| 研究課題/領域番号 |
20K06612
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| 研究種目 |
基盤研究(C)
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| 配分区分 | 基金 |
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| 応募区分 | 一般 |
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| 審査区分 |
小区分43060:システムゲノム科学関連
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| 研究機関 | 国立遺伝学研究所 |
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研究代表者 |
クリュコフ キリル 国立遺伝学研究所, Biological Networks Laboratory, 特命准教授 (20806202)
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| 研究期間 (年度) |
2020-04-01 – 2023-03-31
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| 研究課題ステータス |
完了 (2022年度)
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| 配分額 *注記 |
4,290千円 (直接経費: 3,300千円、間接経費: 990千円)
2022年度: 910千円 (直接経費: 700千円、間接経費: 210千円)
2021年度: 1,690千円 (直接経費: 1,300千円、間接経費: 390千円)
2020年度: 1,690千円 (直接経費: 1,300千円、間接経費: 390千円)
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| キーワード | Data compression / NAF / GenomeSync / Genome database / DNA compression / Sequence analysis |
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| 研究開始時の研究の概要 |
Biological and medical research uses huge databases of genome sequences. Currently all such databases use outdated compression technology. The NAF compression format that we invented recently allows to making databases more compact and much faster to access. This project focuses on developing infrastructure that will allow the field to transition to the NAF format. Such infrastructure includes reference genome database in NAF format, and software tools supporting this format. This project will improve efficiency of biological and medical research, contributing to science and public health.
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| 研究成果の概要 |
Short version, see English version for details. Achievements of this project: (1) Advancing the Nucleotide Archival Format. (2) Sequence Compression Benchmark. (3) Using NAF for the GenomeSync database. (4) Supporting NAF in bioinformatic tools. (5) Publishing 9 papers related to this project.
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| 研究成果の学術的意義や社会的意義 |
Genome data is increasingly used across many fields of science. NAF greatly increases efficiency of working with such data compared to previous formats. This project applied, improved and advanced NAF towards becoming the fundamental infrastructure tool for the next generation of genome databases.
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