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Development of novel non-drug heart failure therapy for patients with cardiac rehabilitation difficulties

Research Project

Project/Area Number 26461054
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Cardiovascular medicine
Research InstitutionAkita University

Principal Investigator

Iino Kenji  秋田大学, 医学部, 講師 (30400485)

Co-Investigator(Kenkyū-buntansha) 伊藤 宏  秋田大学, その他部局等, 特任教授 (10232464)
渡邊 博之  秋田大学, 医学(系)研究科(研究院), 教授 (80323145)
Project Period (FY) 2014-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Keywords心臓リハビリテーション / リハビリ困難 / 遠隔虚血プレコンディショニングRIPC / 吸気筋トレーニングIMT / 遠隔虚血プレコンディショニング / 吸気筋トレーニング / 慢性心不全
Outline of Final Research Achievements

Efficacy of cardiac rehabilitation is reported for the patient with chronic heart failure. However, there are a lot of patients with exercise cardiac rehabilitation difficulties. Therefore, this study examined that the new rehabilitation for exercise impossible patients. (a) Remote ischemic preconditioning (RIPC) prevent the progression of the renal failure and decrease the oxidative stress. (b) Inspiratory muscle training (IMT) improve the symptoms in early phase, and decrease the level of BNP later. Conclusion: RIPC and IMT may have a possibility of the one of the New rehabilitation in patients with difficult for exercise rehabilitation.

Report

(5 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • 2014 Research-status Report
  • Research Products

    (5 results)

All 2017 2016 2015 2014

All Presentation (5 results)

  • [Presentation] 運動リハビリ困難患者に対する呼気筋トレーニングの有用性2017

    • Author(s)
      飯野健二、渡邊博之、相原健志、高橋裕介、阿部起実、木村俊介、新保麻衣、飯野貴子、小坂俊光、伊藤宏
    • Organizer
      23回日本心臓リハビリテーション学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 運動リハビリ困難患者に対する吸気筋トレーニングの有用性2017

    • Author(s)
      飯野健二
    • Organizer
      日本心臓リハビリテーション学会学術集会
    • Place of Presentation
      岐阜
    • Related Report
      2016 Research-status Report
  • [Presentation] Clinical applications of Remote Ischemic Preconditioning - How can we provide the benefit of RIPC ? -2016

    • Author(s)
      飯野健二
    • Organizer
      第80回日本循環器学会総会
    • Place of Presentation
      仙台
    • Year and Date
      2016-03-18
    • Related Report
      2015 Research-status Report
  • [Presentation] Renoprotective Action of Remote Ischemic Preconditioning Promises a Favorable Renal Prognosis in Patients Undergoing Coronary Angiography2015

    • Author(s)
      飯野健二
    • Organizer
      第79回日本循環器学会総会
    • Place of Presentation
      大阪
    • Year and Date
      2015-04-26
    • Related Report
      2015 Research-status Report
  • [Presentation] Remote Ischemic Preconditioning (RIPC)の臓器保護作用2014

    • Author(s)
      飯野健二
    • Organizer
      第62回心臓病学会
    • Place of Presentation
      仙台
    • Year and Date
      2014-09-26 – 2014-09-28
    • Related Report
      2014 Research-status Report

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Published: 2014-04-04   Modified: 2019-03-29  

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