Development of new successful aging model for super aging society

• Project/Area Number: 26310104
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Partial Multi-year Fund
• Section: 特設分野
• Research Field: Neo-Gerontology
• Research Institution: Osaka University
• Principal Investigator: Gondo Yasuyuki 大阪大学, 人間科学研究科, 准教授 (40250196)
• Co-Investigator(Kenkyū-buntansha): 新井 康通 慶應義塾大学, 医学部, 講師 (20255467) ; 石崎 達郎 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究部長 (30246045) ; 池邉 一典 大阪大学, 歯学研究科(研究院), 准教授 (70273696) ; 神出 計 大阪大学, 医学(系)研究科(研究院), 教授 (80393239) ; 片桐 恵子 神戸大学, 人間発達環境学研究科, 准教授 (80591742)
• Co-Investigator(Renkei-kenkyūsha): MASUI Yukie 東京都健康長寿医療センター研究所, 研究員 (10415507) ; NAKAGAWA Takeshi 大阪大学, 人間科学研究科, 助教 (60636942) ; INAGAKI Hiroki 東京都健康長寿医療センター研究所, 研究員 (00311407) ; UEDA Hiroshi 大阪大学, 人間科学研究科, 講師 (20595293)
• Project Period (FY): 2014-07-18 – 2017-03-31
• Project Status: Completed (Fiscal Year 2016)
• Budget Amount: ¥16,510,000 (Direct Cost: ¥12,700,000、Indirect Cost: ¥3,810,000); Fiscal Year 2016: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000); Fiscal Year 2015: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000); Fiscal Year 2014: ¥7,280,000 (Direct Cost: ¥5,600,000、Indirect Cost: ¥1,680,000)
• Keywords: 高齢期 / サクセスフルエイジング / SONIC研究 / 主観的幸福感 / 補償 / 超高齢者 / 縦断研究

Outline of Final Research Achievements

This study aimed to develop a new Successful Aging model for super aging society. We adapted several successful aging model with different definition on the data from longitudinal epidemiological study. Results indicated only 17%, 4%, 0% of participants were classified as successful ager for 70, 80 and 90 years old respectively, if we applied classical definition based on physical function. On the other hand, age related increase in subjective well-being was observed. This trend was also observed in 3-year longitudinal change. We could confirm dissociation between successful aging model based on physical function and subjective well-being.

Research Products

• [Int'l Joint Research] University of Hawaii/California Pacific Medical Center/Johns Hopkins University(USA)
• [Int'l Joint Research] University of Lausanne(Switzerland)
• [Int'l Joint Research] Fordham University(USA)
• [Int'l Joint Research] Heidelberg University(Germany)
• [Journal Article] Longitudinal study of factors affecting taste sense decline in old-old individuals. (2017)
  • Author(s): Ogawa T, Uota M, Ikebe, K., Arai, Y., Kamide, K., Gondo Y, Masui, Y, Ishizaki T, Inomata C, Takeshita H, Mihara Y, Hatta K, Maeda Y.
  • Journal Title: J Oral Rehabil Volume: in press Pages: 22-29
  • DOI: 10.1111/joor.12454
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Factors related to taste sensitivity in elderly: cross-sectional findings from SONIC study. (2017)
  • Author(s): Uota M, Ogawa T, Ikebe, K., Arai, Y., Kamide, K., Gondo Y, Masui, Y, Ishizaki T, Inomata C, Takeshita H, Mihara Y, Maeda Y
  • Journal Title: J Oral Rehabil. Volume: in press Pages: 1292-1300
  • DOI: 10.1111/joor.12442
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] 百寿者研究から見た望ましい老いのあり方 (2017)
  • Author(s): 権藤恭之
  • Journal Title: 環境と健康 Volume: Vol.30 No.1 Pages: 14-23
• [Journal Article] 老年的超越の発達を促す社会的側面 (2017)
  • Author(s): 権藤恭之
  • Journal Title: Geriatric Medicine（老年医学） Volume: 55(2) Pages: 151-154
• [Journal Article] ICC-dementia (International Centenarian Consortium - dementia): an international consortium to determine the prevalence and incidence of dementia in centenarians across diverse ethnoracial and sociocultural groups (2016)
  • Author(s): Brodaty, H., Woolf, C., Andersen, S., Barzilai, N., Brayne, C., Cheung, K.S., Corrada, M.M., Crawford, J.D., Daly, C., Gondo, Y., Hagberg, B., Hirose, N., Holstege, H., Kawas, C., Kaye, J., Kochan, N.A., Lau, B.H., Lucca, U., Marcon, G., Martin, P., Poon, L.W., Richmond, R., Robine, J.M., Skoog, I., et al.
  • Journal Title: BMC Neurology Volume: 21
  • DOI: 10.1186/s12883-016-0569-4
  • Peer Reviewed
• [Journal Article] 余暇活動と認知機能の関連－地域在住高齢者を対象として (2016)
  • Author(s): 小園麻里菜, 権藤恭之, 小川まどか, 石岡良子, 増井幸恵, 中川威, 田渕恵, 立平起子, 池邉一典, 神出計, 新井康通, 石崎達郎, 高橋龍太郎
  • Journal Title: 老年社会科学 Volume: 38(1) Pages: 32-44
  • Peer Reviewed
• [Journal Article] Association of Occlusal Force with Cognition in Independent Older Japanese People (2016)
  • Author(s): Ogawa T, Uota M, Ikebe, K., Arai, Y., Kamide, K., Gondo Y, Masui, Y, Ishizaki T, Inomata C, Takeshita H, Mihara Y, Hatta K, Maeda Y.
  • Journal Title: JDR Clinical & Translational Research Volume: 1(1) Pages: 69-76
  • Peer Reviewed
• [Journal Article] Association Analysis of FOXO3 Longevity Variants With Blood Pressure and Essential Hypertension (2016)
  • Author(s): Morris BJ1, Chen R2, Donlon TA2, Evans DS3, Tranah GJ3, Parimi N3, Ehret GB4, Newton-Cheh C5, Seto T6, Willcox DC7, Masaki KH8, Kamide K9, Ryuno H10, Oguro R11, Nakama C11, Kabayama M10, Yamamoto K11, Sugimoto K11, Ikebe K12, Masui Y13, Arai Y14, Ishizaki T13, Gondo Y15, Rakugi H11, Willcox BJ8.
  • Journal Title: American Journal of Hypertension Volume: in press Pages: 1292-1300
  • DOI: 10.1093/ajh/hpv171
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] SONIC Study: A Longitudinal Cohort Study of the Older People as Part of a Centenarian Study (2016)
  • Author(s): Gondo,Y., Masui, Y., Kamide, K.., Ikebe, K.., Arai,Y., and Ishizaki, T.
  • Journal Title: Encyclopedia of Geropsychology Volume: -
  • DOI: 10.1007/978-981-287-080-3_182-1
• [Journal Article] Cognition (2016)
  • Author(s): Ishioka, Y. and Gondo, Y
  • Journal Title: Encyclopedia of Geropsychology Volume: -
  • DOI: 10.1007/978-981-287-080-3_185-1
• [Journal Article] Effects of the APOE ε4 Allele and Education on Cognitive Function in Japanese Centenarians. (2016)
  • Author(s): Ishioka, YL, Gondo Y, Fuku N, Inagaki H, Masui, Y, Takayama M, Abe Y, Arai, Y., Hirose N
  • Journal Title: Age (Dordr) Volume: - Pages: 495-503
  • DOI: 10.1007/s11357-016-9944-8
  • Peer Reviewed / Open Access
• [Journal Article] Tokyo Centenarian Study and Japan Semi-supercentenarian Study (2016)
  • Author(s): Inagaki, H., Arai, Y.., Gondo, Y., and Hirose, N.
  • Journal Title: Encyclopedia of Geropsychology Volume: -
  • DOI: 10.1007/978-981-287-080-3_240-1
• [Journal Article] 超高齢期の心理的特徴―幸福感に関する知見― (2016)
  • Author(s): 権藤恭之
  • Journal Title: Aging & Health Volume: 23 Pages: 28-31
• [Journal Article] Association of Occlusal Force with Cognition in Independent Older Japanese People (2016)
  • Author(s): 2.Takeshita H, Ikebe K, Kagawa R, Okada T, Gondo Y, Nakagawa T, Ishioka Y, Inomata C, Tada S, Matsuda K, Kurushima Y, Enoki K, Kamide K, Masui Y, Takahashi R, Arai Y, Maeda Y.
  • Journal Title: JDR Clinical & Translational Research, Volume: 43(3) Pages: 342-349
  • DOI: 10.1016/j.jdent.2014.12.011
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] The association between lower occlusal force and slower walking speed mediated by less protein intake: from SONIC study. (2015)
  • Author(s): Okada T, Ikebe K, Kagawa R, Inomata C, Takeshita H, Gondo Y, Ishioka Y, Okubo H, Kamide K, Masui Y, Takahashi R, Arai Y, Thomson WM, Maeda Y.
  • Journal Title: Journal of American Geriatric Society Volume: 63 Pages: 2382-2387
  • DOI: 10.1111/jgs.13784
  • Peer Reviewed / Open Access
• [Journal Article] Occupational complexity and late-life memory and reasoning abilities (2015)
  • Author(s): 石岡良子, 権藤恭之, 増井幸恵, 中川威, 田渕恵, 小川まどか, 神出計, 池邉一典, 新井康通, 石崎達郎, 髙橋龍太郎
  • Journal Title: JJ pshicho Volume: 83 Issue: 3 Pages: 219-229
  • DOI: 10.4992/jjpsy.86.14007
  • NAID: 130005095281
  • ISSN: 0021-5236, 1884-1082
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Disease-associated polymorphisms in 9p21 are not associated with extreme longevity. (2015)
  • Author(s): Congrains A, Kamide K, Hirose N, Arai Y, Oguro R, Nakama C, Imaizumi Y, Kawai T, Kusunoki H, Yamamoto H, Onishi-Takeya M, Takeya Y, Yamamoto K, Sugimoto K, Akasaka H, Saitoh S, Miura T, Awata N, Kato N, Katsuya T, Ikebe K, Gondo Y, Rakugi H.
  • Journal Title: Geriatrics & Gerontology International. Volume: 15 Pages: 797-803
  • DOI: 10.1111/ggi.12346
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Association of personality traits with oral health-related quality of life independently of objective oral health status: A study of community-dwelling elderly Japanese. (2015)
  • Author(s): Takeshita H, Ikebe K, Kagawa R, Okada T, Gondo Y, Nakagawa T, Ishioka Y, Inomata C, Tada S, Matsuda K, Kurushima Y, Enoki K, Kamide K, Masui Y, Takahashi R, Arai Y, & Maeda Y.
  • Journal Title: Journal of dentistry Volume: 43 Pages: 342-349
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Interdisciplinary approach of studying healthy aging and longevity based on the social gerontology (2014)
  • Author(s): 権藤恭之
  • Journal Title: Jpn J Geriat Volume: 51 Issue: 1 Pages: 35-38
  • DOI: 10.3143/geriatrics.51.35
  • NAID: 130004917133
  • ISSN: 0300-9173
  • Open Access
• [Presentation] 自己調節方略のライフコース（４）―将来の研究の展望― (2017)
  • Author(s): 権藤恭之、竹村明子、松岡弥玲、中川威、増井幸恵
  • Organizer: 日本発達心理学会
  • Place of Presentation: 広島国際会議場
  • Year and Date: 2017-03-25
• [Presentation] 年を取ることは、ポジィティブなことなのか (2017)
  • Author(s): 権藤恭之
  • Organizer: 日本人間工学会関西支部春季講演会
  • Place of Presentation: 大阪工業大学
  • Year and Date: 2017-03-25
  • Invited
• [Presentation] Introduction to Centenarian Studies in Asia and the US (2016)
  • Author(s): Yasuyuki Gondo
  • Organizer: Are Centenarians the Realisation of Successful Ageing: Insights From a Global Study on Centenarians
  • Place of Presentation: Duke-NUS Medical School
  • Year and Date: 2016-12-07
  • Int'l Joint Research / Invited
• [Presentation] Maintaining Well-Being is Key to Successful Ageing Among Centenarians (2016)
  • Author(s): Yasuyuki Gondo
  • Organizer: Are Centenarians the Realisation of Successful Ageing: Insights From a Global Study on Centenarians
  • Place of Presentation: Duke-NUS Medical School
  • Year and Date: 2016-12-07
  • Int'l Joint Research / Invited
• [Presentation] Case Study of the Longest Lived Man in Japan (2016)
  • Author(s): Yasuyuki Gondo
  • Organizer: Are Centenarians the Realisation of Successful Ageing: Insights From a Global Study on Centenarians
  • Place of Presentation: Duke-NUS Medical School
  • Year and Date: 2016-12-07
  • Int'l Joint Research / Invited
• [Presentation] 性格傾向と長寿の関係を食行動は媒介するのか。―高齢期における性格特性と食品摂取パターンとの関連― (2016)
  • Author(s): 権藤恭之
  • Organizer: 日本臨床栄養学会
  • Place of Presentation: 大阪国際会議場
  • Year and Date: 2016-10-07
  • Invited
• [Presentation] Developing a new successful model for super-aging society: The example of Japan. (2016)
  • Author(s): Gondo, Y.
  • Organizer: Swiss Society of Gerontology
  • Place of Presentation: Fribourg, Switzerland
  • Year and Date: 2016-01-27
  • Int'l Joint Research / Invited
• [Presentation] Overview about Japanese centenarian studies. (2015)
  • Author(s): Gondo Y.
  • Organizer: International Centenarian Consortium meeting
  • Place of Presentation: Cagliari, Italy
  • Year and Date: 2015-06-18
  • Int'l Joint Research
• [Presentation] Findings from a large cohort epidemiologic study focus on the oldest old the SONIC study. (2015)
  • Author(s): Gondo, Y., Ishizaki, T., Arai, Y., Masui, Y., Ikebe, K., Kamide, K.
  • Organizer: 第57回日本老年医学会学術集会
  • Place of Presentation: パシフィコ横浜（神奈川県・横浜市）
  • Year and Date: 2015-06-13
  • Invited
• [Presentation] Shift of Psychological Adaption Mechanism from Young-old to Oldest-old. (2014)
  • Author(s): Gondo Y, Mausi Y, Nakagawa T.
  • Organizer: Gerontology Society of America
  • Place of Presentation: Washington
  • Year and Date: 2014-11-05 – 2014-11-09
• [Presentation] Age verification of the longest lived men in the world (2014)
  • Author(s): Gondo Y, Saito Y, & Hirose N
  • Organizer: Supercentenarian Workshop
  • Place of Presentation: Paris
  • Year and Date: 2014-09-08 – 2014-09-09
  • Invited
• [Book] よくわかる高齢者心理学 (2016)
  • Author(s): 佐藤眞一,権藤恭之
  • Total Pages: 204
  • Publisher: ミネルヴァ書房
• [Book] アンチエイジング医学の基礎と臨床 (2015)
  • Author(s): 権藤恭之
  • Total Pages: 447
  • Publisher: メジカルビュー社
• [Book] 老化の生物学 (2014)
  • Author(s): 広瀬信義、新井康通、権藤恭之
  • Total Pages: 351
  • Publisher: 化学同人
• [Remarks] 健康長寿研究ＳＯＮＩＣ