レゾナンスバイオ国際活動支援

• 研究領域: 共鳴誘導で革新するバイオイメージング
• 研究課題/領域番号: 15K21746
• 研究種目: 新学術領域研究(研究領域提案型)
• 配分区分: 基金
• 審査区分: 生物系
• 研究機関: 国立研究開発法人理化学研究所
• 研究代表者: 宮脇 敦史 国立研究開発法人理化学研究所, 脳神経科学研究センター, チームリーダー (80251445)
• 研究分担者: 今村 健志 愛媛大学, 医学系研究科, 教授 (70264421) ; 松田 道行 京都大学, 生命科学研究科, 教授 (10199812)
• 研究期間 (年度): 2015-11-06 – 2021-03-31
• 研究課題ステータス: 完了 (2020年度)
• 配分額: 63,700千円 (直接経費: 49,000千円、間接経費: 14,700千円); 2019年度: 13,650千円 (直接経費: 10,500千円、間接経費: 3,150千円); 2018年度: 13,650千円 (直接経費: 10,500千円、間接経費: 3,150千円); 2017年度: 13,650千円 (直接経費: 10,500千円、間接経費: 3,150千円); 2016年度: 13,650千円 (直接経費: 10,500千円、間接経費: 3,150千円); 2015年度: 9,100千円 (直接経費: 7,000千円、間接経費: 2,100千円)
• キーワード: バイオイメージング / 画像処理 / ワークショップ / シンポジウム / 顕微鏡技術 / FRET / ケミカルバイオロジー / 画像解析

研究成果の概要

本プロジェクトは以下の５つの柱で構成される。１）国際シンポジウム、学会との共催、２）若手育成・国際連携推進、３）技術講習会、４）Webによる情報発信、５）Forum開催。プロジェクト内の若手研究者には、海外研究者と一緒に、国際シンポジウムを企画・運営させた。また、本領域の成果の国際的発信を狙い、国際会議開催の定期化やウェブサイトの英文化を徹底した。さらに、本プロジェクトの集大成として、国際シンポジウムを開催し、最先端の海外研究者と、バイオイメージング技術開発研究の将来を議論する機会を得ることができた。

研究成果の学術的意義や社会的意義

本プロジェクトにおいては、革新的なバイオイメージング技術を、国際シンポジウム、若手ワークショップ、イメージング講習会、ホームページなどを通じて国内外に広く発信してきた。有難いことに、学術分野のみならず産業界からも多くの賛同が得られ、集大成となった国際シンポジウムでは多数の企業参加もあり、新たな産学連携の芽を作った。近未来的に、国民生活を支える技術の革新に我々レゾナンスバイオが貢献することが期待される。

研究成果

• [国際共同研究] The Scripps Research Institute(米国)
• [国際共同研究] The Chinese University of Hong Kong/National Tsing Hua University(その他の国・地域)
• [国際共同研究] EMBO(ドイツ)
• [国際共同研究] 中央研究院(その他の国・地域)
• [国際共同研究] Salk Institute(米国)
• [国際共同研究] Academia Sinica(台湾)
• [国際共同研究] Stanford大学(米国)
• [学会発表] The real thrill of bioimaging after a phantom FRET (2021)
  • 著者名/発表者名: Atsushi Miyawaki
  • 学会等名: Cell Signaling Distinguished Lecture
  • 招待講演
• [学会発表] Whole-organ imaging for cochlear duct morphogenesis -Differential growth hypothesis for bending force generation (2019)
  • 著者名/発表者名: Mamoru Ishii
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Establishment of live imaging system for the analysis of bone growth effect of C-type natriuretic peptide using FRET biosensor mice (2019)
  • 著者名/発表者名: Keisho Hirota
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] SLIPT and photoSLIPT: chemical and optochemical tools for controlling protein localization in living cells (2019)
  • 著者名/発表者名: Shinya Tsukiji
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Chemogenetic control of protein activity in living cells using synthetic protein-assembled clusters (2019)
  • 著者名/発表者名: Masaru Yoshikawa
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Cancer cell-derived prostanoids shape the pro-tumor microenvironment, enhancing calcium signaling in cancer cells (2019)
  • 著者名/発表者名: Yoshinobu Konishi
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] FRET-assisted photoactivation of flavoproteins for in vivo two-photon optogenetics (2019)
  • 著者名/発表者名: Tomoaki Kinjo
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Enhanced fluorescence of near-infrared fluorescent proteins by the deficiency of biliverdin reductase-A gene in vivo (2019)
  • 著者名/発表者名: Kenju Kobachi
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Imaging neuronal network controlling circadian and ultradian calcium rhythms in mammals (2019)
  • 著者名/発表者名: Ryosuke Enoki
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] In vivo two-photon deep and wide-field imaging utilizing novel fluoropolymer PEO-CYTOP nanosheet (2019)
  • 著者名/発表者名: Taiga Takahashi
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Two-photon excitation spinning-disk confocal microscopy for higher-dimensional bioimaging (2019)
  • 著者名/発表者名: Kohei Otomo
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Super-resolution Imaging by Vector Beams (2019)
  • 著者名/発表者名: Shun-ichi Sato
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] In vivo visualization of dendritic spines in deep regions of the mouse prefrontal cortex with two-photon excitation adaptive optical microscopy (2019)
  • 著者名/発表者名: Kazushi Yamaguchi
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Two-photon pulsed STED nanoscopy utilizing electrically controllable components (2019)
  • 著者名/発表者名: Hirokazu Ishii
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Near-Infrared Light Triggered Cancer Theranostics Based on Rear-Earth Doped Ceramics Nanoparticles (2019)
  • 著者名/発表者名: Masao Kamimura
  • 学会等名: Resonance Bio International Symposium
  • 国際学会 / 招待講演
• [学会発表] Detection of protein-conformation switch by second harmonic generation microscopy (2019)
  • 著者名/発表者名: Taro Ichimura
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Quantitative Visualization of Lipid Distribution in Mice Liver by Using Near-Infrared Hyperspectral Imaging (2019)
  • 著者名/発表者名: Yuichi Kitagawa
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Near-Infrared Fluorescence Lifetime-Based Contactless Temperature Imaging for Deep Biological Tissues by Using Rare-Earth-Doped Ceramics Particles (2019)
  • 著者名/発表者名: Keiji Miyata
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Synthesis of Bright NIR-II Fluorescent Polymer Nanoparticle with IR-1061 Dye via Mild Heating-Cooling Process for Deep Bioimaging in the Second Biological Window (2019)
  • 著者名/発表者名: Hisanori Kobayashi
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Over-1000nm Near-Infrared Fluorescence Properties of IR-1061 Dye-Loaded Micelles Dispersed in Different Concentration of Hydrogen Ion (2019)
  • 著者名/発表者名: Kazuno Ikeda
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Conjugation of Gd-DOTA to IR1061-PEG based micelles for dual MRI/OTN-NIR imaging (2019)
  • 著者名/発表者名: Doan Thi Kim Dung
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Optical and magnetic multimodal bioimaging probes based on rare-earth doped ceramic nanophosphors (2019)
  • 著者名/発表者名: Karina Nigoghossian
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Phosphate-Based Rapid Optical Clearing for Three-Dimensional Fluorescence Imaging of Mouse Brains (2019)
  • 著者名/発表者名: Masakazu Umezawa
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Computed Tomography for In Vivo Deep Over-Thousand-Nanometer Near-Infrared (OTN-NIR) Fluorescence Imaging (2019)
  • 著者名/発表者名: Masakazu Umezawa
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Stabilization of Indocyanine Green by Energy Transfer in Block Copolymer Micelles (2019)
  • 著者名/発表者名: Gil Yeroslavsky
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Development of new photoactivatable fluorophores for in vivo/ex vivo cell labeling (2019)
  • 著者名/発表者名: Hiroki Kashima
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Rational design of fluorescence probes based on quantum chemical prediction of intramolecular spirocyclization (2019)
  • 著者名/発表者名: Sascha Keller
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Development of Fluorescent Probes for Glycosidase Activities and Application to Cancer and Benign Specific Fluorescence Imaging (2019)
  • 著者名/発表者名: Kyohhei Fujita
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Trimmed Median PCA (2019)
  • 著者名/発表者名: Shin Yoshizawa
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Electric-field control of fluorescence protein emissions at the metal-solution interface (2019)
  • 著者名/発表者名: Hidekazu Tsutsui
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Cloud-based image processing system: RBICP (2019)
  • 著者名/発表者名: Masahiko Morita
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Structural analysis of nucleic acids by controlling the fluorescence blinking (2019)
  • 著者名/発表者名: Kiyohiko Kawai
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Deep learning for cell segmentation with less annotation (2019)
  • 著者名/発表者名: Kazuya Nishimura
  • 学会等名: Resonance Bio International Symposium
  • 国際学会 / 招待講演
• [学会発表] Cell Tracking by estimating cell motions for high-throughput screening (2019)
  • 著者名/発表者名: Junya Hayashida
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Genetically encoded reporter for bimodal optical and PET imaging in the mammalian brain (2019)
  • 著者名/発表者名: Masafumi Shimojo
  • 学会等名: Resonance Bio International Symposium
  • 国際学会 / 招待講演
• [学会発表] Nanoscale dynamics and localization of single endogenous mRNAs in stress granules (2019)
  • 著者名/発表者名: Takashi Funatsu
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Visual Interpretation of U-Net in Bio-medical Images Classification (2019)
  • 著者名/発表者名: Novanto Yudistira
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Feedback Attention Mechanism For Convolutional Neural Network (2019)
  • 著者名/発表者名: Yuki Hiramatsu
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Automatic Image Preprocessing Method Using Deep Learning (2019)
  • 著者名/発表者名: Sota Kato
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Visualization of Pixel-wise Difficulty of Segmentation by CNN (2019)
  • 著者名/発表者名: Daisuke Matsuzuki
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Cytoskeleton-anchoring probes for nanoimaging of oxidative stress (2019)
  • 著者名/発表者名: Tasuku Hirayama
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Optogenetic control of cell-cell communication in the Notch signaling pathway (2019)
  • 著者名/発表者名: Akihiro Isomura
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Multi-photon patterned illumination using a digital micromirror device (2019)
  • 著者名/発表者名: Keisuke Isobe
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Nanosheet Wrapping Technology ~Coverslip-free imaging for looking deeper into a tissue at high resolution~ (2019)
  • 著者名/発表者名: Yosuke Okamura
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Porous nanosheet wrapping: a novel immobilization method for long-term imaging of zebrafish development without anesthesia (2019)
  • 著者名/発表者名: Hong Zhang
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Nanostructure and molecular dynamics of dendritic spines (2019)
  • 著者名/発表者名: Shigeo Okabe
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Highly sensitive, multiplex bioluminescence imaging of cancer metastasis in deep tissues (2019)
  • 著者名/発表者名: Takahiro Kuchimaru
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Development of multi-cell-type segmentation algorithm by unsupervised feature learning (2019)
  • 著者名/発表者名: Yuya Kobayashi
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Development of the pH-responsive photoacoustic imaging agent (2019)
  • 著者名/発表者名: Koki Tsuchiya
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Beyond multicolor superresolution microscopy: Accurate 3D registration and distance measurement (2019)
  • 著者名/発表者名: Atsushi Matsuda
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Optical Control of Cell Signaling by Genetically Encoded PhyB-PIF System (2019)
  • 著者名/発表者名: Kazuhiro Aokii
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Quantification of GPCR Signaling by Multiplexed Fluorescence Imaging (2019)
  • 著者名/発表者名: Ryosuke Tany
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Development and application of a new optogenetic system to manipulate intracellular contractile force (2019)
  • 著者名/発表者名: Kei Yamamoto
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Allele-Selective Genome Editing by Fine-Tuning CRISPR-Cas9 Activity (2019)
  • 著者名/発表者名: Masaki Kawamata
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Optical induction of signaling and plasticity of single dendritic spines by photoactivatable CaMKII (2019)
  • 著者名/発表者名: Akihiro Shibata
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Analysis of acetylcholine-induced tissue-widely synchronized Ca2+ oscillations in rat submandibular gland using intravital imaging (2019)
  • 著者名/発表者名: Akihiro Nezu
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Multimodal multiphoton imaging of plasma membrane by dye-based second-harmonic and sum-frequency generation (2019)
  • 著者名/発表者名: Takaha Mizuguchi
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Multi-scale imaging from the whole brain level to the ultrastructure level by using a modified ScaleS method (2019)
  • 著者名/発表者名: Hiroyuki Hioki
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Real time recording of clock gene expression in multiple tissues of freely moving mice (2019)
  • 著者名/発表者名: Toshiyuki Hamada
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Bio-image informatics for whole brain imaging and analysis of neural activity of C. elegans (2019)
  • 著者名/発表者名: Yu Toyoshima
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Development of Chemical Tools with Fluorescence Switch for Biomolecular Imaging (2019)
  • 著者名/発表者名: Yuichiro Hori
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Single particle motions of axonal proteins captured by a confocal laser scanning microscopy (2019)
  • 著者名/発表者名: Kazunari Mouri
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] A cell cycle-dependent CRISPR-Cas9 activation system for increased accuracy of genome editing (2019)
  • 著者名/発表者名: Wataru Nomura
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Development of a pH-adjustable tissue clearing solution for biological multicolor deep imaging (2019)
  • 著者名/発表者名: Kazuya Okami
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Multi-modal optical coherence microscopy at longer wave-length range using wavelength tunable ultrashort pulse fi-ber laser for deep imaging (2019)
  • 著者名/発表者名: Norihiko Nishizawa
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] An End-to-end CNN and CLSTM Network with 3D Anchors for Mitotic Cell Detection in 4D Microscopic Images (2019)
  • 著者名/発表者名: Jianqing Liu
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Development of activatable fluorescence probes for detecting basic carboxypeptidase activity (2019)
  • 著者名/発表者名: Hirohisa Iwaki
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] mage Denoiser for Microscopic Images Based on Noising and Denoising Approach (2019)
  • 著者名/発表者名: Akinori Hidaka
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] A new optical method for identifying a time window of syn-aptic plasticity in hippocampus (2019)
  • 著者名/発表者名: Akihiro Goto
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Data mining of microspectroscopic image using intrinsic features of overcomplete independent bases (2019)
  • 著者名/発表者名: Yu Nagashima
  • 学会等名: Resonance Bio International Symposium
  • 国際学会
• [学会発表] Foerster resonance energy transfer-assisted photoactivation of CRY2 for the optical control of protein interactions by two-photon excitation microscopy (2019)
  • 著者名/発表者名: Tomoaki Kinjo
  • 学会等名: Joint Meeting for Young Researchers on “Frontiers in Imaging Probes and Technologies”
  • 国際学会
• [学会発表] In vivo two-photon laser ablation of single neural processes within deep regions ofliving mouse brains (2019)
  • 著者名/発表者名: Kazuhisa Yamaguchi
  • 学会等名: Joint Meeting for Young Researchers on “Frontiers in Imaging Probes and Technologies”
  • 国際学会
• [学会発表] Visualization of rapid elimination of hematogenous metastatic tumor cells by NK cells in the lung (2019)
  • 著者名/発表者名: Hiroshi Ichise
  • 学会等名: Joint Meeting for Young Researchers on “Frontiers in Imaging Probes and Technologies”
  • 国際学会
• [学会発表] Quantification of GPCR signaling by live cell imaging (2019)
  • 著者名/発表者名: Ryosuke Tany
  • 学会等名: Joint Meeting for Young Researchers on “Frontiers in Imaging Probes and Technologies”
  • 国際学会
• [学会発表] Two-photon excitation spinning disk microscopy for multi-dimensional bioimaging (2019)
  • 著者名/発表者名: Kohei Otomo
  • 学会等名: Joint Meeting for Young Researchers on “Frontiers in Imaging Probes and Technologies”
  • 国際学会
• [学会発表] Development of nucleus-specific fluorescent dyes and nucleus imaging of mammalian and plant cells (2019)
  • 著者名/発表者名: Akinobu Nakamura
  • 学会等名: Joint Meeting for Young Researchers on “Frontiers in Imaging Probes and Technologies”
  • 国際学会
• [学会発表] Three-Dimensional Imaging of Over-1000-Nanometer (OTN) Near-Infrared Fluorescence by Sheet-Laser Excitation (2019)
  • 著者名/発表者名: Masakazu Umezawa
  • 学会等名: Joint Meeting for Young Researchers on “Frontiers in Imaging Probes and Technologies”
  • 国際学会
• [学会発表] Differential contributions of nonmuscle myosin IIA and IIB to cytokinesis in human immortalized fibroblasts (2019)
  • 著者名/発表者名: Kei Yamamoto
  • 学会等名: Joint Meeting for Young Researchers on “Frontiers in Imaging Probes and Technologies”
  • 国際学会
• [学会発表] Multimodal imaging systems based on rare-earth doped ceramic nanophosphors (2019)
  • 著者名/発表者名: Karina Nigoghossian
  • 学会等名: Joint Meeting for Young Researchers on “Frontiers in Imaging Probes and Technologies”
  • 国際学会
• [学会発表] Morphological analysis of dendritic spine structures in the hippocampal neurons activated during fear memory recall by whole-cell high-resolution imaging using Airyscan FAST microscopy (2019)
  • 著者名/発表者名: Keiichiro Minatohara
  • 学会等名: Joint Meeting for Young Researchers on “Frontiers in Imaging Probes and Technologies”
  • 国際学会
• [学会発表] Visualization of directional-transport mechanisms in living fertilized eggs (2019)
  • 著者名/発表者名: Hirokazu Ishii
  • 学会等名: Joint Meeting for Young Researchers on “Frontiers in Imaging Probes and Technologies”
  • 国際学会
• [学会発表] In vivo imaging in mouse brains in wide and deep regions utilizing novel nanosheets “PEO-CYTOP” (2019)
  • 著者名/発表者名: Taiga Takahashi
  • 学会等名: Joint Meeting for Young Researchers on “Frontiers in Imaging Probes and Technologies”
  • 国際学会
• [学会発表] FRET Imaging Analysis of RB phosphorylation and Cell Cycle Progression (2019)
  • 著者名/発表者名: Masaya MUKAI
  • 学会等名: Joint Meeting for Young Researchers on “Frontiers in Imaging Probes and Technologies”
  • 国際学会
• [学会発表] Photoprotection of Indocyanine Green by Energy Transfer in Various Micellar Systems (2019)
  • 著者名/発表者名: Gil Yeroslavsky
  • 学会等名: Joint Meeting for Young Researchers on “Frontiers in Imaging Probes and Technologies”
  • 国際学会
• [学会発表] Visualizing Neuronal Circuits Controlling Circadian and Ultradian Rhythms in Mammals (2019)
  • 著者名/発表者名: Ryosuke Enoki
  • 学会等名: Joint Meeting for Young Researchers on “Frontiers in Imaging Probes and Technologies”
  • 国際学会
• [学会発表] Illuminating Neuronal Circuits Controlling Circadian and Ultradian Rhythms in Mammals (2018)
  • 著者名/発表者名: Ryosuke Enoki
  • 学会等名: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • 国際学会
• [学会発表] Fabrication of Fluoropolymer Nanosheets as a Wrapping Mount for High Quality Tissue Imaging (2018)
  • 著者名/発表者名: Yosuke Okamura
  • 学会等名: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • 国際学会
• [学会発表] Development of multi-point scanning two-photon microscopy utilizing polarizing optics and its application for intravital imaging (2018)
  • 著者名/発表者名: Ai Goto
  • 学会等名: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • 国際学会
• [学会発表] Manipulation of fission yeast cell cycle by red/infrared Lightinduced Dimerization of PhyB-PIF (2018)
  • 著者名/発表者名: Yuhei Goto
  • 学会等名: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • 国際学会
• [学会発表] Cytoskeletal dynamics for directional transport in the fertilized ascidian eggs (2018)
  • 著者名/発表者名: Hirokazu Ishii
  • 学会等名: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • 国際学会
• [学会発表] Polymer Conjugated Nanophosphors for Over-1000 nm Near- Infrared Fluorescence Imaging (2018)
  • 著者名/発表者名: Masao Kamimura
  • 学会等名: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • 国際学会
• [学会発表] A multi-bioluminescence reporter system visualizes tumorstromal interactions during therapeutic treatment of bone metastasis (2018)
  • 著者名/発表者名: Takahiro Kuchimaru
  • 学会等名: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • 国際学会
• [学会発表] Two-photon excitation spinning disk confocal microscopy utilizing two laser light sources (2018)
  • 著者名/発表者名: Takafumi Kamada
  • 学会等名: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • 国際学会
• [学会発表] Structured illumination microscopy-based computational analysis of spine head geometry and its application to live cell imaging (2018)
  • 著者名/発表者名: Yutaro Kashiwagi
  • 学会等名: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • 国際学会
• [学会発表] Highly-sensitive in vivo tracking of cancer cells using nearinfrared bioluminescence technologies (2018)
  • 著者名/発表者名: Misa Minegishi
  • 学会等名: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • 国際学会
• [学会発表] Application of a highly photostable near-infrared labeling agent in muse brain imaging in vivo (2018)
  • 著者名/発表者名: Ryosuke Kawakami
  • 学会等名: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • 国際学会
• [学会発表] Development of fluorescent probes with m6A-binding protein for detection of RNA methylation (2018)
  • 著者名/発表者名: Keisuke Nomura
  • 学会等名: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • 国際学会
• [学会発表] Development of spontaneously blinking fluorophores based on nucleophilic addition of intracellular glutathione for superresolution imaging (2018)
  • 著者名/発表者名: Akihico Morozumi
  • 学会等名: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • 国際学会
• [学会発表] Sub-100 nm scale nanoarray for single-exosome analysis (2018)
  • 著者名/発表者名: Kyohei Okubo
  • 学会等名: International Meeting on Bioimaging for Young Researchers "Chanpuru"
• [学会発表] Theranostic nanosystems based on luminescence of rare-earth doped ceramic nanophosphors (2018)
  • 著者名/発表者名: Karina Nigoghossian
  • 学会等名: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • 国際学会
• [学会発表] Spectral-morphological classification of liver fibrosis using multi-photon excitation microscopy and marker-based segmentation (2018)
  • 著者名/発表者名: Takashi Saitou
  • 学会等名: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • 国際学会
• [学会発表] Improvements of two-photon excitation microscopy for clear visualization of intravital subcellular structures (2018)
  • 著者名/発表者名: Kohei Otomo
  • 学会等名: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • 国際学会
• [学会発表] In vivo manipulation of signal transduction using red/infrared light in C. elegans (2018)
  • 著者名/発表者名: Shigekazu Oda
  • 学会等名: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • 国際学会
• [学会発表] Single-cell kinase activity measurements from the mouse retina by two-photon ex vivo live imaging. (2018)
  • 著者名/発表者名: Shinya Sato
  • 学会等名: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • 国際学会
• [学会発表] Non-empirical Design of Spontaneously Blinking Fluorophores for Super-resolution Imaging (2018)
  • 著者名/発表者名: Ryo Tachibana
  • 学会等名: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • 国際学会
• [学会発表] Genetically encoded reporter for bimodal optical and PET imaging in the mammalian brain. (2018)
  • 著者名/発表者名: Masafumi Shimojo
  • 学会等名: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • 国際学会
• [学会発表] Development of 2 photon wide-field light sheet microscopy for Medaka (2018)
  • 著者名/発表者名: Sota Takanezawa
  • 学会等名: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • 国際学会
• [学会発表] Temporal Profile of Notch Signaling Activation during Vertebrate Somitogenesis (2018)
  • 著者名/発表者名: Akari Takagi
  • 学会等名: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • 国際学会
• [学会発表] Real-Time Imaging of Bile Excretion of Nanoparticle Using In Vivo Deep Imaging System with Near-Infrared Fluorescent Probes (2018)
  • 著者名/発表者名: Masakazu Umezawa
  • 学会等名: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • 国際学会
• [学会発表] Application of novel CYTOP nanosheet for in vivo imaging of living mouse brain (2018)
  • 著者名/発表者名: Taiga Takahashi
  • 学会等名: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • 国際学会
• [学会発表] Using nanosheet instead of coverslip for facilitating deep tissue imaging (2018)
  • 著者名/発表者名: Hong Zhang
  • 学会等名: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • 国際学会
• [学会発表] 3D Beef Marbling Extraction (2018)
  • 著者名/発表者名: Shin Yoshizawa
  • 学会等名: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • 国際学会
• [学会発表] In vivo two-photon laser ablation within deep regions of living mouse brains (2018)
  • 著者名/発表者名: Kazushi Yamaguchi
  • 学会等名: International Meeting on Bioimaging for Young Researchers "Chanpuru"
  • 国際学会
• [学会発表] Visualization of transcriptional activities in living fish (2017)
  • 著者名/発表者名: Kenta Terai
  • 学会等名: The 1st ABiS Symposium Towards the Future of Advanced Bioimaging for Life Sciences
  • 発表場所: 自然科学研究機構 岡崎コンファレンスセンター（愛知県岡崎市）
  • 年月日: 2017-02-19
  • 国際学会
• [学会発表] Development of a new murine model of bone metastasis using bioluminescence imaging (2017)
  • 著者名/発表者名: Takahiro Kuchimaru, Shinae Kizaka-Kondoh
  • 学会等名: Taiwan- Japan Joint Meeting on Bioimaging for Young Researchers
  • 国際学会
• [学会発表] Bio-image Informatics for Whole-brain Activity Imaging (2017)
  • 著者名/発表者名: Yu Toyoshima
  • 学会等名: Taiwan- Japan Joint Meeting on Bioimaging for Young Researchers
  • 国際学会
• [学会発表] Detection of LacZ-Positive Cells in Living Tissue with Single-Cell Resolution (2017)
  • 著者名/発表者名: Mako Kamiya, Yasuteru Urano
  • 学会等名: Taiwan- Japan Joint Meeting on Bioimaging for Young Researchers
  • 国際学会
• [学会発表] Development of spontaneously blinking fluorophores based on nucleophilic addition of intracellular glutathione for super-resolution imaging (2017)
  • 著者名/発表者名: Akihico Morozumi, Mako Kamiya, Shinnosuke Uno, Keitaro Umezawa, Toshitada Yoshihara, Seiji Tobita, Yasuteru Urano
  • 学会等名: Taiwan- Japan Joint Meeting on Bioimaging for Young Researchers
  • 国際学会
• [学会発表] A novel method of analyzing molecular activities at single cell level (2017)
  • 著者名/発表者名: Ayako Imanishi, Masaya Sato, Kenta Sumiyama, Kazuhiro Hotta, Michiyuki Matsuda, and Kenta Terai
  • 学会等名: Taiwan- Japan Joint Meeting on Bioimaging for Young Researchers
  • 国際学会
• [学会発表] Visual Mapping of Strain in Elastic Silicone Polymers Based on Energy Transfer Phenomena (2017)
  • 著者名/発表者名: Gil Yeroslavsky, Masao Kamimura, Kohei Soga
  • 学会等名: Taiwan- Japan Joint Meeting on Bioimaging for Young Researchers
  • 国際学会
• [学会発表] Treadmilling of microtubules drives the directional transport of maternal factors in fertilized ascidian eggs (2017)
  • 著者名/発表者名: Hirokazu Ishii, Tomomi Tani
  • 学会等名: Taiwan- Japan Joint Meeting on Bioimaging for Young Researchers
  • 国際学会
• [学会発表] A Fluorescent Probe for Quick Live-Cell Protein Labeling (2017)
  • 著者名/発表者名: Jingchi Gao
  • 学会等名: Taiwan- Japan Joint Meeting on Bioimaging for Young Researchers
  • 国際学会
• [学会発表] Two-photon imaging within living mouse brains improved by easy modifications in the laser irradiation condition (2017)
  • 著者名/発表者名: Kazushi Yamaguchi, Ryoji Kitamura, Ryosuke Kawakami, Tomomi Nemoto
  • 学会等名: Taiwan- Japan Joint Meeting on Bioimaging for Young Researchers
  • 国際学会
• [学会発表] Multi-point scanning two-photon microscopy by utilizing high-peak-power lasers (2017)
  • 著者名/発表者名: Kohei OTOMO, Tomomi NEMOTO
  • 学会等名: Taiwan- Japan Joint Meeting on Bioimaging for Young Researchers
  • 国際学会
• [学会発表] Imaging and manipulation of temperature in single living cells (2017)
  • 著者名/発表者名: Kohki Okabe
  • 学会等名: Taiwan- Japan Joint Meeting on Bioimaging for Young Researchers
  • 国際学会
• [学会発表] Challenge to 3-Dimensional Imaging of Brain Vasculature by Near-Infrared Fluorescence Probe with Light-Sheet Excitation System (2017)
  • 著者名/発表者名: Masakazu Umezawa, Moe Yoshida, Toshihiro Sera, Hideo Yokota
  • 学会等名: Taiwan- Japan Joint Meeting on Bioimaging for Young Researchers
  • 国際学会
• [学会発表] Over-1000 nm Near-Infrared (OTN-NIR) Fluorescence in vivo Imaging (2017)
  • 著者名/発表者名: Masao Kamimura
  • 学会等名: Taiwan- Japan Joint Meeting on Bioimaging for Young Researchers
  • 国際学会
• [学会発表] A multi-bioluminescence reporter system visualizes crosstalk between cancer cells and bone marrow microenvironment (2017)
  • 著者名/発表者名: Misa Minegishi, Tatsuhiro Isozaki, Satoshi Fujimori, Takahiro Kuchimaru
  • 学会等名: Taiwan- Japan Joint Meeting on Bioimaging for Young Researchers
  • 国際学会
• [学会発表] Development of fluorescent/luminescent protein-based biosensors for visualizing kinase activity in living cells (2017)
  • 著者名/発表者名: Naoki Komatsu, Michiyuki Matsuda
  • 学会等名: Taiwan- Japan Joint Meeting on Bioimaging for Young Researchers
  • 国際学会
• [学会発表] Analysis for the activity and phosphorylation states of synaptic proteins (2017)
  • 著者名/発表者名: Tomohisa Hosokawa
  • 学会等名: Taiwan- Japan Joint Meeting on Bioimaging for Young Researchers
  • 国際学会
• [学会発表] Object Segmentation by Integrating Multiple Deep Networks (2017)
  • 著者名/発表者名: Yuki Hiramatsu and Kazuhiro Hotta
  • 学会等名: Taiwan- Japan Joint Meeting on Bioimaging for Young Researchers
  • 国際学会
• [学会発表] Detection of LacZ-Positive Cells in Living Tissue with Single-Cell Resolution (2017)
  • 著者名/発表者名: Mako Kamiya
  • 学会等名: The 1st ABiS Symposium Towards the Future of Advanced Bioimaging for Life Sciences
  • 発表場所: 自然科学研究機構 岡崎コンファレンスセンター（愛知県岡崎市）
  • 国際学会
• [学会発表] Metabolite Gradients (2016)
  • 著者名/発表者名: 下薗哲,宮脇敦史
  • 学会等名: Conference on Resonace Biology for Innovation Bioimaging
  • 発表場所: KKRホテル熱海(静岡県熱海市）
  • 年月日: 2016-03-17
• [学会発表] Spontaneously blinking fluorophores for super-resolution imaging (2016)
  • 著者名/発表者名: 神谷真子
  • 学会等名: Conference on Resonace Biology for Innovation Bioimaging
  • 発表場所: KKRホテル熱海(静岡県熱海市）
  • 年月日: 2016-03-17
• [学会発表] Two-photon excitation spinning disk confocal microscopy by utilizing a high-speak-power 1042-nm laser (2016)
  • 著者名/発表者名: 大友康平、日比輝正、山中祐美、山中博史、根本知己
  • 学会等名: Conference on Resonace Biology for Innovation Bioimaging
  • 発表場所: KKRホテル熱海(静岡県熱海市）
  • 年月日: 2016-03-17
• [学会発表] レゾナンスバイオのためのクラウド型情報処理システム (2016)
  • 著者名/発表者名: 森田雅彦、西村将臣、辻村有紀、井尻敬、吉澤信、横田秀夫
  • 学会等名: Conference on Resonace Biology for Innovation Bioimaging
  • 発表場所: KKRホテル熱海(静岡県熱海市）
  • 年月日: 2016-03-17
• [学会発表] がん転移研究のためのがんモデルメダカの開発とイメージング応用 (2016)
  • 著者名/発表者名: 出口友則、成瀬清、今村健志
  • 学会等名: Conference on Resonace Biology for Innovation Bioimaging
  • 発表場所: KKRホテル熱海(静岡県熱海市）
  • 年月日: 2016-03-16
• [学会発表] Rare-earth Doped Cramic NAnophosphors for Over-1000nm Near-infrared Luminescence Nanothermometry (2016)
  • 著者名/発表者名: Kamimura Masao, Kohei Soga
  • 学会等名: Conference on Resonace Biology for Innovation Bioimaging
  • 発表場所: KKRホテル熱海(静岡県熱海市）
  • 年月日: 2016-03-16
• [学会発表] CT Imaging with X-ray, Neutron, and Near Infrared Rays (2016)
  • 著者名/発表者名: Yoshihiro Sera, Hideo Yokota
  • 学会等名: Conference on Resonace Biology for Innovation Bioimaging
  • 発表場所: KKRホテル熱海(静岡県熱海市）
  • 年月日: 2016-03-16
• [備考] 共鳴誘導で革新するバイオイメージング
  • URL: https://reso.m.ehime-u.ac.jp/concept/
• [備考] 共鳴誘導で革新するバイオイメージング
  • URL: https://reso.m.ehime-u.ac.jp/
• [学会・シンポジウム開催] Resoance Bio International Symposium (2019)
• [学会・シンポジウム開催] Joint Meeting for Young Researchers on “Frontiers in Imaging Probes and Technologies” (2019)
• [学会・シンポジウム開催] International Meeting on Bioimaging for Young Researchers "Chanpuru" (2018)
• [学会・シンポジウム開催] The 1st ABiS Symposium Towards the Future of Advanced Bioimaging for Life Science (2017)
  • 発表場所: 自然科学研究機構岡崎コンファレンスセンター（愛知県岡崎市）
  • 年月日: 2017-02-19
• [学会・シンポジウム開催] Taiwan- Japan Joint Meeting on Bioimaging for Young Researchers (2017)
• [学会・シンポジウム開催] Resonance Bio Workshop 2017 (2017)
  • 発表場所: 自然科学研究機構基礎生物学研究所（愛知県岡崎市）
• [学会・シンポジウム開催] 国際連携企画技術講習会 (2017)
  • 発表場所: 愛媛大学医学部（愛媛県東温市）
• [学会・シンポジウム開催] Forum (Dr.Jan Ellenberg) (2017)
  • 発表場所: 理化学研究所（埼玉県和光市）
• [学会・シンポジウム開催] レゾナンスバイオ公開シンポジウム「Swinging on the Chromophore」 (2016)
  • 発表場所: 熱海
  • 年月日: 2016-03-16