| 研究課題/領域番号 |
19F19089
|
|---|
| 研究種目 |
特別研究員奨励費
|
| 配分区分 | 補助金 |
|---|
| 応募区分 | 外国 |
|---|
| 審査区分 |
小区分45020:進化生物学関連
|
|---|
| 研究機関 | 東京大学 |
|---|
研究代表者 |
岩崎 渉 東京大学, 大学院理学系研究科(理学部), 准教授 (50545019)
|
|---|
| 研究分担者 |
CHEN ERIC 東京大学, 大学院理学系研究科, 外国人特別研究員
|
|---|
| 研究期間 (年度) |
2019-04-25 – 2021-03-31
|
| 研究課題ステータス |
完了 (2020年度)
|
| 配分額 *注記 |
2,300千円 (直接経費: 2,300千円)
2020年度: 1,100千円 (直接経費: 1,100千円)
2019年度: 1,200千円 (直接経費: 1,200千円)
|
|---|
| キーワード | ゲノム進化 / バイオインフォマティクス / genome / evolution |
|---|
| 研究開始時の研究の概要 |
In this study, we will test the controversial hypothesis that polyploids are better at adapting to new niches compared to their diploid counterparts and if recent hybrids are more advantageous than diploids and explore if this phenomenon can be explained by genomic data. Specifically, we will use a recent novel design that used to study the evolution of antibiotic resistance, to measure the adaptation speed of these model fungi.
|
| 研究実績の概要 |
In the second year, we successfully conducted experiments with gradients of increasing harshness with two different kinds of stress, such as fungicide and high salt concentration. As expected, each successive zone required a different mechanism for the fungi to cope with the new environment. The speed of adaptation in this variant became a proxy of how fast the fungi can reorient themselves to new stress with each new zone. We also conducted mixing competition assay into additional culture experiments by making the starting colony a 50:50 mixture of hybrid-diploid pair that share closely related subgenomes. Nanopore sequencing was also conducted to retrieve genomic data. The results are being analyzed in depth.
|
| 現在までの達成度 (段落) |
令和2年度が最終年度であるため、記入しない。
|
| 今後の研究の推進方策 |
令和2年度が最終年度であるため、記入しない。
|
