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Intravital imaging of auditory function and pathology

Research Project

Project/Area Number 26670738
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Otorhinolaryngology
Research InstitutionThe University of Tokyo

Principal Investigator

Matsumoto Yu  東京大学, 医学部附属病院, 助教 (80548553)

Project Period (FY) 2014-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords生体イメージング / 耳科学
Outline of Final Research Achievements

Experimental procedures such as anesthesia, surgery, fixation and fluorescent staining were optimized. Calcium imaging of the hair cells was performed upon sound stimulation. Oxidative stress was also imaged upon direct administration of antimycin A.

Report

(3 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • Research Products

    (61 results)

All 2016 2015 2014 Other

All Journal Article (22 results) (of which Int'l Joint Research: 6 results,  Peer Reviewed: 21 results,  Open Access: 5 results,  Acknowledgement Compliant: 1 results) Presentation (37 results) (of which Int'l Joint Research: 3 results,  Invited: 6 results) Remarks (2 results)

  • [Journal Article] cRGD-installed polymeric micelles loading platinum anticancer drugs enable cooperative treatment against lymph node metastasis2016

    • Author(s)
      Jun Makino, Horacio Cabral, Yutaka Miura, Yu Matsumoto, Ming Wang, Hiroaki Kinoh, Yuki Mochida, Nobuhiro Nishiyama, Kazunori Kataoka
    • Journal Title

      Journal of Controlled Release

      Volume: 220 PartB Pages: 783-791

    • DOI

      10.1016/j.jconrel.2015.10.017

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Systemically Injectable Enzyme-Loaded Polyion Complex Vesicles as In Vivo Nanoreactors Functioning in Tumors.2016

    • Author(s)
      Anraku Y, Kishimura A, Kamiya M, Tanaka S, Nomoto T, Toh K, Matsumoto Y, Fukushima S, Sueyoshi D, Kano MR, Urano Y, Nishiyama N, Kataoka K.
    • Journal Title

      Angew Chem Int Ed Engl.

      Volume: 55 Issue: 2 Pages: 560-565

    • DOI

      10.1002/anie.201508339

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Enhanced efficacy against cervical carcinomas through polymeric micelles physically incorporating the proteasome inhibitor MG1322016

    • Author(s)
      Matsumoto Y, Miyamoto Y, Cabral H, Matsumoto Y, Nagasaka K, Nakagawa S, Yano T, Maeda D, Oda K, Kawana K, Nishiyama N, Kataoka K, Fujii T
    • Journal Title

      Cancer Sci

      Volume: 107 Issue: 6 Pages: 773

    • DOI

      10.1111/cas.12926

    • NAID

      120007089072

    • URL

      https://pure.teikyo.jp/en/publications/ba568e7f-01a0-47eb-a707-2c1b9629acb6

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Vascular bursts enhance permeability of tumour blood vessels and improve nanoparticle delivery2016

    • Author(s)
      Yu Matsumoto, Joseph W. Nichols, Kazuko Toh, Takahiro Nomoto, Horacio Cabral, Yutaka Miura, R. James Christie, Naoki Yamada, Tadayoshi Ogura, Mitsunobu R. Kano, Yasuhiro Matsumura, Nobuhiro Nishiyama, Tatsuya Yamasoba, You Han Bae, Kazunori Kataoka
    • Journal Title

      Nature Nanotechnology

      Volume: - Issue: 6 Pages: 533-538

    • DOI

      10.1038/nnano.2015.342

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Systemic delivery of siRNA by actively targeted polyion complex micelles for silencing the E6 and E7 human papillomavirus oncogenes2016

    • Author(s)
      Nishida H, Matsumoto Y, Kawana K, Christie RJ, Naito M, Kim BS, Toh K, Min HS, Yi Y, Matsumoto Y, Kim HJ, Miyata K, Taguchi A, Tomio K, Yamashita A, Inoue T, Nakamura H, Fujimoto A, Sato M, Yoshida M, Adachi K, Arimoto T, Wada-Hiraike O, Oda K, Nagamatsu T, Nishiyama N, Kataoka K, Osuga Y, Fujii T
    • Journal Title

      J Control Release

      Volume: 231 Pages: 29

    • DOI

      10.1016/j.jconrel.2016.03.016

    • URL

      https://pure.teikyo.jp/en/publications/1246fd42-3a7f-4b6e-b89e-7b96f138ec83

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Calcium phosphate-based organic-inorganic hybrid nanocarriers with pH-responsive on/off switch for photodynamic therapy2016

    • Author(s)
      T. Nomoto, S. Fukushima, M. Kumagai, K. Miyazaki, A. Inoue, P. Mi, Y. Maeda, K. Toh, Y. Matsumoto, Y. Morimoto, A. Kishimura, N. Nishiyama, K. Kataoka
    • Journal Title

      Biomater. Sci.

      Volume: 印刷中 Issue: 5 Pages: 826-838

    • DOI

      10.1039/c6bm00011h

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Analyzing Spatiotemporal Distribution of Uniquely Fluorescent Nanoparticles in Xenograft Tumors2016

    • Author(s)
      Stirland DL, Matsumoto Y, Toh K, Kataoka K, Bae YH
    • Journal Title

      J Control Release

      Volume: in press Pages: 38-44

    • DOI

      10.1016/j.jconrel.2016.02.016

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Design of high-performance anti-adhesion agent using injectable gel with an anti-oxidative stress function.2015

    • Author(s)
      Nakagawa H, Matsumoto Y, Matsumoto Y, Miwa Y, Nagasaki Y
    • Journal Title

      Biomaterials

      Volume: 69 Pages: 165-173

    • DOI

      10.1016/j.biomaterials.2015.08.018

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Ternary Polyplex Micelles with Peg Shells and Intermediate Barrier to Complexed DNA Cores for Efficient Systemic Gene Delivery2015

    • Author(s)
      Li J, Chen Q, Zha Z, Li H, Toh K, Dirisala A, Matsumoto Y, Osada K, Kataoka K, Ge Z
    • Journal Title

      J Control Release

      Volume: 2015 Pages: 77-87

    • DOI

      10.1016/j.jconrel.2015.04.024

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Density-Tunable Conjugation of Cyclic Rgd Ligands with Polyion Complex Vesicles for the Neovascular Imaging of Orthotopic Glioblastomas2015

    • Author(s)
      Kawamura W, Miura Y, Kokuryo D, Toh K, Yamada N, Nomoto T, Matsumoto Y, Sueyoshi D, Liu X, Aoki I, Kano MR, Nishiyama N, Saga T, Kishimura A, Kataoka K
    • Journal Title

      Science and Technology of Advanced Materials

      Volume: 16 Issue: 3 Pages: 035004-035004

    • DOI

      10.1088/1468-6996/16/3/035004

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Systemic Targeting of Lymph Node Metastasis through the Blood Vascular System by Using Size-Controlled Nanocarriers2015

    • Author(s)
      H. Cabral, J. Makino, Y. Matsumoto, P. Mi, H. Wu, T. Nomoto, K. Toh, N. Yamada, Y. Higuchi, S. Konishi, M.R. Kano, H. Nishihara, Y. Miura, N. Nishiyama, K. Kataoka
    • Journal Title

      ACS Nano

      Volume: Article ASAP Issue: 5 Pages: 4957-67

    • DOI

      10.1021/nn5070259

    • Related Report
      2015 Annual Research Report 2014 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Light-induced cytosolic activation of reduction-sensitive camptothecin-loaded polymeric micelles for spatiotemporally controlled in vivo chemotherapy2014

    • Author(s)
      H.-C. Yen, H. Cabral, P. Mi, K. Toh, Y. Matsumoto, X. Liu, H. Koori, A. Kim, K. Miyazaki, Y. Miura, N. Nishiyama, K. Kataoka
    • Journal Title

      ACS Nano

      Volume: 8 Issue: 11 Pages: 11591-11602

    • DOI

      10.1021/nn504836s

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] Polymeric micelles loaded with platinum anticancer drugs target preangiogenic micrometastatic niches associated with inflammation2014

    • Author(s)
      H. Wu, H. Cabral, K. Toh, P. Mi, Y.-C. Chen, Y. Matsumoto, N. Yamada, X. Liu, H. Kinoh, Y. Miura, M. R. Kano, H. Nishihara, N. Nishiyama, K. Kataoka
    • Journal Title

      J. Control. Release

      Volume: 189 Pages: 1-10

    • DOI

      10.1016/j.jconrel.2014.06.018

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] An injectable spheroid system with genetic modification for cell transplantation therapy2014

    • Author(s)
      Uchida S, ltaka K, Nomoto T, Endo T, Matsumoto Y, Ishii T, Kataoka K
    • Journal Title

      Biomaterials

      Volume: 35(8) Issue: 8 Pages: 2499-506

    • DOI

      10.1016/j.biomaterials.2013.12.012

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] Multicompartment micelles with adjustable poly (ethylene glycol) shell for efficient in vivo photodynamic therapy2014

    • Author(s)
      C. V. Synatschke, N. Nishiyama, et al.
    • Journal Title

      ACS Nano

      Volume: (in press)(印刷中)(掲載確定) Issue: 2 Pages: 1161-1172

    • DOI

      10.1021/nn4028294

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] Actively-targeted polyion complex micelles stabilized by cholesterol and disulfide cross-linking for systemic delivery of siRNA to solid tumors2014

    • Author(s)
      Y. Oe, R. J. Christie, M. Naito, S. A. Low, S. Fukushima, K. Toh, Y. Miura, Y. Matsumoto, N. Nishiyama, K. Miyata, K. Kataoka
    • Journal Title

      Biomaterials

      Volume: 35 Issue: 27 Pages: 7887-7895

    • DOI

      10.1016/j.biomaterials.2014.05.041

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] Aggregation Behavior of Cationic Nanohydrogel Particles in Human Blood Serum2014

    • Author(s)
      L. Nuhn, S. Gietzen, K. Mohr, K. Fischer, K. Toh, K. Miyata, Y. Matsumoto, K. Kataoka, M. Schmidt, R. Zentel
    • Journal Title

      Biomacromolecules

      Volume: Article ASAP Issue: 4 Pages: 1526-1533

    • DOI

      10.1021/bm500199h

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] Precise engineering of siRNA delivery vehicles to tumors using polyion complexes and gold nanoparticles2014

    • Author(s)
      H. -J. Kim, H. Takemoto, Y. Yi, M. Zheng, Y. Maeda, H. Chaya, K. Hayashi, P. Mi, F. Pittella, R. J. Christie, K. Toh, Y. Matsumoto, N. Nishiyama, K. Miyata, K. Kataoka
    • Journal Title

      ACS Nano

      Volume: 8 Issue: 9 Pages: 8979-8991

    • DOI

      10.1021/nn502125h

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Multifunctional polyion complex micelle featuring enhanced stability, targetability, and endosome escapability for systemic siRNA delivery to subcutaneous model of lung cancer2014

    • Author(s)
      Hyun Jin Kim, Takehiko Ishii, Meng Zheng, Sumiyo Watanabe, Kazuko Toh, Yu Matsumoto, Nobuhiro Nishiyama, Kanjiro Miyata, Kazunori Kataoka
    • Journal Title

      Drug Delivery and Translational Research

      Volume: 4 Issue: 1 Pages: 50-60

    • DOI

      10.1007/s13346-013-0175-6

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Targeted gene delivery by polyplex micelles with crowded PEG palisade and cRGD moiety for systemic treatment of pancreatic tumors2014

    • Author(s)
      Z. Ge, Q. Chen, K. Osada, X. Liu, T. A. Tockary, S. Uchida, A. Dirisala, T. Ishii, T. Nomoto, K. Toh, Y. Matsumoto, M. Oba, M. R. Kano, K. Itaka, K. Kataoka
    • Journal Title

      Biomaterials

      Volume: 35 Issue: 10 Pages: 3416-3426

    • DOI

      10.1016/j.biomaterials.2013.12.086

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] 症例をどうみるか 脳表ヘモジデリン沈着症による進行性感音難聴の1例2014

    • Author(s)
      久田真弓, 狩野章太郎, 松本有, 尾形エリカ, 赤松裕介, 山岨達也
    • Journal Title

      JOHNS

      Volume: 30 Pages: 667-669

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] 【ナノメディシンのための新しいドラックデリバリー】 生体内顕微鏡によるナノメディシンのリアルタイム観察2014

    • Author(s)
      野本貴大, 松本有
    • Journal Title

      BIO Clinica

      Volume: 29 Pages: 1165-1169

    • Related Report
      2014 Research-status Report
  • [Presentation] Tips and Tricks in Transcanal Endoscopic Ear Surgery2015

    • Author(s)
      Matsumoto Y
    • Organizer
      13th Japan-Taiwan Conference on Otolaryngology-Head and Neck Surgery
    • Place of Presentation
      Hitotsubashi Hall, National Center of Sciences, Tokyo, Japan
    • Year and Date
      2015-12-04
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Intravital Imaging of Drug Delivery Systems2015

    • Author(s)
      Matsumoto Y
    • Organizer
      2015 Conference on Developmental Biology Scientific & Drug Delivery System Program
    • Place of Presentation
      Academia Sinica, Taipei, Taiwan
    • Year and Date
      2015-11-10
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 高齢者の人工聴覚器(人工中耳・人工内耳)の適応・実施上の留意点2015

    • Author(s)
      松本 有
    • Organizer
      第25回日本耳科学会総会・学術講演会
    • Place of Presentation
      長崎ブリックホール、長崎県長崎市
    • Year and Date
      2015-10-09
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] Intravital Confocal / Two Photon Microscopy2015

    • Author(s)
      Matsumoto Y
    • Organizer
      NIS 8th Nikon Microscope Image Forum
    • Place of Presentation
      Haifeng International Hotel, Haidong City, Qinghai, China
    • Year and Date
      2015-07-28
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 生体イメージングのテクニックとドラッグデリバリーシステム開発への応用2015

    • Author(s)
      松本有
    • Organizer
      糖尿病研究ネットワークカンファレンス
    • Place of Presentation
      アストラゼネカ株式会社東京支社、東京都中央区
    • Year and Date
      2015-03-25
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] Ligand density effect on selective delivery in brain parenchyma through blood-brain barrier of glucose-linked polyion complex micelle system2014

    • Author(s)
      Fukusato Y, Anraku Y, Mizoguchi A, Ishii T, Matsumoto Y, Toh K, Kuwahara H, Yokota T, Kataoka K
    • Organizer
      The 10th International Polymer Conference IPC2014
    • Place of Presentation
      International Congress Center, Tsukuba, Ibaraki
    • Year and Date
      2014-12-05
    • Related Report
      2014 Research-status Report
  • [Presentation] Polymeric micelles loaded with platinum anticancer drugs target preangiogenic micrometastatic niches associated with inflammation2014

    • Author(s)
      Wu H, Cabral H, Toh K, Mi P, Matsumoto Y, Ahn JY, Kinoh H, Nishiyama N, Miura Y, Kataoka K
    • Organizer
      The 10th International Polymer Conference IPC2014
    • Place of Presentation
      International Congress Center, Tsukuba, Ibaraki
    • Year and Date
      2014-12-03
    • Related Report
      2014 Research-status Report
  • [Presentation] 核酸創薬とドラッグデリバリーシステムの革新による認知症の遺伝子治療への道 リガンド搭載高分子ミセル型ナノキャリアを用いた組織特異的核酸デリバリー2014

    • Author(s)
      宮田完二郎, 安楽泰孝, 福里優, 溝口明祐, 石井武彦, 藤加珠子, 松本有, 桑原宏哉, 横田隆徳, 片岡一則
    • Organizer
      第33回日本認知症学会学術集会
    • Place of Presentation
      パシフィコ横浜会議センター、神奈川県横浜市
    • Year and Date
      2014-11-29
    • Related Report
      2014 Research-status Report
  • [Presentation] 難聴患者の次世代シークエンサーによる遺伝子変異エクソーム解析2014

    • Author(s)
      坂田阿希, 樫尾明憲, 松本有, 狩野章太郎, 柿木章伸, 尾形エリカ, 赤松裕介, 山岨達也
    • Organizer
      第59回日本聴覚医学会総会・学術講演会
    • Place of Presentation
      海峡メッセ下関、山口県下関市
    • Year and Date
      2014-11-27
    • Related Report
      2014 Research-status Report
  • [Presentation] 血液脳関門を突破し脳神経系細胞に薬剤を送達する高分子ミセルの開発(Poster)2014

    • Author(s)
      福里優, 安楽泰孝, 溝口明宏, 石井武彦, 松本有, 藤加珠子, 桑原宏哉, 新田佳子, 横田隆徳, 片岡一則
    • Organizer
      第36回日本バイオマテリアル学会
    • Place of Presentation
      タワーホール船堀、東京都江戸川区
    • Year and Date
      2014-11-17
    • Related Report
      2014 Research-status Report
  • [Presentation] リンパ節転移がん治療のための高分子ミセル型DDSの効果的なデザインに関する研究2014

    • Author(s)
      牧野惇, Cabral H, 三浦裕, 松本有, 喜納宏昭, 西山伸宏, 片岡一則
    • Organizer
      第36回日本バイオマテリアル学会
    • Place of Presentation
      タワーホール船堀、東京都江戸川区
    • Year and Date
      2014-11-17
    • Related Report
      2014 Research-status Report
  • [Presentation] 血液脳関門を突破し脳神経系細胞に薬剤を送達する高分子ミセルの開発(Oral)2014

    • Author(s)
      安楽泰孝, 福里優, 溝口明宏, 石井武彦, 松本有, 藤加珠子, 桑原宏哉, 新田佳子, 横田隆徳, 片岡一則
    • Organizer
      第36回日本バイオマテリアル学会
    • Place of Presentation
      タワーホール船堀、東京都江戸川区
    • Year and Date
      2014-11-17
    • Related Report
      2014 Research-status Report
  • [Presentation] 加振器を使用したマウス前庭機能検査システムの構築2014

    • Author(s)
      鴨頭 輝, 岩崎 真, 木下 淳, 藤本 千, 松本 有, 狩野 章, 山岨 達
    • Organizer
      第73回日本めまい平衡医学会総会・学術講演会
    • Place of Presentation
      パシフィコ横浜、神奈川県横浜市
    • Year and Date
      2014-11-07
    • Related Report
      2014 Research-status Report
  • [Presentation] 前庭症状を主訴とした症例での簡易温度刺激検査の年代別検討2014

    • Author(s)
      畑 裕子, 山崎 葉, 堤内 亮, 山本 沙, 崎谷 恵, 一瀬 和, 馬場 美, 松本 有, 小嶋 康, 井之口 豪, 藤田 岳, 奥野 妙
    • Organizer
      第73回日本めまい平衡医学会総会・学術講演会
    • Place of Presentation
      パシフィコ横浜、神奈川県横浜市
    • Year and Date
      2014-11-07
    • Related Report
      2014 Research-status Report
  • [Presentation] POU3F4遺伝子変異およびIP type IIIを伴う両側高度感音難聴に対し人工内耳手術を施行した1例2014

    • Author(s)
      渋谷幸彦, 山岨達也, 岩崎真一, 柿木章伸, 坂本幸士, 狩野章太郎, 松本有, 樫尾明憲, 尾形エリカ, 赤松裕介
    • Organizer
      第24回日本日本耳科学会総会・学術講演会
    • Place of Presentation
      朱鷺メッセ、新潟県新潟市
    • Year and Date
      2014-10-15
    • Related Report
      2014 Research-status Report
  • [Presentation] 人工内耳手術を施行したWaardenburg症候群5症例の検討2014

    • Author(s)
      小山一, 樫尾明憲, 尾形エリカ, 赤松裕介, 松本有, 狩野章太郎, 坂本幸士, 岩崎真一, 柿木章伸, 山岨達也
    • Organizer
      第24回日本日本耳科学会総会・学術講演会
    • Place of Presentation
      朱鷺メッセ、新潟県新潟市
    • Year and Date
      2014-10-15
    • Related Report
      2014 Research-status Report
  • [Presentation] Systemic targeting of lymph node metastasis by controlled design of drug-loaded polymeric micelles (Oral)2014

    • Author(s)
      Makino J, Cabral H, Miura Y, Matsumoto Y, Kinoh H, Nishiyama N, Kataoka K
    • Organizer
      12th International Nanomedicine and Drug Delivery Symposium (NanoDDS'14)
    • Place of Presentation
      UNC Eshelman School of Pharmacy and Duke University, NC, USA
    • Year and Date
      2014-10-08
    • Related Report
      2014 Research-status Report
  • [Presentation] Systemic targeting of lymph node metastasis by controlled design of drug-loaded polymeric micelles (Poster)2014

    • Author(s)
      Makino J, Cabral H, Miura Y, Matsumoto Y, Kinoh H, Nishiyama N, Kataoka K
    • Organizer
      12th International Nanomedicine and Drug Delivery Symposium (NanoDDS'14)
    • Place of Presentation
      UNC Eshelman School of Pharmacy and Duke University, NC, USA
    • Year and Date
      2014-10-07
    • Related Report
      2014 Research-status Report
  • [Presentation] アリナミンテストの新たな意義 マウスアリナミンテストからのメッセージ2014

    • Author(s)
      菊田 周, 松本 有, 坂本 幸, 岩村 均, 西嶌 大, 平野 真, 近藤 健, 山岨 達
    • Organizer
      第53回日本鼻科学会総会・学術講演会
    • Place of Presentation
      ナレッジキャピタル コングレコンベンションセンター、大阪市北区
    • Year and Date
      2014-09-25
    • Related Report
      2014 Research-status Report
  • [Presentation] 血液脳関門を効率的に通過する高分子ミセルの創製~リガンド密度効果について~2014

    • Author(s)
      福里優, 安楽泰孝, 溝口明宏, 石井武彦, 松本有, 藤加珠子, 桑原宏哉, 新田佳子, 横田隆徳, 片岡一則
    • Organizer
      第63回高分子討論会
    • Place of Presentation
      長崎大学文教キャンパス、長崎県長崎市
    • Year and Date
      2014-09-25
    • Related Report
      2014 Research-status Report
  • [Presentation] 腫瘍でクスリを「作る」酵素封入PICsomeシステムの開発2014

    • Author(s)
      安楽泰孝, Xiao L, Cabral H, 末吉大輝, 福島重人, 松本有, 藤加珠子, 神谷真子, 浦野泰照, 岸村顕広, 西山伸宏, 片岡一則
    • Organizer
      第63回高分子討論会
    • Place of Presentation
      長崎大学文教キャンパス、長崎県長崎市
    • Year and Date
      2014-09-25
    • Related Report
      2014 Research-status Report
  • [Presentation] 血液脳関門を効率的に通過する高分子ミセルシステムの構築2014

    • Author(s)
      安楽泰孝, 福里優, 溝口明宏, 石井武彦, 松本有, 藤加珠子, 桑原宏哉, 新田佳子, 横田隆徳, 片岡一則
    • Organizer
      アンチセンス・遺伝子・デリバリーシンポジウム2014
    • Place of Presentation
      東京医科歯科大学 M&Dタワー、東京都文京区
    • Year and Date
      2014-09-08
    • Related Report
      2014 Research-status Report
  • [Presentation] Intravital Imaging of Drug Delivery Systems2014

    • Author(s)
      Matsumoto, Y.
    • Organizer
      ニコン アジア・オセアニア・中近東特約店会議
    • Place of Presentation
      ニコン大井ウエストビル、東京都品川区
    • Year and Date
      2014-09-03
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] Toolbox of differently sized and labeled PMMA nanoparticles for cell studies2014

    • Author(s)
      Schubert S, Vollrath A, Traeger A, Pretzel D, Pietsch C, Nomoto T, Matsumoto Y, Kataoka K, Schubert US
    • Organizer
      248th American Chemical Society (ACS) National Meeting & Exposition
    • Place of Presentation
      Moscone Center, San Francisco, CA, USA
    • Year and Date
      2014-08-11
    • Related Report
      2014 Research-status Report
  • [Presentation] 効率的に血液脳関門を通過する高分子ミセルの開発2014

    • Author(s)
      安楽泰孝, 福里優, 溝口明祐, 石井武彦, 藤加珠子, 松本有, 桑原宏哉, 横田隆徳, 片岡一則
    • Organizer
      第30回日本DDS学会学術集会
    • Place of Presentation
      慶應義塾大学芝共立キャンパス、東京都港区
    • Year and Date
      2014-07-31
    • Related Report
      2014 Research-status Report
  • [Presentation] リンパ節転移がんのcRGD介在ターゲティングによる薬剤内包高分子ミセルの活性の向上2014

    • Author(s)
      牧野惇, Cabral H, 三浦裕, 松本有, 西山伸宏, 片岡一則
    • Organizer
      第30回日本DDS学会学術集会
    • Place of Presentation
      慶應義塾大学芝共立キャンパス、東京都港区
    • Year and Date
      2014-07-30
    • Related Report
      2014 Research-status Report
  • [Presentation] Polymeric micelles loaded with platinum anticancer drugs target preangiogenic micrometastatic niches associated with inflammation2014

    • Author(s)
      Wu H, Cabral H, 藤加珠子, Mi P, Chen YC, 松本有, 山田直生, Liu X, 喜納宏昭, 三浦裕, 狩野光伸, 西原寛, 西山伸宏, 片岡一則
    • Organizer
      第30回日本DDS学会学術集会
    • Place of Presentation
      慶應義塾大学芝共立キャンパス、東京都港区
    • Year and Date
      2014-07-30
    • Related Report
      2014 Research-status Report
  • [Presentation] 高効率に脳血液関門を通過するスマートナノマシンの開発2014

    • Author(s)
      安楽泰孝, 福里優, 溝口明祐, 石井武彦, 藤加珠子, 松本有, 桑原宏哉, 横田隆徳, 片岡一則
    • Organizer
      第63回高分子学会年次大会
    • Place of Presentation
      名古屋国際会議場、愛知県名古屋市
    • Year and Date
      2014-05-29
    • Related Report
      2014 Research-status Report
  • [Presentation] PEG growdedness on polyplex micelle gene carrier determining its shape and blood circulation profile2014

    • Author(s)
      Tockary T, Osada K, Chen Q, Machitani K, Dirisala A, Uchida S, Toh K, Nomoto T, Matsumoto Y, Kataoka K
    • Organizer
      第63回高分子学会年次大会
    • Place of Presentation
      名古屋国際会議場、愛知県名古屋市
    • Year and Date
      2014-05-28
    • Related Report
      2014 Research-status Report
  • [Presentation] 生体における抗酸化能の可視化2014

    • Author(s)
      松本有, 狩野章太郎, 吉川弥生, 山岨達也
    • Organizer
      第115回日本耳鼻咽喉科学会・学術講演会
    • Place of Presentation
      ヒルトン福岡市ーホーク、福岡県福岡市
    • Year and Date
      2014-05-16
    • Related Report
      2014 Research-status Report
  • [Presentation] 前庭症状を主訴とした症例の年代別特徴について 第2報2014

    • Author(s)
      畑裕子, 堤内亮博, 山本沙織, 一瀬和美, 松本有, 藤田岳, 小嶋康隆, 桑内麻也子, 宇野真莉子, 山崎葉子, 栗田宣彦, 奥野妙子
    • Organizer
      第115回日本耳鼻咽喉科学会・学術講演会
    • Place of Presentation
      ヒルトン福岡市ーホーク、福岡県福岡市
    • Year and Date
      2014-05-15
    • Related Report
      2014 Research-status Report
  • [Presentation] アリナミンテストの結果に対する病態に基づいた新たな解釈2014

    • Author(s)
      菊田周, 松本有, 坂本幸士, 近藤健二, 上羽瑠美, 岩村均, 籠谷領二, 西嶌大宣, 鈴川佳吾, 平野真希子, 山岨達也
    • Organizer
      第115回日本耳鼻咽喉科学会・学術講演会
    • Place of Presentation
      ヒルトン福岡市ーホーク、福岡県福岡市
    • Year and Date
      2014-05-14
    • Related Report
      2014 Research-status Report
  • [Presentation] Low pass filterを介した日本語音声の聴取成績の検討2014

    • Author(s)
      浦中司, 村田麻里, 尾形エリカ, 赤松祐介, 松本有, 狩野章太郎, 坂本幸士, 柿木彰伸, 岩崎真一, 山岨達也
    • Organizer
      第115回日本耳鼻咽喉科学会・学術講演会
    • Place of Presentation
      ヒルトン福岡市ーホーク、福岡県福岡市
    • Year and Date
      2014-05-14
    • Related Report
      2014 Research-status Report
  • [Presentation] 日本語版UW-CAMP音楽聞き取り評価テスト(J-CAMP)の作成2014

    • Author(s)
      樫尾明憲, 尾形エリカ, 赤松裕介, 柴崎仁志, 岸本めぐみ, 松本有, 坂本幸士, 狩野章太郎, 柿木章伸, 岩崎真一, 山岨達也
    • Organizer
      第115回日本耳鼻咽喉科学会・学術講演会
    • Place of Presentation
      ヒルトン福岡市ーホーク、福岡県福岡市
    • Year and Date
      2014-05-14
    • Related Report
      2014 Research-status Report
  • [Presentation] 耳硬化症の難聴発症と側頭骨CT所見2014

    • Author(s)
      奥野妙子, 小嶋康隆, 畑裕子, 松本有, 栗田宣彦, 堤内亮博, 山本沙織, 一瀬和美
    • Organizer
      第115回日本耳鼻咽喉科学会・学術講演会
    • Place of Presentation
      ヒルトン福岡市ーホーク、福岡県福岡市
    • Year and Date
      2014-05-14
    • Related Report
      2014 Research-status Report
  • [Presentation] 中耳真珠腫進展度分類2010改訂案中のアブミ骨病変の程度に基づいた真珠腫性中耳炎自験例の検討2014

    • Author(s)
      堤内亮博, 畑裕子, 松本有, 小嶋康隆, 藤田岳, 一瀬和美, 山本沙織, 奥野妙子
    • Organizer
      第115回日本耳鼻咽喉科学会・学術講演会
    • Place of Presentation
      ヒルトン福岡市ーホーク、福岡県福岡市
    • Year and Date
      2014-05-14
    • Related Report
      2014 Research-status Report
  • [Presentation] 当科における高齢難聴者の人工内耳埋込み術後の聴取成績について2014

    • Author(s)
      内山美智子, 狩野章太郎, 尾形エリカ, 赤松裕介, 樫尾明憲, 松本有, 坂本幸士, 柿木章伸, 岩崎真一, 山岨達也
    • Organizer
      第115回日本耳鼻咽喉科学会・学術講演会
    • Place of Presentation
      ヒルトン福岡市ーホーク、福岡県福岡市
    • Year and Date
      2014-05-14
    • Related Report
      2014 Research-status Report
  • [Remarks] 片岡研究室

    • URL

      http://www.bmw.t.u-tokyo.ac.jp

    • Related Report
      2014 Research-status Report
  • [Remarks] 東京大学医学部耳鼻咽喉科学教室

    • URL

      http://www.h.u-tokyo.ac.jp/orl/

    • Related Report
      2014 Research-status Report

URL: 

Published: 2014-04-04   Modified: 2017-05-10  

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