大脳辺縁系における情動・記憶・免疫系の相互干渉機構の解明

• 研究課題/領域番号: 12210009
• 研究種目: 特定領域研究
• 配分区分: 補助金
• 審査区分: 生物系
• 研究機関: 富山医科薬科大学
• 研究代表者: 西条 寿夫 (2004) 富山医科薬科大学, 医学系研究科, 教授 (00189284); 小野 武年 (2000-2003) 富山医科薬科大学, 医学部, 教授 (50019577)
• 研究分担者: 白木 公康 富山医科薬科大学, 医学部, 教授 (50135745) ; 村口 篤 富山医科薬科大学, 医学部, 教授 (20174287) ; 倉知 正佳 富山医科薬科大学, 医学部, 教授 (80019603) ; 許 南浩 岡山大学, 大学院医歯薬学総合研究所, 教授 (70173573) ; 大谷 修 富山医科薬科大学, 医学部, 教授 (90127548) ; 西条 寿夫 富山医科薬科大学, 医学部, 教授 (00189284)
• 研究期間 (年度): 2004
• 研究課題ステータス: 完了 (2004年度)
• 配分額: 107,700千円 (直接経費: 107,700千円); 2004年度: 25,200千円 (直接経費: 25,200千円); 2003年度: 26,400千円 (直接経費: 26,400千円); 2002年度: 26,400千円 (直接経費: 26,400千円); 2001年度: 29,700千円 (直接経費: 29,700千円)
• キーワード: 情動 / 記憶 / 認知 / 免疫 / 大脳辺縁系 / ニューロン活動 / サイトカイン / 行動

研究概要

本研究では、扁桃体および海馬体を含む大脳辺縁系を中心とした情動・記憶・免疫システム間の相互干渉機構を、分子・遺伝子から細胞、個体(行動)レベルまでを含む学際的な研究チームにより総合的に解明した。
1.神経生理学的研究:液晶プロジェクターによるVR仮想空間呈示装置を用い、仮想空間移動課題遂行中のサル海馬体ニューロン活動を解析した。その結果、仮想空間内の特定領域で活動が上昇する場所識別ニューロンが記録され、1)3種類の仮想空間移動課題で活動が異なる、2)特定領域でのみ報酬獲得前あるいは獲得後に活動が増加する、3)特定の仮想空間移動課題で特定方向へ移動しているときのみ活動が増加するなどの特徴的な応答が認められた。これらのことから海馬体は、空間情報だけでなく、課題の種類、報酬予告、報酬獲得のような課題関連情報(非空間情報)も符号化していることが示唆された。
2.神経解剖学的研究:統合失調モデルラットを用い、発達過程の脳における神経栄養因子(BDNF)、ドーパミンなどの神経伝達物質の発現、γ-アミノ酪酸系およびグルタミン酸系ニューロン間のシナプス結合様式などを免疫組織化学、電子顕微鏡観察などにより解析した。
3.分子生物学的研究:1)ラットの脳梗塞モデルを用いて、ニューロカンが脳梗塞後の軸索伸長を制御している可能性を明らかにした。2)カイニン酸の腹腔内投与によるマウスの小脳性失調症を用いて、脳内のIL-1とIL-18が神経細胞の機能に拮抗的に作用することを明らかにした。3)脳由来神経栄養因子(BDNF)をより安定して中枢神経系に挿入できる弱毒HSVベクター(betaH)を開発するため、betaHゲノムのterminalとinternal inverted repeat部立近傍の両方にbeta-gal遺伝子が挿入されるように遺伝子組換えのためのプラスミッドを作成した。
4.神経心理学的研究:1)磁気共鳴画像(MRI)により内側側頭葉構造の体積を測定し検討した結果、統合失調症および統合失調型障害のいずれでも、左右の扁桃体と海馬の体積が健常者より有意に減少していた。これらの結果から、扁桃体および海馬の形態学的変化は、統合失調症への脆弱性に関連すると考えられた。2)思春期前後における海馬体積を検討した結果、男性健常者において思春期に海馬体積が有意に増大することが示された。この所見は、統合失調症で認められる海馬体積の減少所見が思春期における発達の障害に関連することを示唆する。

研究成果

• [雑誌論文] Effects of prenatal maternal stress by repeated cold environment on behavioral and emotional development in the rat offspring. (2005)
  • 著者名/発表者名: Tazumi, T., Hori, E., Uwano, T., Umeno, K, Tanabe, K., Tabuchi.E., Ono, T., Nishijo,H.
  • 雑誌名: Behav. Brain Res. 162 ページ: 153-160
  • 説明: 「研究成果報告書概要(和文)」より
• [雑誌論文] Effects of facial expression on shared attention mechanisms. (2005)
  • 著者名/発表者名: Hori, E., Tazumi, T., Tabuchi, E., Umeno, K., Kamachi, M., Ono, T., Nishijo,H.
  • 雑誌名: Physiol. Behav. 84 ページ: 397-405
  • 説明: 「研究成果報告書概要(和文)」より
• [雑誌論文] Effects of cadmium exposure during pregnancy on trace elements in fetal rat liver and kidney. (2005)
  • 著者名/発表者名: Kuriwaki, J., Nishijo, M., Honda, R., Tawara, K., Nakagawa, H., Hori, E., Nishijo,H.
  • 雑誌名: Toxicol. Lett. 156 ページ: 369-376
  • 説明: 「研究成果報告書概要(和文)」より
• [雑誌論文] 天然匂い物質"セドロール"吸入による自律神経反応 (2005)
  • 著者名/発表者名: Samantha Davawansa, 梅野克身, 矢田幸博, 永嶋義直, 小野武年, 西条寿夫
  • 雑誌名: アロマセラピー学会誌 4 ページ: 17-21
  • 説明: 「研究成果報告書概要(和文)」より
• [雑誌論文] 前頭前野と情動発現 (2005)
  • 著者名/発表者名: 小野武年, 西条寿夫
  • 雑誌名: クリニカルニューロサイエンス 23 ページ: 636-639
  • 説明: 「研究成果報告書概要(和文)」より
• [雑誌論文] Differential characteristics of face neuron responses within the anterior superior temporal sulcus of macaques. (2005)
  • 著者名/発表者名: DeSouza, W.C., Eifuku, S., Tamura, R., Nishijo, H., Ono.T.
  • 雑誌名: J. Neurophysiol. 94 ページ: 1252-1266
  • 説明: 「研究成果報告書概要(和文)」より
• [雑誌論文] Place-related neural responses in the monkey hippocampal formation i a virtual space. (2005)
  • 著者名/発表者名: Hori, E., Nishio, Y., Kazui, K., Umeno, K., Tabuchi, E., Sasaki, K., Endo, S., Ono, T., Nishijo, H.
  • 雑誌名: Hippocampus 15 ページ: 991-996
  • 説明: 「研究成果報告書概要(和文)」より
• [雑誌論文] Effects of prenatal maternal stress by repeated cold environment on behavioral and emotional development in the rat offspring. (2005)
  • 著者名/発表者名: Tazumi, T., Hori, E., Uwano, T., Umeno, K, Tanabe, K., Tabuchi, E., Ono, T., Nishijo, H.
  • 雑誌名: Behav Brain Res 162 ページ: 153-160
  • 説明: 「研究成果報告書概要(欧文)」より
• [雑誌論文] Effects of facial expression on shared attention mechanisms. (2005)
  • 著者名/発表者名: Hori, E., Tazumi, T., Tabuchi, E., Umeno, K., Kamachi, M., Ono, T., Nishijo, H.
  • 雑誌名: Physiol Behav 84 ページ: 397-405
  • 説明: 「研究成果報告書概要(欧文)」より
• [雑誌論文] Effects of cadmium exposure during pregnancy on trace elements in fetal rat liver and kidney. (2005)
  • 著者名/発表者名: Kuriwaki, J., Nishijo, M., Honda, R., Tawara, K., Nakagawa, H., Hori, E., Nishijo, H.
  • 雑誌名: Toxicol Lett 156 ページ: 369-76
  • 説明: 「研究成果報告書概要(欧文)」より
• [雑誌論文] Differential characteristics of face neuron responses within the anterior superior temporal sulcus of macaques. (2005)
  • 著者名/発表者名: DeSouza, WC., Eifuku, S., Tamura, R., Nishijo, H., Ono, T.
  • 雑誌名: J neurophysiol 94 ページ: 1252-1266
  • 説明: 「研究成果報告書概要(欧文)」より
• [雑誌論文] Place-Related neural responses in the monkey hippocampal formation in a virtual space. (2005)
  • 著者名/発表者名: Hori, E., Nishio, Y, Kazui, K., Umeno, K., Tabuchi, E., Sasaki, K., Endo, S., Ono, T., Nishijo, H.
  • 雑誌名: Hippocampus 15 ページ: 991-996
  • 説明: 「研究成果報告書概要(欧文)」より
• [雑誌論文] Autonomic responses during inhalation of natural flagrance of "CEDROL" in humans. (2005)
  • 著者名/発表者名: Dayawansa, S., Umeno, K., Yada, Y., Nagashima, Y., Ono, T., Nishijo, H.
  • 雑誌名: Journal of Japanese Society of Aromatherapy 4 ページ: 17-21
  • 説明: 「研究成果報告書概要(欧文)」より
• [雑誌論文] Prefrontal cortex and emotional expression. (2005)
  • 著者名/発表者名: Ono, T., Nishijo, H.
  • 雑誌名: Clinical Neuroscience 23 ページ: 636-639
  • 説明: 「研究成果報告書概要(欧文)」より
• [雑誌論文] 天然匂い物質"セドロール"吸入による自律神経反応 (2005)
  • 著者名/発表者名: Samantha Davawansa, 梅野克身, 矢田幸博, 永嶋義直, 小野武年, 西条寿夫
  • 雑誌名: アロマセラピー学会誌 (印刷中)
• [雑誌論文] 前頭前野と情動発現 (2005)
  • 著者名/発表者名: 小野武年, 西条寿夫
  • 雑誌名: クリニカルニューロサイエンス (印刷中)
• [雑誌論文] Male-specific volume of the human hippocampus during adolescence. (2005)
  • 著者名/発表者名: Suzuki, M., Hgino, H., Nohara, S., Zhou, S., Kawasaki, Y., Takahashi, T., Matsui, M., Seto, H., Ono, T., Kurachi, M.
  • 雑誌名: Cereb Cortex 15 ページ: 187-193
• [雑誌論文] Effects of non-saponin fraction of red ginseng on learning deficits in aged rats. (2004)
  • 著者名/発表者名: Kurimoto, H., Nishijo, H., Uwano, T., Yamaguchi, H., Zhong, Y-M., Kawanishi, K., Ono,T.
  • 雑誌名: Physiol. Behav. 82 ページ: 345-355
  • 説明: 「研究成果報告書概要(和文)」より
• [雑誌論文] Comparison of brain activity between dopamine d2 receptor-knockoutand wild mice in response to dopamine agonist and antagonist assessed by FMRI. (2004)
  • 著者名/発表者名: Kuriwaki, J., Nishijo, H., Kondoh, T., Uwano, T., Torii, K, Katsuki, M., Ono T.
  • 雑誌名: Neurosignals 13 ページ: 227-240
  • 説明: 「研究成果報告書概要(和文)」より
• [雑誌論文] Neuronal correlates of face identification in the monkey anterior temporal cortical areas. (2004)
  • 著者名/発表者名: Eifuku, E., De, Souza, W.C., Tamura, R., Nishijo, H., Ono,T.
  • 雑誌名: J. Neurophysiol. 91 ページ: 358-371
  • 説明: 「研究成果報告書概要(和文)」より
• [雑誌論文] Effects of Choto-san and hooks and stems of Uncaria sinensis on antioxidant enzyme activities in the gerbil brain after transient forebrain ischemia. (2004)
  • 著者名/発表者名: Yokoyama, K., Shimada, Y., Hori, E., Nakagawa, T., Takagi, S., Sekiya, N., Kouta, K., Nishijo, H., Yokozawa, T., Terasawa K.
  • 雑誌名: J. Ethnopharmacol. 95 ページ: 335-343
  • 説明: 「研究成果報告書概要(和文)」より
• [雑誌論文] Protective effects of choto-san and hooks and stems of Uncaria sinensis against delayed neuronal death after transient forebrain ischemia in gerbil. (2004)
  • 著者名/発表者名: Yokoyama, K., Shimada, Y., Hori, E., Sekiya, N., Goto, H., Sakakibara, I., Nishijo, H., Terasawa K.
  • 雑誌名: Phytomedicine 11 ページ: 478-489
  • 説明: 「研究成果報告書概要(和文)」より
• [雑誌論文] Proof of the mysterious efficacy of Ginseng basic and clinical trials effects of red Ginseng : on learning and memory deficits in an animal model of amnesia. (2004)
  • 著者名/発表者名: Nishijo, H., Uwano, T., Zhuong, Y-M., Ono,T.
  • 雑誌名: J. Pharmacol. Sci. 95 ページ: 145-152
  • NAID: 10013294615
  • 説明: 「研究成果報告書概要(和文)」より
• [雑誌論文] 双極子追跡法によるに視覚認知機能に関わる脳内電流発生源の推定 (2004)
  • 著者名/発表者名: 西条寿夫, 柴田 孝, 小野武年
  • 雑誌名: 臨床脳波 46 ページ: 778-784
  • 説明: 「研究成果報告書概要(和文)」より
• [雑誌論文] 大脳機能の新しいパースペクティブ : 社会的認知と情動発現 偏桃体と前頭葉の役割 (2004)
  • 著者名/発表者名: 堀 悦郎, 西条寿夫, 小野武年
  • 雑誌名: 脳と神経 56 ページ: 109-120
  • 説明: 「研究成果報告書概要(和文)」より
• [雑誌論文] 扁桃体における情動学習の神経・分子機構 (2004)
  • 著者名/発表者名: 西条寿夫, 小野武年
  • 雑誌名: Molecular Medicine 41 ページ: 1136-1148
  • 説明: 「研究成果報告書概要(和文)」より
• [雑誌論文] 食物報酬の認知と摂食行動の神経機構 (2004)
  • 著者名/発表者名: 西条寿夫, 田渕英一, 小野武年
  • 雑誌名: 肥満研究 10 ページ: 4-11
  • NAID: 10016998596
  • 説明: 「研究成果報告書概要(和文)」より
• [雑誌論文] 自己の情動反応の表出と他個体の情動反応の認知における扁桃体の役割-動物を対象にした侵襲的脳研究の動向- (2004)
  • 著者名/発表者名: 田積 徹, 西条寿夫, 小野武年
  • 雑誌名: 心理学評論 47 ページ: 8-28
  • NAID: 130007631262
  • 説明: 「研究成果報告書概要(和文)」より
• [雑誌論文] Effects of non-saponin fraction of red ginseng on learning deficits in aged rats. (2004)
  • 著者名/発表者名: Kurimoto, H., Nishijo, H., Uwano, T., Yamaguchi, H., Zhong, Y-M., Kawanishi, K., Ono, T.
  • 雑誌名: Physiol Behav 82 ページ: 345-355
  • 説明: 「研究成果報告書概要(欧文)」より
• [雑誌論文] Comparison of brain activity between dopamine d2 receptor-knockout and wild mice in response to dopamine agonist and antagonist assessed by FMRI. (2004)
  • 著者名/発表者名: Kuriwaki, J., Nishijo, H., Kondoh, T., Uwano, T., Torii, K., Katsuki, M., Ono, T.
  • 雑誌名: Neuro Signals 13 ページ: 227-240
  • 説明: 「研究成果報告書概要(欧文)」より
• [雑誌論文] Neuronal correlates of face identification in the monkey Anterior temporal cortical areas. (2004)
  • 著者名/発表者名: Eifuku, E., De, Souza, W.C., Tamura, R., Nishijo, H., Ono, T.
  • 雑誌名: J Neurophysiol 91
  • 説明: 「研究成果報告書概要(欧文)」より
• [雑誌論文] Effects of Choto-san and hooks and stems of Uncaria sinensis on antioxidant enzyme activities in the gerbil brain after transient forebrain ischemia. (2004)
  • 著者名/発表者名: Yokoyama, K., Shimada, Y., Hori, E., Nakagawa, T., Takagi, S., Sekiya, N., Kouta, K., Nishijo, H., Yokozawa, T., Terasawa, K.
  • 雑誌名: J Ethnopharmacol 95 ページ: 335-343
  • 説明: 「研究成果報告書概要(欧文)」より
• [雑誌論文] Protective effects of choto-san and hooks and stems of Uncaria sinensis against delayed neuronal death after transient forebrain ischemia in gerbil. (2004)
  • 著者名/発表者名: Yokoyama, K., Shimada, Y., Hori, E., Sekiya, N., Goto, H., Sakakibara, I., Nishijo, H,.Terasawa, K.
  • 雑誌名: Phytomedicine 11 ページ: 478-489
  • 説明: 「研究成果報告書概要(欧文)」より
• [雑誌論文] Proof of the mysterious efficacy of Ginseng basic and clinical trials effects of red Ginseng : on learning and memory deficits in an animal model of amnesia. (2004)
  • 著者名/発表者名: Nishijo, H., Uwano, T., Zhuong, Y-M., Ono, T.
  • 雑誌名: J Pharmacol Sci 95 ページ: 145-152
  • NAID: 10013294615
  • 説明: 「研究成果報告書概要(欧文)」より
• [雑誌論文] Localization of current source generators involved in visual recognition by means of the dipole tracing method (2004)
  • 著者名/発表者名: Nishijo, H., Shibata, T, Ono, T.
  • 雑誌名: Rinsyou Nouha 46 ページ: 778-784
  • NAID: 40019991208
  • 説明: 「研究成果報告書概要(欧文)」より
• [雑誌論文] A role of the amygdala and frontal lobe in social cognition and emotion. (2004)
  • 著者名/発表者名: Hori, E., Nishijo, H., Ono, T.
  • 雑誌名: Nou to Shinkei 56 ページ: 109-120
  • NAID: 40019912260
  • 説明: 「研究成果報告書概要(欧文)」より
• [雑誌論文] Neural and molecular mechanisms of emotional learning in the amygdala. (2004)
  • 著者名/発表者名: Nishijo, H., Ono, T.
  • 雑誌名: Molecular Medicine 41 ページ: 1136-1148
  • 説明: 「研究成果報告書概要(欧文)」より
• [雑誌論文] Neural mechanisms for cognition of food reward and food (2004)
  • 著者名/発表者名: Nishijo, H., Tabuchi, E., Ono, T.
  • 雑誌名: Journal of Japan Society for the Study of Obesity 10 ページ: 4-11
  • 説明: 「研究成果報告書概要(欧文)」より
• [雑誌論文] A role of the amygdala in emotional expression and recognition of emotional responses expressed by other individuals (2004)
  • 著者名/発表者名: Tazumi, T., Nishijo, H., Ono, T.
  • 雑誌名: Japanese Psychological Review 47 ページ: 8-28
  • 説明: 「研究成果報告書概要(欧文)」より
• [雑誌論文] Neural mechanisms of emotion. In : Disorders of higher brain function. Eds ; Yanagisawa, N., Shinohara, Y, Iwata, M., Shimizu, T., Teramoto, A. (2004)
  • 著者名/発表者名: Hori, E., Nishijo, H., Ono, T.
  • 雑誌名: Annual Review Neuroscience ページ: 327-339
  • 説明: 「研究成果報告書概要(欧文)」より
• [雑誌論文] Effects of non-saponin fraction of red ginseng on learning deficits in aged rats. (2004)
  • 著者名/発表者名: Kurimoto, H., Nishijo, H., Uwano, T., Yamaguchi, H., Zhong, Y-M., Kawanishi, K., Ono, T.
  • 雑誌名: Physiol & Behav 82 ページ: 345-355
• [雑誌論文] Comparison of brain activity between dopamine d2 receptor-knockoutand wild mice in response to dopamine agonist and antagonist assessed by FMRI. (2004)
  • 著者名/発表者名: Kuriwaki, J., Nishijo, H., Kondoh, T., Uwano, T., Torii, K., Katsuki, M., Ono T.
  • 雑誌名: NeuroSignals 3 ページ: 227-240
• [雑誌論文] Neuronal correlates of face identification in the monkey anterior temporal cortical areas. (2004)
  • 著者名/発表者名: Eifuku, E., De, Souza, W.C., Tamura, R., Nishijo, H., Ono, T.
  • 雑誌名: J Neurophysiol 91 ページ: 358-371
• [雑誌論文] Effects of Choto-san and hooks and stems of Uncaria sinensis on antioxidant enzyme activities in the gerbil brain after transient forebrain ischemia. (2004)
  • 著者名/発表者名: Yokoyama, K., Shimada, Y., Hori, E., Nakagawa, T., Takagi, S., Sekiya, N., Kouta, K., Nishijo, H., Yokozawa, T., Terasawa K.
  • 雑誌名: JEthnopharmacol 95 ページ: 335-343
• [雑誌論文] Protective effects of choto-san and hooks and stem of Uncaria sinensis against delayed neuronal death after transient forebrain ischemia in gerbil. (2004)
  • 著者名/発表者名: Yokoyama, K., Shimada, Y., Hori, E., Sekiya, N., Goto, H., Sakakibara, I., Nishijo, H., Terasawa K.
  • 雑誌名: Phytomedicine 11 ページ: 478-489
• [雑誌論文] 双極子追跡法による視覚認知機能に関わる脳内電流発生源の推定 (2004)
  • 著者名/発表者名: 西条寿夫, 柴田孝, 小野武年
  • 雑誌名: 臨床脳波 12 ページ: 778-784
• [雑誌論文] 大脳機能の新しいパースペクティブ:社会的認知と情動発現 偏桃体と前頭葉の役割 (2004)
  • 著者名/発表者名: 堀悦郎, 西条寿夫, 小野武年
  • 雑誌名: 脳と神経 56 ページ: 109-120
• [雑誌論文] 自己の情動反応の表出と他個体の情動反応の認知における扁桃体の役割・動物を対象にした侵襲的脳研究の動向・ (2004)
  • 著者名/発表者名: 田積徹, 西条寿夫, 小野武年
  • 雑誌名: 心理学評論 47 ページ: 8-28
  • NAID: 130007631262
• [雑誌論文] Neuropsychological profile in patients with schizotypal personality disorder or schizophrenia. (2004)
  • 著者名/発表者名: Matsui, M., Sumiyoshi T., Kato, K., Yoneyama, E., Kurachi, M.
  • 雑誌名: Psychol Rep 94 ページ: 387-397
• [雑誌論文] Multiple structural brain measures obtained by three-dimensional MRI to distinguish between schizophrenia patients and normal subjects. (2004)
  • 著者名/発表者名: Nakamura, K., Kawasaki, Y., Suzuki, M., Hagino, H., Kurokawa, K., Takahashi, T., Niu, L., Matsui, M., Seto, H., Kurachi M.
  • 雑誌名: Schizophr Bull 30 ページ: 393-404
• [雑誌論文] Volume reduction of the amygdale in patients with schizophrenia a magnetic resonance imaging study. (2004)
  • 著者名/発表者名: Niu, L., Matsui, M., Zhou, S-Y., Hagino, H., Takahashi, T., Yoneyama, E., Kawasaki, Y., Suzuki, M., Seto, H., Ono, T., Kurachi, M.
  • 雑誌名: Psychiatry Res Neuroimaging 132 ページ: 41-51
• [雑誌論文] Effect of orthography on the verbal fluency performance in schizophrenia : Examination using Japanese patients. (2004)
  • 著者名/発表者名: Sumiyoshi, C., Sumiyoshi, T., Matsui, M., Nohara, S., Yamashita, I., Kurachi, M.
  • 雑誌名: Schizophr Res 69 ページ: 15-22
• [雑誌論文] Enhanced locomotor activity in rats with excitotoxic damage of the entorhinal cortex, a neurodevelopmental animal model of schizophrenia Behavioral : and in vivo microdialysis studies. (2004)
  • 著者名/発表者名: Sumiyoshi, T., Tsunoda, M., Uehara, T., Itoh, H., Tanaka, K., Sumiyoshi, C., Kurachi, M.
  • 雑誌名: Neurosci Lett 364 ページ: 124-129
• [雑誌論文] Volume reduction of the right anterior limb of the internal capsule in patients with schizotypal disorder. (2004)
  • 著者名/発表者名: Suzuki, M., Zhou, S-Y., Hagino, H., Takahashi, T., Kawasaki, Y., Nohara, S., Yamashita, I., Matsui, M., Seto, H., Kurachi, M.
  • 雑誌名: Psychiatry Res Neuroimaging 130 ページ: 213-225
• [雑誌論文] Bilateral volume reduction of the insular cortex in patients with schizophrenia a volumetric MRI study. (2004)
  • 著者名/発表者名: Takahashi, T., Suzuki, M., Hagino, H., Zhou, S-Y., Kawasaki, Y., Nohara, S., Nakamura, K., Yamashita, I., Seto, H., Kurachi, M.
  • 雑誌名: Psychiatry Res Neuroim aging 131 ページ: 185-194
• [雑誌論文] Lack of normal gender differences of the perigenual cingulate gyrus in schizophrenia spectrum disorders : a magnetic resonance imaging study. (2004)
  • 著者名/発表者名: Takahashi, T., Suzuki, M., Zhou, S-Y., Hagino, H., Kawasaki, Y., Yamashita, I., Nohara, S., Nakamura, K., Seto, H., Kurachi, K.
  • 雑誌名: Eur Arch Psychiatry Clin Neurosci 254 ページ: 273-280
• [雑誌論文] Enhancement of dopamine synthesis in the amygdale of rats with excitotoxic lesions of the left entorhinal cortex : an in vivo microdialysis study. (2004)
  • 著者名/発表者名: Uehara, T., Sumiyoshi, T., Itoh, H., Kurachi, M.
  • 雑誌名: Neurosci Lett 356 ページ: 21-24
• [雑誌論文] Decreased expression of REIC/DKK-3 in human renal clear cell carcinoma. (2004)
  • 著者名/発表者名: Kurose, K., Sakaguchi, M., Nasu, Y., Ebara, S., Kaku, H., Kariyama, R., Arao, Y., Miyazaki, M., Tsushima, T., Namba, M., Kumon, H., Huh, NH.
  • 雑誌名: J Urol 171(3) ページ: 1314-1318
• [雑誌論文] Propagation of adult rat bone marrow-derived hepatocyte-like cells by serial passages in vitro. (2004)
  • 著者名/発表者名: Miyazaki, M., Masaka, T., Akiyama, I., Nakashima, E., Sakaguchi, M., Huh, N.
  • 雑誌名: Cell Transplantation 13(4) ページ: 385-391
• [雑誌論文] PKCalpha mediates TGFbeta-induced growth inhibition of human keratinocytes viaphosphorylation ofS100C/A11. (2004)
  • 著者名/発表者名: Sakaguchi, M., Miyazaki, M., Sonegawa, H., Kashiwagi, M., Ohba, M., Kuroki, T., Namba, M., Huh, NH.
  • 雑誌名: J Cell Biol 164(7) ページ: 979-984
• [雑誌論文] Involvement of interferon regulatory factor 1 and S100C/A11 in growth inhibition by transforming growth factor beta 1 in human hepatocellular carcinoma cells. (2004)
  • 著者名/発表者名: Miyazaki, M., Sakaguchi, M., Akiyama, I., Sakaguchi, Y., Nagamori, S., Huh, NH.
  • 雑誌名: Cancer Res 64(12) ページ: 4155-4161
• [雑誌論文] Introduction of an N-terminal peptide of S100/A11 into human cells induces apoptotic cell death. (2004)
  • 著者名/発表者名: Makino, E., Sakaguchi, M., Iwatsuki, K., Huh, NH.
  • 雑誌名: J Mol Med 82(9) ページ: 612-620
• [雑誌論文] Novel collagen sponge reinforced with polyglycolic acid fiber produces robust, normal hair in murine hair reconstitution model. (2004)
  • 著者名/発表者名: Itoh, M., Hiraoka, Y., Kataoka, K., Huh, NH., Tabata, Y., Okochi, H.
  • 雑誌名: Tissue Eng 10(5-6) ページ: 818-824
• [雑誌論文] Increased expression of calcium-binding protein S100 in human uterine smooth muscle tumours. (2004)
  • 著者名/発表者名: Kanamori, T., Takakura, K., Mandai, M., Kariya, M., Fukuhara, K., Sakaguchi, M., Huh, NH., Saito, K., Sakurai, T., Fujita, J., Fujii, S.
  • 雑誌名: Mol Hum Reprod 10(10) ページ: 735-742
• [雑誌論文] Expression of CYP3A4 by an immortalized human hepatocyte line in a three-dimensional culture using a radial-flow bioreactor. (2004)
  • 著者名/発表者名: Akiyama, I., Tomiyama, K., Sakaguchi, M., Takaishi, M., Mori, M., Hosokawa, M., Nagamori, S., Shimizu, N., Huh, NH., Miyazaki, M.
  • 雑誌名: Int J Mol Med 14(4) ページ: 663-668
• [雑誌論文] Involvement of NF-kappa B in TGF-beta-mediated suppression of IL-4 signaling. (2004)
  • 著者名/発表者名: Yamamoto, T., Imoto, S., Sekine, Y., Sugiyama, K., Akimoto, T., Muraguchi, A., Matsuda, T.
  • 雑誌名: Biochem Biophys Res Commun 313 ページ: 627-634
• [雑誌論文] Activation of mouse RAG-2 promoter by Myc-associated zinc finger protein. (2004)
  • 著者名/発表者名: Wu, C-X., Zhao, W-P., Kishi, H., Dokan, J., Jin, Z-X., Wei, X-C., Yokoyama, K., Muraguchi, A.
  • 雑誌名: Biochem Biophys Res Commun 317 ページ: 1096-1102
• [雑誌論文] RGA protein associates with a TRPV ion channel during biosynthesis and trafficking. (2004)
  • 著者名/発表者名: Barnhill, Jc., Stokes, AJ., Koblan-Huberson, M., Shimoda, L.M., Muraguchi, A., Adra, CN., Turner, H.
  • 雑誌名: J Cell Biochem 91 ページ: 808-820
• [雑誌論文] Effects of prenatal maternal stress by repeated cold environment on behavioral and emotional development in the rat offspring.
  • 著者名/発表者名: Tazumi, T., Hori, E., Uwano, T., Umeno, K., Tanabe, K., Tabuchi, E., Ono, T., Nishijo, H.
  • 雑誌名: Behav Brain Res (In press)
• [雑誌論文] Effects of facial expression on shared attention mechanisms.
  • 著者名/発表者名: Hori, E., Tazumi, T, Tabuchi, E., Umeno, K., Kamachi, M., Ono, T., Nishijo, H.
  • 雑誌名: Physiol & Behav (In press)
• [雑誌論文] Effects of cadmium exposure during pregnancy on trace elements in fetal rat liver and kidney.
  • 著者名/発表者名: Kuriwaki, J., Nishijo, M., Honda, R., Tawara, K., Nakagawa, H., Hori, E., Nishijo, H.
  • 雑誌名: Toxicol Lett (In press)
• [雑誌論文] Structural brain differences in patients with schizophrenia and schizotypal disorder demonstrated by voxel-based morphometry.
  • 著者名/発表者名: Kawasaki, Y., Suzuki, M., Nohara, S., Hagino, H., Takahashi, T., Matsui, M., Yamashita, I., Chitnis, XA., McGuire, PK., Seto, H., Kurachi, M.
  • 雑誌名: Eur Arch Psychiatry Clin Neurosci (In press)
• [雑誌論文] Disorganization of semantic memory underlies alogia in schizophrenia ; An analysis of verbal fluency performance in Japanese subjects.
  • 著者名/発表者名: Sumiyoshi, C., Sumiyoshi, T., Nohara, S., Yamashita, I., Matsui, M., Kurachi, M.
  • 雑誌名: Schizophe Res (In press)
• [雑誌論文] Morphological brain changes associated with Schneider's first rank symptoms in schizophrenia : an MIR study.
  • 著者名/発表者名: Suzuki, M., Zhou, S-Y., Hagino, H., Niu, L., Takahashi, T., Kawasaki, Y., Matsusi, M., Seto, H., Ono, T., Kurachi, M.
  • 雑誌名: Psychol Med (In press)
• [雑誌論文] Relationship between exploratory eye movements and brain morphology in schizophrenia spectrum patients : voxel-based morphometry of three-dimensional magnetic resonance imaging.
  • 著者名/発表者名: Tsunoda, M., Kawasaki, Y., Matsui, M., Tonoya, Y., Hagino, H., Suzuki, M., Seto, H., Kurachi, M.
  • 雑誌名: Eur Arch Psychiatry Clin Neurosci (In press)
• [雑誌論文] Identification of human and its expression in regenerating and psoriatic skin.
  • 著者名/発表者名: Takaishi, M., Makino, T., Morohashi, M., Huh, NH.
  • 雑誌名: J Biol Chem (In press)
• [雑誌論文] An organic-inorganic hybrid scaffold for the culture of HepG2 cells in a bioreactor.
  • 著者名/発表者名: Kataoka, K., Nagao, Y., Nukui, T., Akiyama, I., Tsuru, K., Hayakawa, S., Osaka, A., Huh, NH.
  • 雑誌名: Biomaterials (In press)
• [雑誌論文] Expression of neurocan after transient middle cerebral artery occlusion in adult rat brain.
  • 著者名/発表者名: Deguchi, K., Takaishi, M., Hayashi, T., Oohira, A., Nagotani, S., Li, F., Jin, G., Nagano, I., Shoji, M., Miyazaki, M., Abe, K., Huh, NH.
  • 雑誌名: Brain Res (In press)
• [雑誌論文] Characterization of the proximal enhancer element and transcriptional regulatory factors for murine recombination activating gene-2.
  • 著者名/発表者名: Wei, X-C., Dohkan, J., Kishi, H., Wu, C-X., Kondo, S., Muraguchi, A.
  • 雑誌名: Eur J Immunol (In press)
• [雑誌論文] Doxorubicin induces expression of multidrag resistance-associated protein 1 in human small cell lung cancer cell lines by C-jun N-terminal kinase pathway.
  • 著者名/発表者名: Shinoda, C., Maruyama, M., Fujishita, T., Dohkan, J., Oda, H., Shinoda, K., Yamada, T., Miyadayashi, K., Hayashi, R., Kawagishi, Y., Fujita, T., Matsusi, S., Kashii, K., Sugiyama, E., Muraguchi, A., Kobayashi, M.
  • 雑誌名: International Journal of Cancer (In press)
• [図書] Annual Review神経2004 XVII.高次脳機能障害 2.情動の神経機構(柳澤信夫,篠原幸人,岩田 誠,清水輝夫,寺本 明編集) (2004)
  • 著者名/発表者名: 堀 悦郎, 西条寿夫, 小野武年
  • 総ページ数: 368
  • 出版者: 中外医学社
  • 説明: 「研究成果報告書概要(和文)」より
• [図書] Annual Review神経2004(柳澤信夫, 篠原幸人, 岩田 誠, 清水輝夫, 寺本 明編集) (2004)
  • 著者名/発表者名: 堀 悦郎, 西条寿夫, 小野武年
  • 出版者: 中外医学社,東京
• [文献書誌] Fukuda, Y., Yamamura, J., Uwano, T., Nishijo, H., Kurokawa, M., Fukuda, M., Ono, T., Shiraki, K.: "Regulated transgene delivery by ganciclovir in the brain without physiological alterations by a live attenuated herpes simplex virus vector."Neuroscience Res.. 45. 233-241 (2003)
• [文献書誌] Hori, F., Tabuchi, E., Matsumura, N., Tamura, R., Eifuku, S., Endo, S., Nishijo, H., Ono, T.: "Representation of place by monkey hippocampal neurons in real and virtual translocation."Hippocampus. 13. 190-196 (2003)
• [文献書誌] Kobayashi, T., Tran, A.H., Nishijo, H., Ono, T., Matsumoto, G.: "Contribution of hippocampal place cell activity to learning and formation of goal-directed navigation in rats."Neuroscience. 117. 1025-1035 (2003)
• [文献書誌] Umeno, K., Hori, E., Tabuchi, E., Takakura, H., Miyamoto, K., Ono, T., Nishijo, H.: "Gamma-band EEGs predict autonomic responses during mental arithmetic."Neuroreport. 14. 477-480 (2003)
• [文献書誌] Takakura, H., Umeno, K., Tabuchi, E., Hori, E., Miyamoto, K., Aso, S., Watanabe, Y., Ono, T., Nishijo, H.: "Differential activation in the medial temporal lobe during a sound-sequence discrimination task across age in human subjects."Neuroscience. 119. 517-532 (2003)
• [文献書誌] Asahi, T., Tamura, R., Eifuku, S., Hayashi, N., Endo, S., Nishijo, H., Ono, T.: "A method for determination of stereotoxic coordinates in single-unit recording studies in monkeys by high-resolution 3-dimensional magnetic resonance imaging."Neuroscience Res.. 47. 255-260 (2003)
• [文献書誌] Nishimura, F.T., Fukunaga, T., Yokomukai, Y., Kajiura, H., Ono, T., Nishijo, H.: "Age-dependent changes in electroencephalographic responses to alcohol consumption in subjects with aldehyde dehydrogenase-2 genetic variations."Alcohol Clin.Exp.Res.. 27. 841-848 (2003)
• [文献書誌] Dayawansa, S., Umeno, K., Takakura, H., Hori, E., Tabuchi, E., Nagashima, Y., Oosu, H., Yada, Y., Suzuki, T., Ono, T., Nishijo.H.: "Autonomic responses during inhalation of natural fragrance of "Cedrol" in humans."Autonomic Neuroscience : Basic and Clinical. 108. 79-86 (2003)
• [文献書誌] Nishijo, H., Hori, E., Ono, T.: "Role of the monkey amygdala in social cognition and non-verbal communication."J.Brain Sci.. 29. 10-15 (2003)
• [文献書誌] Eifuku, S., De Souza, W.C., Tamura, R., Nishijo, H., Ono, T.: "Neuronal correlates of face identification in the monkey anterior temporal cortical areas."J.Neurophysiol.. 91. 358-371 (2004)
• [文献書誌] Kuriwaki, J., Nishijo, H., Kondoh, T., Uwano, T., Torii, K., Katsuki, M., Ono, T.: "Comparison of brain activity between dopamine D2 receptor-knockout and wild mice in response to dopamine agonist and antagonist assessed by fMRI."NeuroSignals. in press.
• [文献書誌] 池本桂子, 上野照子, 石橋一寿, 永津郁子, 西村明儒, 西克治, 小野武年, 西条寿夫, 澁谷治男: "胎生期ストレスがカテコールアミン(CA)ニューロンの発達に与える影響:形態的アプローチ"脳と精神の科学. 14. 323-330 (2003)
• [文献書誌] 西条寿夫, 堀悦郎, 小野武年: "扁桃体における情動発現と非言語的コミュニケーション"神経心理学. 19. 145-155 (2003)
• [文献書誌] 田村了以, 小野武年: "快・不快の神経機構"脳の科学. 25. 247-255 (2003)
• [文献書誌] 小野武年, 田村了以: "大脳辺縁系,前頭前野および側坐核と情動行動"生体の科学. 印刷中.
• [文献書誌] Kurachi, M.: "Pathogenesis of schizophrenia : Part I. Symptomatology, cognitive characteristics and brain morphology."Psychiatry Clin.Neurosci.. 57. 3-8 (2003)
• [文献書誌] Kurachi, M.: "Pathogenesis of schizophrenia : Part II. Temporo-frontal two-step hypothesis."Phychiatry Clin.Neurosci.. 57. 9-16 (2003)
• [文献書誌] Tanaka, K., Yamamoto, T., Aikawa, Y., Kizawa, K., Muramoto, K., Matsuno, H., Muraguchi, A.: "Inhibitory effects of an anti-rhumatic agent T-614 on immunoglobulin production by cultured B cells and rheumatoid synovial tissues engrafted into SCID mice."Rheumatology. 42. 1365-1371 (2003)
• [文献書誌] Yotsutsuji, T., Saitoh, O., Suzuki, M., Hagino, H., Mori, K., Takahashi, T., Kurokawa, K., Matsui, M., Seto, H., Kurachi, M.: "Quantification of lateral ventricular subdivisions in schizophrenia by high-resolution three-dimensional MR imaging."Psychiatry Res.Neuroimaging. 122. 1-12 (2003)
• [文献書誌] Takahashi, T., Suzuki, M., Kawasaki, Y., Hagino, H., Yamashita, I., Nohara, S., Nakamura, K., Seto, H., Kurachi, M.: "Perigenual cingulate gyrus volume in patients with schizophrenia : a magnetic resonance imaging study."Biol.Psychiatry. 53. 593-600 (2003)
• [文献書誌] Zhou, S.-Y., Suzuki, M., Hagino, H., Takahashi, T., Kawasaki, Y., Nohara, S., Yamashita, I., Seto, H., Kurachi, M.: "Decreased volume and increased asymmetry of the anterior limb of the internal capsule in patients with schizophenia."Biol.Psychiatry. 54. 427-436 (2003)
• [文献書誌] Tonoya, Y., Matsui, M., Kurachi, M., Kurokawa, K., Sumiyoshi, T.: "Exploratory eye movements in schizophenia : effects of figure size and the instruction on visural search."Eur.Arch.Psychiatry Clin.Nerurosci.. 252. 255-261 (2003)
• [文献書誌] Yoneyama, E., Matsui, M., Kawasaki, Y., Nohara, S., Takahashi, T., Hagino, H., Suzuki, M., Seto, H., Kurachi, M.: "Gray matter features of schizotypal disorder patients exhibiting the schizophrenia-related code types of the Minnesota Multiphasic Personality Inventory."Acta Psychiatrica Scandinavica. 108. 333-340 (2003)
• [文献書誌] Uehara, T., Kurata, K., Sumiyoshi, T., Kurachi, M.: "Immobilization stress-induced increment of lactate metabolism in the basolateral amygdaloid nucleus is attenuated by diazepam in the rat."Eur.J.Pharmacol.. 459. 211-215 (2003)
• [文献書誌] Uchara, T., Kurata, K., Sumiyoshi, T., Kurachi, M.: "Modulation of stress-induced dopamine release by excitotoxic damage of the entorhinal cortex in the rat."Brain Res.. 989. 112-116 (2003)
• [文献書誌] Tanaka, K., Suzuki, M., Sumiyoshi, T., Murata, M., Tsunoda, M., Kurachi, M.: "Subchronic phencyclidine administration alters central vasopressin receptor binding and social interaction in rats."Brain Res.. 992. 239-245 (2003)
• [文献書誌] Uehara, T., Sumiyoshi, T., Itoh, H., Kurachi, M.: "Enhancement of dopamine synthesis in the amygdala of rats with excitotoxic lesions of the left entorhinal cortex ; an in vivo microdialysis study."Neurosci.Lett.. in press.
• [文献書誌] Sunmiyoshi, T., Jayathilake, K., Meltzer, H.Y.: "A comparison of two doses of melperone, an atypical antipsychotic drugs, in the treatment of schizophrenia."Schizophr.Res.. 62. 65-72 (2003)
• [文献書誌] Meltzer, H.Y., Sumiyoshi, T.: "Atypical antipsychotic drugs improve cognition in schizophrenia."Biol.Psychiatry. 53. 265-267 (2003)
• [文献書誌] Nakamura, K., Kawasaki, Y., Suzuki, M., Hagino, H., Kurokawa, K., Takahashi, T., Sha, N.-L., Matsui, M., Seto, H., Kurachi, M.: "Multiple structural brain measures obtained by three-dimensional MRI to distinguish between schizophrenia patients and normal subjects."Schizophr.Bull.. in press.
• [文献書誌] Takahashi, T., Suzuki, M., Zhou, S.-Y., Hagino, H., Kawasaki, Y., Yamashita, I., Nohara, S., Nakamura, K., Seto, H., Kurachi, K.: "Lack of normal gender differences of the perigenual cingulate gyruss in schizophrenia spectrum disorders : a magnetic resonance imaging study."Eur.Arch.Psychiatry Clin.Neurosci.. in press.
• [文献書誌] Suzuki, M., Zhou, S.-Y., Hagino, H., Takahashi, T., Kawasaki, Y., Nohara, S., Yamashita, I., Matsui, M., Seto, H., Kurachi, M.: "Volume reduction of the right anterior limb of the internal capsule in patients with schizotypal disorder."Psychiatry Res.Neuroimaging. in press.
• [文献書誌] 萩野宏文, 森光一, 高橋努, 鈴木道雄, 山下委希子, 黒川賢造, 野原茂, 四衢崇, 中村主計, 倉知正佳, 瀬戸光: "三次元磁気共鳴画像データを用いた脳サイズの解析:第1報 青年健常者における結果"脳の科学. 25. 357-363 (2003)
• [文献書誌] 萩野宏文, 高橋努, 鈴木道雄, 森光一, 山下委希子, 黒川賢造, 野原茂, 四衢崇, 中村主計, 倉知正佳, 瀬戸光: "三次元磁気共鳴画像データを用いた脳サイズの解析:第2報 統合失調症患者と健常者との比較"脳の科学. 25. 481-491 (2003)
• [文献書誌] Takaishi, M., Ishisaki, Z., Yoshida, T., Huh, N.: "Calmin, a novel actin-binding protein is a component of the postsynaptic density fraction of the mouse brain."Brain Res.Mol.Brain Res.. 112. 146-152 (2003)
• [文献書誌] Shibakura, M., Niiya, K., Kiguchi, T., Kitajima, I., Niiya, M., Asami, N., Huh, N., Nakata, Y., Harada, M., Tanimoto, M.: "Induction of interleukin-8 and monocyte chemoattractant protein-1 by doxorubicin in human small-cell lung carcinoma cells."Int.J.Cancer. 103. 380-386 (2003)
• [文献書誌] Makino, T., Takaishi, M., Toyoda, T., Morohashi, M., Huh, N.: "Expression of hornerin in stratified squamous epithelium in the mouse : A comparative analysis with profilaggrin."J.Histochem.Cytochem.. 51. 485-492 (2003)
• [文献書誌] Sakaguchi, M., Fukunishi, N., Teramoto, K., Miyazaki, M., Huh, N., Akagi, M.: "Involvement of arachidonic acid in nonimmunologic production of superoxide in mast cells."Int.Arch.Allergy.Immunol.. 130. 288-299 (2003)
• [文献書誌] Kataoka, K., Medina, R.I., Kageyama, T., Miyazaki, M., Yoshino, T., Makino, T., Huh, N.: "Participation of adult mouse bone marrow cells in reconstitution of skin."Am.J.Pathol.. 163. 1227-1231 (2003)
• [文献書誌] Nakajima, A., Kataoka, K., Hong, M., Sakaguchi, M, Huh, N.: "BRPK, a novel protein kinase showing increased expression in mouse cancer cell lines with higher metastatic potential."Cancer Lett.. 201. 195-201 (2003)
• [文献書誌] Sakaguchi, M., Miyazaki, M., Takaishi, M., Sakaguchi, Y., Makino, E., Kataoka, N., Yamada, H., Namba, M., Huh, N.: "S100C/All Is a key mediator of Ca^<++>-induced growth inhibition of human epidermal keratinocytes."J.Cell Biol.. 163. 825-835 (2003)
• [文献書誌] Kurose, K., Sakaguchi, M., Nasu, Y., Ebara, S., Kaku, H., Kariyama, R., Arao, Y., Miyazaki, M., Tushima, T., Namba, M., Kumon, H., Huh, N.: "Redued expression of REIC/Dkk-3 in human renal clear cell carcinoma."J.Urol.. 171:1. 134-138 (2004)
• [文献書誌] Miyazaki, M., Masaka, T., Akiyama, I.Nakashima, E., Sakaguchi, M, Huh, N.: "Propagation of adult rat bone marrow-derived hepatocyte-like cells by serial passages in vitro."Cell Transplantation. in press.
• [文献書誌] Sakaguchi, M., Miyazaki, M., Sonegawa, H., Kashiwagi, M., Ohba, M., Kuroki, T., Namba, M., Huh, N.: "PKCa mediates TGFβ-induced growth inhibition of human keratinocytes via phosphorylation of S100C/All."J.Cell Biol.. in press.
• [文献書誌] Yamamoto, T., Imoto, S., Sekine, Y., Sugiyama.K., Akimoto, T., Muraguchi, A., Natsuda, T.: "Involvement of NF-kB in TGF-β-mediated suppression of IL-4 signaling."Biochem.Biphys.Res.Comm.. 313. 627-634 (2003)
• [文献書誌] Liu, Q.-L., Kishi, H., Ohtsuka, K., Muraguchi, A.: "Heat shock protein 70 binds caspase-activated DNase and enhances its activity in TCR-stimulated T cells."Blood. 102. 1788-1796 (2003)
• [文献書誌] Kondo, S., Kishi, H., Tokimitsu, Y., Muraguchi, A.: "Possible involvement of glial cell line-derived neurotrophic factor and its recepter, GFRal, in survival and maturation of thymocytes."Eur.J.Immunol.. 33. 2233-2240 (2003)
• [文献書誌] Kawakami, T., Nagata, T., Muraguchi, A., Nishimura, T.: "Proteomic approach to apoptotic thymus maturation."J.Chromatography B.. 787. 223-229 (2003)
• [文献書誌] Eifuku, S., De Souza, W.C., Tamura, R., Nishijo, H., Ono, T.: "Cognition and Emotion in the Brain(On the organization of face memory)(T.Ono, G.Matsumoto, R.R.Llinas, A.Berthoz, R.Norgren, H.Nishijo, R.Tamura(Eds.))Amsterdam"Elsevier. 77-85 (2003)
• [文献書誌] Nishijo, H., Hori, E., Tazumi, T., Eifuku, S., Umeno, K., Tabuchi, E., Ono, T.: "Cognition and Emotion in the Brain(Role of the monkey amygdala in social cognition)(T.Ono, G.Matsumoto, R.R.Llinas, A.Berthoz, R.Norgren, H.Nishijo, R.Tamura(Eds.))Amsterdam"Elsevier. 295-310 (2003)
• [文献書誌] Komura, Y., Tamura, R., Uwano, T., Nishijo, H., Ono, T.: "Cognition and Emotion in the Brain(Transmodal coding for reward prediction in the audiovisual thalamus)(T.Ono, G.Matsumoto, R.R.Llinas, A.Berthoz, R.Norgren, H.Nishijo, R.Tamura(Eds.))Amsterdam"Elsevier. 383-396 (2003)
• [文献書誌] 堀 悦郎, 小野武年, 西条寿夫: "Annual Review神経(XVII.高次脳機能障害 2.情動の神経機構)(柳澤信夫, 篠原幸人, 岩田 誠, 清水輝夫, 寺本 明編集)東京"中外医学社. 327-339 (2004)
• [文献書誌] 小野武年, 西条寿夫: "新世紀の精神科治療6認知の科学と臨床(6.認知の神経回路基盤)(松下正明総編集, 岡崎祐士, 加藤 敏, 神庭重信, 新宮一成, 武田雅俊, 丹波真一, 山脇成人編集)東京"中山書店. 70-88 (2003)
• [文献書誌] 西条寿夫, 小野武年: "基礎栄養学 第5版(第10章 摂食行動)(吉田 勉編著)東京"医歯薬出版. 174-178 (2003)
• [文献書誌] Tran, A.H., Tamura, R, Uwano, T., Kobayashi, T., Katsuki, M., Matsumoto, G., Ono, T.: "Cognition and Emotion in the Brain(Dopamine D2 receptor-knockout changed accumbens neural response to prediction of reward associated with place in mice)(T.Ono, O.Matsumoto, R.R.Llinas, A.Berthoz, R.Norgren, H.Nishijo, R.Tamura(Eds.))Amsterdam"Elsevier. 493-508 (2003)
• [文献書誌] 小野武年, 上野照子: "脳神経科学(Neuroscience)(第6章認知機能の神経機構,7.情動)(伊藤正男監修, 金澤一郎, 篠田義一, 廣川信隆, 御子柴克彦, 宮下保司編集)東京"三輪書店. 753-770 (2003)
• [文献書誌] Li, R., Nishijo, H., Ono, T., Ohtani, Y., Ohtani, O.: "Synapses on GABAergic neurons in the basolateral nucleus of the rat amygdala: double-labeling immunoelectron microscopy"Synapse. 43. 42-50 (2002)
• [文献書誌] Hori, E., Uwano, T., Tamura, R., Miyake, N., Nishijo, H., Ono, T.: "Effects of a novel arginine-vasopressin derivative, NC-1900, on the spatial memory impairment of rats with transient forebrain ischemia"Cognitive Brain Res.. 13. 1-15 (2002)
• [文献書誌] Toyomitsu, Y., Nishijo, H., Uwano, T., Kuratsu, J., Ono, T.: "Neuronal responses of the rat amygdala during extinction and reassociation learning in the elementary and configural associative tasks"Eur. J. Neurosci.. 15. 753-768 (2002)
• [文献書誌] Tran, A.H., Tamura, R., Uwano, T., Kobayashi, T., Katsuki, M., Matsumoto, G., Ono, T.: "Altered accumbens neural response to prediction of reward associated with place in dopamine D2 receptor knockout mice"Proc. Natl. Acad. Sci. USA. 99. 8986-8991 (2002)
• [文献書誌] Tabuchi, E., Yokawa, T., Mallick, H., Inubushi, T., Kondoh, T., Ono, T., Torii, K.: "Spatio-temporal dynamics of brain activated regions during behavior in rats"Brain Res.. 951. 270-279 (2002)
• [文献書誌] Shibata, T., Nishijo, H., Tamura, R., Miyamoto, K., Eifuku, S., Endo, S., Ono, T.: "Generators of visual evoked potentials for faces and eyes in the human brain as determined by dipole localization"Brain Topography. 15. 51-63 (2002)
• [文献書誌] Hori, E., Tabuchi, E., Matsumura, N., Tamura, R., Eifuku, S., Endo, S., Nishijo, H., Ono, T.: "Representation of place by monkey hippocampal neurons in real and virtual translocation"Hippocampus. (in press).
• [文献書誌] Kobayashi, T., Tran, A.H., Nishijo, H., Ono, T., Matsumoto, G.: "Contribution of hippocampal place cell activity to learning and formation of goal-directed navigation in rats"Neuroscience. (in press).
• [文献書誌] Nishimura, F.T., Fukunaga, T., Kajiura, H., Umeno, K., Takakura, H., Ono, T., Nishijo, H.: "Effects of aldehyde dehydrogenase-2 genotype on cardiovascular and endocrine responses to alcohol in young japanese subjects"Autonomic Neuroscience : Basic and Clinical. (in press).
• [文献書誌] Nishimura, F.T., Fukunaga, T., Yokomukai, Y., kajiura, H., Ono, T., Nishijo, H.: "Age-dependent changes in electroencephalographic responses to alcohol consumption in subjects with aldehyde dehydrogenase-2 genetic variations"Alcoholism: Clin. and Exp. Res.. (in press).
• [文献書誌] Takakura, H., Umeno, K., Tabuchi, E., Hori, E., Miyamoto, K., Aso, S., Watanabe, Y., Ono, T., Nishijo, H.: "SDifferential activation in the medial temporal lobe during a sound-sequence discrimination task across age in human subjects"Neuroscience. (in press).
• [文献書誌] Umeno, K., Hori, E., Tabuchi, E., Takakura, H., Miyamoto, K., Ono, T., Nishijo, H.: "Gamma-band EEGs predict autonomic responses during mental arithmetic"NeuroReport. (in press).
• [文献書誌] 旭 雄士, 林 央周, 田村了以, 永福智志, 西条寿夫, 小野武年, 遠藤俊郎: "サル脳内ニューロン活動記録実験におけるMRI透瞭画像作製と軸補正の有用性-画像誘導手術支援システムの応用-"機能的脳神経外科. 41. 84-85 (2002)
• [文献書誌] 数井健一, 佐々木和男, 堀 悦郎, 田渕英一, 梅野克身, 小野武年, 西条寿夫: "仮想現実空間探索課題におけるサル海馬体ニューロンの応答性"信学技報(電子情報通信学会技術研究報告). MBE. 3-5 (2002)
• [文献書誌] Takahashi, T., kawasaki, Y., Kurokawa, K., Hagino, H., Nohara, S., Yamashita, I., Nakamura, K., Murata, M., Matsui, M., Suzuki, M., Seto, H., Kurachi, M.: "Lack of normal structural asymmetry of the anterior singulate gyrus in female patients with schizophrenia : a volumetric magnetic resonance imaging study"Schizophr. Res.. 55. 69-81 (2002)
• [文献書誌] Suzuki, M., Nohara, S., Hagino, H., Kurakawa, K., Yotsutsuji, T., Kawasaki, Y., Takahashi, T., matsui, M., Watanabe, N., Seto, H., Kurachi, M.: "Regional changes in brain gray and white matter in patients with schizophrenia demonstrated with voxel-based analysis of MRI"Schizophr. Res.. 55. 41-54 (2002)
• [文献書誌] Murata, M., Suzuki, M., Tanaka, K., Tajiri, K., Emori, K., Kurachi, M.: "N-methyl-D-aspartate-R1 receptor antisense oligodeoxynucleotide modulates pre-and postsynaptic expression of D2 dopamine receptors in the rat"Neurosci. Lett.. 335. 9-12 (2002)
• [文献書誌] Matsui, M., Sumiyoshi, T., Niu, L., Kurokawa, K., Kurachi, M.: "MMPI profile characteristics of schizotypal personality disorder"Psychiatry Clin. Neurosci.. 56. 443-452 (2002)
• [文献書誌] Matsui, M., Yoneyama, E., Sumiyoshi, T., Noguchi, K., Nohara, S., Suzuki, M., Kawasaki, Y., Seto, H., Kurachi, M.: "Lack of self-control as assessed by a personalitu inventory is related to reduced volume of supplementary motor area"Psychiatry Res. Neuroimaging. 116. 53-61 (2002)
• [文献書誌] Hagino, H., Suzuki, M., Mori, K., Nohara, S., Yamashita, I., Takahashi, T., Kurokawa, K., Matsui, M., Watanabe, N., Seto, H., Kurachi, M.: "Proton magnetic resonance spectroscopy of the inferior frontal gyrus and thalamus, and its relationship to verbal learning task performance in male patients with schizophrenia : a preliminary report"Psychiatry Clin. Neurosci.. 56. 449-507 (2002)
• [文献書誌] Kurachi, M.: "Pathogenesis of schizophrenia : PartI. Symptomatology, cognitive characteristics and brain morphology"Psychiatry Clin. Neurosci.. 57. 3-8 (2003)
• [文献書誌] Kurachi, M.: "Pathogenesis of schizophrenia : PartII. Temporo-frontal two-step hypothesis"Psychiatry Clin. Neurosci.. 57. 9-16 (2003)
• [文献書誌] Takahashi, T., Suzuki, M., Kawasaki, Y., Hagino, H., Yamashita, I., Nohara, S., Nakamura, K., Seto, H., Kurachi, M.: "Perigenual cingulated gyrus volume in patients with schizophrenia : a magnetic resonance imaging study"Biol. Psychiatry. (in press).
• [文献書誌] Takahashi, T., Suzuki, M., Kawasaki, Y., Kurokawa, K., Hagino, H., Yamashita, I., Zhou, S-Y., Nohara, S., Nakamura, K., Seto, H., Kurachi, M.: "Volumetric magnetic resonance imaging study of the anterior cingulated gyrus in schizotypal disorder"Eur. Arch. Psychiatry Clin. Neurosci.. (in press).
• [文献書誌] Tonoya, Y., Matsui, M., Kurachi, M., Kurokawa, K., Sumiyoshi, T.: "Exploratory eye movements in schizophrenia : effects of figure size and the instruction on visual search"Eur. Arch. Psychiatry Clin. Neurosci.. (in press).
• [文献書誌] Yotsutsuji, T., Saito, O., Suzuki, M., Hagino, H., Mori, K., Takahashi, T., Kurokawa, K., Matsui, M., Seto, H., Kurachi, M.: "Quantification of lateral ventricular subdivisions in schizophrenia by high-resolution three-dimensional MR imaging"Psychiatry Res. Neuroimaging. (in press).
• [文献書誌] Zhou, S-Y., Suzuki, M., Hagino, H., Takahashi, T., Kawasaki, Y., Nohara, S., Yamashita, I., Seto, H., Kurachi, M.: "Decreased Volume and Increased Asymmetry of the Anterior Limb of the Internal Capsule in Patients with Schizophrenia"Biol. Psychiatry. (in press).
• [文献書誌] 山下委希子, 松井三枝, 倉知正佳, 野原 茂, 高橋 努, 米山英一, 加藤 奏, 黒川賢造: "分裂病型障害患者と精神分裂病患者の神経心理学的プロフィールの比較"精神医学. 44. 845-851 (2002)
• [文献書誌] Kurokawa, M., Tsurita, M., Brown, J., Fukuda, Y., Shiraki, K.: "Effect of interleukin-12 level augmented by Kakkon-to, an herbal medicine, on the early stage of influenza infection in mice"Antiviral Res.. 56. 183-188 (2002)
• [文献書誌] Akanitapichat, P., Kurokawa, M., Tewtrakul, S., Pramyothin, P., Sripanidkulchai, B., Shiraki, K., Hattori, M.: "Inhibitory activities of Thai medicinal plants against herpes simplex type 1, poliovirus type 1, and measles virus"J. Traditional Med.. 19. 174-180 (2002)
• [文献書誌] Takasaki, I., Sasaki, A., Andoh, T., Nojima, H., Shiraki, K., Kuraishi, Y.: "Effects of analgesics on delayed postherpetic pain in mice"Anesthesiology. 96. 1168-1174 (2002)
• [文献書誌] Ohsaki, M., Kurokawa, M., Nawawi, A., Nakamura, N., Hattori, M., Shiraki, K.: "Characterization of anti-herpes simplex virus type 1 activity of an alkaloid FK 3000 from Stephania cepharantha"J. Traditional Med.. 19. 129-136 (2002)
• [文献書誌] Furuta, Y., Takahashi, K., Fukuda, Y., Kuno, M., Kamiyama, T., Kozaki, K., Nomura, N., Egawa, H., Minami, S., Watanabe, Y., Narita, H., Shiraki, K.: "In vitro and in vivo activities of anti-influenza viral compound T-705"Antimicrob. Agents Chemother.. 46. 977-981 (2002)
• [文献書誌] Phumiamorn, S., Sato, H., Kamiyama, T., Kurokawa, M., Shiraki, K.: "Induction of humoral and cell-mediated immunity to hepatitis B surface antigen by a novel adjuvant activity of Oka varicella vaccine"J. Gen. Virol.. 84. 287-291 (2003)
• [文献書誌] Fukuda, Y., Yamamura, J., Uwano, T., Nishijo, H., Kurokawa, M., Fukuda, M., Ono, T., Shiraki, K.: "Regulated transgene delivery by ganciclovir in the brain without physiological alterations by a live attenuated herpes simplex virus vector"Neuroscience Res.. 45. 233-241 (2003)
• [文献書誌] Kataoka, K., Huh, N.: "A novel b1, 3-N-acetylglucosaminyltransferase involved inÅ@invasion of cancer cells as assayed in vitro"Bichem. Biophys. Res. Commun.. 294(4). 843-848 (2002)
• [文献書誌] Ogawa, H., Gomi, T., Takusagawa, F., Masuda, T., Goto, T., Huh, N.: "Evidence for a dimeric structure of rat liver serine dehydratase"Int. J. Biochem. Cell Biol.. 34(5). 533-543 (2002)
• [文献書誌] Kondo, A., Sakaguchi, M., Makino, E., Namba, M., Okada, S., Huh, N.: "Localization of S100C immunoreactivity in various human tissues"Acta Med. Okayama. 56(1). 31-34 (2002)
• [文献書誌] Huh, W.K., Oono, T., Shirafuji, Y., Akiyam, H., Arata, J., Sakaguchi, M., Huh, N., Iwatsuki, K.: "Dynamic alteration of human β-defensin 2 localization from cytoplasm to intercellular space in psoriatic skin"J. Mol. Med.. 80(10). 678-684 (2002)
• [文献書誌] Miyazaki, M., Akiyama, I., Sakaguchi, M., Nakashima, E., Okada, M., kataoka, K., Huh, N.: "Improved conditions to induce hepatocytes from rat bone marrow cells in culture"Biochem. Biophys. Res. Commun.. 298(1). 24-30 (2002)
• [文献書誌] Shibakura, M., Niiya, K., Kiguchi, T., Kitajima, I., Niiya, M., Asami, N., Huh, N., Nakata, Y., Harada, M., Tanimoto, M.: "Induction of interleukin-8 and monocyte chemoattractant protein-1 by doxorubicin in human small-cell lung carcinoma cells"Int. J. Cancer. 103(3). 380-386 (2003)
• [文献書誌] Nakajima, A., Kataoka, K., Hong, M., Sakaguchi, M., Huh, N.: "BRPK, a novel protein kinase showing increased expression in mouse cancer cell lines with higher metastatic potential"Cancer Lett.. (in press).
• [文献書誌] Makino, T., Takaishi, M., Toyoda, T., Morohashi, M., Huh, N.: "Expression of Hornerin in Stratified Squamous Epithelium in the Mouse : A Comparative Analysis with Profilaggrin"J. Histochem. Cytochem.. (in press).
• [文献書誌] Takaishi, M., Ishisaki, Z., Yoshida, T., Huh, N.: "Expression of calmin, a novel developmentally regulated brain protein with calponin-homology domains"Mol. Brain Res.. (in press).
• [文献書誌] Kishi, H., Jin, Z-X., Wei, X-C., Nagata, T., Matsuda, T., Saito, S., Muraguchi, A.: "Cooperative binding of c-Myb and Pax-5 activates the RAG-2 promoter in immature B cells"Blood. 99. 576-583 (2002)
• [文献書誌] Nagata, T., Kishi, H., Liu, Q-L., Matsuda, T., Imanaka, T., Tsukada, K., Kang, D., muraguchi, A.: "The regulation of DNAse activities in subcellular compartments of activated thymocytes"Immunology. 105. 339-406 (2002)
• [文献書誌] Wei, X-C., Kishi, H., Zhao, W-P., Kondo, S., Matsuda, T., Saito, S., Muraguchi, A.: "Characterization of chromatin structure and enhancerelements for murine recombination activating gene-2"J. Immunol.. 169. 873-881 (2002)
• [文献書誌] Jin, Z-X., Kishi, H., Wei, X-C, Matsuda, T., Saito, S., Muraguchi, A.: "LEF-1 binds and activates the RAG-2 promoter together with c-Myb and Pax-5 in immature B cells"J. Immunol.. 169. 3783-3792 (2002)
• [文献書誌] 川崎康弘, 鈴木道雄, 中村主計, 倉知正佳: "形態画像.特集「臨床検査による精神科診断はどこまで可能となったか」"精神科診断学. 13(2). 145-152 (2002)
• [文献書誌] 許 南浩: "ES細胞"岡山医学会雑誌. 114(1). 59-61 (2002)
• [文献書誌] Nishijo, H., Hori, E., Tazumi, T., Eifuku, S., Umeno, K., Tabuchi, E., Ono, T.: "Role of the monkey amygdala in social cognition. In : Cognition and Emotion in the Brain"Elsevier (in press).
• [文献書誌] Eifuku, S., De Souza, W.C., Tamura, R., Nishijo, H., Ono, T.: "On the organization of face memory. In : Cognition and Emotion in the Brain"Elsevier (in press).
• [文献書誌] Tran, A.H., Tamura, R., Uwano, T., Kobayashi, T., Katsuki, M., Matsumoto, G., Ono, T.: "Dopamine D2 receptor-knockout changed accumbens neural response to prediction of reward associated with place in mice. In : Cognition and Emotion in the Brain"Elsevier (in press).
• [文献書誌] Komura, Y., Tamura, R., Uwano, T., Nishijo, H., Ono, T.: "Transmodal coding for reward prediction in the audiovisual thalamus. In : Cognition and Emotion in the Brain"Elsevier (in press).
• [文献書誌] 西条寿夫, 小野武年: "情動のメカニズムと大脳辺縁系 セラピストのための基礎研究論文集(4)「人間行動と皮質下機能」第3部大脳辺縁系と情動・動機づけ,永井洋一 編"協同医書出版社. 233-266 (2002)
• [文献書誌] 上野照子, 小野武年: "扁桃体と情動 セラピストのための基礎研究論文集(4)「人間行動と皮質下機能」第3部大脳辺縁系と情動・動機づけ, 永井洋一 編"協同医書出版社. 295-318 (2002)
• [文献書誌] 小野武年, 西条寿夫: "大脳辺縁系・大脳基底核における情と意の出力機構-本能, 情動, 生きる喜び-「情と意の脳科学-人とは何か」,1.情と意の脳神経構築,松本 元 小野武年 共編"培風館. 2-25 (2002)
• [文献書誌] 西条寿夫, 小野武年: "情と意における大脳辺縁系と連合野の役割-生物学的価値評価,行動戦略の決定-「情と意の脳科学-人とは何か」,1.情と意の脳神経構築,松本 元 小野武年 共編"培風館. 46-67 (2002)
• [文献書誌] 西条寿夫, 小野武年: "摂食行動 基礎 栄養学 第5版,吉田勉 編著"医歯薬出版. 174-178 (2003)
• [文献書誌] 小野武年, 上野照子: "情動 脳神経科学"三輪書店 (印刷中).
• [文献書誌] 田村了以, 小野武年: "快・不快の神経機構 脳の科学"星和書店 (印刷中).
• [文献書誌] Matsui, M., Yoneyama, E., Sumiyoshi, T., Noguchi, K., Nohara, S., Kurachi, M., Seto, H.: "Poor self-control in personality inventory and reduced volume of supplementary motor area. In Hirata, K.,Koga, Y.,Yamazaki, R.(eds.) Recent advances in human mapping : international congress series 1232"Elsevier. 131-135 (2002)
• [文献書誌] Matsui, M., Yoneyama, E., Sumiyoshi, T., Noguchi, K., Nohara, S., Seto, H., Kurachi, M.: "Lack of self-control in personality inventory and reduced volume of supplementary motor area. In Ogura, C.,Recent advances in early intervention and prevention in psychiatric disorders"Seiwa-Shoten. 268-269 (2002)
• [文献書誌] 倉知正佳, 川崎康弘: "統合失調症の病態形成と脳の発達 新世紀の精神科治療 第1巻 統合失調症の診断学"中山書店. 30-39 (2002)
• [文献書誌] 倉知正佳: "精神分裂病:自我と社会性の脳内機構. 「情と意の脳科学」,松本 元,小野武年共編"培風館. 174-189 (2002)
• [文献書誌] 許 南浩: "バイオ人工皮膚. 現代化学増刊「再生医学・再生医療」,室田誠逸編"東京化学同人. 211-213 (2002)
• [文献書誌] Yamaguchi, H., Tamura, R., Kuriwaki, J., Eifuku, S., Ono, T.: "Effects of T-588, a newly developed cognitive enhancer compound on synaptic plasticity in the dentate gyrus of freely moving rats"J.Pharmacol.Exp.Ther.. 298. 354-361 (2001)
• [文献書誌] Komura, Y., Tamura, R., Uwano, T., Nishijo, H., Kaga, K., Ono, T.: "Retrospective and prospective coding for predicated reward in the sensory thalamus"Nature. 412. 546-549 (2001)
• [文献書誌] Nakada, Y., Tamura, R., Kimura, T., Uwano, T., Nishijo, H., Ono, T.: "Ameliorative effects of a cognitive enhancer, T-588, on place learning deficits induced by transient forebrain ischemia in rats"Physiol.Behav.. 74. 1-9 (2001)
• [文献書誌] Nishimura, T.F., Fukunaga, T., Nishijo, H., Ono, T., Kajiura, H., Yokomukai, Y.: "Electroencephalogram spectral characteristics after alcohol ingestion in Japanese men with aldehyde dehydrogenase-2 genetic variations : comparison with perirheral changes. Alcohol"Clin.Exp.Res.. 25. 1030-1036 (2001)
• [文献書誌] Kamiyama, H., Kurimoto, M., Yamamura, J., Uwano, T., Hirashima, Y., Kurokawa, M., Endo, S., Shiraki, K.: "Effect of immunity on gene delivery into anterior horn motor neurons by live attenuated herpes simplex virus vector"Gene Ther.. 8. 1180-1187 (2001)
• [文献書誌] Li, R., Nishijo, H., Wang, Q., Uwano, T., Tamura, R., Ohtani, O., Ono, T.: "Light and electron microscopic study of cholinergic and noradrenergic elements in the basolateral nucleus of the rat amygdala : evidence for interactions between the two systems"J.Comp.Neurol.. 439. 411-425 (2001)
• [文献書誌] Ohtani, Y., Ohtani, O.: "Postnatal development of lymphatic vessels and their smooth muscle cells in the rat diaphragm : A confocal microscopic study"Arch.Histol.Cytol.. 106(Suppl.1,No.2). 251-259 (2001)
• [文献書誌] Yamamoto, T., Matsuda, T., Junicho, A., Kishi, H., Yoshimura, A., Muraguchi, A.: "Hematopoietic cell-specific adapter proteins, SLP-76 and BLNK, effectively activate NF-AT as well as NF-κB by Syk and Tec PTKs in non-lymphoid cell lines"FEBS Lett.. 491. 272-278 (2001)
• [文献書誌] Yamamoto, T., Matsuda, T., Muraguchi.A., Miyazono, K., Kawabata, M.: "Cross-talk between IL-6 and TGF-β signaling in hepatoma cells"FEBS Lett.. 492. 247-253 (2001)
• [文献書誌] Matsuda, T., Junicho, A., Yamamoto, T., Kishi, H., Korkimaz, K., Saatciogl u F., Fuse, H., Muraguchi, A.: "Cross-talk between signal transducer and activator of transcription 3 and androgen receptor signaling in prostate carcinoma cells"Biochem.Biophys.Res.Commun.. 283. 179-187 (2001)
• [文献書誌] Yoshino, T., Kishi, H., Nagata, T., Tsukada, K., Saito, S., Muraguchi, A.: "Differential involvement of p38 MAP kinase pathway and Bax translocation in the mitochondria-mediated cell death in TCR-and dexamethasone-stimulated thymocytes"Eur.J.Immunol.. 31. 2702-2708 (2001)
• [文献書誌] Matsuda, T., Yamamoto, T., Muraguchi, A., Saatcioglu, F.: "Cross-talk between transforming growth factor-β and estrogen receptor signa ling through Smad3"J.Biol.Chem.. 276. 42908-42914 (2001)
• [文献書誌] Ono, T., Nishijo, H.: "Hippocampal role in cognitive functions and memory, and effects of a novel cognitive enhancer on learning deficits due to hippocampal lesions"Psychogeriatrics. 1. 277-286 (2001)
• [文献書誌] Li, R.-X., Nishijo, H., Ono, T., Ohtani, Y., Ohtani, O.: "Synapses on GABAergic neurons in the basolateral nucleus of the rat amygdala : Double-labeling immunoeletron microscopy"Synapse. 43. 42-50 (2002)
• [文献書誌] Hori, E., Uwano, T., Tamura, R., Miyake, N., Nishijo, H., Ono, T.: "Effects of a novel arginine-vasopressin derivative, NC-1900, on the spatial memory impairment of rats whh transient forebrain ischemia"Cognitive Brain Res.. (in press). (2002)
• [文献書誌] Toyomitsu, Y., Nishijo, H., Uwano, T., Kuratsu, J., Ono, T.: "Neuronal responses of the rat amygdala during extinction and reassociation learning in the elementary and configural associative tasks"Eur.J.Neurosci.. (in press). (2002)
• [文献書誌] Hori, E., Tabuchi, E., Matsumura, N., Tamura, R., Eifuku, S., Endo, S., Nishijo, H., Ono, T.: "Representation of place by monkey hippocampal neurons in real and virtual translocation"Hippocampus. (in press). (2002)
• [文献書誌] 小野武年, 西条寿夫, 山口英俊, 上野照子: "ラット海馬体CA1錐体細胞層における細胞外集合スパイク電位に対する粗サポニン分画の抑制機構"The GINSENG REVIEW. 29. 22-29 (2002)
• [文献書誌] Sumiyoshi, T., Matsui, M., Yamashita, I., Nohara, S., Uehara, T., Kurachi, M., Sumiyoshi, S., Meltzer, H.Y.: "The effect of tandospirone, a serotonin 1 A agonist on memory function in schizophrenia"Biol. Psychiatry. 15. 861-868 (2001)
• [文献書誌] Sumiyoshi, C., Matsui, M., Sumiyoshi, T., Yamashita, I., Sumiyoshi, S., Kurachi, M.: "Semantic structure in schizophrenia as assessed by the category fluency test : effect of verbal intelligence and age of onset"Psychiatry Res.. (in press). (2002)
• [文献書誌] Murata, M., Kashiwa, A., Oshima, A., Umino, A., Kurachi, M., Nishikawa, T.: "Nomifensine-induced c-fos mRNA expression in discrete brain areas of the developing rat"Neuroscience Letters. 303. 99-102 (2001)
• [文献書誌] Tajiri, K., Emori, K., Murata, M., Tanaka, K., Suzuki, M., Uehara, T., Sumiyoshi.T., Kurachi, M., Ashby Jr., C.R.: "The intracerebroventricular administration of NMDA-Rl antisense oligodeoxynucleotide significantly alters the activity of ventral tegmental area dopamine neurons : an electrophysiological study"Synapse. 40. 275-281 (2001)
• [文献書誌] Kataoka, K., Nakajima, A., Takata, Y., Saito, S., Huh, N.: "Screening for genes involved in tissue invasion based on placenta formation and cancer cell lines with low and high metastatic potential"Cancer Lett.. 163(2). 213-219 (2001)
• [文献書誌] Jiang, H.X., Pu, H., Huh, N.H., Yokota, K., Oguma, K., Namba, M.: "Helicobacter pylori induces pepsinogen secretion by rat gastric cells in culture via a cAMP signal pathway"Int.J.Mol.Med.. 7(6). 625-629 (2001)
• [文献書誌] Aso, M., Suzuki, M., Kawasaki, Y., Hagino, H., Kurokawa, K., Yuasa, S., Kurachi, M.: "Sylvian fissure and inferior horn enlargement in patients with schizophrenia : A magnetic resonance imaging study"Psychiatry Clin.Neurosci.. 55. 49-56 (2001)
• [文献書誌] Hagino, H., Suzuki, M., Mori, K., Kurokawa, K., Yotsutsuji, T., Kurachi, M., Seto, H.: "Magnetic Resonance Imaging Study of Cavum Septi Pellucidi in Patients with Schizophrenia"Am.J.Psychiatry. 158. 1717-1719 (2001)
• [文献書誌] Takahashi, T., Kawasaki, Y., Kurokawa, K., Hagino.H., Nohara, S., Yamaishita, I., Nakamura, K., Murata, M., Matsui, M., Suzuki, M., Seto, H., Kurachi, M.: "Lack of normal structural asymmetry of the anterior cingulate gyrus in female patients with schizophrenia : a volumetric magnetic resonance imaging study"Schizophrenia Res.. (in press). (2002)
• [文献書誌] Suzuki, M., Nohara, S., Hagino, H., Yotsutsuji, T., Kurokawa, K., Kawasaki, Y., Matsui, M., Watanabe, N., Seto, H., Kurachi, M.: "Regional changes in brain gray and white matter in patients with schizophrenia demonstrated with voxel-based analysis of MRI"Schizophrenia Res.. (in press). (2002)
• [文献書誌] Matsui, M., Yoneyama, E., Sumiyoshi, T., Noguchi, K., Nohara, S., Suzuki, M., Kawasaki, Y., Seto, H., Kurachi, M.: "Lack of self-control as assessed by a personalitu inventory is related to reduced volume of supplementary motor area"Psychiatry Res.Neuroimaging. (in press). (2002)
• [文献書誌] Sumiyoshi, T., Matsui, M., Nohara, S., Yamashita, I., Kurachi, M., Sumiyoshi, C., Jayathilake, K., Meltzer, H.: "Addition of tandospirone to neuroleptic treatment enhances cognitive performance in schizophrenia"Am.J.Psychiatry. 158. 1722-1725 (2001)
• [文献書誌] Kamiyama, H., Kurimoto., M., Yamamura, J., Uwano, T., Hirashima, Y., Kurokawa, M., Endo, S., Shiraki K.: "Effect of immunity on gene delivery into anterior horn motor neurons by live attenuated herpes simplex virus vector"Gene Therapy. 8. 1180-1187 (2001)
• [文献書誌] Takasaki, I., Andoh, T., Nojima.H., Shiraki, K., Kuraishi, Y.: "Gabapentin antinociception in mice with acute herpetic pain induced by herpes simplex virus infection"J.Pharmcol.Experi.Therapeu.. 296. 70-75 (2001)
• [文献書誌] Honda, M., Okuda, T., Hasegawa, T., Kurokawa, M., Shiraki, K., Matsuo, K., Komatsuzaki, M., Niimura, M.: "Effect of long-term, low-dose acyclovir suppressive therapy on herpes simplex virus type 2 susceptibility to acyclovir and frequency of acyclovir-resistance"Antiviral Chem.Chemother. 12. 243-249 (2001)
• [文献書誌] Koti-Tsekpo, M.W., Rukunga, G.M., Kurokawa, M., Kageyama, S., Mungai, G.M., Muli, J.M., Muthaura, C.N., Kanyara, J.N., Tukei, P.M., Shiraki, K.: "An in vitro evaluation of extracts from some medicinal plants in Kenya against herpes simplex virus"Afri.J.Health Sci.. 8. 61-69 (2001)
• [文献書誌] Kamiyama, T., Kurokawa, M., Shiraki, K.: "Characterization of the DNA polymerase gene of varicella-zoster viruses むresistant to acyclovir"J.General Virol.. (in press). (2002)
• [文献書誌] Kageyama, S., Yamada, K., Kurimura, T., Shiraki, K.: "Polymorphism of CCR5 affecting HIV disease progression in the Japanese population"AIDS Res.Human Retroviruses. 17. 991-995 (2001)
• [文献書誌] Ishisaki, Z., Takaishi, M., Furuta, I., Huh, N.H.: "Calmin, a protein with calponin homology and transmembrane domains expressed in maturing spermatogenic cells"Genomics. 74(2). 172-179 (2001)
• [文献書誌] Yamago, G., Takata, Y., Furuta, I., Urase, K., Momoi, T., Huh, N.: "Suppression of hair follicle development inhibits induction of sonic hedgehog, patched, and patched-2 in hair germs in mice"Arch.Dermatol.Res.. 293(9). 435-441 (2001)
• [文献書誌] Niino, Y.S., Irie, T., Takaishi, M., Hosono, T., Huh, N., Tachikawa, T., Kuroki, T.: "PKC-II, a new isoform of potein kinase C specifically exrpessed in the seminiferous tubules of mosue testis"J.Biol.Chem.. 276(39). 36711-36717 (2001)
• [文献書誌] Kondo, A., Sakaguchi, M., Makino, E., Namba, M., Okada, S., Huh, N.: "Decrease in S100C expression in various human tissues after malignant transformation"Acta Med.Okayama. (in press). (2001)
• [文献書誌] Makino, T., Takaishi, M., Morohashi, M., Huh, N.: "Hornerin, a novel profi laggrin-like protein and differentiation-specitic marker isolated from mouse skin"J.Biol.Chem.. 276(50). 47445-47452 (2001)
• [文献書誌] Inoue, Y., Miyazaki, M., Tsuji, T., Sakaguchi, M., Fukaya, K., Huh, N.H., Namba, M.: "Reactivation of liver-specific gene expression in an immortalized human hepatocyte cell line by introduction of the human HNF4alpha2 gene"Int.J.Mol.Med.. 8(5). 481-487 (2001)
• [文献書誌] Yokoyama, T., Ayabe, S., Miyagi, H., Sugano, T., Otsu, A., Sato, H., Kageyama, S., Fujii, T., Shiraki, K.: "Varicella-zoster virus gH : gL contains a structure reactive with the anti-human gamma chain of IgG near the glycosylation site"J.General Virol.. 82. 331-334 (2001)
• [文献書誌] Kurokawa, M., Hozumi, T., Tsurita, M., Kadota, S., Namba, T., Shiraki, K.: "Biological characterization of eugeniin as an anti-herpes simplex virus type 1 compound in vitro and in vivo"J.Pharmacol.Experi.Therapeu.. 297. 372-379 (2001)
• [文献書誌] 田積徹, 小野武年, 西条寿夫: "不安の大脳生理学"分子精神医学. (印刷中).
• [文献書誌] Tsurita, M., Kurokawa, M., Imakita, M., Fukuda, Y., Watanabe, Y., Shiraki, K.: "Alleviation of influenza infection by early augmentation of interleukin (IL)-12 level in the airway of mice administered orally with clarithromycin or intranasally with IL-12"J.Pharmacol.Experi.Therapeu.. 298. 362-368 (2001)
• [文献書誌] Kamiya, N., Asano, Y., Yoshino, J., Sasaki, K., Honma, Y., Kawase, H., Yokochi, T., Shiraki, K., Tsuji, T.: "Long-term persistence of cellular immunity to Oka vaccine virus induced by pernasal co-administration with Escherichia coli enterotoxin in mice"Vaccine. 19. 3131-3136 (2001)
• [文献書誌] Shiraki, K., Sato, H., Yoshida, Y., Yamamura, J., Tsurita, M., Kurokawa, M., Kageyama, S.: "Construction of Oka varicella vaccine expressing human immunodeficiency virus env antigen"J.Medical Virol.. 64. 96-103 (2001)
• [文献書誌] Hasegawa, T., Kawana, T., Okuda, T., Tsukada, T., Horii, M., Shiraki, K.: "Analysis of herpes simplex virus isolated from the genital lesions since 1977 in Japan"J.Medical Virol.. 63. 57-63 (2001)
• [文献書誌] Takahashi, M., Kamiya, H., Asano, Y., Shiraki, K., Baba, K., Otsuka, T., Hirota, T., Yamanishi, K.: "Immunization of the elderly to boost immunity against varicella-zoster virus (VZV) as assessed by VZV skin test reaction"Archi.Virol.. (Suppl)17. 161-172 (2001)
• [文献書誌] Sasaki, K., Asano, Y., Honma, Y., Kamiya, N., Hanada, T., Ichinose, Y., Yokochi, T., Shiraki, K., Tsuji.T.: "Adjuvant action of Escherichia coli enterotoxin for delayed type hypersensitivity to Oka varicella virus on pernasal co-administration in mice"Vaccine. 19. 931-936 (2001)
• [文献書誌] Tamura, R., Ono, T.: "Neural substrate for spatial memory in the monkey hippocampus. In Neuroscientific Basis of Dementia, by Tanaka, C., McGeer, P.L.and Ihara, Y.(Ed.)"Birkhauser Verlag Basel, Switerland. 43-48 (2001)
• [文献書誌] 小野武年, 西条寿夫: "第7章 総合機能,B.情動と動機づけ,「標準生理学第5版」本郷利憲, 廣重力監修, 豊田順一, 熊田衛, 小澤靜司, 福田康一郎, 本間研一編集"医学書院,東京. 437-441 (2001)
• [文献書誌] 小野武年: "第6章 自律機能と本能行動,II.視床下部と辺縁系.「標準生理学第5版」本郷利憲, 廣重力監修, 豊田順一, 熊田衛, 小澤靜, 福田康一郎, 本間研一編集"医学書院,東京. 407-423 (2002)
• [文献書誌] 小野武年: "第2部 学ぶ脳,2.好きこそものの上手なれ.「育つ・学ぶ・癒す 脳図鑑21」伊藤正男序文,小泉英明編著"工作舎,東京. 237-270 (2001)
• [文献書誌] 小野武年, 西条寿夫: "第7章 総合機能,C.学習と記憶.「標準生理学第5版」本郷利憲, 廣重力監修, 豊田順一, 熊田衛, 小澤靜司, 福田康一郎, 本間研一編集"医学書院,東京. 441-446 (2001)
• [文献書誌] 小野武年, 西条寿夫: "大脳辺縁系・大脳基底核における情と意の出力機構-本能、情動、生きる喜び-「情と意の脳科学-人とは何か」松本 元編集"培風館,東京(印刷中). (2002)
• [文献書誌] 西条寿夫, 小野武年: "情と意における大脳辺縁系と連合野の役割-生物学的価値評価、行動戦略の決定-「情と意の脳科学-人とは何か」松本 元編集"培風館,東京(印刷中). (2002)
• [文献書誌] 上野照子, 小野武年: "第12章 扁桃体を情動.セラピストのための基礎研究論文集 (4)「人間行動と皮質下機能」第3部大脳辺縁系と情動・動機づけ、永井洋一編集"協同医書出版社,東京(印刷中). (2002)
• [文献書誌] 西条寿夫, 小野武年: "第10章 情動のメカニズムと大脳辺縁系.セラピストのための基礎研究論文集 (4)「人間行動と皮質下機能」第3部大脳辺縁系と情動・動機づけ、永井洋一編集"協同医書出版社,東京(印刷中). (2002)
• [文献書誌] 西条寿夫, 堀悦郎, 小野武年: "食物のおいしさと食欲の調節機構.「フードデザイン21」荒井綜,川端晶子,茂木信太郎,山野井昭雄編集"サイエンスフォーラム(株),東京(印刷中). (2002)
• [文献書誌] 小野武年: "情動,脳神経科学(Neuroscience)金澤一郎,篠田義一,廣川信隆,御子柴克彦,宮下保司 編集"三輪書店,東京(印刷中). (2002)
• [文献書誌] Yonemori,M.,Nishijo,H.,Uwano,T.,Tamura,R.,Furuta,I.,Kawasaki,M.,Takashima,Y.and Ono,T.: "Orbital cortex neuronal responses during an odor-based conditioned associative task in rats."Neuroscience. 95. 691-703 (2000)
• [文献書誌] Tanebe,K.,Nishijo,H.,Muraguchi,A.and Ono,T.: "Effects of chronic stress on hypothalamic interleukin-1β, interleukin-2, and gonadotropin-releasing hormone gene expression in ovariectomized rats."J.Neuroendocrinol.. 12. 13-21 (2000)
• [文献書誌] Tamura,R.,Nakada,Y.,Nishijo,H.,Miyake,N.and Ono,T.: "Ameliorative effects of tamolarizine on place learning impairment induced by transient forebrain ischemia in rats."Brain Res.. 853. 81-92 (2000)
• [文献書誌] Nishijo,H.,Ono,T.,Uwano,T.,Kondoh,T.and Torii,K.: "Hypothalamic and amygdalar neuronal responses to various tastant solutions during ingestive behavior in rats."J.Nutrition. 130. 9545-9595 (2000)
• [文献書誌] Kondoh,T.,Mori,M.,Ono,T.and Torii,K.: "Mechanisms of umami taste preference and aversion in rats."J.Nutrition. 130. 9665-9705 (2000)
• [文献書誌] Gejo,R.,Kawaguchi,Y.,Kondoh,T.,Tabuchi,E.,Matsui,H.,Torii,K.,Ono,T.and Kimura,T.: "Magnetic resonance imaging and histologic evidence of postoperative back muscle injury in rats."Spine. 25. 941-946 (2000)
• [文献書誌] Yamamura,J.,Kageyama,S.,Uwano,T.,Kurokawa,M.,Imakita,M.and Shiraki,K.: "Long-term gene expression in the anterior horn motor neurons after intramuscular inoculation of a live herpes simplex virus vector."Gene Therapy. 7. 934-941 (2000)
• [文献書誌] Zhong,Y.M.,Nishijo,H.,Uwano,T.,Tamura,R.,Kawanishi,K.and Ono,T.: "Red ginseng ameliorated place navigation deficits in young rats with hippocampal lesions and aged rats."Physiol.Behav.. 69. 511-525 (2000)
• [文献書誌] Ono,T.,Nishijo,H.and Nishino,H.: "Functional role of the limbic system and basal ganglia in motivated behaviors."J.Neurol.. 247. 23-32 (2000)
• [文献書誌] Martin,P.D.and Ono,T.: "Effects of reward anticipation,reward presentation, and spatial parameters on the firing of single neurons recorded in the subiculum and nucleus accumbens of freely moving rats."Behav.Brain Res.. 116. 23-38 (2000)
• [文献書誌] 小野武年,西条寿夫,上野照子,鐘咏梅: "老齢ラットの場所学習障害に対する非サポニン分画の改善効果."The GINSENG REVIEW. 28. 30-39 (2000)
• [文献書誌] 梅野克身,永嶋義直,高倉大匡,矢田幸博,堀悦郎,小野武年,西条寿夫: "暗算負荷中の呼吸循環動態および脳波の線形解析."自律神経. 37. 572-579 (2000)
• [文献書誌] Kataoka,K.,Takata,Y.,Nakajima,A.,Saito,S.and Huh,N.: "A carcinoembryonic antigen family cDNA from mouse placenta encoding a protein with a rare domain composition."Placenta. 21(7). 610-614 (2000)
• [文献書誌] Nakajima,A.,Kataoka,K.,Takata,Y.and Huh,N.: "Cathepsin-6, a novel cysteine proteinase showing homology with and co-localized expression with cathepsin J/P in the labyrinthine layer of mouse placenta."Biochem.J.. 349. 689-692 (2000)
• [文献書誌] Takata,S.,Ohtani,O.and Watanabe,Y.: "Lectin binding patterns in rat nasal-associated lymphoid tissue (NALT) and the influence of various types of lectin on particle uptake in NALT."Arch.Histol.Cytol.. 63(4). 305-312 (2000)
• [文献書誌] Ohtani,O.and Ohtani,Y.: "A corrosion casting/scanning electron microscope method that simul-taneously demonstrates clear outlines of endothelial cells and three-dimensional vascular organization."Arch.Histol.Cytol.. 63(5). 425-429 (2000)
• [文献書誌] Kamiyama,T.,Sato,H.,Takahara,T.,Kageyama,S.and Shiraki,K.: "Novel immunogenicity of Oka varicella vaccine vector expressing hepatitis B surface antigen."J.Infect.Dis.. 181. 1158-1161 (2000)
• [文献書誌] Takasaki,I.,Andoh,T.,Shiraki,K.and Kuraishi,Y.: "Allodynia and hyperalgesia induced by herpes simplex virus type-1 infection in mice."Pain. 86. 95-101 (2000)
• [文献書誌] Ida,M.,Kageyama,S.,Sato,H.,Kamiyama,T.,Toyomoto,T.,Ozaki,T.,Kajita,Y.,Morohashi,M.and Shiaki,K.: "Characterization of acyclovir susceptibility and genetic stability of varicella-zoster viruses isolated during acyclovir therapy."J.Dermatol.Sci.. 23. 63-72 (2000)
• [文献書誌] Imakita,M.,Shiraki,K.,Yutani,C.and Ishibashi-Ueda,H.: "Pneumonia caused by rhinovirus."Clin.Infect.Dis.. 30. 611-612 (2000)
• [文献書誌] Tsuji,T.,Shiraki,K.,Sato,H.,Yue-Mea,J.,Honma,Y.,Yoshikawa,T.and Asano,Y.: "Humoral immunoresponse to varicella-zoster virus pernasally coadministered with Escherichia coli enterotoxin in mice."Vaccine. 18. 2049-2054 (2000)
• [文献書誌] Yamamura,J.,Kageyama,S.,Uwano,T.,Kurokawa,M.and Shiraki,K.: "Long-term gene expression in the anterior horn motor neurons after intramuscular inoculation of a live herpes simplex virus vector."Gene Therapy. 7. 934-941 (2000)
• [文献書誌] Kageyama,S.,Maniar,J.K.,Iwasaki,M.,Zhang,J.,Saple,D.G.,Tsuchie,H.,Tanabe-Tochikura,A.,Taniguchi,K.,Shiraki,K.,and Kurimura,T.: "Seronegative HIV-2 carriers in India."Int.J.STD AIDS. 11. 31-37 (2000)
• [文献書誌] Kageyama,S.,Kurokawa,M.and Shiraki,K.: "Extract of Prunella vulgaris spikes inhibits HIV replication at reverse-transcription in vitro and can be absorbed from intestine in vivo."Antiviral Chem.Chemother. 11. 157-164 (2000)
• [文献書誌] Takasaki,I.,Andoh,T.,Nitta,M.,Takahata,H.,Nemoto,H.,Shiraki,K.,Nojima,H.and Kuraishi,Y.: "Pharmacological and immunohistochemical characterization of mouse model of acute herpetic pain."Jpn.J.Pharmacol.. 83. 319-326 (2000)
• [文献書誌] Sasaki,K.,Asano,Y.,Honma,Y.,Kamiya,N.,Imamura,S.,Ichinose,Y.,Yokochi,T.,Shiraki,K.and Tsuji,T.: "Adjuvant action of Escherichia coli enterotoxin for delayed-type hypersensitivity to Oka vaccine virus on pernasal co-administration in mice."Vaccine. 18. 2049-2054 (2000)
• [文献書誌] Hasegawa,T.,Kawana,T.,Okuda,T.,Tsukada,T.,Horii,M.and Shiraki,K.: "Analysis of herpes simplex virus isolated from the genital lesions since 1977 in Japan."J.Med.Virol.. 63. 57-63 (2001)
• [文献書誌] Sasaki,K.,Asano,Y.,Honma,Y.,Kamiya,N.,Hnada,T.,Ichinose,Y.,Yokochi,T.,Shiraki,K.and Tsuji,T.: "Adjuvant action of Escherichia coli enterotoxin for delayed type hypersensitivity to Oka varicella virus on pernasal co-administration in mice."Vaccine. 19. 931-936 (2001)
• [文献書誌] Yokoyama,T.,Ayabe,S.,Miyagi,H.,Sugano,T.,Otsu,A.,Sato,H.,kageyama,S.,Fujii,T.and Shiraki,K.: "Varicella-zoster virus gH : gL contains a structure reactive with the anti-human gamma chain of IgG near the glycosylation site."J.Gen.Virol.. 82. 331-334 (2001)
• [文献書誌] Shiraki,K.,Sato,H.,Yoshida,Y.,Yamamura,J.,Tsurita,M.,Kurokawa,M.and Kageyama,S.: "Construction of Oka varicella vaccine expressing human immunodeficiency virus env antigen."J.Med.Virol.. (in press). (2001)
• [文献書誌] KTakasaki,I.,Andoh,T.,Nojima,H.,Shiraki,K.and Kuraishi,Y.: "Gabapentin antinociception in mice with acute herpetic pain induced by herpes simplex virus infection."J.Pharmacol.Exp.Therapeut.. (in press). (2001)
• [文献書誌] Kurokawa,M.,Hozumi,T.,Tsurita,M.,Kadota,S.,Namba,T.and Shiraki,K.: "Biological characterization of eugeniin as an anti-herpes simplex virus type 1 compound in vitro and in vivo."J.Pharmacol.Exp.Therapeut.. (in press). (2001)
• [文献書誌] Kamiya,N.,Asano,Y.,Yoshino,J.,Sasaki,K.,Honma,Y.,Kawase H.,Yokochi,T.,Shiraki,K.and Tsuji,T.: "Long-term persistence of cellular immunity to Oka vaccine virus induced by pernasal co-administration with Escherichia coli enterotoxin in mice."Vaccine. (in press). (2001)
• [文献書誌] Fujishiro,Y.,Kishi,H.,Matsuda,T.,Fuse,H.and Muraguchi,A.: "Lactate dehydrogenase A-dependent surface expression of immature thymocyte antigen-1; an implication for a novel trafficking function of lactate dehydrogenase-A during T cell development."Eur.J.Immunol.. 30(2). 516-524 (2000)
• [文献書誌] Matsuda,T.,Yamamoto,T.,Kishi,H.,Yoshimura,A.and Muraguchi,A.: "SOCS-1 can suppress CD3ζ-and Syk-mediated NF-AT activation in a non-lymphoid cell line."FEB S Letters.. 472. 235-240 (2000)
• [文献書誌] Kawakami,T.,Nagata,T.,A.Muraguchi,A.and Nishimura,T.: "Alteration of protein composition in mouse thymocytes by signals through T-cell receptor."Electrophoresis.. 21. 1846-1852 (2000)
• [文献書誌] Kishi,H.,Wei,X.-C.,Jin,Z.-X.,Fujishiro,Y.,Nagata,T.,Matsuda,T.and Muraguchi,A.: "Lineage-specific regulation of the murine RAG-2 promoter : GATA-3 in T cells and Pax-5 in B cells."Blood.. 95. 3845-3852 (2000)
• [文献書誌] Nagata,T.,Kishi,H.,Liu,Q.-L.,Yoshino,T.,Matsuda,T.,Jin,Z.-X.,Murayama,K.,Tsukada,K.and Muraguchi,A.: "Possible involvement of cyclophilin B and caspase-activated deoxyribonuclease in the induction of chromosomal DNA degradation in TCR-stimulated thymocytes."J.Immunol.. 165. 4281-4289 (2000)
• [文献書誌] Junicho,A.,Matsuda,T.,Yamamoto,T.,Kishi,H.,Korkmaz,K.,Saatcioglu,F.,Fuse H.,and Muraguchi,A.: "Protein inhibitor of activated STAT3 regulates androgen receptor signaling in postate carcinoma cells."Biochem.Biophys.Res.Commun.. 278. 9-13 (2000)
• [文献書誌] Yamamoto,T.,Matsuda,T.,Junicho,A.,Kishi,H.,Saatcioglu,F.,and Muraguchi,A.: "Cross-talk between signal transducer and activator of transcription3 and estrogen receptorsignaling."FEB S Letters.. 486. 143-148 (2000)
• [文献書誌] Kurachi,M.,Sumiyoshi,T.,Shibata,R.,Sun,Y-J.,Uehara,T.,Tanii,Y.,and Suzuki,M.: "Changes in limbic dopamine metabolism following quinolinic acid lesions of the left entorhinal cortex in rats."Psychiatry Clin Neurosci.. 54. 83-89 (2000)
• [文献書誌] Uehara,T.,Tanii,Y.,Sumiyoshi,T.and Kurachi,M.: "Neonatal lesions of the left entorhinal cortex affect dopamine metabolism in the rat brain."Brain Res.. 860. 77-86 (2000)
• [文献書誌] 田村了以,小野武年: "情動."Clin.Neurosci.. 18. 910-911 (2000)
• [文献書誌] Kuroki,T.,Ikuta,T.,Kashiwagi,M.,Kawabe,S.,Ohta,M.,Huh,N.,Mizuno,K.,Ohno,S.,Yamada,E.,Chida,K.: "Cholesterol sulfate, an activator of protein kinase C mediating squamous cell differentiation. (a review)"Mutat.Res.. 62. 189-195 (2000)
• [文献書誌] 井上貴央,大谷修,村上宅郎: "走査電子顕微鏡."電子顕微鏡. 35. 132-135 (2000)
• [文献書誌] 長田拓哉,岸裕幸,松田正,村口篤: "胸腺T細胞のアポトーシス誘導とその制御."臨床免疫. 34. 424-433 (2000)
• [文献書誌] 倉知正佳,黒川賢造: "症状評価尺度の有用性とその問題点."精神科治療学. 15. 23-26 (2000)
• [文献書誌] 倉知正佳: "診断法の展望."Schizophr Frontier. 1. 12-17 (2000)
• [文献書誌] Nohara,S.,Suzuki,M.,Kurachi,M.,Yamashita,I.Matsui,M.,Seto,H.,and Saitoh,O.: "Neural correlates of memory organization deficits in schizophrenia-a single photon emission computed tomography study with 99mTc-ECD during a verbal learning task-."Schizophr.Res.. 42. 209-222 (2000)
• [文献書誌] Kurokawa,K.,Nakamura,K.,Hagino,H.,Yotsutsuji.T.,Yamashita,I.,Suzuki,M.,Sumiyoshi,T.,Matsui,M.and Kurachi,M.: "Ventricular Enlargement in Schizophrenic Patients with Prodromal Symptoms of Obsessive-Compulsive Disorder."Psychiatry Res.Neuroimaging. 99. 83-91 (2000)
• [文献書誌] Sumiyoshi,T.,Kurachi,M.,Kurokawa,K.,Yotsutsuji,T.,Uehara,T.,Itoh,H.and Saitoh,O.: "Plasma homovanillic acid in the prodromal phase of schizophrenia."Biol.Psychiatry. 47. 428-433 (2000)
• [文献書誌] Sumiyoshi,T.,Matsui,M.,Yamashita,I.,Nohara,S.,Uehara T.,Kurachi,M.and Meltzer,H.Y.: "Effect of adjunctive therapy with serotonin1A agonist tandospirone on memory functions in schizophrenia."J.Clin.Psychopharmacol.. 20. 386-388 (2000)
• [文献書誌] Sumiyoshi,T.,Kurachi,M.and Itoh,H.: "Schizophrenia and plasma homovanillic acid in response of plasma homovanillic acid to mental stress : methodological considerations."Neuropsychopharmacology. 23. 347-349 (2000)
• [文献書誌] 山下委希子,松井三枝,倉知正佳: "記憶の体制化を測る単語記憶検査の作成."精神医学. 42. 1279-1284 (2000)
• [文献書誌] 鈴木道雄,萩野宏文,野原茂,高橋努,山下委希子,倉知正佳: "アルツハイマー病の早期臨床診断における問題点."老年精神医学. 11. 1210-1219 (2000)
• [文献書誌] Tamura R,Kondoh T,Ono T,Nishijo H,Torii,K: "Altered activity of lateral and medial hypothalamic neurons in rats during discrimination of conditioned cue tone stimuli in repeated cold stress."J.Neurophysiol.. 84. 2844-2858 (2000)
• [文献書誌] Nakada Y,Tamura R,Kimura T,Uwano T,Nishijo H,Ono T.: "Ameliorative effects of a cognitive enhancer, T-588, on place learning deficits induced by transient forebrain ischemia in rats."Physiol.Behav.. (in press). (2000)
• [文献書誌] Nishimura FT,Fukunaga T,Nishijo H,Ono T,Kajiura H,Yokomukai Y: "EEG spectral characteristics after alcohol ingestion in Japanese men with aldehyde dehydrogenase-2 genetic variations : Comparison with peripheral changes."Alcoholism : Clinical and Experimental Research. (in press). (2000)
• [文献書誌] Tamura,R.and Ono,T.: "Neural substrate for spatial memory in the monkey hippocampus. In Neuroscientific Basis of Dementia, by C.Tanaka, Y.Ihara and P.L.McGeer (Eds.)"Birkhauser Verlag Basel : Switzerland. 43-49 (2001)
• [文献書誌] 田村了以,小野武年: "多連ガラス微小電極法.脳科学大事典(甘利俊一,外山敬介編集)I.総論8.脳の研究手法8.3"朝倉書店:東京. 75-79 (2000)
• [文献書誌] 田村了以,小野武年: "海馬体.脳科学大事典(甘利俊一,外山敬介編集)II.脳のシステム2.記憶と学習2.6"朝倉書店:東京. 187-195 (2000)
• [文献書誌] 西条寿夫,小野武年: "摂食行動.脳科学大事典(甘利俊一,外山敬介編集)II.脳のシステム4.行動,情動4.1本能行動,4.1.1"朝倉書店:東京. 234-244 (2000)
• [文献書誌] 西条寿夫,小野武年: "快・不快情動行動.脳科学大事典(甘利俊一,外山敬介編集)II.脳のシステム4.行動,情動4.2"朝倉書店:東京. 261-273 (2000)
• [文献書誌] 田村了以,小野武年: "脳幹.脳科学大事典(甘利俊一,外山敬介編集)II.脳のシステム4.行動,情動4.3行動の機能局在,4.3.1"朝倉書店:東京. 274-280 (2000)
• [文献書誌] 西条寿夫,小野武年: "辺縁系.脳科学大事典(甘利俊一,外山敬介編集)II.脳のシステム4.行動,情動4.3行動の機能局在,4.3.2"朝倉書店:東京. 281-292 (2000)
• [文献書誌] 小野武年: "うま味認知の脳内機構.グルタミン酸の科学-うま味から神経伝達まで(栗原堅三,小野武年,渡辺明治,林裕造 共著)第3章"講談社サイエンティフィック:東京. 49-92 (2000)
• [文献書誌] 小野武年: "脳における神経伝達物質としてのグルタミン酸.グルタミン酸の科学-うま味から神経伝達まで(栗原堅三,小野武年,渡辺明治,林裕造 共著)第4章"講談社サイエンティフィック:東京. 93-112 (2000)
• [文献書誌] 西条寿夫,小野武年: "自己定位と現実感.バーチャルリアリティの基礎1人工現実感の基礎"培風館:東京. 174-187 (2000)
• [文献書誌] 小野武年,西条寿夫,上野照子: "紅蔘の中枢神経作用に関する神経生理学的および行動学的研究.薬用人蔘2000(熊谷朗監修)"共立出版:東京. 66-82 (2000)
• [文献書誌] 大谷修,堀尾嘉幸: "カラー図解 人体の正常構造と機能 II循環器"日本医事新報社:東京. 1-102 (2000)
• [文献書誌] 大谷修: "SEM試料作製法.「電子顕微鏡 基礎技術と応用2000〜凍結技法で広がる超微の世界〜J.第11回電顕サマースクール実行委員会編"学際企画:東京. 78-87 (2000)
• [文献書誌] 大谷修: "線維成分観察法.「走査電子顕微鏡」日本電子顕微鏡学会関東支部編"共立出版:東京. 197-200 (2000)
• [文献書誌] 倉知正佳,鈴木道雄,齋藤治 編著: "神経科精神科卒後研修マニュアル.-疾患別治療ガイドライン"星和書店. 1-198 (2000)
• [文献書誌] 鈴木道雄,倉知正佳: "精神疾患への画像診断の応用.III.精神分裂病,C.SPECT,「臨床精神医学講座」,松下正明総編集,第S10巻,精神科臨床における画像診断"中山書店. 410-428 (2000)
• [文献書誌] 大谷修: "鋳型法.「走査電子顕微鏡」日本電子顕微鏡学会関東支部編"共立出版:東京. 204-209 (2000)
• [文献書誌] 倉知正佳: "精神疾患の動向.今日の治療指針.多賀須幸男,尾形悦郎総編集"医学書院. 265 (2000)