| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Outline of Final Research Achievements |
We evaluated the effect of one-time umbilical cord milking on 3-year neurodevelopment outcome in premature infants born less than 28 weeks of gestation compared with early umbilical cord clamping by using randomized controlled trial. At 3-year, we could follow the 112 infants (57 in the umbilical cord milking group, 55 in the early cord clamping group). The incidence of cerebral palsy and Gross Motor Function Classification score ≧ 1 were significantly lower in the umbilical cord milking group compared with in the early cord clamping group. Mean values of the developmental quotient (DQ) by using New Kyoto Scale of Psychological Development were simillar between the two groups, but The incidence of DQ <70 in the milking group was lower compared with the early cord clamping group.
One-time umbilical cord milking might be useful for prevention of neurodevelopment disputers in premature infants without both interrupting resuscitation and additional cost.
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