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Effects of exercise and horticultural intervention on the brain and mental health in older adults with depressive symptoms and memory problems

Research Project

Project/Area Number 26702033
Research Category

Grant-in-Aid for Young Scientists (A)

Allocation TypePartial Multi-year Fund
Research Field Applied health science
Research InstitutionKagoshima University (2017)
National Center for Geriatrics and Gerontology (2014-2016)

Principal Investigator

MAKIZAKO Hyuma  鹿児島大学, 医歯学域医学系, 教授 (70510303)

Research Collaborator SHIMADA Hiroyuki  
DOI Takehiko  
LEE Sangyoon  
Tsutsumimoto Kota  
NAKAKUBO Sho  
HOTTA Ryo  
MAKINO Keitaro  
Project Period (FY) 2014-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥23,530,000 (Direct Cost: ¥18,100,000、Indirect Cost: ¥5,430,000)
Fiscal Year 2017: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2016: ¥8,450,000 (Direct Cost: ¥6,500,000、Indirect Cost: ¥1,950,000)
Fiscal Year 2015: ¥9,750,000 (Direct Cost: ¥7,500,000、Indirect Cost: ¥2,250,000)
Fiscal Year 2014: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Keywords認知科学 / 脳・神経 / 健康科学 / 老化
Outline of Final Research Achievements

Among 202 community-dwelling elderly, 97 (48%) answered having specific daily activities to maintain their brain health. Participants with specific daily activities for brain health showed better performance in memory and processing speed tasks than those without. Older women with mild cognitive impairment (n = 56) who had routine gardening activities demonstrated increasing brain blood flow during verbal fluency tasks, while those without gardening activity showed fewer brain blood flow. The intervention effects of exercise and gardening activities on elderly subjects (n = 89) exhibiting depressive symptoms and mild memory loss were investigated. As a result of a simple comparison that refers to the Control Group, logical memory performance and the distance covered in a two-minute walk showed significant improvement in the Exercise Group. No items were observed showing significant improvements in the comparison between the Gardening Group and the Control Group.

Report

(5 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Annual Research Report
  • 2015 Annual Research Report
  • 2014 Annual Research Report
  • Research Products

    (24 results)

All 2018 2017 2016 2015 2014 Other

All Journal Article (9 results) (of which Int'l Joint Research: 2 results,  Peer Reviewed: 8 results,  Open Access: 3 results,  Acknowledgement Compliant: 2 results) Presentation (9 results) (of which Int'l Joint Research: 2 results,  Invited: 4 results) Book (3 results) Remarks (3 results)

  • [Journal Article] 認知症予防・転倒予防のための具体的な運動指導方法2017

    • Author(s)
      牧迫飛雄馬
    • Journal Title

      臨床スポーツ医学

      Volume: 34 Pages: 70-75

    • Related Report
      2016 Annual Research Report
  • [Journal Article] Comorbid mild cognitive impairment and depressive symptoms predict future dementia in community older adults: a 24-month follow-up longitudinal study.2016

    • Author(s)
      Makizako H, Shimada H, Doi T, Tsutsumimoto K, Hotta R, Nakakubo S, Makino K, Suzuki T.
    • Journal Title

      J Alzheimers Dis

      Volume: 54 Issue: 4 Pages: 1473-1482

    • DOI

      10.3233/jad-160244

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Effects of exercise and horticultural intervention on the brain and mental health in older adults with depressive symptoms and memory problems: study protocol for a randomized controlled trial2015

    • Author(s)
      Makizako H, Tsutsumimoto K, Doi T, Hotta R, Nakakubo S, Liu-Ambrose T, Shimada H
    • Journal Title

      Trials

      Volume: 16 Issue: 1 Pages: 499-499

    • DOI

      10.1186/s13063-015-1032-3

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Social frailty in community-dwelling older adults as a risk factor for disability2015

    • Author(s)
      Makizako H, Shimada H, Tsutsumimoto K, Lee S, Doi T, Nakakubo S, Hotta R, Suzuki T
    • Journal Title

      J Am Med Dir Assoc

      Volume: 16 Issue: 11 Pages: 1003.e7-1003.e11

    • DOI

      10.1016/j.jamda.2015.08.023

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Onset of disability by mild cognitive impairment subtype among community-dwelling older adults in Japan.2015

    • Author(s)
      Makizako H, Shimada H, Doi T, Tsutsumimoto K, Lee S, Suzuki T.
    • Journal Title

      J Am Geriatr Soc

      Volume: 印刷中

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Incidence of disability in frail older persons with or without slow walking speed.2015

    • Author(s)
      Shimada H, Makizako H, Doi T, Tsutsumimoto K, Suzuki T.
    • Journal Title

      J Am Med Dir Assoc

      Volume: 印刷中 Issue: 8 Pages: 690-696

    • DOI

      10.1016/j.jamda.2015.03.019

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Cognitive Functioning and Walking Speed in Older Adults as Predictors of Limitations in Self-Reported Instrumental Activity of Daily Living: Prospective Findings from the Obu Study of Health Promotion for the Elderly.2015

    • Author(s)
      Makizako H, Shimada H, Doi T, Tsutsumimoto K, Lee S, Hotta R, Nakakubo S, Harada K, Lee S, Bae S, Harada K, Suzuki T.
    • Journal Title

      Int J Environ Res Public Health

      Volume: 12(3) Issue: 3 Pages: 3002-13

    • DOI

      10.3390/ijerph120303002

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Cigarette smoking and cognitive health in elderly Japanese.2015

    • Author(s)
      Hotta R, Doi T, Shimada H, Makizako H, Yoshida D, Anan Y, Tsutsumimoto K, Uemura K, Park H, Suzuki T.
    • Journal Title

      Am J Health Behav.

      Volume: 39(3) Issue: 3 Pages: 294-300

    • DOI

      10.5993/ajhb.39.3.1

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Physical frailty predicts incident depressive symptoms in elderly people: prospective findings from the Obu Study of Health Promotion for the Elderly.2015

    • Author(s)
      Makizako H, Shimada H, Doi T, Yoshida D, Anan Y, Tsutsumimoto K, Uemura K, Liu-Ambrose T, Park H, Lee S, Suzuki T.
    • Journal Title

      J Am Med Dir Assoc.

      Volume: 16(3) Issue: 3 Pages: 194-9

    • DOI

      10.1016/j.jamda.2014.08.017

    • Related Report
      2014 Annual Research Report
    • Peer Reviewed
  • [Presentation] うつ徴候および軽度記憶低下を有する高齢者に対する運動および菜園介入によるランダム化比較試験2018

    • Author(s)
      牧迫飛雄馬、土井剛彦、牧野圭太郎、堤本広大、中窪翔、島田裕之
    • Organizer
      第60回日本老年医学会学術集会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Physical, cognitive, and social activities for frailty prevention2017

    • Author(s)
      Hyuma Makizako, Hiroyuki Shimada, Takehiko Doi, Kota Tsutsumimoto, Ryo Hotta, Sho Nakakubo, Keitaro Makino
    • Organizer
      3RD ASIAN CONFERENCE FOR FRAILTY AND SARCOPENIA
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Comorbid mild cognitive impairment and depressive symptoms predict future dementia in community older adults: a 24-month follow-up longitudinal study2016

    • Author(s)
      Makizako H, Shimada H, Doi T, Tsutsumimoto K, Hotta R, Nakakubo S, Makino K, Suzuki T
    • Organizer
      2016 Alzheimer's Association International Conference
    • Place of Presentation
      Toronto, Canada
    • Year and Date
      2016-07-24
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 地域在住高齢者における脳の健康維持のための活動と認知機能との関連2015

    • Author(s)
      牧迫飛雄馬,島田裕之,土井剛彦,堤本広大,上村一貴,李相侖
    • Organizer
      第2回日本地域理学療法学会学術集会
    • Place of Presentation
      千葉
    • Year and Date
      2015-12-13
    • Related Report
      2015 Annual Research Report
  • [Presentation] 地域における高齢者機能健診からの理学療法へのメッセージと地域資源の活性を促進する新たな展開2015

    • Author(s)
      牧迫飛雄馬
    • Organizer
      第50回日本理学療法学術大会
    • Place of Presentation
      東京
    • Year and Date
      2015-06-05
    • Related Report
      2015 Annual Research Report
  • [Presentation] 運動介入としてのデュアルタスクの可能性2014

    • Author(s)
      牧迫飛雄馬
    • Organizer
      第1回日本基礎理学療法学会学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2014-11-16
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] Exercise and brain health in older adults with mild cognitive impairment. 17th World Congress of Psychophysiology2014

    • Author(s)
      Makizako H
    • Organizer
      17th World Congress of Psychophysiology
    • Place of Presentation
      Hiroshima
    • Year and Date
      2014-09-24
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Presentation] 軽度認知障害を有する高齢者における身体活動,海馬容量,記憶の相互関連性2014

    • Author(s)
      牧迫飛雄馬,Teresa Liu-Ambrose,島田裕之,土井剛彦,朴眩泰,堤本広大,上村一貴,鈴木隆雄
    • Organizer
      第49回日本理学療法学術集会
    • Place of Presentation
      横浜
    • Year and Date
      2014-05-30
    • Related Report
      2014 Annual Research Report
  • [Presentation] 認知症予防のための理学療法2014

    • Author(s)
      牧迫飛雄馬
    • Organizer
      第69回日本理学療法科学学会
    • Place of Presentation
      埼玉
    • Year and Date
      2014-04-20
    • Related Report
      2014 Annual Research Report
    • Invited
  • [Book] 基礎からわかる軽度認知障害(MCI)―効果的な認知症予防を目指して―2015

    • Author(s)
      牧迫飛雄馬(鈴木隆雄(監),島田裕之(編))
    • Total Pages
      11
    • Publisher
      医学書院
    • Related Report
      2014 Annual Research Report
  • [Book] 理学療法士になるには2014

    • Author(s)
      牧迫飛雄馬
    • Total Pages
      7
    • Publisher
      株式会社ぺりかん社
    • Related Report
      2014 Annual Research Report
  • [Book] サルコペニアと運動-エビデンスと実践-2014

    • Author(s)
      牧迫飛雄馬(島田裕之(編))
    • Total Pages
      7
    • Publisher
      医歯薬出版
    • Related Report
      2014 Annual Research Report
  • [Remarks] 国立長寿医療研究センター予防老年学研究部

    • URL

      http://www.ncgg.go.jp/cgss/department/cre/

    • Related Report
      2016 Annual Research Report
  • [Remarks] 国立長寿医療研究センター 予防老年学研究部

    • URL

      http://www.ncgg.go.jp/cgss/department/cre/

    • Related Report
      2015 Annual Research Report
  • [Remarks] 国立長寿医療研究センター予防老年学研究部

    • URL

      http://www.ncgg.go.jp/department/cre/index.html

    • Related Report
      2014 Annual Research Report

URL: 

Published: 2014-04-04   Modified: 2019-03-29  

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