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Embryological basis of diversification of avian morphology: developmental mechanism that enables the penguin to fly in the water

Research Project

Project/Area Number 26650073
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Developmental biology
Research InstitutionTohoku University

Principal Investigator

TAMURA Koji  東北大学, 生命科学研究科, 教授 (70261550)

Project Period (FY) 2014-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords多様性進化 / 鳥類 / ペンギン / 前肢 / 共有派生形質 / 形態形成
Outline of Final Research Achievements

We established experimental basis of penguin embryology. The basis enabled us to transfer penguin eggs from an aquarium in Tokyo to our laboratory in Sendai, incubate eggs, and manipulate penguin embryos. We found that developmental defects of the first digit in the penguin forelimb (wing) start at stage 27 and that decrease of cell proliferation and ectopic expression of bmp4 can be seen during the process. We also described developmental process of flight feather formation in the chick and penguin embryos. We are now preparing some manuscripts for publishing the data on penguin wing development. Thanks to this project, a model system of penguin embryology was successfully established for the first time in the world.

Report

(3 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • Research Products

    (10 results)

All 2016 2015 2014

All Journal Article (5 results) (of which Peer Reviewed: 5 results,  Acknowledgement Compliant: 4 results,  Open Access: 3 results) Presentation (5 results) (of which Int'l Joint Research: 2 results,  Invited: 3 results)

  • [Journal Article] AP-2β is a transcriptional regulator for determination of digit length in tetrapods.2015

    • Author(s)
      Seki R, Kitajima K, Matsubara H, Suzuki T, Saito D, Yokoyama H, Tamura K.
    • Journal Title

      Dev Biol.

      Volume: 407 Issue: 1 Pages: 75-89

    • DOI

      10.1016/j.ydbio.2015.08.006

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Evidence for an amphibian sixth digit.2015

    • Author(s)
      Hayashi S., Kobayashi T., Yano T., Kamiyama N., Egawa S., Seki R., Takizawa K., Okabe M., Yokoyama H. and Tamura K.
    • Journal Title

      Zoological Letters.

      Volume: 1 Issue: 1 Pages: 17-17

    • DOI

      10.1186/s40851-015-0019-y

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Roles of Hippo signaling pathway in size control of organ regeneration2015

    • Author(s)
      Hayashi, S., Yokoyama, H. and Tamura, K.
    • Journal Title

      Development Growth and Differentiation

      Volume: 未定 Issue: 4 Pages: 341-351

    • DOI

      10.1111/dgd.12212

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Growth and differentiation of a long bone in limb development, repair and regeneration2014

    • Author(s)
      S. Egawa, S. Miura, H. Yokoyama, T. Endo and K. Tamura
    • Journal Title

      Dev Growth Differ

      Volume: 56 Issue: 5 Pages: 410-24

    • DOI

      10.1111/dgd.12136

    • NAID

      40020109556

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Transcriptional regulators in the Hippo signaling pathway control organ growth in Xenopus tadpole tail regeneration2014

    • Author(s)
      S. Hayashi, H. Ochi, H. Ogino, A. Kawasumi, Y. Kamei, K. Tamura and H. Yokoyama
    • Journal Title

      Dev Biol

      Volume: 396 Issue: 1 Pages: 31-41

    • DOI

      10.1016/j.ydbio.2014.09.018

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Presentation] Developmental and genomic aspects of macroevolution in vertebrates.2016

    • Author(s)
      田村宏治
    • Organizer
      Avian Model Systems 9: A New Integrative Platform
    • Place of Presentation
      Taipei (Taiwan)
    • Year and Date
      2016-03-29
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Anuran limb regeneration: an intermediary model between amphibians and mammals.2015

    • Author(s)
      田村宏治
    • Organizer
      10th Annual Wisconsin Stem Cell Symposium
    • Place of Presentation
      Madison (USA)
    • Year and Date
      2015-04-22
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Anuran limb regeneration: an intermediary model between amphibians and mammals.2015

    • Author(s)
      田村宏治
    • Organizer
      Wisconsin Stem Cell Symposium
    • Place of Presentation
      BioPharmaceutical Technology Center (Madison, USA)
    • Year and Date
      2015-04-22
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] 鳥類を特徴づける形態と発生機構とゲノム配列2014

    • Author(s)
      田村宏治
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜 (横浜)
    • Year and Date
      2014-11-26
    • Related Report
      2014 Research-status Report
  • [Presentation] 鳥は本当に恐竜なのか!?-動物学の威力と魅力-2014

    • Author(s)
      田村宏治
    • Organizer
      日本動物学会第85回仙台大会2014
    • Place of Presentation
      東北大学川内北キャンパス (仙台)
    • Year and Date
      2014-09-13
    • Related Report
      2014 Research-status Report

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Published: 2014-04-04   Modified: 2017-05-10  

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