Study on the restoration factor of the self-conclusion type organization reproduction material by proteomic analysis
Project/Area Number |
26463065
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Surgical dentistry
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Research Institution | Shimane University |
Principal Investigator |
Sekine Joji 島根大学, 医学部, 教授 (20236095)
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Co-Investigator(Kenkyū-buntansha) |
秀島 克巳 島根大学, 医学部, 助教 (80593673)
|
Project Period (FY) |
2014-04-01 – 2018-03-31
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Project Status |
Completed (Fiscal Year 2017)
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Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2016: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
|
Keywords | 頬脂肪体 / プロテオーム解析 / マイクロアレイ / 組織学的評価 |
Outline of Final Research Achievements |
Pedicled buccal fat pad (BFP) fills an anatomical gap consisted of the buccinator muscle, the masseter muscle, and the ramus of the mandible. This study sought to evaluate the applicability of pedicled BFP grafting with a higher number of cases than our previous report in 2015.We evaluated them based on the following criteria: the epithelialisation, the graft infection, the fistula recurrence, the facial contour deficiency, the limitation of the mouth opening, and the facial nerve palsy. Besides, by means of gene expression microarray analysis, we have investigated genes which are potential targets for epithelialisation of BFP.Complete epithelialisation of the BFP occurred within 4 weeks in most of the grafting's. Four weeks postsurgery, no complications occurred in most of the grafting's. BFP grafting appears to be feasible for the reconstruction of surgical defects in the oral region.
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Report
(5 results)
Research Products
(14 results)
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[Journal Article] Applicability of buccal fat pad grafting for oral reconstruction2016
Author(s)
Aya Yoshino, Yoshiki Nariai, Masaaki Karino, Hiroto Tatsumi, Koji Tsunematsu, Yutaro Takamura, Takahiro Kanno, Chie Yanai, Seiji Kondo, Joji Sekine
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Journal Title
40th World Congress of the International College of Surgeons, 62nd Annual Congress of the International College of Surgeons Japan Section, Proceedings
Volume: -
Pages: 354
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[Presentation] Applicability of buccal fat pad grafting for oral reconstruction2016
Author(s)
Aya Yoshino, Yoshiki Nariai, Masaaki Karino, Hiroto Tatsumi, Koji Tsunematsu, Yutaro Takamura, Takahiro Kanno, Chie Yanai, Seiji Kondo, Joji Sekine
Organizer
40th World Congress of the International College of Surgeons, 62nd Annual Congress of the International College of Surgeons Japan Section
Place of Presentation
Kyoto International Conference Center
Year and Date
2016-10-25 – 2016-10-25
Related Report
Int'l Joint Research
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[Presentation] Applicability of buccal fat pad grafting for oral reconstruction2015
Author(s)
Aya Yoshino, Yoshiki Nariai, Masaaki Karino, Hiroto Tatsumi, Koji Tsunematsu, Yuta Yoshiki Nariai, Masaaki Karino, Hiroto Tatsumi, Koji Tsunematsu, Yutaro Takamura, Takahiro Kanno, Chie Yanai, Seiji Kondo, Joji Sekine
Organizer
第39回日本頭頸部癌学会・第4回アジア頭頸部癌学会
Place of Presentation
神戸国際会議場
Year and Date
2015-06-04
Related Report
Int'l Joint Research
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[Presentation] Applicability of buccal fat pad grafting for oral reconstruction2014
Author(s)
Aya Yoshino, Yoshiki Nariai, Masaaki Karino, Hiroto Tatsumi, Koji Tsunematsu, Yutaro Takamura Takahiro Kanno, Chie Yanai, Seiji Kondo, Joji Sekine
Organizer
The 39th Bienial World Congress of the International College of Surgeons
Place of Presentation
Bali International Convention Centre, The Westin Hotel, Nusa Dua, Bari, Indonesia
Year and Date
2014-10-22 – 2014-10-22
Related Report
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[Presentation] Applicability of buccal fat pad grafting for oral reconstruction2014
Author(s)
Aya Yoshino, Yoshiki Nariai, Masaaki Karino, Yoko Toshihiro, Hiroto Tatsumi, Kohji Tsunematsu, Yutaro Takamura, Takahiro Kanno, Chie Yanai, Seiji Kondo, Joji Sekine
Organizer
The International College of Surgeon The 60th Annual Congress of the Japan Section
Place of Presentation
ホテルメトロポリタン高崎
Year and Date
2014-06-14 – 2014-06-14
Related Report