Effect of prenyl flavonoids on recovery from disuse muscle atrophy
| Project/Area Number |
26892020
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| Research Category |
Grant-in-Aid for Research Activity Start-up
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| Allocation Type | Single-year Grants |
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| Research Field |
Food science
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| Research Institution | The University of Tokushima |
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Principal Investigator |
MUKAI Rie 徳島大学, 大学院医歯薬学研究部, 助教 (90547978)
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| Project Period (FY) |
2014-08-29 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Keywords | フラボノイド / 筋萎縮 / 筋合成 / プレニルフラボノイド / 骨格筋 / ポリフェノール / タンパク質分解 / エストロゲン / ナリンゲニン |
|---|
| Outline of Final Research Achievements |
We hypothesized that prenyl flavonoid improves the recovery of skeletal muscle from the disuse muscle atrophy. Right ankle of hind leg of mouse was fixed to induce disuse muscle atrophy. After that, prenyl flavonoid mixed diet or control diet was supplied to mice. To estimate the atrophy, weight of muscle was measured and ratio of atrophied muscle to control muscle was calculated. Muscle weight in supplementation group showed higher recovery than that in control diet group.
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Report
(3 results)
Research Products
(6 results)
