Project/Area Number |
26460777
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Epidemiology and preventive medicine
|
Research Institution | Tohoku Medical and Pharmaceutical University |
Principal Investigator |
SATO Kenichi 東北医科薬科大学, 薬学部, 教授 (30158935)
|
Co-Investigator(Kenkyū-buntansha) |
川上 準子 東北医科薬科大学, 薬学部, 講師 (40438560)
星 憲司 東北医科薬科大学, 薬学部, 講師 (20405913)
青木 空眞 東北医科薬科大学, 薬学部, 助教 (40584462)
|
Research Collaborator |
YOSHIDA Katsumi 東北公済病院, 医学管理センター, 医師
MORI Kouki JR仙台病院, 健康管理センター長
NAKAGAWA Yoshinori 仙台甲状腺クリニック, 院長
YAMAGISHI Toshio 東北公済病院, 内科部長
|
Project Period (FY) |
2014-04-01 – 2017-03-31
|
Project Status |
Completed (Fiscal Year 2016)
|
Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2016: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
|
Keywords | 甲状腺機能異常 / 基本的検査 / スクリーニング / 時系列データ / パターン認識手法 / 人工知能 / 健診・外来 / インフォマティクス / 診断支援 |
Outline of Final Research Achievements |
We developed a new simple, low-cost method for detecting patients with overt thyroid dysfunction (PTD) using the combination of six routine tests already measured without measuring thyroid hormone. The existing procedure comprised 6 routine tests (alkaline phosphatase (ALP), serum creatinine (S-Cr), total cholesterol (TC), heart rate (HR), lactate dehydrogenase (LDH) and red blood cell (RBC)). We performed this screening for many participants more than 20000 attending health-checkup at Ningen Docks in JR Sendai Hospital and Tohoku Kousai Hospital, and found more than 40 PTDs, most of them was suspected of thyroid dysfunction by a medical examination. Furthermore, it was found that a very highly-detailed prediction not to be affected by the individual difference was possible when there was the value last time.
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