脳機能低下防止策としての筋活動の促進

• 研究課題/領域番号: 19100009
• 研究種目: 基盤研究(S)
• 配分区分: 補助金
• 研究分野: スポーツ科学
• 研究機関: 大阪大学
• 研究代表者: 大平 充宣 大阪大学, 医学系・研究科, 教授 (50185378)
• 研究分担者: 中井 直也 大阪大学, 医学系・研究科, 准教授 (90324508) ; 河野 史倫 大阪大学, 医学系・研究科, 助教 (90346156) ; 西本 憲弘 和歌山県立医科大学, 医学部, 教授 (80273663) ; 佐古田 三郎 大阪大学, 医学系・研究科, 教授 (00178625) ; 大海 忍 東京大学, 医科学研究所, 准教授 (20160046)
• 研究期間 (年度): 2007 – 2011
• 研究課題ステータス: 完了 (2011年度)
• 配分額: 116,350千円 (直接経費: 89,500千円、間接経費: 26,850千円); 2011年度: 19,110千円 (直接経費: 14,700千円、間接経費: 4,410千円); 2010年度: 19,110千円 (直接経費: 14,700千円、間接経費: 4,410千円); 2009年度: 27,560千円 (直接経費: 21,200千円、間接経費: 6,360千円); 2008年度: 23,270千円 (直接経費: 17,900千円、間接経費: 5,370千円); 2007年度: 27,300千円 (直接経費: 21,000千円、間接経費: 6,300千円)
• キーワード: 筋活動 / 脳機能 / 感覚神経 / プロテオミクス / 筋再生 / 骨格筋 / 脳 / プロテオーム / 遺伝子 / 再生

研究概要

後肢筋活動レベルが、ラットにおける脳機能やタンパク質発現等に及ぼす影響を追求する目的で、本研究が企画された。筋損傷は身体運動を抑制するので、損傷筋の再生を助長する方法を追求することも、大きな目的の一つである。その結果、後肢懸垂による抗重力活動の抑制は、新生ラットの正常な脳の発育を阻害した。さらに、損傷筋に温熱刺激を加えると、筋の再生が助長された。これらの筋には、(筋線維ではなく)毛細血管内に熱ショックタンパク質72(HSP72)を発現する細胞が見られた。これらの細胞は、骨髄細胞または白血球であり、HSP72が、間接的に筋再生を刺激することが示唆された。遺伝子およびタンパク質発現にも、温熱刺激特異的な影響が確認された。

研究成果

• [雑誌論文] HSP25 can modulate myofiber desmin cytoskeleton following the phosphorylation at Ser15 in rat soleus muscle (2012)
  • 著者名/発表者名: Kawano, F., R. Fujita, N. Nakai, M. Terada, T. Ohira, and Y. Ohira
  • 雑誌名: J. Appl. Physiol 巻: 112 ページ: 176-186
• [雑誌論文] Regional neural activation defines a gateway for autoreactive T cells to cross the blood-brain barrier (2012)
  • 著者名/発表者名: Arima, Y., M. Harada, D. kamimura, J-H. Park, F. Kawano, F. E. Yull. T. Kawamoto, Y. Iwakura, U. A. K. Betz, G. Marquez, T. S. Blackwell, Y. Ohira, T. Hirano, and M. Murakami
  • 雑誌名: Cell 巻: 148 ページ: 447-457
• [雑誌論文] Biomedical analysis of rat body hair after hindlimb suspension for 14 days (2012)
  • 著者名/発表者名: Terada, M., F. Kawano, N. Ishioka, A. Higashibata, H. J. Majima, T. Yamazaki, T. Watanabe-Asaka, M. Niihori, R. Nakano, S. Yamada, C. Mukai, and Y. Ohira
  • 雑誌名: Acta Astronautica 巻: 73 ページ: 23-29
• [雑誌論文] Effects of hindlimb unloading on neurogenesis in the hippocampus of newly weaned rats (2012)
  • 著者名/発表者名: Nomura, S., K. Kami, F. Kawano, Y. Oke, N. Nakai, T. Ohira, R. Fujita, M. Terada, K. Imaizumi, and Y. Ohira
  • 雑誌名: Neurosci. Lett 巻: 509 ページ: 76-81
• [雑誌論文] Adaptation of mouse skeletal muscle to long-term microgravity in the MDS mission (2012)
  • 著者名/発表者名: Sandona, D., J.-F. Desaphy, G. M. Camerino, E. Bianchini, S. Ciciliot, D. Danieli-Betto, G. Dobrowolny, S. Furlan, E. Germinario, K. Goto, M. Gutsmann, F. Kawano, N. Nakai, T. Ohira, Y. Ohno, A. Picard, M. Salanova, G. Schiffl, D. Blottner, A. Musaro, Y.
  • 雑誌名: PloS ONE 巻: 7
• [雑誌論文] The impact of long-term exposure to space environment on adult mammalian organisms : a study on mouse thyroid and testis (2012)
  • 著者名/発表者名: Masini, M. A., E. Albi, C. Barmo, T. Bonfiglio, L. Bruni, L. Canesi, S. Cataldi, F. Curcio, M. D' Amora, I. Ferri, K. Goto, F. Kawano, R. Lazzarini, E. Loreti, N. Nakai, T. Ohira, Y. Ohira, S. Palmero, P. Prato, F. Ricci, L. Scarabelli, T. Shibaguchi, R.
  • 雑誌名: PloS ONE 巻: 7
• [雑誌論文] Adaptation of mouse skeletal muscle to long-term microgravity in the MDS mission (2012)
  • 著者名/発表者名: Sandona, D., J.-F.Desaphy, G.M.Camerino, E.Bianchini, S.Ciciliot, D.Danieli-Betto, G.Dobrowolny, S.Furlan, E.Germinario, K.Goto, M.Gutsmann, F.Kawano, N.Nakai, T.Ohira, Y.Ohno, A.Picard, M.Salanova, G.Schiffl, D.Blottner, A.Musaro, Y.Ohira, R.Betto, D.Conte, S.Schiaffino
  • 雑誌名: PloS ONE 巻: 7
  • 査読あり
• [雑誌論文] HSP25 can modulate myofiber desmin cytoskeleton following the phosphorylation at Ser15 in rat soleus muscle (2012)
  • 著者名/発表者名: Kawano, R, R.Fujita, N.Nakai, M.Terada, T.Ohira, Y.Ohira
  • 雑誌名: J.Appl.Physiol. 巻: 112 ページ: 176-186
  • 査読あり
• [雑誌論文] Effects of hindlimb unloading on neurogenesis in the hippocampus of newly weaned rats (2012)
  • 著者名/発表者名: Nomura, S., K.Kami, F.Kawano, Y.Oke, N.Nakai, T.Ohira, R.Fujita, M.Terada, K.Imaizumi, Y.Ohira
  • 雑誌名: Neurosci.Lett. 巻: 509 ページ: 76-81
  • 査読あり
• [雑誌論文] Responses of muscle mass, strength and gene expressions to long-term heat stress in healthy human subjects (2011)
  • 著者名/発表者名: Goto, K., H. Oda, H. Kondo, M. Igaki, A. Suzuki, S. Tsuchiya, T. Murase, T. Hase, H. Fujiya, I. Matsumoto, H. Naito, T. Sugiura, Y. Ohira, and T. Yoshioka
  • 雑誌名: Eur. J. Appl. Physiol 巻: 111 ページ: 17-27
• [雑誌論文] Possible role of NF-. B signals in heat stress-associated increase in protein content of cultured C2C12 cells (2011)
  • 著者名/発表者名: Ohno, Y., S. Yamada, T. Sugiura, Y. Ohira, T. Yoshioka, and K. Goto
  • 雑誌名: Cells Tissues Organs 巻: 194 ページ: 363-370
• [雑誌論文] Effects of creatine and its analog,.-guanidinopropionic acid, on the differentiation and nucleoli in myoblasts. Biosci (2011)
  • 著者名/発表者名: Ohira, Y., Y. Matsuoka, F. Kawano, A. Ogura, Y. Higo, T. Ohira, M. Terada, Y. Oke, and N. Nakai
  • 雑誌名: Biotechnol. Biochem 巻: 75 ページ: 1085-1089
• [雑誌論文] Region-specific responses of adductor longus muscle to gravitational load-dependent activity in Wistar Hannover rats (2011)
  • 著者名/発表者名: Ohira, T., X. D. Wang, M. Terada, F. Kawano, N. Nakai, A. Ogura, and Y. Ohira
  • 雑誌名: PLoS ONE 巻: 6
• [雑誌論文] Absence of heat shock transcription factor 1 retards the regrowth of atrophied soleus muscle in mice (2011)
  • 著者名/発表者名: Yasuhara, K., Y. Ohno, A. Kojima, K. Uehara, M. Beppu, T. Sugiura, M. Fujimoto, A. Nakai, Y. Ohira, T. Yoshioka, and K. Goto
  • 雑誌名: J. Appl. Physiol 巻: 111 ページ: 1142-1149
• [雑誌論文] 3ヶ月の宇宙基地滞在がマウスの生理学的特性に及ぼす影響:宇宙実験のコントロールとしての地上シミュレーション実験 (2011)
  • 著者名/発表者名: 大平充宣、中井直也、河野史倫、大平宇志、芝口翼、藤田諒、後藤勝正、石原昭彦、大石康晴、山崎将生、向井千秋、寺田昌弘、山下雅道、宇佐美眞一、奥野誠、落合俊昌、行徳淳一郎
  • 雑誌名: Space Utiliz. Res 巻: 27 ページ: 122-123
  • NAID: 120006830349
• [雑誌論文] 哺乳類小動物を用いた宇宙生物学実験 (2011)
  • 著者名/発表者名: 山崎将生、大平充宣、奥野誠、石原昭彦、清水強、粂井康宏、伊藤康宏、野村裕子、高林彰、大西武雄、片平清昭、矢野昭起、中野完、山下雅道
  • 雑誌名: Space Utiliz. Res 巻: 27 ページ: 124-126
• [雑誌論文] 宇宙環境での疾病と健康管理-2010年(第1年度)研究チーム活動報告- (2011)
  • 著者名/発表者名: 石原昭彦、津田謹輔、神埼素樹、永友文子、藤野英己、平田総一郎、三浦靖史、村上慎一郎、近藤浩代、武田功、大平充宣
  • 雑誌名: Space Utiliz. Res 巻: 27 ページ: 142-144
• [雑誌論文] 尾部懸垂の精子形成における影響 (2011)
  • 著者名/発表者名: 奥野誠、向井千夏、大平充宣
  • 雑誌名: Space Utiliz. Res 巻: 27 ページ: 203-204
  • NAID: 120006830380
• [雑誌論文] 健康の維持・増進を目指した運動処方のヒトおよびラットにおける再検討 (2011)
  • 著者名/発表者名: 大平充宣、中井直也、岡部洋興、陳全寿
  • 雑誌名: デサントスポーツ科学 巻: 32 ページ: 11-18
  • NAID: 40018886187
• [雑誌論文] 筋機能からみた萎縮と肥大のメカニズム (2011)
  • 著者名/発表者名: 後藤勝正、大平充宣
  • 雑誌名: 体育の科学別冊61 巻: 12 ページ: 900-906
• [雑誌論文] Responses of muscle mass, strength and gene expressions to long-term heat stress in healthy human subjects (2011)
  • 著者名/発表者名: Goto, K., H.Oda, H.Kondo, M.Igaki, A.Suzuki, S.Tsuchiya, T.Murase, T.Hase, H.Fujiya, I.Matsumoto, H.Naito, T.Sugiura, Y.Ohira, T.Yoshioka
  • 雑誌名: Eur.J.Appl.Physiol. 巻: 111 ページ: 17-27
  • 査読あり
• [雑誌論文] Possible role of NF-κB signals in heat stress-associated increase in protein content of cultured C2C12 cells (2011)
  • 著者名/発表者名: Ohno, Y., S.Yamada, T.Sugiura, Y.Ohira, T.Yoshioka, K.Goto
  • 雑誌名: Cells Tissues Organs 巻: 194 ページ: 363-370
  • 査読あり
• [雑誌論文] Effects of creatine and its analog, β-guanidinopropionic acid, on the differentiation and nucleoli in myoblasts (2011)
  • 著者名/発表者名: Ohira, Y., Y.Matsuoka, F.Kawano, A.Ogura, Y.Higo, T.Ohira, M.Terada, Y.Oke, N.Nakai
  • 雑誌名: Biosci.Biotechnol.Biochem. 巻: 75 ページ: 1085-1089
  • NAID: 10029327954
  • 査読あり
• [雑誌論文] Region-specific responses of adductor longus muscle to gravitational load-dependent activity in Wistar Hannover rats (2011)
  • 著者名/発表者名: Ohira, T., X.D.Wang, M.Terada, F.Kawano, N.Nakai, A.Ogura, Y.Ohira
  • 雑誌名: PLoS ONE 巻: 6
  • 査読あり
• [雑誌論文] Absence of heat shock transcription factor 1 retards the regrowth of atrophied soleus muscle in mice (2011)
  • 著者名/発表者名: Yasuhara, K., Y.Ohno, A.Kojima, K.Uehara, M.Beppu, T.Sugiura, M.Fujimoto, A.Nakai, Y.Ohira, T.Yoshioka, K.Goto
  • 雑誌名: J.Appl.Physiol. 巻: 11 ページ: 1142-1149
  • 査読あり
• [雑誌論文] Myonucleus-related properties in soleus muscle fibers of mdx mice (2010)
  • 著者名/発表者名: Terada, M., Y. B. Lan. F. Kawano, T. Ohira, Y. Higo, N. Nakai, K. Imaizumi, A. Ogura, N. Nishimoto, Y. Adachi, and Y. Ohira
  • 雑誌名: Cells Tissues Organs 巻: 191 ページ: 248-259
• [雑誌論文] Role(s) of gravitational loading during developing period on the growth of rat soleus muscle fibers (2010)
  • 著者名/発表者名: Kawano, F., K. Goto, X. D. Wang, M. Terada, T. Ohira, N. Nakai, T. Yoshioka, and Y. Ohira
  • 雑誌名: J. Appl. Physiol 巻: 108 ページ: 676-685
• [雑誌論文] A possible role of NF-. B and HSP72 in skeletal muscle hypertrophy induced by heat stress in rats (2010)
  • 著者名/発表者名: Ohno, Y., S. Yamada, T. Sugiura, Y. Ohira, T. Yoshioka, and K. Goto
  • 雑誌名: Gen. Physiol. Biophys 巻: 29 ページ: 234-242
• [雑誌論文] Role(s) of mechanical load and satellite cells in the regulation of the size of soleus muscle fiber in rats (2010)
  • 著者名/発表者名: Ohira, Y., F. Kawano, X. D. Wang, N. Nakai, T. Ohira, H. Okabe, H. Naito, and K. Goto
  • 雑誌名: Biol. Sci. Space 巻: 24 ページ: 135-144
  • NAID: 10029277900
• [雑誌論文] Mechanical stretch activates signaling events for protein translation initiation and elongation in C2C12 myoblasts (2010)
  • 著者名/発表者名: Nakai, N., F. Kawano, Y. Oke, S. Nomura, T. Ohira, R. Fujita, and Y. Ohira
  • 雑誌名: Mol. Cells 巻: 30 ページ: 513-518
• [雑誌論文] 体位変換による血液分布の変化が運動能力に及ぼす影響:自転車エルゴメーター運動中の制限因子の検討 (2010)
  • 著者名/発表者名: 川畑哲也、岡部洋興、大平宇志、河野史倫、内藤久士、大平充宣
  • 雑誌名: 宇宙航空環境医学 巻: 47 ページ: 15-22
  • NAID: 10029518929
• [雑誌論文] 発育期の脚運動がラット脳の発育・発達に及ぼす影響 (2010)
  • 著者名/発表者名: 大平充宣、野村幸子、尾家慶彦、大平宇志、河野史倫、藤田諒、中井直也、今泉和彦
  • 雑誌名: 早稲田大学人間科学学術院「人間科学研究」 巻: 第23巻第1号補遺号 ページ: 127-127
  • NAID: 120005260316
• [雑誌論文] Myonucleus-related properties in soleus muscle fibers of mdx mice (2010)
  • 著者名/発表者名: Terada M., et al
  • 雑誌名: Cell Tissues Organs 巻: 191 ページ: 248-259
  • 査読あり
• [雑誌論文] A possible role of NF-κB and HSP72 in skeletal muscle hypertrophy induced by heat stress in rats (2010)
  • 著者名/発表者名: Ohno, Y., et al
  • 雑誌名: Gen.Physiol.Biophys. 巻: 29 ページ: 234-242
  • 査読あり
• [雑誌論文] Role(s) of gravitational loading during developing period on the growth of rat soleus muscle fibers (2010)
  • 著者名/発表者名: Kawano, F., et al
  • 雑誌名: J.Appl.Physiol. 巻: 108 ページ: 676-685
  • 査読あり
• [雑誌論文] Role(s) of mechanical load and satellite cells in the regulation of the size of soleus muscle fiber in rats (2010)
  • 著者名/発表者名: Ohira, Y., et al
  • 雑誌名: Biol.Sci.Space 巻: 24 ページ: 135-144
  • 査読あり
• [雑誌論文] Mechanical stretch activates signaling events for protein translation initiation and elongation in C2C12 myoblasts (2010)
  • 著者名/発表者名: Nakai, N., et al
  • 雑誌名: Mol.Cells 巻: 30 ページ: 513-518
  • 査読あり
• [雑誌論文] Responses of muscle mass, strength and gene expressions to long-term heat stress in healthy human subjects (2010)
  • 著者名/発表者名: Goto, K., et al
  • 雑誌名: Eur.J.Appl.Physiol. 巻: 111 ページ: 17-27
  • 査読あり
• [雑誌論文] Possible role of NF-κB signals in heat stress-associated increase in protein content of cultured C2C12 cells (2010)
  • 著者名/発表者名: Ohno, Y., et al
  • 雑誌名: Cells Tissues Organs 巻: 194 ページ: 363-370
  • 査読あり
• [雑誌論文] Myonucleus-related properties in soleus muscle fibers of mdx mice (2010)
  • 著者名/発表者名: Terada, M., Y. B. Lan. F. Kawano, T. Ohira, Y. Higo, N. Nakai, K. Imaizumi, A. Ogura, N. Nishimoto, Y. Adachi, Y. Ohira
  • 雑誌名: Cells Tissues Organs 191 ページ: 248-259
  • 査読あり
• [雑誌論文] Role(s) of gravitational loading during developing period on the growth of rat soleus muscle fibers (2010)
  • 著者名/発表者名: Kawano F, K. Goto, X. D. Wang, M. Terada, T. Ohira, N. Nakai, T. Yoshioka, Y. Ohira
  • 雑誌名: J Appl Physiol 108 ページ: 676-685
  • 査読あり
• [雑誌論文] Myonucleus-related properties in soleus muscle fibers of mdx mice (2010)
  • 著者名/発表者名: Terada, et al.
  • 雑誌名: Cells Tissues Organs 191 ページ: 248-259
  • 査読あり
• [雑誌論文] Possible Utilization of Gerbils for Spaceflight Experiment (2009)
  • 著者名/発表者名: Ohira, Y., Y. Nakajima, N. Nakai, F. Kawano, M. Terada, T. Ohira, K. Goto, S. Nagaoka, M. Yamasaki, M., Ishihara, A. and Oishi, Y
  • 雑誌名: Space Utiliz. Res 巻: 25 ページ: 135-136
  • NAID: 120006830538
• [雑誌論文] Effects of hindlimb unloading at early postnatal growth on cell body size in spinal motoneurons innervating soleus muscle of rats (2009)
  • 著者名/発表者名: Nagatomo, F., A. Ishihara, and Y. Ohira
  • 雑誌名: Int' l. J. Develop. Neurosci 巻: 27 ページ: 21-26
• [雑誌論文] Neural and/ or mechanical responses of adductor longus muscle to exposure to microgravity in Wistar Hannover rats (2009)
  • 著者名/発表者名: Ohira, T., M. Terada, F. Kawano, N. Nakai, K. Ohira, T. Ochiai, J. Gyotoku, A. Ogura, and Y. Ohira
  • 雑誌名: Jpn. J. Aerosp. Environ. Med 巻: 46(2) ページ: 21-28
  • NAID: 10026940765
• [雑誌論文] Gravitational unloading inhibits the regenerative potential of atrophied soleus muscle in mice (2009)
  • 著者名/発表者名: Matsuba, Y., K. Goto, S. Morioka, T. Naito, T. Akema, N. Hashimoto, T. Sugiura, Y. Ohira, M. Beppu, and T. Yoshioka
  • 雑誌名: Acta Physiol 巻: 196 ページ: 329-339
• [雑誌論文] Administration of granulocyte colony-stimulating factor facilitates the regenerative process of injured mice skeletal muscle via the activation of Akt/ GSK3αβsignals (2009)
  • 著者名/発表者名: Naito, T., K. Goto, S. Morioka, Y. Matuba, T. Akema, T. Sugiura, Y. Ohira, M. Beppu, and T. Yoshioka
  • 雑誌名: Europ. J. Appl. Physiol 巻: 105 ページ: 643-651
• [雑誌論文] Heat stress increases myonuclear number and fiber size via satellite cell activation in rat regenerating soleus fibers (2009)
  • 著者名/発表者名: Oishi, Y., M. Hayashida, S. Tsukiashi, K. Taniguchi, K. Kami, R. R. Roy, and Y. Ohira
  • 雑誌名: J. Appl. Physiol 巻: 107 ページ: 1612-1621
• [雑誌論文] Heat stress increases myonuclear number and fiber size via satellite cell activation in rat regenerating soleus fibers (2009)
  • 著者名/発表者名: Oishi, Y., M. Hayashida, S. Tsukiashi, K. Taniguchi, K. Kami, R. R. Roy, Y. Ohira
  • 雑誌名: J.Appl.Physiol. 107 ページ: 1612-1621
  • 査読あり
• [雑誌論文] Heat stress increases myonuclear number and fiber size via satellite cell activation in rat regenerating soleus fibers (2009)
  • 著者名/発表者名: Oishi, et al.
  • 雑誌名: J. Appl. Physiol. 107 ページ: 1612-1621
  • 査読あり
• [雑誌論文] Gravitational unloading inhibits the regenerative potential of atrophied soleus muscle in mice (2009)
  • 著者名/発表者名: Matsuba, et al.
  • 雑誌名: Acta Physiol. 196 ページ: 329-339
  • 査読あり
• [雑誌論文] Investigation of the mechanism responsible for muscle atrophy and countermeasures in microgravity environment : Role(s) of mechanical load and/ or satellite cells (2008)
  • 著者名/発表者名: Ohira, Y., X. D. Wang, M. Terada, F. Kawano, Y. Matsuoka, Y. Higo, T. Ohira, A. Kojima, K. Goto, and T. Yoshioka
  • 雑誌名: Proceedings of the 1st International Space Medicine Symposium 2007 in Sapporo ページ: 91-96
• [雑誌論文] Cellular adaptations in soleus muscle during recovery after hindlimb unloading (2008)
  • 著者名/発表者名: Oishi, Y., T. Ogata, K. Yamamoto, M. Terada, T. Ohira, Y. Ohira, K. Taniguchi, and R. R. Roy
  • 雑誌名: Acta Physiol 巻: 192 ページ: 381-395
• [雑誌論文] Effects of loading or unloading on the regenerative potential of injured skeletal muscle in mice (2008)
  • 著者名/発表者名: Goto, K., Y. Matsuba, Y. Ohno, T. Sugiura, N. Hashimoto, Y. Ohira, and T. Yoshioka
  • 雑誌名: J. Gravit. Physiol 巻: 15 ページ: 83-84
• [雑誌論文] Garavitational loading stimulates adhesion of satellite cells and myonuclear accretion during fiber growth in rat soleus muscle (2008)
  • 著者名/発表者名: Kawano, F., X. D. Wang, N. Nakai, Y. Higo, M. Terada, T. Ohira, I. Nonaka, and Y. Ohira
  • 雑誌名: J. Gravit. Physiol 巻: 15 ページ: 85-86
• [雑誌論文] Role(s) of gravitational loading on the growth-related transformation of fiber phenotype in rat soleus (2008)
  • 著者名/発表者名: Ohira, Y., F. Kawano, K. Goto, M. Terada, T. Ohira, N. Nakai, Y. Higo, and T. Yoshioka
  • 雑誌名: J. Gravit. Physiol 巻: 15 ページ: 93-94
• [雑誌論文] Responses of electromyogram activity in adductor longus muscle of rats to the altered gravity levels (2008)
  • 著者名/発表者名: Ohira, T., X. D. Wang, M. Terada, F. Kawano, Y. Higo, N. Nakai, T. Ochiai, J. Gyotoku, N. Nishimoto, A. Ogura, and Y. Ohira
  • 雑誌名: J. Gravit. Physiol 巻: 15 ページ: 95-96
• [雑誌論文] Effects of mechanical overloading on the properties of soleus muscle fibers, with or without damage, in mdx and wild type mice (2008)
  • 著者名/発表者名: Terada, M., F. Kawano, T. Ohira, Y. Oke, N. Nakai, and Y. Ohira
  • 雑誌名: J. Gravit. Physiol 巻: 15 ページ: 97-98
• [雑誌論文] Effects of peroxisome proliferator-activated receptor.(PPAR.) agonists on leucine-induced phosphorylation of translational targets in C2C12 cells (2008)
  • 著者名/発表者名: Nakai, N., F. Kawano, M. Terada, Y. Oke, T. Ohira, and Y. Ohira
  • 雑誌名: Biochim. Biophys. Acta 巻: 1780 ページ: 1101-1105
• [雑誌論文] Essential role of satellite cells in the growth of rat soleus muscle fibers (2008)
  • 著者名/発表者名: Kawano, F., Y. Takeno, N. Nakai, Y. Higo, M. Terada, T. Ohira, I. Nonaka, and Y. Ohira
  • 雑誌名: Am. J. Physiol. Cell Physiol 巻: 295
• [雑誌論文] Gene expression levels of heat shock proteins in soleus and plantaris muscles of rats after hindlimb suspension or spaceflight (2008)
  • 著者名/発表者名: Ishihara, A., H. Fujino, F. Nagatomo, I. Takeda, and Y. Ohira
  • 雑誌名: J. Physiol. Sci 巻: 58 ページ: 413-417
• [雑誌論文] Functional overloading facilitates the regeneration of injured soleus muscles in mice (2008)
  • 著者名/発表者名: Morioka, S., K. Goto, A. Kojima, T. Naito, Y. Matsuba, T. Akema, H. Fujiya, T. Sugiura, Y. Ohira, M. Beppu, H. Aoki, and T. Yoshioka
  • 雑誌名: J. Physiol. Sci 巻: 58 ページ: 397-404
• [雑誌論文] Effects of peroxisome proliferator-activated receptor α (PPARα) agonists on leucine-induced phosphorylation of translational targets in C2C12 cells (2008)
  • 著者名/発表者名: Nakai, N., F. Kawano, M. Terada, Y. Oke, T. Ohira, Y. Ohira
  • 雑誌名: Biochim. Biophys. Acta 1780 ページ: 1101-1105
  • 査読あり
• [雑誌論文] Essential role of satellite cells in the growth of rat soleus muscle fibers (2008)
  • 著者名/発表者名: Kawano, F., Y. Takeno, N. Nakai, Y. Higo, M. Terada, T. Ohira, I. Nonaka, Y. Ohira
  • 雑誌名: Am.J.Physiol. Cell Physiol. 295
  • 査読あり
• [雑誌論文] Heat-stress facilitates the regeneration of injured skeletal muscle in rats (2007)
  • 著者名/発表者名: Kojima, A., K. Goto, S. Morioka, T. Naito, T. Akema, H. Fujiya, T. Sugiura, Y. Ohira, M. Beppu, H. Aoki, and T. Yoshioka
  • 雑誌名: J. Orthopaed. Sci 巻: 12 ページ: 74-82
• [雑誌論文] Transcription regulation of gene expression in rat brown adipose tissue in response to unloading or 2G loading during growing period (2007)
  • 著者名/発表者名: Watanabe, S., Y. Hitomi, F. Kawano, Y. Ohira, T. Kizaki, N. Nakano, T. Sakurai, T. Izawa, K. Suzuki, M. Sudoh, R. R. Roy, and H. Ohno
  • 雑誌名: Acta Astronautica 巻: 60 ページ: 889-898
• [雑誌論文] Geranylgeranylaceton induces heat shock protein 72 in skeletal muscle cells (2007)
  • 著者名/発表者名: Goto, K., A. Kojima, S. Morioka, T. Naito, T. Akema, Y. Matsuba, H. Fujiya, T. Sugiura, Y. Ohira, and T. Yoshioka
  • 雑誌名: Biochem. Biophys. Res. Commun 巻: 358 ページ: 331-335
• [雑誌論文] Skeletal muscle hypertrophy induced by low-intensity exercise with heat-stress in healthy human subjects (2007)
  • 著者名/発表者名: Goto, K., H. Oda, S. Morioka, T. Naito, T. Akema, H. Kato, H. Fujiya, Y. Nakajima, T. Sugiura, Y. Ohira, and T. Yoshioka
  • 雑誌名: Jpn. J. Aerosp. Environ. Med 巻: 44 ページ: 13-18
• [雑誌論文] Effects of mechanical and/ or neural stimuli on the properties of soleus muscle fibers in mdx mice (2007)
  • 著者名/発表者名: Lan, Y. B., M. Terada, Y. Higo, F. Kawano, Y. Matsuoka, X. D. Wang, N. Nakai, and Y. Ohira
  • 雑誌名: Jpn. J. Aerosp. Environ. Med 巻: 44 ページ: 19-29
  • NAID: 10019856657
• [雑誌論文] Role(s) of nucleoli and phosphorylation of ribosomal protein S6 and/ or HSP27 in the regulation of muscle mass (2007)
  • 著者名/発表者名: Kawano, F., Y. Matsuoka, Y. Oke, Y. Higo, M. Terada, X. D. Wang, N. Nakai, H. Fukuda, S. Imajoh-Ohmi, and Y. Ohira
  • 雑誌名: Am. J. Physiol. Cell Physiol 巻: 293
• [雑誌論文] Effects of functional overloading on the regenerative potential of injured skeletal muscles in mice (2007)
  • 著者名/発表者名: Goto, K., S. Morioka, T. Naito, T. Akema, Y. Matsuba, T. Sugiura, Y. Ohira, and T. Yoshioka
  • 雑誌名: J. Gravit. Physiol 巻: 14 ページ: 101-102
• [雑誌論文] Cell size and oxidative enzyme activity of rat biceps brachii and triceps brachii muscles (2007)
  • 著者名/発表者名: Matsumoto, A., F. Nagatomo, A. Mori, Y. Ohira, and A. Ishihara
  • 雑誌名: J. Physiol. Sci 巻: 57 ページ: 311-316
• [雑誌論文] Responses of vastus lateralis muscle fibers to cycling training with different loading parameters in human (2007)
  • 著者名/発表者名: Terada, M., E. Lyubaeva, T. Ohira, A. Netreba, F. Kawano, H. Okabe, T. Aoyama, K. Imaizumi, O. Vinogradova, and Y. Ohira
  • 雑誌名: Jpn. J. Aerospace Environ. Med 巻: 44 ページ: 59-64
• [雑誌論文] Effects of hyperbaric exposure with high oxygen concentration on the physical activity of developing rats (2007)
  • 著者名/発表者名: Matsumoto, A., T. Okiura, F. Morimatsu, Y. Ohira, and A. Ishihara
  • 雑誌名: Dev. Neurosci 巻: 29 ページ: 452-459
• [雑誌論文] Role(s) of nucleoli, phosphorylation of ribosomal protein S6 and/or HSP27 in the regulation of muscle mass. (2007)
  • 著者名/発表者名: Kawano, F, Y. Matsuoka, Y. Oke, Y. Higo, M. Terada, X.D. Wang, N. Nakai, H. Fukuda, S. Imajo-Ohmi, and Y. Ohira.
  • 雑誌名: Am. J. Physiol. Cell Physiol. 293
  • 査読あり
• [雑誌論文] Effects of mechanical and neural stimuli on the properties of soleus muscle fibers in mdx mice. (2007)
  • 著者名/発表者名: Lan, Y.B., M. Terada, Y. Higo, F. Kawano, Y. Matsuoka, X.D. Wang, N. Nakai, and Y. Ohira.
  • 雑誌名: Jpn. J. Aerosp. Environ. Med. 44 ページ: 19-29
  • 査読あり
• [雑誌論文] Responses of vastus lateralis muscle fibers to cycling training with different loading parameters in human. (2007)
  • 著者名/発表者名: Terada, M., E. Lyubaeva, T. Ohira, A. Netreba, F. Kawano, H. Okabe, T. Aoyama, K. Imaizumi, O. Vinogradova, and Y. Ohira.
  • 雑誌名: Jpn. J. Aerosp. Environ. Med. 44 ページ: 59-64
  • 査読あり
• [雑誌論文] 宇宙環境暴露および老化による骨格筋の萎縮 (2007)
  • 著者名/発表者名: 宇宙環境暴露および老化による骨格筋の萎縮
  • 雑誌名: 宇宙航空環境医学 44 ページ: 49-58
  • 査読あり
• [雑誌論文] Investigation of the mechanism responsible for muscle atrophy and countermeasures in microgravity environment: Role(s) of mechanical load and/or satellite cells. (2007)
  • 著者名/発表者名: Ohira, Y., X.D. Wang, F. Kawano, M. Terada, Y. Matsuoka, Y. Higo, T. Ohira, A. Kojima, K. Goto, and T. Yoshioka.
  • 雑誌名: Proceedings of the 1st International Space Medicine Symposium 2007 in Sapporo ページ: 91-96
  • 査読あり
• [雑誌論文] Evaluation of gene, protein and neurotrophin expression in the brain of mice exposed to space environment for 91 days
  • 著者名/発表者名: Santucci, D., F. Kawano, T. Ohira, M. Terada, N. Nakai, N. Francia, E. Alleva, L. Aloe, T. Ochiai, R. Cancedda, K. Goto, and Y. Ohira
  • 雑誌名: PLoS ONE 巻: (in press)
• [雑誌論文] Effects of inhibited antigravity muscle activity on the expression of hippocampal proteins in growing rats
  • 著者名/発表者名: Oke, Y., F. Kawano, S. Nomura, T. Ohira, R. Fujita, M. Terada, T. Shibaguchi, N. Nakai, and Y. Ohira
  • 雑誌名: Jpn. J. Aerosp. Envion. Med 巻: (in press)
• [雑誌論文] Responses of HSC70 expression in diencephalon to iron deficiency anemia in rats
  • 著者名/発表者名: Kawano, F., Y. Oke, S. Nomura, R. Fujita, T. Ohira, N. Nakai, and Y. Ohira
  • 雑誌名: J. Physiol. Sci 巻: (in press)
  • NAID: 10030350860
• [雑誌論文] Effects of mechanical over-loading on the properties of soleus muscle fibers, with or without damage, in wild type and mdx mice
  • 著者名/発表者名: Terada, M., F. Kawano, T. Ohira, N. Nakai, N. Nishimoto, and Y. Ohira
  • 雑誌名: PLoS ONE 巻: (in press)
• [雑誌論文] Neuromuscular responses to spaceflight
  • 著者名/発表者名: Ohira, Y., F. Kawano, T. Ohira, T. Ohira, H. Okabe, H. Naito, K. Goto, and A. Ishihara
  • 雑誌名: J. Gravit. Physiol.(Review) 巻: (in press)
• [雑誌論文] Regulation of soleus muscle properties by mechanical stress and/ or neural acrivity
  • 著者名/発表者名: Kawano, F., N. Nakai, and Y. Ohira
  • 雑誌名: J. Phys. Fit. Sports Med.(Review) 巻: (in press)
• [雑誌論文] Some aspects of heat stress on the plasticity of skeletal muscle cells
  • 著者名/発表者名: Goto, K., Y. Ohno, A. Goto, A. Ikuta, M. Suzuki, T. Ohira, N. Tsuchiya, S. Nishizawa, T. Koya, T. Egawa, T. Sugiura, Y. Ohira, and T. Yoshioka, T
  • 雑誌名: J. Phys. Fit. Sports Med.(Review) 巻: (in press)
• [雑誌論文] Control of muscle protein synthesis in response to exercise and amino acids
  • 著者名/発表者名: Nakai, N., F. Kawano, and Y. Ohira
  • 雑誌名: J. Phys. Fit. Sports Med.(Review) 巻: (in press)
  • NAID: 10031158957
• [雑誌論文] Effects of mechanical over-loading on the properties of soleus muscle fibers, with or without damage, in wild type and mdx mice
  • 著者名/発表者名: Terada, M., F.Kawano, T.Ohira, N.Nakai, N.Nishimoto, Y.Ohira
  • 雑誌名: PLoS ONE 巻: (In press)
  • 査読あり
• [雑誌論文] The impact of long-term exposure to space environment on adult mammalian organisms: a study on mouse thyroid and testis
  • 著者名/発表者名: Masini, M.A., E.Albi, C.Barmo, T.Bonfiglio, L.Bruni, L.Canesi, S.Cataldi, F.Curcio, M.D'Amora, I.Ferri, K.Goto, F.Kawano, R.Lazzarini, E.Loreti, N.Nakai, T.Ohira, Y.Ohira, S.Palmero, P.Prato, F.Ricci, L.Scarabelli, T.Shibaguchi, R.Spelat, F.StroUo, F.S.Ambesi-Impiombato
  • 雑誌名: PLoS ONE 巻: (In press)
  • 査読あり
• [雑誌論文] Regulation of soleus muscle properties by mechanical stress and/or neural acrivity
  • 著者名/発表者名: Kawano, E., N.Nakai, Y.Ohira
  • 雑誌名: J.Phys.Fit.Sports Med. 巻: (In press)
  • 査読あり
• [雑誌論文] Effects of inhibited antigravity muscle activity on the expression of hippocampal proteins in growing rats
  • 著者名/発表者名: Oke, Y., F.Kawano, S.Nomura, T.Ohira, R.Fujita, M.Terada, T.Shibaguchi, N.Nakai, Y.Ohira
  • 雑誌名: Jpn.J.Aerosp.Envion.Med. 巻: (In press)
  • 査読あり
• [雑誌論文] Responses of HSC70 expression in diencephalon to iron deficiency anemia in rats
  • 著者名/発表者名: Kawano, F., Y.Oke, S.Nomura, R.Fujita, T.Ohira, N.Nakai, Y.Ohira
  • 雑誌名: J.Physiol.Sci. 巻: (In press)
  • NAID: 10030350860
  • 査読あり
• [雑誌論文] Neuromuscular responses to spaceflight
  • 著者名/発表者名: Ohira, Y., F.Kawano, T.Ohira, T.Ohira, H.Okabe, H.Naito, K.Goto, A.Ishihara
  • 雑誌名: J.Gravit.Physiol. 巻: (In press)
  • 査読あり
• [雑誌論文] Effects of creatine and its analog, β-guanidinopropionic acid, on the differentiation and nucleoli in myoblasts
  • 著者名/発表者名: Ohira, Y., et al
  • 雑誌名: Biosci.Biotechnol.Biochem. 巻: (In press)
  • 査読あり
• [雑誌論文] Region-specific responses of adductor longus muscle to gravitational load-dependent activity in Wistar Hannover rats
  • 著者名/発表者名: Ohira, T., et al
  • 雑誌名: PLoS ONE 巻: (In press)
  • 査読あり
• [学会発表] Expectation for suborbital flight as life science experiment opportunity (2012)
  • 著者名/発表者名: Ochiai, T., H.Murase, Y.Ohira
  • 学会等名: Next-generation Suborbital Researchers Conference
  • 発表場所: Palo Alto, CA, U.S.A.
  • 年月日: 2012-02-27
• [学会発表] Recording of neuromuscular activities of rats in a real microgravity environment using telemetry system (2012)
  • 著者名/発表者名: Kawano, R, T.Ohira, T.Ochiai, Y.Ohira
  • 学会等名: Next-generation Suborbital Researchers Conference
  • 発表場所: Palo Alto, CA, U.S.A.
  • 年月日: 2012-02-26
• [学会発表] How does carp fish tilt the body in response to light under microgravity environment? (2012)
  • 著者名/発表者名: Ohira, T., T.Shibaguchi, T.Ohira, M.Yamada, F.Kawano, A.Takabayashi, T.Ochiai, Y.Ohira
  • 学会等名: Next-generation Suborbital Researchers Conference
  • 発表場所: Palo Alto, CA, U.S.A.
  • 年月日: 2012-02-26
• [学会発表] The MDS mission : adaptataion of skeletal muscle to long-term microgravity (2011)
  • 著者名/発表者名: Desaphy, J -F., D.Sandona, G M.Camerino, E.Bianchini, S.Ciciliot, D.Danieli-Betto, G.Dobrowolny, S.Furlan, E.Germinario, K.Goto, M.Gutsmann, F.Kawano, N.Nakai, T.Ohira, A.Picard, M.Salanova, G.Schiffl, A.Musaro, D.Blottner, Y.Ohira, R.Betto, S.Schiaffino, D.Conte
  • 学会等名: 2011 ASGSB/ISGP Joint Conference, American Society for Gravitational and Space Biology (ASGSB) the 27^<th> Annual Meeting/International Society for Gravitational Physiology (ISGP) the 32^<nd> Annual Meeting
  • 発表場所: San Jose, California, U.S.A.
  • 年月日: 2011-11-06
• [学会発表] Adaptation of mouse brain, testis & epididymis, upper spinal cord, and hairroots to microgravity (2011)
  • 著者名/発表者名: Ohira, Y., K.Goto, A.Ishihara, D.Santucci, M.A.Masini, T.Ochiai, R.Cancedda
  • 学会等名: 2011 ASGSB/ISGP Joint Conference, American Society for Gravitational and Space Biology (ASGSB) the 27^<th> Annual Meeting/International Society for Gravitational Physiology (ISGP) the 32^<nd> Annual Meeting
  • 発表場所: San Jose, California, U.S.A.(招待講演)
  • 年月日: 2011-11-06
• [学会発表] Effects of long term space flight on erythrocytes and oxidative stress of mice (2011)
  • 著者名/発表者名: Rizzo, A.M., G.Montorfano, P.Corsetto, S.Tavella, Y.Ohira, R.Cancedda, B.Berra
  • 学会等名: 2011 ASGSB/ISGP Joint Conference, American Society for Gravitational and Space Biology (ASGSB) the 27^<th> Annual Meeting/International Society for Gravitational Physiology (ISGP) the 32^<nd> Annual Meeting
  • 発表場所: San Jose, California, U.S.A.
  • 年月日: 2011-11-06
• [学会発表] Effects of 3-month-exposure to microgravity on microRNA expressions in mouse skeletal muscles (2011)
  • 著者名/発表者名: Goto, K., Y.Ohno, F.Kawano, T.Ohira, R.Betto, S.Schiaffino, Y.Ohira
  • 学会等名: 2011 ASGSB/ISGP Joint Conference, American Society for Gravitational and Space Biology (ASGSB) the 27^<th> Annual Meeting/International Society for Gravitational Physiology (ISGP) the 32^<nd> Annual Meeting
  • 発表場所: San Jose, California, U.S.A.
  • 年月日: 2011-11-04
• [学会発表] Up-regulation of heat shock proteins in skeletal muscle of heat shock transcription factor 1-null mice (2011)
  • 著者名/発表者名: Ohno, Y., K.Goto, T.Sugiura, Y.Ohira, T.Yoshioka
  • 学会等名: 2011 ASGSB/ISGP Joint Conference, American Society for Gravitational and Space Biology (ASGSB) the 27^<th> Annual Meeting/International Society for Gravitational Physiology (ISGP) the 32^<nd> Annual Meeting
  • 発表場所: San Jose, California, U.S.A.
  • 年月日: 2011-11-04
• [学会発表] Limiting factor(s) during bicycle ergometer exercise in human subjects with altered blood distribution (2011)
  • 著者名/発表者名: Okabe, H., T.Kawabata, T.Ohira, F.Kawano, H.Naito, Y.Ohira
  • 学会等名: 2011 ASGSB/ISGP Joint Conference, American Society for Gravitational and Space Biology (ASGSB) the 27^<th> Annual Meeting/International Society for Gravitational Physiology (ISGP) the 32^<nd> Annual Meeting
  • 発表場所: San Jose, California, U.S.A.
  • 年月日: 2011-11-04
• [学会発表] The genetic analyses on body hair roots of space-flown mice as complement of human research (2011)
  • 著者名/発表者名: Terada, M., R.Nakano, H.J.Majima, T.Yamazaki, A.Higashibata, N.Ishioka, Y.Ohira
  • 学会等名: 2011 ASGSB/ISGP Joint Conference, American Society for Gravitational and Space Biology (ASGSB) the 27^<th> Annual Meeting/International Society for Gravitational Physiology (ISGP) the 32^<nd> Annual Meeting
  • 発表場所: San Jose, California, U.S.A.
  • 年月日: 2011-11-04
• [学会発表] Micro-gravity experiment using meriones unguiculatus (Mongolian Gerbil) (2011)
  • 著者名/発表者名: Ochiai, T., H.Murase, A.Homma, V.R.Edgerton, Y.Ohira
  • 学会等名: 2011 ASGSB/ISGP Joint Conference, American Society for Gravitational and Space Biology (ASGSB) the 27^<th> Annual Meeting/International Society for Gravitational Physiology (ISGP) the 32^<nd> Annual Meeting
  • 発表場所: San Jose, California, U.S.A.
  • 年月日: 2011-11-04
• [学会発表] Role of skeletal muscles and/or fins during gravity-and/or light-dependent body tilting in carp fishes (2011)
  • 著者名/発表者名: Ohira, T., T.Shibaguchi, T.Ohira, M.Yamada, F.Kawano, A.Takabayashi, Y.Ohira
  • 学会等名: 2011 ASGSB/ISGP Joint Conference, American Society for Gravitational and Space Biology (ASGSB) the 27^<th> Annual Meeting/International Society for Gravitational Physiology (ISGP)the 32^<nd> Annual Meeting
  • 発表場所: San Jose, California, U.S.A.
  • 年月日: 2011-11-03
• [学会発表] Long-term exposure to real and simulated microgravity depresses the number of epididymal sperm in mice (2011)
  • 著者名/発表者名: Shibaguchi, T., T.Ohira, F.Kawano, N.Nakai, K.Goto, T.Ochiai, Y.Ohira
  • 学会等名: 2011 ASGSB/ISGP Joint Conference, American Society for Gravitational and Space Biology (ASGSB) the 27^<th> Annual Meeting/International Society for Gravitational Physiology (ISGP) the 32^<nd> Annual Meeting
  • 発表場所: San Jose, California, U.S.A.
  • 年月日: 2011-11-03
• [学会発表] Adiponectin expression of skeletal muscle in response to unloading and reloading in mice (2011)
  • 著者名/発表者名: Goto, A., Y.Ohno, A.Ikuta, K.Goto, T.Sugiura, Y.Ohira, T.Yoshioka
  • 学会等名: 2011 ASGSB/ISGP Joint Conference, American Society for Gravitational and Space Biology (ASGSB) the 27^<th> Annual Meeting/International Society for Gravitational Physiology (ISGP) the 32^<nd> Annual Meeting
  • 発表場所: San Jose, California, U.S.A.
  • 年月日: 2011-11-03
• [学会発表] Effects of application of heat-stress for prevention of unloading-related atrophy and stimulation of recovery of skeletal muscle (2011)
  • 著者名/発表者名: Yoshioka, T., K.Goto, T.Sugiura, Y.Ohira
  • 学会等名: Space Forum-2011, Dedicated to the 50-th Anniversary of the First Human space Flight by Yury Gagarin
  • 発表場所: Moscow, Russia
  • 年月日: 2011-10-07
• [学会発表] Body tilting in response to gravity and/or dorsal light response in carp fishes : roles of skeletal muscles and/or fins (2011)
  • 著者名/発表者名: Ohira, Takashi, T.Shibaguchi, T.Ohira, M.Yamada, F.Kawano, A.Takabayashi, Y.Ohira
  • 学会等名: The 7th Congress of the Federations of Asian and Oceanian Physiological Societies (FAOPS)
  • 発表場所: Taipei, Taiwan
  • 年月日: 2011-09-13
• [学会発表] Effects of 3-month spaceflight on the characteristics of neck muscle in mice (2011)
  • 著者名/発表者名: Ohira, Tomotaka, T.Ohira, F.Kawano, T.Shibaguchi, R.Fujita, N.Nakai, K.Goto, H.Okabe, F.Ogita, T.Ochihai, R.Cancedda, Y.Ohira
  • 学会等名: The 7th Congress of the Federations of Asian and Oceanian Physiological Societies (FAOPS)
  • 発表場所: Taipei, Taiwan
  • 年月日: 2011-09-13
• [学会発表] Exercise prescription for stimulated mobilization of soleus muscle in human (2011)
  • 著者名/発表者名: Okabe, H., T.Ohira, F.Kawano, Y.Oke, R.Fujita, T.Ohira, N.Nakai, Y.Ohira
  • 学会等名: The 7th Congress of the Federations of Asian and Oceanian Physiological Societies (FAOPS)
  • 発表場所: Taipei, Taiwan
  • 年月日: 2011-09-13
• [学会発表] Effects of 3-month exposure to real microgravity environment on epididymal sperm number in mice (2011)
  • 著者名/発表者名: Shibaguchi, T., T.Ohira, R.Fujita, T.Ohira, F.Kawano, N.Nakai, K.Goto, H.Okabe, T.Ochiai, R.Cancedda, Y.Ohira
  • 学会等名: The 7th Congress of the Federations of Asian and Oceanian Physiological Societies (FAOPS)
  • 発表場所: Taipei, Taiwan
  • 年月日: 2011-09-13
• [学会発表] Expression of micro-RNA in mouse skeletal muscle after unloading and reloading (2011)
  • 著者名/発表者名: Goto, K., Y.Ohno, A.Goto, A.Ikuta, K.Yasuhara, T.Sugiura, Y.Ohira, T.Yoshioka
  • 学会等名: The 7th Congress of the Federations of Asian and Oceanian Physiological Societies (FAOPS)
  • 発表場所: Taipei, Taiwan
  • 年月日: 2011-09-12
• [学会発表] Effects of IL-6 receptor inhibition and/or heat treatment on the regeneration of injured mouse skeletal muscle (2010)
  • 著者名/発表者名: Fujita R., et al
  • 学会等名: Experimetal Biology meeting 2010
  • 発表場所: Anaheim, Calif., U.S.A.
  • 年月日: 2010-04-25
• [学会発表] 温熱刺激による損傷骨格筋の再生促進には白血球または骨髄細胞が関与している (2009)
  • 著者名/発表者名: 大平充宣, 上勝也, 後藤勝正
  • 学会等名: 第55回日本宇宙航空環境医学会大会・シンポジ?ウム
  • 発表場所: 岐阜市
  • 年月日: 2009-11-14
• [学会発表] 神経・筋の特性は筋が決める?!(特別講演) (2009)
  • 著者名/発表者名: 大平充宣
  • 学会等名: 日本体力医学会・第13回東海地方会
  • 発表場所: 名古屋大学
  • 年月日: 2009-03-15
• [学会発表] How can we promote the regeneration of skeletal muscles? Systemic and cellular mechanisms in physiology of motor system (2009)
  • 著者名/発表者名: Ohira, Y., K. Goto, T. Ohira, H. Okabe
  • 学会等名: 5th Russian National School with Int'l. Participation on Muscle and Exercise Physiology, Russian Academy of Sciences
  • 発表場所: Moscow, Russia
  • 年月日: 2009-02-03
• [学会発表] Effects of macrophage on unloading/reloading-related regulation of muscle fiber size in op/op mice (2009)
  • 著者名/発表者名: Ohira, T., X. D. Wang, F. Kawano, M. Terada, H. Yamamoto, T. Ito, N. Nakai, K. Goto, Y. Ohira
  • 学会等名: Experimental Biology
  • 発表場所: New Orleans, Louisiana, U.S.A.
• [学会発表] Mechanical stress に応じた衛星細胞の特性が関与した骨格筋の可塑性。シンポジウム "メカニカルストレスに対する筋・骨格系の応答の分子機構" (2008)
  • 著者名/発表者名: 大平充宣, 後藤勝正
  • 学会等名: 第31回日本分子生物学会年会・第81回日本生化学会大会・合同大会、神戸ポートアイランド
  • 年月日: 2008-12-12
• [学会発表] Neuromuscular adaptation to use and/or disuse : Role of satellite cells (2008)
  • 著者名/発表者名: Ohira, Y.
  • 学会等名: 6th International Conference of Sport Science (Special lecture, p. 67)
  • 発表場所: Hochiminh City, Vietnam
  • 年月日: 2008-08-29
• [学会発表] Geranylgeranylaceton increases protein content and heat stress protein 72 expression in skeletal muscle cells. (2007)
  • 著者名/発表者名: Goto, K., S. Morioka, T. Naito, A. Kojima, T. Akema, H. Fujiya, T. Sugiura, Y. Ohira, and T. Yoshioka.
  • 学会等名: 23rd Annual Meet. of Am. Soc. Gravit. Space Biol.
  • 発表場所: Moffett Field, Ca., U.S.A.
  • 年月日: 2007-10-27
• [学会発表] Responses of protein expression to cardiotoxin-induced muscle injury. (2007)
  • 著者名/発表者名: Kawano, F., M. Terada, N. Nakai, T. Ohira, Y. Higo, N. Nishimoto, and Y. Ohira.
  • 学会等名: 23rd Annual Meet. of Am. Soc. Gravit. Space Biol.
  • 発表場所: Moffett Field, Ca., U.S.A.
  • 年月日: 2007-10-27
• [学会発表] Effects of inhibited neural and/or mechanical stimuli on the water content and dry weight in rat hindlimb muscles. (2007)
  • 著者名/発表者名: Wang, X.D., M. Danda, M. Terada, F. Kawano, T. Ohira, Y. Higo, Y. Nakajima, N. Nakai, K. Goto, and Y. Ohira.
  • 学会等名: 23rd Annual Meet. of Am. Soc. Gravit. Space Biol.
  • 発表場所: Moffett Field, Ca., U.S.A.
  • 年月日: 2007-10-27
• [学会発表] Are the responses of adductor longus muscle to gravitational unloading in Wistar Hannover rats region-specific? (2007)
  • 著者名/発表者名: Ohira, T., X.D. Wang, M. Terada, F. Kawano, Y. Higo, N. Nakai, T. Ochiai, J. Gyotoku, N. Nishimoto, and Y. Ohira
  • 学会等名: 23rd Annual Meet. of Am. Soc. Gravit. Space Biol.
  • 発表場所: Moffett Field, Ca., U.S.A.
  • 年月日: 2007-10-26
• [学会発表] Responses of back muscle fibers in Sprague-Dawley rats to spaceflight. (2007)
  • 著者名/発表者名: Terada, M., F. Kawano, H. Kume, T. Ohira, Y. Higo, Y. Nakajima, X.D. Wang, N. Nakai, W.E. Hinds, and Y. Ohira
  • 学会等名: 23rd Annual Meet. of Am. Soc. Gravit. Space Biol.
  • 発表場所: Moffett Field, Ca., U.S.A.
  • 年月日: 2007-10-26
• [学会発表] Responses of body composition and hematological and muscular properties of meriones unguiculatus to gravitational unloading. (2007)
  • 著者名/発表者名: Nakajima, Y., M. Terada, F. Kawano, H. Sumi, Y. Shimizu, T. Ohira, Y. Higo, X.D. Wang, N. Nakai, and Y. Ohira
  • 学会等名: 23rd Annual Meet. of Am. Soc. Gravit. Space Biol.
  • 発表場所: Moffett Field, Ca., U.S.A.
  • 年月日: 2007-10-26
• [学会発表] Peroxisome proliferators-activated receptor α (PPARα) agonist, WY-14, 643, increased leucine-induced activation of translation initiation in C2C12 cells. (2007)
  • 著者名/発表者名: Nakai, N., F. Kawano, M. Terada, and Y. Ohira
  • 学会等名: 12th International Congress of World Muscle Society
  • 発表場所: Messina, Sicily, Italy
  • 年月日: 2007-10-19
• [学会発表] The characters of soleus muscle fibers of mdx mice with different distribution of myonuclei. (2007)
  • 著者名/発表者名: Terada, M., F. Kawano, Y. Higo, T. Ohira, X. Wang, N. Nakai, and Y. Ohira
  • 学会等名: 12th International Congress of World Muscle Society
  • 発表場所: Messina, Sicily, Italy
  • 年月日: 2007-10-18
• [図書] 運動・加齢に対する骨格筋の適応 (2010)
  • 著者名/発表者名: 上勝也、大平充宣
  • 出版者: The Bone
• [図書] 免疫力を高める運動とは?運動と免疫 (2009)
  • 著者名/発表者名: 上勝也、大平充宣
  • 出版者: ナップ
• [図書] 運動と無重力環境と免疫 (2009)
  • 著者名/発表者名: 大平宇志、西本憲弘、大平充宣
  • 出版者: ナップ
• [図書] The role of branched-chain amino acids in energy metabolism and protein synthesis in skeletal muscle. In" Muscle Cell Physiology" (2009)
  • 著者名/発表者名: Nakai, N. and Y. Ohira
  • 出版者: Ed. by Y. Ohira, Osaka University Press
• [図書] Metabolic modulation of muscle properties : Role(s) of high-energy phosphates. In" Muscle Cell Physiology" (2009)
  • 著者名/発表者名: Ohira, Y
  • 出版者: Ed. by Y. Ohira, Osaka University Press
• [図書] Role of mechanical stress and neural activity in the regulation of antigravity muscle. In" Muscle Cell Physiology" (2009)
  • 著者名/発表者名: Kawano, F., N. Nakai, and Y. Ohira
  • 出版者: Ed. by Y. Ohira, Osaka University Press
• [図書] A hypertrophic stimulus for skeletal muscles. In" Muscle Cell Physiology" (2009)
  • 著者名/発表者名: Goto, K., Y. Ohira, and T. Yoshioka. Heat stress
  • 出版者: Ed. by Y. Ohira, Osaka University Press
• [図書] From intracellular signaling pathways to behavior. In" Muscle Cell Physiology" (2009)
  • 著者名/発表者名: Kami, K. and Y. Ohira. Skeletal muscle regeneration
  • 出版者: Ed. by Y. Ohira, Osaka University Press
• [図書] Neuromuscular Regeneration, Graduate School of Medicine and Frontier Biosciences (2009)
  • 著者名/発表者名: Ohira, Y., Ed.
  • 出版者: Osaka University
• [図書] Muscle Cell Physiology (2009)
  • 著者名/発表者名: Ohira, Y., Ed.
  • 出版者: Osaka University Press
• [図書] Muscle Cell Physiology (2009)
  • 著者名/発表者名: Ohira, Y.(Ed.)
  • 総ページ数: 136
  • 出版者: Osaka University Press
• [図書] 血液。運動療法と運動処方。身体活動・運動支援を効果的に進めるための知識と技術。第2版 (2008)
  • 著者名/発表者名: 大平充宣
  • 出版者: 文光堂
• [図書] 宇宙飛行士の体力。体力とはなにか-運動処方のその前に.長澤純一(編) (2007)
  • 著者名/発表者名: 大平充宣
  • 出版者: ナップ
• [図書] 重力と気圧:宇宙。「環境生理学」、本間研一・彼末一之・編 (2007)
  • 著者名/発表者名: 大平充宣、関口千春、石井正則、石原昭彦
  • 出版者: 北海道大学出版会
• [図書] 宇宙環境への適応とその防止策。「スポーツの科学」 (2007)
  • 著者名/発表者名: 大平充宣
  • 出版者: 財団法人日本学術協力財団
• [図書] かけがえのない水の惑星・地球,人体には水が必須!,水・その不思議な世界:私たちの星を守るために (2007)
  • 著者名/発表者名: 大平充宣
  • 出版者: 高知新聞社
• [備考]
  • URL: http://hw001.gate01.com/kawaco/