• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Effects of rehabilitative approaches on changes neurotransmitter levels and neurotrophic factor expression after brain injury in rats

Research Project

Project/Area Number 26350575
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Rehabilitation science/Welfare engineering
Research InstitutionKagoshima University

Principal Investigator

OHWATASHI AKIHIKO  鹿児島大学, 医歯学域医学系, 准教授 (30295282)

Co-Investigator(Kenkyū-buntansha) 池田 聡  北海道大学, 大学病院, 准教授 (00343369)
吉田 輝  鹿児島大学, 医歯学域附属病院, 講師 (40347109)
Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywordsマイクロダイアリシス / 神経伝達物質 / 脳の可塑性 / 運動療法 / 機能回復 / 神経栄養因子
Outline of Final Research Achievements

Extracellular concentrations of monoamines were investigated in the striatum, hippocampus, primary cortex and hindlimb region using microdialysis technique. We confirmed serotonin, norepinephrine and dopamine levels on those region of rat brain in daily living. Rats underwent photochemical infarction, and monoamine levels were investigated in the hippocampus during treadmill running on 3 days, 1 week and 2 weeks after infarction. Serotonin and norepinephrine levels increased remarkably during treadmill running on 2 weeks after infarction. Future study has to determine another region concerning functional recovery, and investigate repeatedly.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (17 results)

All 2016 2015 2014

All Journal Article (7 results) (of which Peer Reviewed: 6 results,  Open Access: 2 results) Presentation (9 results) (of which Int'l Joint Research: 1 results) Book (1 results)

  • [Journal Article] 二次予防事業の不参加者特性と介護予防マシンの開発コンセプト-身体機能の向上と参加意欲を両立させるマシンの開発要件-2016

    • Author(s)
      山田誠,石原田秀一,大渡昭彦
    • Journal Title

      鹿児島大学法文学部紀要「経済学論集」

      Volume: 86 Pages: 39-63

    • NAID

      120005728621

    • Related Report
      2016 Annual Research Report 2015 Research-status Report
  • [Journal Article] 虚弱高齢者において生活空間と身体機能が転倒リスクに与える影響2016

    • Author(s)
      和田隆,小野恵,外西正博,有川順子,新保直規,木山良二,大渡昭彦,大重匡,吉元洋一
    • Journal Title

      理学療法科学

      Volume: 31(1) Pages: 81-85

    • NAID

      130005132361

    • Related Report
      2016 Annual Research Report 2015 Research-status Report
    • Peer Reviewed
  • [Journal Article] The Effects of Lateral Wedge Insole on Knee and Ankle Joint During Slope Walking.2015

    • Author(s)
      Uto Y, Maeda T, Kiyama R, Kawada M, Tokunaga K, Ohwatashi A, Fukudome K, Ohshige T, Yoshimoto Y, Yone K.
    • Journal Title

      J Appl Biomech.

      Volume: 31(6) Pages: 476-483

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Journal Article] The Varying Effects of Warm-water Bathing Therapies: Partial Bathing Decreases Exercise Intensity to Levels Similar to Full-body Bathing.2015

    • Author(s)
      Tadasu Ohshige, Akihiko Ohwatashi,Ryoji Kiyama.
    • Journal Title

      J Phys Ther Sci.

      Volume: 27(11) Pages: 3373-3375

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Journal Article] Hyperthermic effects of hand bathing: benefits of incorporating finger flexion-extension exercise.2015

    • Author(s)
      Tadasu Ohshige, Akihiko Ohwatashi,Ryoji Kiyama, Hiroaki Nishi, Akihisa Takamori.
    • Journal Title

      J Phys Ther Sci.

      Volume: 27(12) Pages: 3779-3782

    • NAID

      130005115956

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Journal Article] Temperature changes caused by the difference in the distance between the ultrasound transducer and bone during 1 MHz and 3 MHz continuous ultrasound: a phantom study2015

    • Author(s)
      Akihiko Ohwatashi, Satoshi Ikeda, Katsuhiro Harada, Yurie Kamikawa, Akira Yoshida, Kazuhiro Inoue, Nobuhiko Yanagida, Kiyohiro Fukudome, Ryoji Kiyama, Tadasu Ohshige, Tetsuo Maeda.
    • Journal Title

      Journal of Physical Therapy Science

      Volume: 27 Issue: 1 Pages: 205-208

    • DOI

      10.1589/jpts.27.205

    • NAID

      130004835111

    • ISSN
      0915-5287, 2187-5626
    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] The effect of force sensation on the ability to control muscle force during fatigue condition.2014

    • Author(s)
      Ryoji Kiyama, Masayuki Kawada, Ken Tokunaga, Akihiko Ohwatashi, Kiyohiro Fukudome, Kazunori Yone, Yoichi Yoshimoto, Tadasu Ohshige and Tetsuo Maeda.
    • Journal Title

      Isokinetics and Exercise Science

      Volume: 22 Issue: 4 Pages: 287-293

    • DOI

      10.3233/ies-140550

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] 体幹の加速度・角速度を指標とした人工膝関節全置換術による歩容変化の分析2016

    • Author(s)
      才田剛志,木山良二,大渡昭彦,貴島芳文,前田哲男
    • Organizer
      第51回日本理学療法学術大会
    • Place of Presentation
      札幌コンベンションセンター(北海道札幌市)
    • Year and Date
      2016-05-27
    • Related Report
      2016 Annual Research Report
  • [Presentation] 斜面歩行における関節負荷の検討2015

    • Author(s)
      川田将之,木山良二,大渡昭彦,大重匡,前田哲男
    • Organizer
      第50回日本理学療法学術大会
    • Place of Presentation
      東京国際フォーラム(東京都)
    • Year and Date
      2015-06-05
    • Related Report
      2015 Research-status Report
  • [Presentation] 温浴(全身浴・前腕浴・下腿浴)の重心動揺効果とウォーミングアップ効果について2015

    • Author(s)
      大重匡,渋谷翔大,宮崎 宣丞,野田 詩織,大渡昭彦,木山 良二
    • Organizer
      第50回日本理学療法学術大会
    • Place of Presentation
      東京国際フォーラム(東京都)
    • Year and Date
      2015-06-05
    • Related Report
      2015 Research-status Report
  • [Presentation] Efect of rotator cuff tears on joint reaction force and muscle force: muscloskeletal model simulation.2015

    • Author(s)
      Kiyama R., Kakoi H., Nojima T., Kisanuki I., Yamano T., Ohwatashi A., Maeda T.
    • Organizer
      World Confederation for Physical Therapy Congress 2015
    • Place of Presentation
      Singapore (Singapore)
    • Year and Date
      2015-05-01
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] 光感受性色素を用いた霊長類脳梗塞片麻痺モデルの作成とその行動観察研究2014

    • Author(s)
      原田雄大,池田聡,大渡昭彦,上川百合恵,根路銘周子,山下真紀,吉田輝,白橋いずみ
    • Organizer
      第551回日本リハビリテーション医学会学術集会
    • Place of Presentation
      名古屋(名古屋国際会議場)
    • Year and Date
      2014-06-06
    • Related Report
      2014 Research-status Report
  • [Presentation] 筋力増強の分子生物学的検討と脳梗塞モデルを用いた機能回復の検討(シンポジウム)2014

    • Author(s)
      池田聡,上川百合恵,原田雄大,吉田輝,大渡昭彦
    • Organizer
      第51回日本リハビリテーション医学会学術集会
    • Place of Presentation
      名古屋(名古屋国際会議場)
    • Year and Date
      2014-06-05
    • Related Report
      2014 Research-status Report
  • [Presentation] トレーニングの有無がトレッドミル運動による線条体と海馬のモノアミン細胞外濃度変化に与える影響2014

    • Author(s)
      ・大渡昭彦, 吉田輝, 池田聡, 原田雄大, 大重匡, 木山良二, 前田哲男
    • Organizer
      第49回日本理学療法学術大会
    • Place of Presentation
      横浜(パシフィコ横浜)
    • Year and Date
      2014-05-09
    • Related Report
      2014 Research-status Report
  • [Presentation] 歩行時の足角の変化が外側ウェッジの効果に及ぼす影響2014

    • Author(s)
      徳永健, 木山良二, 大渡昭彦, 前田哲男
    • Organizer
      第49回日本理学療法学術大会
    • Place of Presentation
      横浜(パシフィコ横浜)
    • Year and Date
      2014-05-09
    • Related Report
      2014 Research-status Report
  • [Presentation] 方向転換時の足部の運動学的分析と性差による影響2014

    • Author(s)
      上野友愛, 木山良二, 大渡昭彦, 前田哲男
    • Organizer
      第49回日本理学療法学術大会
    • Place of Presentation
      横浜(パシフィコ横浜)
    • Year and Date
      2014-05-09
    • Related Report
      2014 Research-status Report
  • [Book] 解いてなっとく使えるバイオメカニクス2015

    • Author(s)
      前田哲男,木山良二,大渡昭彦
    • Total Pages
      200
    • Publisher
      医学書院
    • Related Report
      2015 Research-status Report

URL: 

Published: 2014-04-04   Modified: 2018-03-22  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi