| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Outline of Final Research Achievements |
The objective of this study was to develop the bone graft materials by combining scaffold-free cell construct fabrication system and freeze dry technique. With the usage of appropriate pretreatments, bone-like constructs, fabricated through osteoinduction of aggregate of bone marrow stromal cells, were able to maintain extracellular matrix and mineralized matrices even after being freeze-dried. The freeze-dried bone like constructs achieved in this study are expected to be used as a useful biomaterial for bone regenerative medicine.
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