Basic study of a measurement of the autonomic nerve balance by the food intake and its food function evaluation
| Project/Area Number |
26350170
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Eating habits
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| Research Institution | Kyushu Nutrition Welfare University |
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Principal Investigator |
KITA Taizo 九州栄養福祉大学, 食物栄養学部, 教授 (50153086)
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| Co-Investigator(Kenkyū-buntansha) |
柳原 延章 産業医科大学, 名誉教授、学長等, 名誉教授 (80140896)
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| Research Collaborator |
SATO Noriaki 産業医科大学, 教育研究支援施設, 助教 (40225983)
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| Project Period (FY) |
2014-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | 自律神経バランス / テアニン / 計算負荷ストレス / ウェアラブルバイオセンサ / カテコールアミン / IkarisosideA / 松抽出物 / ウシ副腎髄質細胞 / 計算負荷 / 緑茶 / ストレス / カテーコールアミン / 松節抽出物 / ウエアラブルバイオセンサ / フラボノイド |
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| Outline of Final Research Achievements |
In this study, we conducted autonomic nerve balance （ANB）measurement by food intake and basic research on its food function evaluation. ANB was measured by power spectral analysis of heart rate variability using a standard hexagonal radar chart. In the placebo group, there was a significant increase in sympathetic nervous system activity induced by acute arithmetic task, but little change in the theanine group. Furthermore, similar results were obtained by simplifying ANB measurement using a wearable biological sensor. The present study demonstrated that the assay system of ANB detects the increase in sympathetic nervous system activity induced by acute arithmetic stress, which was attenuated by theanine in healthy female volunteers. In addition, it was revealed that flavonoid Ikarisoside A and pine extract SJ-2 inhibited secretion and synthesis of catecholamine using bovine adrenal medullary cells in primary culture system.
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Report
(5 results)
Research Products
(50 results)
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[Journal Article] Inhibitory effects of pine nodule extract and its component, SJ-2, on acetylcholine-induced catecholamine secretion and synthesis in bovine adrenal medullary cells.2017
Author(s)
Li X, Horishita T, Toyohira Y, Shao H, Bai J, Bo H, Song X, Ishikane S, Yoshinaga Y, Satoh N, Tsutsui M, Yanagihara N.
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Journal Title
J Pharmacol Sci
Volume: 133
Pages: 268-75
NAID
Related Report
Peer Reviewed
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[Journal Article] Inhibitory effects of pine nodule extract and its component, SJ-2, on acetylcholine-induced catecholamine secretion and synthesis in bovine adrenal medullary cells2017
Author(s)
2.Li X, Horishita T, Toyohira Y, Shao H, Bai J, Bo H, Song X, Ishikane S, Yoshinaga Y, Satoh N, Tsutsui M, Yanagihara N
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Journal Title
J Pharmacol Sci.
Volume: 印刷中
Pages: 268-275
DOI
NAID
Related Report
Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
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[Journal Article] Ikarisoside A inhibits acetylcholine-induced catecholamine secretion and synthesis by suppressing nicotinic acetylcholine receptor-ion channels in cultured bovine adrenal medullary cells.2015
Author(s)
Li X, Toyohira Y., Horisita T., Satoh N., Takahashi K., Zhang H., Iinuma M.,Yoshinaga Y., Ueno S., Tsutsui M., Sata T., Yanagihara N.
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Journal Title
Naunyn Schmiedebergs Arch Pharmacol.
Volume: 388
Pages: 1259-1269
DOI
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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[Journal Article] Stimulatory effect of nobiletin, a citrus polymethoxy flavone, on catecholamine synthesis through Ser19 and Ser40 phosphorylation of tyrosine hydroxylase in cultured bovine adrenal medullary cells.2014
Author(s)
Zhang H., Yanagihara N., Toyohira Y., Takahashi K., Inagaki H., Satoh N., Xiaoja L., Goa X., Tsutsui M., Takahashi K.
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Journal Title
Naunyn-Schmiedeberg’s Arch of Pharmacol.
Volume: 387
Pages: 15-22
Related Report
Peer Reviewed / Open Access
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