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Development of educational materials to assist students with understanding cellular and molecular immunity

Research Project

Project/Area Number 26350225
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Science education
Research InstitutionSaitama University

Principal Investigator

HIBINO Taku  埼玉大学, 教育学部, 准教授 (60513835)

Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords高等学校生物基礎・生物 / Toll様受容体(TLR) / 教材開発 / 教材実践 / 免疫 / トル様受容体 / 自然免疫
Outline of Final Research Achievements

Toll-like receptors (TLRs) are protein sensors located on immune cells, which function as pathogen recognition by the innate immune system. I developed TLR Card Game as an educational material to assist students with understanding the mechanism of the innate pathogen recognition. The TLR Card Game was carried out in an extracurricular class of a high school in Saitama City. The effectiveness of the material was assessed by questionnaires for 30 students. All the students got interested in the game and its immunology. Next, I developed An Adventure to Comprehend Immunity, which is a board game for connecting a desktop learning of immunology with an everyday occurrence and the world. Finally, the embryos of three echinoids were tested if they are suitable to observe in vivo phagocytosis. A swift phagocytosis was occurred in the blastocoel of the embryo of Clypeaster japonicus, thus this species is better for educational experiment.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report

Research Products

(12 results)

All 2017 2016 2015 Other

All Int'l Joint Research (1 results) Journal Article (4 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 2 results,  Open Access: 4 results,  Acknowledgement Compliant: 1 results) Presentation (4 results) Book (2 results) Remarks (1 results)

  • [Int'l Joint Research] Sunnybrook Health Science Centre(カナダ)

    • Related Report
      2016 Annual Research Report
  • [Journal Article] Perturbation of gut bacteria induces a coordinated cellular immune response in the purple sea urchin larva.2016

    • Author(s)
      Ho EC, Buckley KM, Schrankel CS, Schuh NW, Hibino T, Solek CM, Bae K, Wang G, Rast JP
    • Journal Title

      Immunology & Cell Biology

      Volume: 94(9) Pages: 861-874

    • DOI

      10.1038/icb.2016.51

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] 自然免疫の異物識別機構への理解を促すTLRカードゲームの開発2016

    • Author(s)
      日比野拓
    • Journal Title

      埼玉大学紀要 教育学部

      Volume: 65(2) Pages: 261-270

    • Related Report
      2016 Annual Research Report
    • Open Access / Acknowledgement Compliant
  • [Journal Article] 実験・観察の活動を取り入れた生活科授業-教科内容学模索の取り組み-2016

    • Author(s)
      鶴ヶ谷柊子、日比野拓
    • Journal Title

      埼玉大学教育実践総合センター紀要

      Volume: 15 Pages: 135-140

    • NAID

      120006388173

    • Related Report
      2015 Research-status Report
    • Open Access
  • [Journal Article] Early stalked stages in ontogeny of the living isocrinid sea lily Metacrinus rotundus2016

    • Author(s)
      Amemiya, S., Omori, A., Tsurugaya, T., Hibino, T., Yamaguchi, M., Kuraishi, R., Kiyomoto, M., and Minokawa, T.
    • Journal Title

      Acta Zoologica

      Volume: in press Pages: 102-116

    • DOI

      10.1111/azo.12109

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] 地域に密着した自然環境調査と環境保全教育―宝蔵寺沼の水生動物相調査を事例として2017

    • Author(s)
      吉田竜矢、田端雄樹、矢辺徹、日比野拓
    • Organizer
      日本生物教育学会第101回全国大会
    • Place of Presentation
      東京学芸大学(東京都小金井市)
    • Year and Date
      2017-01-08
    • Related Report
      2016 Annual Research Report
  • [Presentation] ウニ胚内で起こる貪食作用の比較発生学的解析2016

    • Author(s)
      日比野拓
    • Organizer
      日本比較免疫学会第28回学術集会
    • Place of Presentation
      東京医科歯科大学(東京都文京区)
    • Year and Date
      2016-08-18
    • Related Report
      2016 Annual Research Report
  • [Presentation] トル様受容体について楽しく学ぶ「TLRカードゲーム」の開発2016

    • Author(s)
      日比野拓
    • Organizer
      日本生物教育学会 第100回全国大会
    • Place of Presentation
      東京理科大学神楽坂キャンパス(東京都新宿区)
    • Year and Date
      2016-01-11
    • Related Report
      2015 Research-status Report
  • [Presentation] タコノマクラ胚発生における貪食開始の異時性2015

    • Author(s)
      日比野拓
    • Organizer
      日本比較免疫学会 第27回学術集会
    • Place of Presentation
      小浜市働く婦人の家(福井県小浜市)
    • Year and Date
      2015-08-21
    • Related Report
      2015 Research-status Report
  • [Book] ぼくらは「生物学」のおかげで生きている (素晴らしきサイエンス)2016

    • Author(s)
      金子康子、日比野拓
    • Total Pages
      232
    • Publisher
      実務教育出版
    • Related Report
      2015 Research-status Report
  • [Book] TLRカードゲーム2015

    • Author(s)
      日比野 拓
    • Publisher
      萬印堂
    • Related Report
      2014 Research-status Report
  • [Remarks] 埼玉大学教育学部 自然科学講座理科分野 日比野研究室

    • URL

      https://sites.google.com/view/hibino-lab/

    • Related Report
      2016 Annual Research Report

URL: 

Published: 2014-04-04   Modified: 2018-03-22  

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