Effect of ultrasonic irradiation on bacterial biofilms
| Project/Area Number |
26350543
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Medical systems
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| Research Institution | Jichi Medical University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
藤井 康友 京都大学, 医学研究科, 教授 (00337338)
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| Project Period (FY) |
2014-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Keywords | 超音波 / 細菌 / バイオフィルム / 表皮ブドウ球菌 / カテーテル関連血流感染症 / 中心静脈カテーテル / 検査 / 治療 |
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| Outline of Final Research Achievements |
Ultrasonic irradiation (US) can decrease the amount of Staphylococcus epidermidis (S. epidermidis) biofilm when the duration of US irradiation is sufficiently long even if the acoustic intensity is low.
In addition, US irradiation can inhibit the formation of S.epidermidis biofilm. And the inhibitory effect of US irradiation at the early stage can reduced the biofilm formation even if the duration time of US irradiation was short.The inhibitory effect of duplicated irradiation on biofilm effect had nearly twice as high as single irradiation, however, the single irradiation at early stage can also reduce the biofilm formation by 17.9 %.
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Report
(5 results)
Research Products
(9 results)
