Elucidation of the palatal elevation system via MAPK pathway
| Project/Area Number |
26861731
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Surgical dentistry
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| Research Institution | Kyushu University |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2016: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
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| Keywords | 口唇口蓋裂 / 疾患感受性遺伝子 / MAPK / 口蓋突起挙上 / 遺伝子発現解析 / 口蓋裂 / 口蓋発生 |
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| Outline of Final Research Achievements |
We examined about gene expression pattern on palate development to identify the susceptibility genes of cleft palate, Palate tissues during development period were taken out and genetic manifestation was analyzed using a DNA microarray. Many genes participated in the palate formation, and moreover the genetic manifested pattern was different in hard palate and soft palate. It was considered to develop the symptoms by different mechanisms in each pattern of cleft.
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Report
(4 results)
Research Products
(7 results)
