| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
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| Outline of Final Research Achievements |
Gene expression is a stochastic process. Due to this, gene expression levels in single cells are inherently heterogeneous even among a genetically identical cell population. In this work, we challenged to develop a method to visualize single-molecule mRNA and protein productions in single eukaryotic cells. The results suggest that the protein translation process is a major source to regulate gene expression noise.
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