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Proteome analysis of toxoplasmic retinochoroiditis-a quest of biomarker

Research Project

Project/Area Number 26460505
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Parasitology (including sanitary zoology)
Research InstitutionChiba University

Principal Investigator

Norose Kazumi  千葉大学, 大学院医学研究院, 准教授 (30156244)

Co-Investigator(Kenkyū-buntansha) 佐藤 守  千葉大学, 医学部附属病院, 特任准教授 (20401002)
日和佐 隆樹  千葉大学, 大学院医学研究院, 准教授 (30260251)
Project Period (FY) 2014-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2016: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2014: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Keywordsトキソプラズマ / トキソプラズマ性網脈絡膜炎 / プロテオーム解析 / バイマーカー / バイオマーカー / プロテオソーム / 前房水 / 硝子体液 / プロテオーム
Outline of Final Research Achievements

We established successfully a murine model of ocular toxoplasmosis (OT) infected perorally. Observations with fundus camera and fluorescein angiogram revealed that this model resembled with the human OT. The levels of cytokines and chemokines in aqueous humor, cerebrospinal fluid and serum were investigated and some molecules were identified to increase significantly after infection. In addition, some specific proteins were identified to either increase or decrease 2-fold after infection by the analysis on mouse retina using two-dimensional electrophoresis and mass spectrometry. It is suggestive that these molecules may play pivotal roles in the pathogenesis of OT and that analyzing these molecules is helpful to diagnose human OT during its early stage.

Report

(4 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (95 results)

All 2017 2016 2015 2014 Other

All Journal Article (45 results) (of which Int'l Joint Research: 12 results,  Peer Reviewed: 45 results,  Open Access: 32 results,  Acknowledgement Compliant: 13 results) Presentation (44 results) (of which Int'l Joint Research: 2 results,  Invited: 3 results) Book (2 results) Remarks (2 results) Patent(Industrial Property Rights) (2 results)

  • [Journal Article] Cutaneous Rosai-Dorfman disease associated with uveitis2017

    • Author(s)
      Fukumoto T, Oka M, Masaki T, Sakaguchi M, Fukunaga A, Norose K, Sarayama Y, Imai H, Nishigori C
    • Journal Title

      Eur J Dermatol

      Volume: 27 Issue: 1 Pages: 85-86

    • DOI

      10.1684/ejd.2016.2885

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Circulating anti-coatomer protein complex subunit epsilon (COPE) autoantibodies as a potential biomarker for cardio- and cerebro-vascular events in patients with obstructive sleep apnea2017

    • Author(s)
      Matsumura T, Terada J, Kinoshita T, Sakurai Y, Yahaba M, Ema R, Amata A, Sakao S, Nagashima K, Tatsumi K, Hiwasa T
    • Journal Title

      J Clin Sleep Med

      Volume: 13 Issue: 03 Pages: 393-400

    • DOI

      10.5664/jcsm.6488

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] The pluripotent stem-cell marker alkaline phosphatase is highly expressed in refractory glioblastoma with DNA hypomethylation.2017

    • Author(s)
      Iwadate, Y., Suganami, A., Tamura, Y., Matsutani, T., Hirono, S., Shinozaki, N., Hiwasa, T., Takiguchi, M., and Saeki, N.
    • Journal Title

      Neurosurgery

      Volume: 80 Issue: 2 Pages: 248-248

    • DOI

      10.1093/neuros/nyw026

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] An anti-deoxyhypusine synthase antibody as a marker of atherosclerosis-related cerebral infarction, myocardial infarction, diabetes mellitus, and chronic kidney disease2017

    • Author(s)
      Nakamura R, Tomiyoshi G, Shinmen N, Kuroda H, Kudo T, Doi H,, et al
    • Journal Title

      SM Atheroscler J

      Volume: 1 Pages: 1001-1001

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Dioleoyl-phosphatidic acid selectively binds to α-synuclein and strongly induces its aggregation2017

    • Author(s)
      Satoru Mizuno, Hirotaka Sasai, Aiko Kume, Mamoru Satoh, Sayaka Kado, Fumio Sakane
    • Journal Title

      FEBS Letters

      Volume: 591 Issue: 5 Pages: 784-791

    • DOI

      10.1002/1873-3468.12592

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Immune-complex level of cofilin-1 in sera is associated with cancer progression and poor prognosis in pancreatic cancer2017

    • Author(s)
      Satoh M, Takano S, Sogawa K, Noda K, Yoshitomi H, Ishibashi M, Mogushi K, Takizawa H, Otsuka M, Shimizu H, Miyazaki M, Nomura F.
    • Journal Title

      Cancer Sci.

      Volume: 108 Issue: 4 Pages: 795

    • DOI

      10.1111/cas.13181

    • URL

      https://pure.teikyo.jp/en/publications/3c95b981-c055-4b03-860a-96d5756a0ad3

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Enhancing analysis throughput, sensitivity and specificity in LC/ESI-MS/MS assay of plasma 25-hydroxyvitamin D3 by derivatization with triplex DAPTAD isotopologues2017

    • Author(s)
      S. Ogawa, H. Kittaka, A. Nakata, M. Satoh, F. Nomura, T. Higashi
    • Journal Title

      Journal of Pharmaceutical and Biomedical Analysis

      Volume: 136 Pages: 126-133

    • DOI

      10.1016/j.jpba.2016.11.030

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Proteome analysis of hemofilter adsorbates to identify novel substances of sepsis: a pilot study2017

    • Author(s)
      Hashida T, Nakada TA, Satoh M, Tomita K, Kawaguchi R, Nomura F, Oda S.
    • Journal Title

      J Artif Organs

      Volume: 20 Issue: 2 Pages: 132-137

    • DOI

      10.1007/s10047-016-0936-3

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Clinical characteristics and computed tomography findings of pulmonary toxoplasmosis after hematopoietic stem cell transplantation.2016

    • Author(s)
      Sumi M, Norose K, Hikosaka K, Kaiume H, Takeda W, Kirihara T, Kurihara T, Sato K, Ueki T, Hiroshima Y, Kuraishi H, Watanabe M, Kobayashi H.
    • Journal Title

      Int J Hematol

      Volume: 104 Issue: 6 Pages: 729-740

    • DOI

      10.1007/s12185-016-2077-0

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Anti-FIRs (PUF60) auto-antibodies are detected in the sera of early-stage colon cancer patients.2016

    • Author(s)
      Kobayashi S, Hoshino T, Hiwasa T, Satoh M, Rahmutulla B, Tsuchida S, Komukai Y, Tanaka T, Matsubara H, Shimada H, Nomura F, Matsushita K
    • Journal Title

      Oncotarget

      Volume: 7 Issue: 50 Pages: 82493-82503

    • DOI

      10.18632/oncotarget.12696

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Fractionation of gamma-glutamyltransferase in patients with nonalcoholic fatty liver disease and alcoholic liver disease2016

    • Author(s)
      Sueyoshi S, Sawai S, Satoh M, Seimiya M, Sogawa K, Fukumura A, Tsutsumi M, Nomura F
    • Journal Title

      World J Hepatol

      Volume: 8 Issue: 36 Pages: 1610-1616

    • DOI

      10.4254/wjh.v8.i36.1610

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Fibrinogen alpha C chain 5.9 kDa fragment (FIC5.9), a biomarker for various pathological conditions, is produced in post-blood collection by fibrinolysis and coagulation factors2016

    • Author(s)
      Kikuchi W, Nishimura M, Kuga T, Tsuchida S, Saito T, Satoh M, Noda K, Kodera Y, Tomonaga T, Nomura F
    • Journal Title

      Clinical Proteomics

      Volume: 13 Issue: 1 Pages: 27-27

    • DOI

      10.1186/s12014-016-9129-6

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Valosin-containing Protein is a Target of 5'-l Fuligocandin B and Enhances TRAIL Resistance in Cancer Cells2016

    • Author(s)
      Arai, M. A.*; Taguchi, S.; Komatsuzaki, K.; Uchiyama, K.; Masuda, A.; Sampei, M.; Satoh, M.; Kado, S.; Ishibashi, M.*
    • Journal Title

      ChemistryOPEN

      Volume: 5 Issue: 6 Pages: 574-579

    • DOI

      10.1002/open.201600081

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Identification of a novel serum biomarker for pancreatic cancer, C4b-binding protein α-chain (C4BPA) by quantitative proteomic analysis using tandem mass tags2016

    • Author(s)
      Sogawa K, Takano S, Iida F, Satoh M, Tsuchida S, Kawashima Y, Yoshitomi H, Sanda A, Kodera Y, Takizawa H, Mikata R, Ohtsuka M, Shimizu H, Miyazaki M, Yokosuka O, Nomura F.
    • Journal Title

      Br J Cancer.

      Volume: 115 Issue: 8 Pages: 949

    • DOI

      10.1038/bjc.2016.295

    • URL

      https://localhost/en/publications/88e7c93f-30ed-429f-9fd3-64eb9f619cb0

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] A Method for Simultaneous Determination of 25-Hydroxyvitamin D<sub>3</sub> and Its 3-Sulfate in Newborn Plasma by LC/ESI-MS/MS after Derivatization with a Proton-Affinitive Cookson-Type Reagent2016

    • Author(s)
      T. Higashi, M. Yokota, A. Goto, S. Ogawa, K. Komatsu, T. Sugiura, M. Satoh, F. Nomura
    • Journal Title

      Mass Spectrometry

      Volume: 5 Issue: 2 Pages: S0051-S0051

    • DOI

      10.5702/massspectrometry.S0051

    • NAID

      130005263499

    • ISSN
      2186-5116, 2187-137X
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Development and validation of the simultaneous measurement of four vitamin D metabolites in serum by LC-MS/MS for clinical laboratory applications2016

    • Author(s)
      Mamoru Satoh, Takayuki Ishige, Shoujiro Ogawa, Motoi Nishimura, Kazuyuki Matsushita, Tatsuya Higashi, Fumio Nomura
    • Journal Title

      Anal Bioanal Chem

      Volume: 408 Issue: 27 Pages: 7617-7627

    • DOI

      10.1007/s00216-016-9821-4

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Quantitative assessment of the effects of sulfamethoxazole on Toxoplasma gondii loads in susceptible WT C57BL/6 mice as an2016

    • Author(s)
      Belal US, Norose K, Mohamed RM, Sekine S, Nukaga T, Ito K, Abdellatif MZ, Abdelgelil NH, Yano A.
    • Journal Title

      Parasitol Int.

      Volume: 65 Issue: 1 Pages: 1-4

    • DOI

      10.1016/j.parint.2015.09.004

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Forensic study of Schistosoma japonicum eggs found in an autopsy case.2016

    • Author(s)
      Motomura A, Norose K, Hoshioka Y, Torimitsu S, Chiba F, Makino Y, Inokuchi G, Yajima D, Ohta N, Kumagai T, Iwase H
    • Journal Title

      Parasitol Int

      Volume: 65(3) Issue: 3 Pages: 285-287

    • DOI

      10.1016/j.parint.2016.02.008

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Elevated adiponectin antibody levels in sera of patients with atherosclerosis-related coronary artery disease, cerebral infarction, and diabetes mellitus.2016

    • Author(s)
      Hiwasa T, Zhang XM, Kimura R, Ohno M, Chen PM, Nishi E, Ono K, Kimura T, Kamitsukasa I, Wada T, Aotsuka S, Mine S, Takizawa H, Kashiwado K, Takemoto M, Kobayashi K, Kawamura H, Ishibashi R, Yokote K, Nakamura R, Tomiyoshi G, Shinmen N, Kuroda H
    • Journal Title

      J Circ Biomark

      Volume: 5 Pages: 8-8

    • DOI

      10.5772/63218

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Polymerase Chain Reaction: A Better Method for Diagnosing Chronic Schistosoma mansoni Infections.2015

    • Author(s)
      Abdel-Hafeez EH, Mohamed RM, Belal US, Abdel-Raheem EM, Naoi K, Norose K
    • Journal Title

      Trop Med Health

      Volume: 43(4) Issue: 4 Pages: 205-209

    • DOI

      10.2149/tmh.2015-22

    • NAID

      130005130391

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Identification of stroke-associated-antigens via screening of recombinant proteins from the human expression cDNA library (SEREX)2015

    • Author(s)
      Machida, T., Kubota, M., Kobayashi, E., Iwadate, Y., Saeki, N., Yamaura, A., Nomura, F., Takiguchi, M., Hiwasa, T.
    • Journal Title

      Journal of Translational Medicine

      Volume: 13 Issue: 1 Pages: 71-71

    • DOI

      10.1186/s12967-015-0393-4

    • Related Report
      2015 Research-status Report 2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Identification of Cerebral Infarction-Specific Antibody Markers from Autoantibodies Detected in Patients with Systemic Lupus Erythematosus.2015

    • Author(s)
      Goto K, Sugiyama T, Matsumura R, Zhang XM, Kimura R, Taira A, Arita E, Iwase K, Kobayashi E, Iwadate Y, Saeki N, Mori M, Uzawa A, Muto M, Kuwabara S, Takemoto M, Kobayashi K, Kawamura H, Ishibashi R, Sakurai K, et al
    • Journal Title

      J. Mol. Biomark. Diagnos.

      Volume: 6 Issue: 02 Pages: 2-2

    • DOI

      10.4172/2155-9929.1000219

    • Related Report
      2015 Research-status Report 2014 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Elevated serum antibody levels against cyclin L2 in patients with esophageal squamous cell carcinoma.2015

    • Author(s)
      Shimada H, Ito M, Kagaya A, Shiratori T, Kuboshima M, Suzuki M, Liu TL, Nabeya Y, Matsubara H, Matsushita K, Nomura F, Takiguchi M, Hiwasa T
    • Journal Title

      J Cancer Sci Ther

      Volume: 7(2) Issue: 02 Pages: 60-66

    • DOI

      10.4172/1948-5956.1000326

    • Related Report
      2015 Research-status Report 2014 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Up-regulation of growth-inhibitory or tumor suppressive genes by overexpression of C/EBPα or C/EBPβ in ras-transformed NIH3T3 cells.2015

    • Author(s)
      Kuroiwa N, Iwase K, Morii S, Takiguchi M, Hiwasa T
    • Journal Title

      Integr Mol Med

      Volume: 2(2): Pages: 150-157

    • Related Report
      2015 Research-status Report 2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Novel serum autoantibodies against talin1 in multiple sclerosis: Possible pathogenetic roles of the antibodies2015

    • Author(s)
      Muto M, Mori M, Hiwasa T, Takiguchi M, Iwadate Y, Uzawa A, Uchida T, Masuda H, Sugimoto K, Kuwabara S.
    • Journal Title

      Journal of Neuroimmunology

      Volume: 284 Pages: 30-36

    • DOI

      10.1016/j.jneuroim.2015.05.005

    • NAID

      120007088198

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Identification of the p53-responsive element in the promoter region of the human decorin gene.2015

    • Author(s)
      Hiwasa T, Iwase K, Suichi T, Hino Y, Kimura R, Shinmen N, Takiguchi M
    • Journal Title

      Mol Biol

      Volume: 4 Issue: 01 Pages: 1-1

    • DOI

      10.4172/2168-9547.1000124

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Association of serum antibody levels against TUBB2C with diabetes and cerebral infarction.2015

    • Author(s)
      Hiwasa T, Zhang XM, Kimura R, Machida T, Kitamura K, Yamazoe R, Kunimatsu M, Mine S, Kobayashi E, Iwadate Y, Saeki N, Takemoto M, Kobayashi K, Kawamura H, Ishibashi R, Sakurai K, Fujimoto M, Yokote K, Iwata Y, Nakayama T, Harada J, Kobayashi Y, Ohno M, Chen PM, Nishi E, Yokota M, Kamitsukasa I, et al.
    • Journal Title

      Gratis J Biomed Sci

      Volume: 1(2) Issue: 2 Pages: 49-63

    • DOI

      10.18314/gjbs.v1i2.27

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Role of Evaluating MGMT Status and 1p36 Deletion in radiosurgery-induced anaplastic ependymoma that rapidly and completely resolved by temozolomide alone: Case report and review of the literature.2015

    • Author(s)
      Hirono S, Iwadate Y, Kambe M, Hiwasa T, Takiguchi M, Nakatani Y, Saeki N
    • Journal Title

      J Neurol Surg Rep

      Volume: 76(1) Issue: 01 Pages: e43-e47

    • DOI

      10.1055/s-0034-1396657

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Exogenous expression of FIR demonstrated TP53-independent cell-killing effect and enhanced anti-tumor activity of carbon-ion beams.2015

    • Author(s)
      Kano M, Matsushita K, Rahmutulla B, Yamada S, Shimada H, Kubo S, Hiwasa T, Matsubara H, Nomura F
    • Journal Title

      Gene Ther

      Volume: 23(1) Issue: 1 Pages: 50-56

    • DOI

      10.1038/gt.2015.84

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Elevated levels of autoantibodies against ATP2B4 and BMP-1 in sera of patients with atherosclerosis-related diseases.2015

    • Author(s)
      Hiwasa T, Machida T, Zhang XM, Kimura R, Wang H, Iwase K, Ashino H, Taira A, Arita E, Mine S, Ohno M, Chen PM, Nishi E, Kitamura K, Yamazoe R, Takizawa H, Kashiwado K, Kamitsukasa I, Wada T, Aotsuka A, Kobayashi E, Matsutani T, Iwadate Y, Saeki N, Mori M, Uzawa A, Muto M, Sugimoto K, Kuwabara S, Iwata Y, et al.
    • Journal Title

      Immunome Res

      Volume: 11 Issue: 2 Pages: 097-097

    • DOI

      10.4172/1745-7580.1000097

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Protein kinase Cα-mediated cytotoxic activity of ineupatorolide B from Inula cappa DC. in HeLa cells2015

    • Author(s)
      Dong M, Hiwasa T, Cong B, Shi Q-W, Wang S-M, Kita K, Sugarya S, Suzuki N.
    • Journal Title

      Int J Onco,

      Volume: 47 Issue: 5 Pages: 1839-1844

    • DOI

      10.3892/ijo.2015.3172

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Successful treatment of toxoplasmic encephalitis rapidly diagnosed by a polymerase chain reaction after allogeneic hematopoietic stem cell transplantation: two cases reports and a review of the literature.2015

    • Author(s)
      Miyagi T, Itonaga H, Aosai F, Taguchi J, Norose K, Mochizuki K, Fujii H, Furumoto A, Ohama M, Karimata K , Yamanoha A, Taniguchi H, Sato S , Taira N, Moriuchi Y, Fukushima T, Masuzaki H, Miyazaki Y.
    • Journal Title

      Transplant Infect Dis

      Volume: 印刷中

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] Urinary albumin and transferrin as early diagnostic markers of chronic kidney disease.2015

    • Author(s)
      Maeda H, Sogawa K, Sakaguchi K, Abe S, Sagizaka W, Mochizuki S, Horie W, Watanabe T, Shibata Y, Satoh M, Sanda A, Nomura F, Suzuki J
    • Journal Title

      J Vet Med Sci.

      Volume: 印刷中

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Haploinsufficiency of the c-myc transcriptional repressor FIR, as a dominant negative-alternative splicing model, promoted p53-dependent T-cell acute lymphoblastic leukemia progression by activating Notch12015

    • Author(s)
      Matsushita K, Kitamura K, Rahmutulla B, Tanaka N, Ishige T, Satoh M, Hoshino T, Miyagi S, Mori T, Itoga S, Shimada H, Tomonaga T, Kito M, Nakajima-Takagi Y, Kubo S, Nakaseko C, Hatano M, Miki T, Matsuo M, Fukuyo M, Kaneda A, Iwama A, Nomura F
    • Journal Title

      Oncotarget.

      Volume: 6 Pages: 5102-5117

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Serum cytokine and chemokine profiles in patients with chronic inflammatory demyelinating polyneuropathy.2015

    • Author(s)
      Beppu M, Sawai S, Misawa S, Sogawa K, Mori M, Ishige T, Satoh M, Nomura F, Kuwabara S
    • Journal Title

      Journal of Neuroimmunology

      Volume: 279 Pages: 7-10

    • DOI

      10.1016/j.jneuroim.2014.12.017

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] Increased cell proliferation and differential protein expression induced by low-level Er:YAG laser irradiation in human gingival fibroblasts: proteomic analysis.2015

    • Author(s)
      Ogita M, Tsuchida S, Aoki A, Satoh M, Kado S, Sawabe M, Nanbara H, Kobayashi H, Takeuchi Y, Mizutani K, Sasaki Y, Nomura F, Izumi Y.
    • Journal Title

      Lasers Med Sci.

      Volume: 94 Issue: 7 Pages: 555-61

    • DOI

      10.1007/s10103-014-1691-4

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] Nuclear accumulation of annexin A2 contributes to chromosomal instability by coilin-mediated centromere damage2015

    • Author(s)
      Kazami, T., Nie, H., Satoh, M., Kuga, T., Matsushita, K., Kawasaki, N., Tomonaga, T*., and Nomura, F
    • Journal Title

      Oncogene

      Volume: in press Issue: 32 Pages: 4177-4189

    • DOI

      10.1038/onc.2014.345

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] Congenital toxoplasmosis from a mother with type 2 diabetes mellitus: A case report2014

    • Author(s)
      Sato S, Nishida M, Nasu K, Narahara H, Norose K, Aosai F
    • Journal Title

      J Obstet Gynaecol Res.

      Volume: 40 Issue: 11 Pages: 2158-61

    • DOI

      10.1111/jog.12477

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Human Cystic Echinococcosis in the Nalut District of Western Libya: A Clinico-epidemiological Study2014

    • Author(s)
      Mohamed RM, Abdel-Hafeez EH, Belal US, Norose K, Aosai F
    • Journal Title

      Tropical Medicine and Health

      Volume: 42 Issue: 4 Pages: 177-184

    • DOI

      10.2149/tmh.2014-16

    • NAID

      130004691065

    • ISSN
      1348-8945, 1349-4147
    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Circulating anti-filamin C autoantibody as a potential serum biomarker for low-grade gliomas2014

    • Author(s)
      Adachi-Hayama, M., Adachi, A., Shinozaki, N., Matsutani, T., Hiwasa, T., Takiguchi, M., Saeki, N., Iwadate, Y.
    • Journal Title

      BMC Cancer

      Volume: 14 Issue: 1 Pages: 452-452

    • DOI

      10.1186/1471-2407-14-452

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Inhibition of cell growth by nuclear receptor COUP-TFI: Possible involvement of decorin in growth inhibition2014

    • Author(s)
      Morii, S., Kato, M., Seki, N., Shinmen, N., Iwase, K., Takiguchi, M., Hiwasa, T.
    • Journal Title

      Biochemistry & Physiology

      Volume: S4

    • DOI

      10.4172/2168-9652.s4-001

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] How proteomic ApoE serotyping could impact Alzheimer's disease risk assessment: genetic testing by proteomics.2014

    • Author(s)
      Nishimura M, Satoh M, Matsushita K, Nomura F.
    • Journal Title

      Expert Rev Proteomics.

      Volume: 11 Issue: 4 Pages: 405-7

    • DOI

      10.1586/14789450.2014.936390

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Moesin is a possible target molecule for cytomegalovirus-related Guillain-Barré syndrome.2014

    • Author(s)
      Sawai S, Satoh M, Mori M, Misawa S, Sogawa K, Kazami T, Ishibashi M, Beppu M, Shibuya K, Ishige T, Sekiguchi Y, Noda K, Sato K, Matsushita K, Kodera Y, Nomura F, Kuwabara S
    • Journal Title

      Neurology

      Volume: 83 Issue: 2 Pages: 113-117

    • DOI

      10.1212/wnl.0000000000000566

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Alternative splicing of FBP-interacting repressor coordinates c-Myc, P27Kip1/cyclinE and Ku86/XRCC5 expression as a molecular sensor for bleomycin-induced DNA damage pathway.2014

    • Author(s)
      Rahmutulla B, Matsushita K, Satoh M, Seimiya M, Tsuchida S, Kubo S, Shimada H, Ohtsuka M, Miyazaki M, Nomura F.
    • Journal Title

      Oncotarget

      Volume: 5 Pages: 2404-2417

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Direct application of MALDI-TOF mass spectrometry to cerebrospinal fluid for rapid pathogen identification in a patient with bacterial meningitis.2014

    • Author(s)
      Segawa S, Sawai S, Murata S, Nishimura M, Beppu M, Sogawa K, Watanabe M, Satoh M, Matsutani T, Kobayashi M, Iwadate Y, Kuwabara S, Saeki N, Nomura F
    • Journal Title

      Clinica Chimica Acta

      Volume: 435 Pages: 59-59

    • DOI

      10.1016/j.cca.2014.04.024

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] 眼トキソプラズマ症:マウスモデルにおける前房水中サイトカイン・ケモカイン解析―髄液および血清との比較2017

    • Author(s)
      李 可きん、馮 雪、彦坂健児、野呂瀬一美
    • Organizer
      第86回日本寄生虫学会
    • Place of Presentation
      北海道大学 学術交流会館(北海道 札幌市)
    • Year and Date
      2017-05-28
    • Related Report
      2016 Annual Research Report
  • [Presentation] Utility of the cytochrome c oxidase subunit I gene for the diagnosis of toxoplasmosis using PCR2017

    • Author(s)
      馮 雪、李 可きん、野呂瀬一美、彦坂健児
    • Organizer
      第86回日本寄生虫学会
    • Place of Presentation
      北海道大学 学術交流会館(北海道 札幌市)
    • Year and Date
      2017-05-28
    • Related Report
      2016 Annual Research Report
  • [Presentation] 早期確定診断にnested PCR法が有用であった、HLA半合致同種造血幹細胞移植後に生じたトキソプラズマ脳炎の一例2017

    • Author(s)
      幕内陽介、西本光孝、林良樹、久野雅智、彦坂健児、佐藤哲生、山田康一、中嶋康博、康秀男、中根孝彦、野呂瀬一美、金子幸弘、掛屋弘、日野雅之、中前博久
    • Organizer
      第39回 日本造血細胞移植学会総会
    • Place of Presentation
      くにびきメッセ・島根県民会館(島根県松江市)
    • Year and Date
      2017-03-02
    • Related Report
      2016 Annual Research Report
  • [Presentation] 同種造血幹細胞移植後に神経症状を呈し経過中に増悪した一例~トキソプラズマ症と中枢神経系EBV関連移植後リンパ増殖性疾患~2017

    • Author(s)
      眞弓あずさ、池亀和博、山下鷹也、藤野聡仁、寺本昌弘、丸山聡、井上貴之、海田勝仁、玉置広哉、相馬俊裕、野呂瀬一美、加藤康幸、小川啓恭
    • Organizer
      第39回 日本造血細胞移植学会総会
    • Place of Presentation
      くにびきメッセ・島根県民会館(島根県松江市)
    • Year and Date
      2017-03-02
    • Related Report
      2016 Annual Research Report
  • [Presentation] 法医解剖前CTにおいて小腸内に条虫の存在が示唆された無鉤条虫症の1例2017

    • Author(s)
      星岡佑美、吉田真衣子、槇野陽介、彦坂健児、野呂瀬一美、岩瀬博太郎
    • Organizer
      第28回日本臨床寄生虫学会大会
    • Place of Presentation
      国立国際医療研究センター(東京都)
    • Related Report
      2016 Annual Research Report
  • [Presentation] 全身性エリテマトーデス(SLE)再燃時に播種性トキソプラズマ症の診断に至った一例2017

    • Author(s)
      古矢裕樹、鈴木一正、彦坂健児、古田俊介、池田啓、中島裕史、野呂瀬一美。
    • Organizer
      第28回日本臨床寄生虫学会大会
    • Place of Presentation
      国立国際医療研究センター(東京都)
    • Related Report
      2016 Annual Research Report
  • [Presentation] 動脈硬化症の患者血清において上昇する抗体マーカーATP2B42016

    • Author(s)
      日和佐隆樹、張暁萌、木村理沙、工藤孝、土居洋文、中村利華、冨吉郷、新免奈津子、黒田英行
    • Organizer
      第39回日本分子生物学会
    • Place of Presentation
      パシフィコ横浜 (神奈川県 横浜市)
    • Year and Date
      2016-11-30
    • Related Report
      2016 Annual Research Report
  • [Presentation] 急性冠症候群におけるナルディライシンNardilycinの診断バイオマーカーとしての有用性の検討2016

    • Author(s)
      大野美紀子, 陳博敏, 日和佐隆樹, 西清人, 西城さやか, 森田雄介, 松田真太郎, 桑原康秀, 尾野亘, 今井逸雄, 井上勝美, 村井達哉, 北徹, 木村剛, 西英一郎
    • Organizer
      第39回日本分子生物学会
    • Place of Presentation
      パシフィコ横浜 (神奈川県 横浜市)
    • Year and Date
      2016-11-30
    • Related Report
      2016 Annual Research Report
  • [Presentation] 脳原発悪性リンパ腫を合併したトキソプラズマ脳炎の再発例2016

    • Author(s)
      鷲野 巧弥, 矢嶋 敬史郎, 福島 一彰, 佐々木 秀悟, 関谷 綾子
    • Organizer
      第30回日本エイズ学会学術集会
    • Place of Presentation
      かごしま県民交流センター(鹿児島県鹿児島市)
    • Year and Date
      2016-11-24
    • Related Report
      2016 Annual Research Report
  • [Presentation] The role of mass spectrometry in clinical laboratory: focusing on vitamin D testing.2016

    • Author(s)
      Mamoru Sato
    • Organizer
      The 32nd World Congress of Biomedical Laboratory Science - IFBLS 2016
    • Place of Presentation
      神戸国際会議場(兵庫県 神戸市)
    • Year and Date
      2016-08-31
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 動脈硬化関連疾患の患者血清におけるBMP-1抗体レベルの上昇2016

    • Author(s)
      日和佐隆樹、張暁萌、木村理沙、中村利華、冨吉郷、新免奈津子、黒田英行
    • Organizer
      第21回日本病態プロテアーゼ学会学術集会
    • Place of Presentation
      千里ライフサイエンスセンター(大阪府豊中市)
    • Year and Date
      2016-08-05
    • Related Report
      2016 Annual Research Report
  • [Presentation] Development and validation of simultaneous measurement of four vitamin D metabolites in serum by LC-MS/MS for clinical laboratory.2016

    • Author(s)
      Satoh M, Ishige T, Ogawa S, Nishimura M, Matsushita K, Higashi T, Nomura F
    • Organizer
      The Official 68th AACC Annual Scientific Meeting & Clinical Lab Expo
    • Place of Presentation
      Pennsylvania Convention Center (USA, Philadelphia)
    • Year and Date
      2016-07-31
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] ブドウ膜炎を合併した皮膚Rosai Dorfman病の自験1例と同様既報告の比較検討2016

    • Author(s)
      福本 毅、三木 康子、坂口 正展、正木 太朗、福永 淳、岡 昌宏、皿山 泰子、野呂瀬一美、伊藤 智雄、錦織千佳子
    • Organizer
      第115回 日本皮膚科学会総会
    • Place of Presentation
      国立京都国際会館 (京都府京都市)
    • Year and Date
      2016-06-03
    • Related Report
      2016 Annual Research Report
  • [Presentation] Establishment of a murine model of malarial retinopathy2016

    • Author(s)
      Feng Xue, Kenji Hikosaka, Li Kexin, Tetsuo Sato, Hiroyuki Matsuoka, Kazumi Norose.
    • Organizer
      第85回日本寄生虫学会総会
    • Place of Presentation
      宮崎市民プラザ(宮崎県宮崎市)
    • Year and Date
      2016-03-19
    • Related Report
      2015 Research-status Report
  • [Presentation] マラリア原虫の遺伝子点変異によるアトバコン耐性獲得様式の解明2016

    • Author(s)
      彦坂 健児、本間 一、松崎 素道、野呂瀬 一美、北 潔
    • Organizer
      第85回日本寄生虫学会総会
    • Place of Presentation
      宮崎市民プラザ(宮崎県宮崎市)
    • Year and Date
      2016-03-19
    • Related Report
      2015 Research-status Report
  • [Presentation] 造血幹細胞移植後トキソプラズマ肺炎・播種型トキソプラズマ症の臨床的特徴の検討2016

    • Author(s)
      住 昌彦、倉石 博、渡辺 正秀、野呂瀬一美、彦坂 健児、貝梅 紘子、武田 航、桐原 健彦、栗原 太郎、佐藤慶二郎、植木 俊充、廣島 由紀、小林 光
    • Organizer
      第38回日本造血細胞移植学会総会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2016-03-04
    • Related Report
      2015 Research-status Report
  • [Presentation] 早期診断・早期治療を行い救命し得た、臍帯血移植後の播種性トキソプラズマ症2016

    • Author(s)
      那須野 将、栗原 太郎、貝梅 紘子、武田 航、桐原 健彦、佐藤慶二郎、植木 俊充、廣島 由紀、住 昌彦、上野真由美、市川 直明、彦坂 健児、野呂瀬一美、小林 光
    • Organizer
      第38回日本造血細胞移植学会総会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2016-03-04
    • Related Report
      2015 Research-status Report
  • [Presentation] 妊娠中の母体トキソプラズマIgG Avidityが高値であったにも関わらず先天性トキソプラズマ症の診断に至った2例2016

    • Author(s)
      新谷光央、唐木田智子、丸山慎介、市之宮健二、彦坂健児、佐藤哲生、野呂瀬一美
    • Organizer
      第27回日本臨床寄生虫学会総会
    • Place of Presentation
      しいのき迎賓館(石川県金沢市)
    • Related Report
      2016 Annual Research Report
  • [Presentation] 動脈硬化関連疾患に対応する血清抗体マーカーの同定.2015

    • Author(s)
      日和佐隆樹
    • Organizer
      第38回日本分子生物学会・第88回日本生化学会 合同大会
    • Place of Presentation
      神戸ポートアイランド(兵庫県神戸市)
    • Year and Date
      2015-12-01
    • Related Report
      2015 Research-status Report
  • [Presentation] Early diagnosis of toxoplasmosis after CBT by PCR analysis of peripheral blood2015

    • Author(s)
      岡田隆宏、高橋 勉、伊藤 俊輔、岡田 祐介、高橋 史匡、高見 咲、熊野御堂 慧、足立 康二、池尻 文良、城 有美、大西 千恵、川上 耕史、井上政弥、三宅 隆明、鈴木 律朗、鈴宮 淳司、野呂瀬一美
    • Organizer
      第77回日本血液学会学術集会
    • Place of Presentation
      石川県立音楽堂(石川県金沢市)
    • Year and Date
      2015-10-16 – 2015-10-18
    • Related Report
      2014 Research-status Report
  • [Presentation] マラリア原虫の遺伝子点変異による薬剤耐性獲得様式の解明2015

    • Author(s)
      彦坂 健児、本間 一、松崎 素道、野呂瀬 一美、北 潔
    • Organizer
      第23回分子寄生虫学ワークショップ/第13回分子寄生虫・マラリア研究フォーラム合同大会
    • Place of Presentation
      帯広畜産大学原虫病研究センターPKホール(北海道帯広市)
    • Year and Date
      2015-08-30
    • Related Report
      2015 Research-status Report
  • [Presentation] ペプチドアレイを用いた動脈硬化マーカーの選別.2015

    • Author(s)
      日和佐隆樹、國松己歳、張暁萌、木村理沙、中村利華、冨吉郷、新免奈津子、黒田英行
    • Organizer
      第20回日本病態プロテアーゼ学会
    • Place of Presentation
      ANAクラウンプラザホテルグランコート名古屋(愛知県名古屋市)
    • Year and Date
      2015-08-21
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] 大腸癌血清抗体マーカーの探索.2015

    • Author(s)
      石井清香、日和佐隆樹、宮内秀聡、松原久裕
    • Organizer
      第70回日本消化器外科学会総会
    • Place of Presentation
      アクトシティ浜松、オークラアクトシティホテル浜松、ホテルクラウンパレス浜松(静岡県浜松市)
    • Year and Date
      2015-07-15
    • Related Report
      2015 Research-status Report
  • [Presentation] メトトレキセート内服中にトキソプラズマ脳症の発症が疑われた1例2015

    • Author(s)
      松浦潤 藤並潤 石井亮太郎 藤井明弘 野呂瀬一美 水野敏樹
    • Organizer
      第102回日本神経学会近畿地方会
    • Place of Presentation
      大阪国際会議場(大阪府大阪市)
    • Year and Date
      2015-07-04
    • Related Report
      2014 Research-status Report
  • [Presentation] 法医解剖において発見された日本住血吸虫卵の法医学的考察2015

    • Author(s)
      本村あゆみ、野呂瀬一美、太田伸生、岩瀬博太郎
    • Organizer
      第85回日本臨床寄生虫学会
    • Place of Presentation
      栃木県総合文化センター(栃木県宇都宮市)
    • Year and Date
      2015-06-20
    • Related Report
      2015 Research-status Report
  • [Presentation] 一過性脳虚血発作に対応する血清抗体マーカーの同定2015

    • Author(s)
      日和佐隆樹、峯清一郎、木村理沙、張暁萌、瀧口正樹、小林英一、佐伯直勝、町田利生、中村利華、冨吉郷、新免奈津子、黒田英行
    • Organizer
      第11回日本臨床プロテオーム研究会
    • Place of Presentation
      国際研究交流会館(東京都中央区)
    • Year and Date
      2015-05-23
    • Related Report
      2015 Research-status Report
  • [Presentation] Early diagnosis of toxoplasmosis after CBT by PCR analysis of peripheral blood2015

    • Author(s)
      岡田隆宏、高橋 勉、伊藤 俊輔、岡田 祐介、高橋 史匡、高見 咲、熊野御堂 慧、足立 康二、池尻 文良、城 有美、大西 千恵、川上 耕史、井上政弥、三宅 隆明、鈴木 律朗、鈴宮 淳司、野呂瀬一美
    • Organizer
      第21回中国・四国造血幹細胞移植研究会
    • Place of Presentation
      広島国際会議場(広島県広島市)
    • Year and Date
      2015-05-09
    • Related Report
      2014 Research-status Report
  • [Presentation] Peyer's patches are the primary invasion sites of Toxoplasma gondii regardless of the host immune status.2015

    • Author(s)
      Tetsuya Mitsunaga, Kexin Li, Xue Feng, Fumie Aosai, Kazumi Norose
    • Organizer
      第84回日本寄生虫学会大会
    • Place of Presentation
      杏林大学三鷹キャンパス(東京都三鷹市)
    • Year and Date
      2015-03-21 – 2015-03-22
    • Related Report
      2014 Research-status Report
  • [Presentation] 質量分析の基礎知識2015

    • Author(s)
      佐藤守
    • Organizer
      平成26年度高度先端的医学セミナー 質量分析に関する研修会
    • Place of Presentation
      日本臨床検査技師会館(東京都大田区)
    • Year and Date
      2015-03-14 – 2015-03-15
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] 動脈硬化症に対応する血清抗体マーカーの同定2014

    • Author(s)
      日和佐隆樹
    • Organizer
      第37 回日本分子生物学会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2014-11-25 – 2014-11-27
    • Related Report
      2014 Research-status Report
  • [Presentation] DAPTAD誘導体化を用いたLC-MS/MSによる血清ビタミンD台車物の4項目同時定量2014

    • Author(s)
      佐藤守、石毛崇之、小川祥二郎、西村基、松下一之、東達也、野村文夫
    • Organizer
      第39回 日本医用マススペクトル学会年会
    • Place of Presentation
      三井ガーデンホテル千葉(千葉県千葉市)
    • Year and Date
      2014-10-16 – 2014-10-17
    • Related Report
      2014 Research-status Report
  • [Presentation] イムノアフィニティー抽出DAPTAD誘導体化LC-MS/MSによる血清25OH-ビタミンD及び1,25(OH)2-ビタミンDの同時定量2014

    • Author(s)
      石毛崇之、佐藤守、小川祥二郎、西村基、土田祥央、澤井摂、松下一之、東達也、野村文夫
    • Organizer
      第39回 日本医用マススペクトル学会年会
    • Place of Presentation
      三井ガーデンホテル千葉 (千葉県千葉市)
    • Year and Date
      2014-10-16 – 2014-10-17
    • Related Report
      2014 Research-status Report
  • [Presentation] ネコ慢性腎不全における尿を用いた早期診断マーカーの探索2014

    • Author(s)
      前田浩人、前川武大、柴田悠衣、阿部沙織、堀江和香、望月俊輔、渡辺俊文、佐藤守、三田明弘、野村文夫、曽川和幸
    • Organizer
      第39回 日本医用マススペクトル学会年会
    • Place of Presentation
      三井ガーデンホテル千葉 (千葉県千葉市)
    • Year and Date
      2014-10-16 – 2014-10-17
    • Related Report
      2014 Research-status Report
  • [Presentation] キウイフルーツアレルギーにおけるアレルゲン蛋白質の解析2014

    • Author(s)
      河原彩花、曽川一幸、佐藤守、三田明弘、下條直樹、野村文夫
    • Organizer
      第39回 日本医用マススペクトル学会年会
    • Place of Presentation
      三井ガーデンホテル千葉 (千葉県千葉市)
    • Year and Date
      2014-10-16 – 2014-10-17
    • Related Report
      2014 Research-status Report
  • [Presentation] ナッツアレルギーにおけるアレルゲン蛋白質の解析2014

    • Author(s)
      安東圭奈美、曽川一幸、佐藤守、三田明弘、下條直樹、野村文夫
    • Organizer
      第39回 日本医用マススペクトル学会年会
    • Place of Presentation
      三井ガーデンホテル千葉 (千葉県千葉市)
    • Year and Date
      2014-10-16 – 2014-10-17
    • Related Report
      2014 Research-status Report
  • [Presentation] プロテオーム解析を用いた歯周病疾患マーカー探索2014

    • Author(s)
      土田祥央、佐藤守、曽川一幸、川島祐介、石毛崇之、別府美奈子、澤井摂、西村基、小寺義男、松下一之、野村文夫
    • Organizer
      第39回 日本医用マススペクトル学会年会
    • Place of Presentation
      三井ガーデンホテル千葉 (千葉県千葉市)
    • Year and Date
      2014-10-16 – 2014-10-17
    • Related Report
      2014 Research-status Report
  • [Presentation] 質量分析計を活用したがん培養細胞の分泌物解析とサイトケラチン断片の探索2014

    • Author(s)
      陳健嘉、西村基、西村里美、石毛崇之、佐藤守、松下一之、野村文夫
    • Organizer
      第39回 日本医用マススペクトル学会年会
    • Place of Presentation
      三井ガーデンホテル千葉 (千葉県千葉市)
    • Year and Date
      2014-10-16 – 2014-10-17
    • Related Report
      2014 Research-status Report
  • [Presentation] MALDI-TOF MSを用いた細菌性髄膜炎の起炎菌迅速同定2014

    • Author(s)
      別府美奈子、澤井摂、瀬川俊介、村田正太、曽川一幸、渡邊正治、西村基、佐藤守、松下一之、野村文夫
    • Organizer
      第39回 日本医用マススペクトル学会年会
    • Place of Presentation
      三井ガーデンホテル千葉 (千葉県千葉市)
    • Year and Date
      2014-10-16 – 2014-10-17
    • Related Report
      2014 Research-status Report
  • [Presentation] 動脈硬化性脳梗塞に対応する血清抗体マーカーの同定2014

    • Author(s)
      日和佐隆樹、峯清一郎、木村理沙、佐藤万里子、張暁萌、瀧口正樹、小林英一、岩立康男、佐伯直勝、後藤憲一郎、松村竜太郎、杉山隆夫、町田利生、工藤孝、土居洋文、中村利華、冨吉郷、新免奈津子、黒田英行
    • Organizer
      第87回日本生化学会
    • Place of Presentation
      国立京都国際会館・グランドプリンスホテル京都(京都府京都市)
    • Year and Date
      2014-10-15 – 2014-10-18
    • Related Report
      2014 Research-status Report
  • [Presentation] 動脈硬化関連疾患の血清抗体マーカーの開発2014

    • Author(s)
      日和佐隆樹
    • Organizer
      第87回日本生化学会
    • Place of Presentation
      国立京都国際会館・グランドプリンスホテル京都(京都府京都市)
    • Year and Date
      2014-10-15 – 2014-10-18
    • Related Report
      2014 Research-status Report
  • [Presentation] 消化管癌患者におけるRalA抗原に対する免疫反応.2014

    • Author(s)
      島田英昭、谷島聡、小池淳一、松下一之、野村文夫、日和佐隆樹、田川雅俊
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2014-09-25 – 2014-09-27
    • Related Report
      2014 Research-status Report
  • [Presentation] 脳梗塞および糖尿病の診断に有用な血清BMP-1抗体マーカー2014

    • Author(s)
      日和佐隆樹、佐藤万里子、木村理沙、瀧口正樹、峯清一郎、竹本稔、小林一貴、河村治清、石橋亮一、横手幸太郎、中村利華、冨吉郷、新免奈津子、黒田英行
    • Organizer
      第19回日本病態プロテアーゼ学会
    • Place of Presentation
      千里ライフサイエンスセンター(大阪府豊中市)
    • Year and Date
      2014-08-08 – 2014-08-09
    • Related Report
      2014 Research-status Report
  • [Presentation] Interactions between SF3b1(SAP155) and FUSE-binding protein-interacting repressor (FIR) links c-Myc and P27Kip1 expression through GeLC-MS analysis2014

    • Author(s)
      松下一之、佐藤守、朝長毅、野村文夫
    • Organizer
      日本プロテオーム学会2014年会
    • Place of Presentation
      つくば国際会議場(茨木県つくば市)
    • Year and Date
      2014-07-17 – 2014-07-18
    • Related Report
      2014 Research-status Report
  • [Presentation] 全身性エリテマトーデス患者の自己抗体から選別された脳梗塞血清抗体マーカー2014

    • Author(s)
      日和佐隆樹、後藤憲一郎、松村竜太郎、杉山隆夫、瀧口正樹
    • Organizer
      第10回日本臨床プロテオーム研究会
    • Place of Presentation
      京王プラザホテル(東京都新宿区)
    • Year and Date
      2014-05-10
    • Related Report
      2014 Research-status Report
  • [Book] 今日の治療指針 私はこう治療している2016

    • Author(s)
      野呂瀬 一美
    • Total Pages
      2096
    • Publisher
      医学書院
    • Related Report
      2015 Research-status Report
  • [Book] 今日の治療指針 2016年度版 私はこう治療している トキソプラズマ2016

    • Author(s)
      野呂瀬一美
    • Publisher
      医学書院
    • Related Report
      2014 Research-status Report
  • [Remarks] 千葉大学大学院医学研究院中核研究部門 生命機能治療額研究講座 感染生体防御学

    • URL

      http://www.m.chiba-u.ac.jp/class/infection-hostdefense/

    • Related Report
      2015 Research-status Report
  • [Remarks] 千葉大学大学院医学研究院感染生体防御学ホームページ

    • URL

      http://www.m.chiba-u.ac.jp/class/infection-hostdefense/

    • Related Report
      2014 Research-status Report
  • [Patent(Industrial Property Rights)] 動脈硬化の検出方法2016

    • Inventor(s)
      黒田英行、中村利華、冨吉郷、日和佐隆樹
    • Industrial Property Rights Holder
      黒田英行、中村利華、冨吉郷、日和佐隆樹
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2016-222657
    • Filing Date
      2016-11-15
    • Related Report
      2016 Annual Research Report
  • [Patent(Industrial Property Rights)] デオキシハイプシン・シンターゼ遺伝子を指標として用いる動脈硬化の検出方法2014

    • Inventor(s)
      中村利華、黒田英行、冨吉郷、日和佐隆樹、瀧口正樹、佐伯直勝
    • Industrial Property Rights Holder
      千葉大学及び藤倉化成株式会社
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2014-226847
    • Filing Date
      2014-11-07
    • Related Report
      2014 Research-status Report

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Published: 2014-04-04   Modified: 2018-03-22  

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