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The excessive inspiration negative pressure of upper airway ventilation obstructed children makes mandible retreat -Using fluid structure interaction analysis

Research Project

Project/Area Number 26670889
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Orthodontics/Pediatric dentistry
Research InstitutionKagoshima University

Principal Investigator

Yamasaki Youichi  鹿児島大学, 医歯学域歯学系, 教授 (30200645)

Co-Investigator(Kenkyū-buntansha) IWASAKI Tomonori  鹿児島大学, 医歯学域歯学系, 准教授 (10264433)
KAJI Tatsuru  鹿児島大学, 医歯学域医学系, 准教授 (50315420)
HARADA Mizue  鹿児島大学, 医歯学域医学系, 助教 (20585103)
早崎 治明  新潟大学, 医歯学系, 教授 (60238095)
齊藤 一誠  新潟大学, 医歯学系, 准教授 (90404540)
Co-Investigator(Renkei-kenkyūsha) KANOMI Ryuzou  鹿児島大学, 医歯学総合研究科, 客員研究員 (70411444)
Project Period (FY) 2014-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2015: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2014: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
Keywordsairway pressure / 気道 / Class II / 下顎 / 呼吸 / 下顎後退咬合 / 流体解析
Outline of Final Research Achievements

This study examined the influence of the negative pressure of the airway on mandibular retraction during inspiration of children with nasal obstruction.
Sixty-two children were divided into Class I, II, and III groups. Airflow pressure was simulated using computational fluid dynamics to calculate nasal resistance and airway pressure during inspiration and expiration. Nasal resistance of the Class II group was significantly higher than that of the other two groups, and oropharyngeal airway inspiration pressure in the Class II (-247.64 Pa) group was larger than that in the Class I (-43.51 Pa) and Class III (-31.81 Pa) groups (P < 0.001). Airway inspiration-expiration pressure difference in the Class II (-27.38 Pa) group was larger than that in the Class I (-5.17 Pa) and Class III (0.68 Pa) groups (P = 0.006). Large negative inspiratory airway pressure due to nasal obstruction in children with Class II malocclusion may be related to their retrognathia.

Report

(3 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • Research Products

    (13 results)

All 2016 2015 2014 Other

All Int'l Joint Research (1 results) Journal Article (5 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 5 results,  Open Access: 3 results) Presentation (3 results) (of which Int'l Joint Research: 1 results,  Invited: 2 results) Book (3 results) Patent(Industrial Property Rights) (1 results) (of which Overseas: 1 results)

  • [Int'l Joint Research] Stanford University(米国)

    • Related Report
      2015 Annual Research Report
  • [Journal Article] Efficacy of Maxillomandibular Advancement Examined with Drug-Induced Sleep Endoscopy and Computational Fluid Dynamics Airflow Modeling.2016

    • Author(s)
      Liu SY, Huon LK, Iwasaki T, Yoon A, Riley R, Powell N, Torre C, Capasso R
    • Journal Title

      Otolaryngol Head Neck Surg.

      Volume: 151 Issue: 1 Pages: 189-195

    • DOI

      10.1177/0194599815611603

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Simultaneous Evaluation of Three-Dimensional2016

    • Author(s)
      Ken Morizono1, Yoshihiko Takemoto, Emi Inada, Daisuke Murakami, Issei Saitoh, Hideo Sato, Tomonori Iwasaki, Youichi Yamasaki
    • Journal Title

      International Journal of Dentistry and Oral Health

      Volume: 2 Issue: 2 Pages: 1-6

    • DOI

      10.16966/2378-7090.169

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 小児期の上気道通気障害がもたらす顎顔面歯列咬合形態への影響と小児歯科からの睡眠医療への貢献2016

    • Author(s)
      岩崎智憲
    • Journal Title

      小児歯科学雑誌

      Volume: 54 Pages: 1-8

    • NAID

      130005451061

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The effect of rapid maxillary expansion on pharyngeal airway pressure during inspiration evaluated using computational fluid dynamics2014

    • Author(s)
      Iwasaki T, Takemoto Y, Inada E, Sato H, Saitoh I, Kakuno E, Kanomi R, Yamasaki Y
    • Journal Title

      International Journal of Pediatric Otorhinolaryngology

      Volume: 56(12) Issue: 8 Pages: 1258-1264

    • DOI

      10.1016/j.ijporl.2014.05.004

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Three-dimensional cone-beam computed tomography analysis of enlargement of the pharyngeal airway by the Herbst appliance2014

    • Author(s)
      Iwasaki T, Takemoto Y, Inada E, Sato H, Suga H, Saitoh I, Kakuno E, Kanomi R, Yamasaki Y
    • Journal Title

      American Journal of Orthodontics & Dentofacial Orthopedics

      Volume: 1 Issue: 6 Pages: 1-1

    • DOI

      10.1016/j.ajodo.2014.08.017

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] 小児期の上気道通気障害がもたらす顎顔面歯列咬合形態への影響と 小児歯科からの睡眠医療への貢献2016

    • Author(s)
      岩崎智憲
    • Organizer
      第52回日本小児歯科学会
    • Place of Presentation
      広島国際会議場(広島県広島市)
    • Year and Date
      2016-05-22
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] Contemporary approch of airway problems in pediatric dentistry2016

    • Author(s)
      Yamasaki Y
    • Organizer
      KPPIKG2016
    • Place of Presentation
      Jakarta Convention Center - Indonesia
    • Year and Date
      2016-02-24
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 上気道通気状態が小児の前後的顎間関係に及ぼす影響 -吸気と呼気の流体力学的研究-2014

    • Author(s)
      岩崎智憲,武元嘉彦,稲田絵美,齊藤一誠,覚野恵梨子,嘉ノ海龍三,早崎治明,山崎要一,
    • Organizer
      第52回日本小児歯科学会大会
    • Place of Presentation
      東京(品川区立総合区民会館)
    • Year and Date
      2014-05-16 – 2014-05-17
    • Related Report
      2014 Research-status Report
  • [Book] 小児歯科臨床7月号2015

    • Author(s)
      岩崎智憲
    • Total Pages
      9
    • Publisher
      東京臨床出版
    • Related Report
      2015 Annual Research Report
  • [Book] 小児歯科臨床8月号2015

    • Author(s)
      岩崎智憲
    • Total Pages
      6
    • Publisher
      東京臨床出版
    • Related Report
      2015 Annual Research Report
  • [Book] 子どもの患者の治療・対応に上手くなろう!2015

    • Author(s)
      岩崎智憲
    • Total Pages
      6
    • Publisher
      ヒョーロン・パブリシャーズ
    • Related Report
      2015 Annual Research Report
  • [Patent(Industrial Property Rights)] 顎顔面部の流体構造連成解析を用いた気道通気状態解析システム2015

    • Inventor(s)
      岩崎智憲
    • Industrial Property Rights Holder
      岩崎智憲
    • Industrial Property Rights Type
      特許
    • Filing Date
      2015-07-08
    • Related Report
      2015 Annual Research Report
    • Overseas

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Published: 2014-04-04   Modified: 2022-01-27  

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