• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Effect to an immune cell of new soy isoflavone for the purpose of the metabolic syndrome prevention

Research Project

Project/Area Number 26350124
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Eating habits
Research InstitutionThe University of Tokushima

Principal Investigator

SHUTO Emi  徳島大学, 大学院医歯薬学研究部(医学系), 講師 (10512121)

Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywordsメタボリックシンドローム / 慢性炎症 / 大豆イソフラボン / イソフラボン
Outline of Final Research Achievements

Because it was reported that the T cell which was an immune cell controlled the basic condition of a patient, and the concept that various lifestyle diseases produced from chronic inflammation attracted attention of onset mechanism of the metabolic syndrome, I did it with the chronic inflammation target through a T cell concerned with the onset of the metabolic syndrome and tried that I elucidated onset mechanism of new metabolic syndrome.
After giving it, and examining Equol using a diet induced obesity mouse by the Western food of 45% of lipid energy ratios, I found that the differentiation polarity of the macrophage in the epididymis fat become the M2 predominance, and improve an insulin signal affected by a high-fat diet.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report

Research Products

(10 results)

All 2016 2015

All Journal Article Presentation

  • [Journal Article] Excessive dietary phosphorus intake impairs endothelial function in young healthy men: a time- and dose-dependent study2015

    • Author(s)
      Nishi T, Shuto E, Ogawa M, Ohya M, Nakanishi M, Masuda M, Katsumoto M, Yamanaka-Okumura H, Sakai T, Takeda E, Sakaue H, Taketani Y.
    • Journal Title

      J. Med. Invest.

      Volume: 62 Issue: 3.4 Pages: 167-172

    • DOI

      10.2152/jmi.62.167

    • NAID

      130005099149

    • ISSN
      1343-1420, 1349-6867
    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Vitamin A Deficiency Impairs Induction of Oral Tolerance in Mice2015

    • Author(s)
      Nakamoto A, Shuto E, Tsutsumi R, Nakamoto M, Nii Y, Sakai T.
    • Journal Title

      J Nutr Sci Vitaminol

      Volume: 61 Issue: 2 Pages: 147-153

    • DOI

      10.3177/jnsv.61.147

    • NAID

      130005074125

    • ISSN
      0301-4800, 1881-7742
    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Dietary Ribonucleic Acid Suppresses Inflammation of Adipose Tissue and Improves Glucose Intolerance That Is Mediated by Immune Cells in C57BL/6 Mice Fed a High-Fat Diet2015

    • Author(s)
      Sakai T, Taki T, Nakamoto A, Tazaki S, Arakawa M, Nakamoto M, Tsutsumi R, Shuto E.
    • Journal Title

      J Nutr Sci Vitaminol

      Volume: 61 Issue: 1 Pages: 73-78

    • DOI

      10.3177/jnsv.61.73

    • NAID

      130005070836

    • ISSN
      0301-4800, 1881-7742
    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] 徳島県男性勤労者の大豆発酵食品摂取は血清IL-6濃度を低下させる2016

    • Author(s)
      楊曉琳、中本真理子、酒井徹、首藤恵泉、篠原尚子、秦明子、南川貴子、田村綾子、市原多香子、桑村由美、船木真理
    • Organizer
      第63回日本栄養改善学会学術総会
    • Place of Presentation
      リンクステーションホール青森 青森県青森市
    • Year and Date
      2016-09-07
    • Related Report
      2016 Annual Research Report
  • [Presentation] スダチチンの免疫調節作用-卵白アルブミン免疫マウスモデルでの検討-2016

    • Author(s)
      三谷麻実、中本真理子、首藤恵泉、酒井徹
    • Organizer
      第63回日本栄養改善学会学術総会
    • Place of Presentation
      リンクステーションホール青森 青森県青森市
    • Year and Date
      2016-09-07
    • Related Report
      2016 Annual Research Report
  • [Presentation] 食餌誘導性肥満マウスにおけるエクオールの効果2016

    • Author(s)
      國松真由香、首藤 恵泉、三谷 麻実、中本真理子、酒井徹
    • Organizer
      第70回日本栄養食糧学会
    • Place of Presentation
      神戸ポートピアホテル 兵庫県神戸市
    • Year and Date
      2016-05-13
    • Related Report
      2016 Annual Research Report
  • [Presentation] 徳島県勤労者における大豆製品摂取と炎症マーカーとの関連2016

    • Author(s)
      楊曉琳、中本真理子、酒井徹、首藤惠泉、篠原尚子、秦明子、安藝菜奈子、小杉知里、四釜洋介、坂東由記子、南川貴子、市原多香子、田村綾子、桑村由美、船木真理
    • Organizer
      第70回日本栄養食糧学会
    • Place of Presentation
      神戸ポートピアホテル 兵庫県神戸市
    • Year and Date
      2016-05-13
    • Related Report
      2016 Annual Research Report
  • [Presentation] 徳島県勤労者のイソフラボン摂取量とアレル2016

    • Author(s)
      中本真理子、酒井徹、首藤恵泉、秦明子、安藝菜奈子、小杉知里、四釜洋介、坂東由記子、南川貴子、市原多香子、田村綾子、桑村由美、船木真理
    • Organizer
      第70回日本栄養食糧学会
    • Place of Presentation
      神戸ポートピアホテル 兵庫県神戸市
    • Year and Date
      2016-05-13
    • Related Report
      2016 Annual Research Report
  • [Presentation] スダチチンの免疫調節作用-卵白アルブミン免疫マウスモデルでの検討-2016

    • Author(s)
      三谷麻実、中本真理子、首藤恵泉、酒井徹
    • Organizer
      第70回日本栄養食糧学会
    • Place of Presentation
      神戸ポートピアホテル 兵庫県神戸市
    • Year and Date
      2016-05-13
    • Related Report
      2016 Annual Research Report
  • [Presentation] 食餌誘導性肥満マウスにおけるエクオールの効果2015

    • Author(s)
      首藤恵泉
    • Organizer
      第62回日本栄養改善学会学術総会
    • Place of Presentation
      福岡国際会議場(福岡県福岡市)
    • Year and Date
      2015-09-24
    • Related Report
      2015 Research-status Report

URL: 

Published: 2014-04-04   Modified: 2018-03-22  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi