Preparation of Novel Biodegradable Biomaterials using High-pressure
| Project/Area Number |
26350527
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Biomedical engineering/Biomaterial science and engineering
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| Research Institution | Kagoshima University |
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Principal Investigator |
Kazuya YAMAMOTO 鹿児島大学, 理工学域工学系, 准教授 (40347084)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 高圧力 / 開環重合 / ナノ粒子 / 低分子量化 / ナノ材料 / キチン |
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| Outline of Final Research Achievements |
We examined the development of novel biodegradable biomaterials using hight-pressure. First, the acid-catalysed ring-opening polymerization of gamma-butyrolactone (gamma-BL) was carried out in the presence of methanol as an initiator and trifluoromethanesulfonic acid as a catalyst. As the result, the monomer conversions increased with increasing pressures, indicating that high pressure conditions strongly affected the polymerization manner. Next, we performed the preparation of chitin nanoparticles by regeneration from a chitin/1-allyl-3-methylimidazolium bromide solution through high-pressure process. The morphology of nanoparticles was seen in the SEM image of the sample from the resulting dispersion.
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Report
(4 results)
Research Products
(17 results)
