Neuronal population activity of visuo-motor transformation in the superior colliculus
Project/Area Number |
26750382
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Research Category |
Grant-in-Aid for Young Scientists (B)
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Allocation Type | Multi-year Fund |
Research Field |
Brain biometrics
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Research Institution | National Institute for Physiological Sciences |
Principal Investigator |
KASAI Masatoshi 生理学研究所, 発達生理学研究系, 特別協力研究員 (70625269)
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Project Period (FY) |
2014-04-01 – 2016-03-31
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Project Status |
Completed (Fiscal Year 2015)
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Budget Amount *help |
¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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Keywords | 上丘 / マウス / 2光子顕微鏡 / in vivo イメージング / 側方抑制 / 視覚 / サッカード / 眼球運動 / in vivo カルシウムイメージング / サッケード / カルシウムイメージング / in vivo |
Outline of Final Research Achievements |
The superior colliculus (SC) is a brainstem center which plays essential roles in mediating the signal for sensory-motor translation. It has been hypothesized that horizontal excitatory and inhibitory interaction in the sSC is important for target selection, however; the way of neuronal implementation remained elusive, especially at the neuronal population level. In this study we applied in vivo two-photon Ca2+ imaging and simultaneously recored neuronal population activities evoked by visual stimuli. I examined excitatory and inhibitory interaction by presenting spatially separated visual stimuli and stimulus with different sizes. I found that Mexican hat-like lateral interaction is implemented as a neuronal population activity. I also recorded eye movements from head-fixed awake mice. To induce saccade-like eye movement frequently, I tested several kinds of visual stimuli which contains motional information.
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Report
(3 results)
Research Products
(12 results)
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[Journal Article] in vivo two-photon imaging of dendritic spines in marmoset neocortex.2015
Author(s)
Osamu Sadakane, Akiya Watakabe, Masanari Ohtsuka, Masafumi Takaji, Tetsuya Sasaki, Masatoshi Kasai, Tadashi Isa, Go Kato, Junichi Nabekura, Hiroaki Mizukami, Keiya Ozawa, Hiroshi Kawasaki, and Tetsuo Yamamori
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Journal Title
eNeuro
Volume: 2(4)
Issue: 4
Pages: 1-10
DOI
Related Report
Peer Reviewed / Open Access / Acknowledgement Compliant
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