| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2015: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Outline of Final Research Achievements |
It is thought that the glycogen is one of key sources in supplying energy, nucleic acid, and lipid necessary for cancer cell proliferation in oral squamous cell carcinoma. The purpose of this study is to analyze metabolism of glycogen and to elucidate metabolism abnormality in oral squamous cell carcinoma. The results of this study suggested that oral squamous cell carcinoma cell got energy not simply in the glycolytic pathway, a simple course called the glycogen → glucose → glycolytic pathway, and they also suggested the possibility that oral squamous cell carcinoma might get energy by amino acid metabolism. It will be necessary to examine the metabolism of amino acid, glucuronic acid, and nucleic acids etc., and to analyze the specificity in the metabolism of oral squamous cell carcinoma.
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