| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2016: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
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| Outline of Final Research Achievements |
We examined about gene expression pattern on palate development to identify the susceptibility genes of cleft palate, Palate tissues during development period were taken out and genetic manifestation was analyzed using a DNA microarray. Many genes participated in the palate formation, and moreover the genetic manifested pattern was different in hard palate and soft palate. It was considered to develop the symptoms by different mechanisms in each pattern of cleft.
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