The role of THBS-1 expression in radioresistance
| Project/Area Number |
26893177
|
|---|
| Research Category |
Grant-in-Aid for Research Activity Start-up
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
General surgery
|
|---|
| Research Institution | The University of Tokushima |
|---|
Principal Investigator |
TAKASU Chie 徳島大学, 大学病院, 助教 (70582823)
|
|---|
| Project Period (FY) |
2014-08-29 – 2016-03-31
|
| Project Status |
Completed (Fiscal Year 2015)
|
| Budget Amount *help |
¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
|
|---|
| Keywords | HDAC阻害剤 / 放射線増感作用 / ヒストン脱アセチル化酵素阻害剤 / 血管新生 |
|---|
| Outline of Final Research Achievements |
We revealed that VEGF (Vascular endothelial growth factor), Beclin3 (autophagy-related gene) and caspase 3 (autophagy-related gene) played important role for enhancing
radiosensitivity by HDAC inhibitor.
|
Report
(3 results)
Research Products
(4 results)
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[Journal Article] The Relationship of CD133, Histone Deacetylase 1 and Thrombospondin-1 in Gastric Cancer.2015
Author(s)
Eto S, Yoshikawa ｋ, Shimada M, Higashijima J, Tokunaga T, Nakao T, Nishi M, Takasu C, Sato H, Kurita N.
-
Journal Title
Anticancer Res
Volume: 35(4)
Pages: 2071-2076
Related Report
Peer Reviewed
-
[Journal Article] The Relationship of CD133, Histone Deacetylase 1 and Thrombospondin-1 in Gastric Cancer.2015
Author(s)
Eto S1, Yoshikawa K2, Shimada M1, Higashijima J1, Tokunaga T1, Nakao T1, Nishi M1, Takasu C1, Sato H1, Kurita N1.
-
Journal Title
Anticancer Res
Volume: 35
Pages: 2071-2076
Related Report
Peer Reviewed
-
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