| Project/Area Number |
26340048
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Environmental impact assessment
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| Research Institution | Kanazawa University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
神林 康弘 金沢大学, 医学系, 講師 (20345630)
中村 裕之 金沢大学, 医学系, 教授 (30231476)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 大気粉塵 / 重金属 / 多環芳香族炭化水素類 / 慢性咳嗽 / 咳 / PM2.5 / IgE / 気管支喘息 / 金属 / 微小粒子状物質（PM2.5） / 総浮遊粒子状物質（TSP） / 多環芳香族炭化水素類（PAH） / 遷移金属 / 眼のかゆみ / 一般化推定方程式 / 大気汚染 / アレルギー |
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| Outline of Final Research Achievements |
The health effect of ambient dust including Asian dust and PM2.5 becomes a social issue. In this study, we showed that heavy metals contained in ambient dust were associated with aggravation of symptoms (itchy eye, cough) of adult chronic cough (bronchial asthma, cough variant asthma, atopic cough) patients. The aggravation of symptoms by heavy metals was stronger in patients whose serum IgE level were low. It was suggested that the effect of heavy metals on symptoms of chronic cough patients is stronger in patients whose allergy symptoms were weak.
Constituent of heavy metals was different between total suspended particulate and PM2.5. Especially, the concentrations of heavy metals contained in total suspended particulate became higher, but the concentrations of some heavy metals contained in PM2.5 were not changed in Asian dust days. When the health effect of particulate matters is considered, it is important to take account of their constituent.
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