| Budget Amount *help |
¥23,790,000 (Direct Cost: ¥18,300,000、Indirect Cost: ¥5,490,000)
Fiscal Year 2017: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2016: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2015: ¥6,240,000 (Direct Cost: ¥4,800,000、Indirect Cost: ¥1,440,000)
Fiscal Year 2014: ¥8,190,000 (Direct Cost: ¥6,300,000、Indirect Cost: ¥1,890,000)
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| Outline of Final Research Achievements |
Intercellular interaction is fundamental phenomenon which plays an important role in various biological events such as development, immunological reaction, and cancer metastasis. In this project, we synthesized zipper-like molecules based of poly(ethylene glycol)-conjugated lipid, which are amphiphilic polymers, and induced homogeneous and heterogeneous cell-cell attachment, and examined the possibility of inducing the intercellular interaction. And based on the conventional 2-D cell culture methods, we succeeded in the creation of new zipper-like molecules. These molecules are useful for the new research area “3-D intercellular interaction”.
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