| Project/Area Number |
26350862
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Applied health science
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| Research Institution | Institute of Wellness and Ecological Sciences (Global Research Center for Applied System Science) |
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Principal Investigator |
SO MIRAI 有限会社自然医科学研究所(実証システム国際研究センター), 実証システム国際研究センター, 研究員 (00327636)
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| Co-Investigator(Kenkyū-buntansha) |
関沢 洋一 独立行政法人経済産業研究所, 研究グループ, 上席研究員 (60444098)
前川 浩子 金沢学院大学, 文学部, 准教授 (10434474)
山口 芳香 有限会社自然医科学研究所(実証システム国際研究センター), 実証システム国際研究センター, 代表 (00420737)
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| Co-Investigator(Renkei-kenkyūsha) |
WATANABE Norio 京都大学, 医学(系)研究科(研究院)・その他部局等, 准教授 (20464563)
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| Research Collaborator |
YAMAGUCHI Sosei
SADO Mitsuhiro
TAKEBAYASHI Yoshitake
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥260,000 (Direct Cost: ¥200,000、Indirect Cost: ¥60,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
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| Keywords | Internet CBT / インターネット認知行動療法 / CBT / ICBT / CCBT / RCT / 認知行動療法 / 強化学習 / cost effectiveness |
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| Outline of Final Research Achievements |
We evaluated the effectiveness of self-help internet-based cognitive behavioural therapy (iCBT) over ７ weeks among Japanese workers with depression (RCT). Also, we evaluated in parallel whether the weekly 10 minutes’ pair-work exercise by “talking to others” of what they learned through experiencing self-help iCBT enhance the effectiveness of standalone iCBT. The result was the standalone iCBT group showed a significant moderate-to-large improvement of depression, with an effect size of Hedge’s g = 0.65, compared to the waitlist group. On the other hand, there was no significant difference between the pair-work iCBT and the waitlist. There were different opinions on the pros and cons. Moreover, it was demonstrated that there was a marginally significant positive association between the number of pair-work exercises and the antidepressant efficacy only among those with higher anxiety at baseline (p=0.06). Due to the lack of the pair-work efficacy, there was no cost-effectiveness.
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