RH, Petney TN.
    • Journal Title

      Trans R Soc Trop Med Hyg.

      Volume: 110 Issue: 1 Pages: 67-73

    • DOI

      10.1093/trstmh/trv109

    • Related Report
      2016 Annual Research Report 2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Mitochondrial DNA sequences of 37 collar-spined echinostomes (Digenea: Echinostomatidae) in Thailand and Lao PDR reveals presence of two species: Echinostoma revolutum and E. miyagawai.2015

    • Author(s)
      M. Nagataki, C. Tantrawatpan, T. Agatsuma, T. Sugiura, K. Duenngai, P. Sithithaworn, R. H. Andrews, T. N. Petney, W. Saijuntha
    • Journal Title

      Infection, Genetics and Evolution

      Volume: 35 Pages: 56-62

    • DOI

      10.1016/j.meegid.2015.07.022

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Onchocerca takaokai n. sp. (Nematoda: Filarioidea) in Japanese wild boars (Sus scrofa leucomystax): Description and molecular identification of intradermal females2015

    • Author(s)
      Shigehiko Uni, Masako Fukuda, Takeshi Agatsuma, Odile Bain, Yasushi Otsuka, Jun Nakatani, Makoto Matsubayashi, Masashi Harada, Hasmahzaiti Omar, Rosli Ramli, Rosli Hashim, Mohd Sofian Azirun, Hiroyuki Takaoka
    • Journal Title

      Parasitology International

      Volume: 64 Issue: 6 Pages: 493-502

    • DOI

      10.1016/j.parint.2015.07.001

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Presentation] 西日本における肺吸虫第二中間宿主サワガニの分子生物地理学的研究2016

    • Author(s)
      Weerachai Sajuntha、古屋八重子、山岡遵、産田孝、岩代洋子、吾妻健
    • Organizer
      第109回土佐生物学会大会
    • Place of Presentation
      高知大学(高知県高知市)
    • Year and Date
      2016-12-17
    • Related Report
      2016 Annual Research Report
  • [Presentation] フォスファーゲンキナーゼ遺伝子から見た、 住血吸虫の系統関係と推定分岐年代2016

    • Author(s)
      吾妻 健、Weerachai Saijuntha
    • Organizer
      第72回日本寄生虫学会西日本支部大会
    • Place of Presentation
      岐阜大学サテライトキャンパス(岐阜県岐阜市)
    • Year and Date
      2016-10-15
    • Related Report
      2016 Annual Research Report

URL: 

Published: 2014-04-04   Modified: 2018-03-22  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi