長期的葉酸摂取の把握を通じたダウン症候群リスク低減に向けた分子疫学研究

• 研究課題/領域番号: 21590699
• 研究種目: 基盤研究(C)
• 配分区分: 補助金
• 応募区分: 一般
• 研究分野: 公衆衛生学・健康科学
• 研究機関: 長崎大学
• 研究代表者: 高村 昇 長崎大学, 医歯薬学総合研究科, 准教授 (30295068)
• 研究分担者: 増崎 英明 長崎大学, 医歯薬学総合研究科, 教授 (00173740) ; 大石 和代 長崎大学, 医歯薬学総合研究科, 教授 (00194069) ; 林田 直美 長崎大学, 医歯薬学総合研究科, 助教 (00420638) ; 和田 光弘 長崎大学, 大学院・医歯薬学総合研究科, 准教授 (40295093)
• 研究期間 (年度): 2009 – 2011
• 研究課題ステータス: 完了 (2011年度)
• 配分額: 4,550千円 (直接経費: 3,500千円、間接経費: 1,050千円); 2011年度: 1,300千円 (直接経費: 1,000千円、間接経費: 300千円); 2010年度: 1,560千円 (直接経費: 1,200千円、間接経費: 360千円); 2009年度: 1,690千円 (直接経費: 1,300千円、間接経費: 390千円)
• キーワード: 母子保健 / ダウン症候群 / 葉酸

研究概要

各世代における遺伝子多型とホモシステインの関連をみるために、新生児、母親、さらに祖母の三世代におけるサンプリングを行った。サンプリングはすべての世代で終了しており、世代によってホモシステイン・葉酸代謝とMTHFR遺伝子多型との関連が異なることを示した。

研究成果

• [雑誌論文] Lessons from Chernobyl (2011)
  • 著者名/発表者名: Takamura N, Yamashita S
  • 雑誌名: Fukushima J Med Sci 巻: 57(2) ページ: 81-5
  • NAID: 130002153588
• [雑誌論文] Cardiorespiratory fitness and metabolic markers in healthy young adult men (2011)
  • 著者名/発表者名: Yagura C, Takamura N, Goto Y, Sugihara H, Sota T, Oka S, Shimoda T, Yoshizumi K
  • 雑誌名: J Phys Ther Sci 巻: 23(6) ページ: 845-9
  • NAID: 10030481931
• [雑誌論文] Factors associated with radiographic osteoarthritis of the knee among community-dwelling Japanese women : the Hizen-Oshima Study (2011)
  • 著者名/発表者名: Vasilkova O, Mikhort T, Sanec I, Sharshakova T, Hayashida N, Takamura N. Aoyagi K
  • 雑誌名: J Orthop Sci 巻: 16(1) ページ: 51-5
  • NAID: 10029572611
• [雑誌論文] Longitudinal study to identify factors predicting health-related quality of life in knee osteoarthritis among community-dwelling women in Japan : The Hizen-Oshima Study (2011)
  • 著者名/発表者名: Norimatsu T, Osaki M, Tomita M, Ye Z, Abe Y, Honda S, Kanagae M, Mizukami S, Takamura N, Kusano Y, Shindo H, Aoyagi K
  • 雑誌名: Orthopedics 巻: 34(9)
• [雑誌論文] Screening for 137Cs Body Burden due to the Chernobyl Accident in Korosten City, Zhitomir, Ukraine : 1996-2008 (2011)
  • 著者名/発表者名: Hayashida N, Sekitani Y, Kozlovsky A, Rafalsky R, Gutevich O, Daniliuk V, Yamashita S, Takamura N
  • 雑誌名: J Rad Res 巻: 52(5) ページ: 629-3
  • NAID: 10029455999
• [雑誌論文] Background radiation and individual dosimetry in the costal area of Tamil Nadu, India (2011)
  • 著者名/発表者名: Matsuda N, Brahmanandhan GM, Yoshida M, Takamura N, Suyama A, Koguchi Y, Juto N, Raj YL, Winsley G, Selvasekarapandian S
  • 雑誌名: Radiat Prot Dosimetry 巻: 146(1-3) ページ: 314-7
  • NAID: 120006985027
• [雑誌論文] Relation of body mass index to blood folate and total homocysteine concentrations in Japanese adults (2011)
  • 著者名/発表者名: Nakazato M, Maeda T, Takamura N, Wada M, Yamasaki H, Johnston KE, Tamura T
  • 雑誌名: Eur J Nut 巻: 50(7) ページ: 581-5
  • NAID: 120006984813
• [雑誌論文] Suitability of tartrate-resistant Acid phosphatase type 5b as a screening marker for bone mineral density in community-dwelling elderly individuals (2011)
  • 著者名/発表者名: Irie S, Hayashida N, Shinkawa T, Taira Y, Sekitani Y, Teraoka S, Hashiguchi K, Yoshida K, Morishita M, Takamura N
  • 雑誌名: Tohoku J Exp Med 巻: 224(2) ページ: 105-10
  • NAID: 10028234060
• [雑誌論文] Mutational screening of the BRCA1 gene in sporadic breast cancer in the Kazakhstan population (2011)
  • 著者名/発表者名: Akilzhanova A, Meirmanov S, Zhunussova T, Nakashima M, Takamura N, Akanov Z, Masadykov A, Sandybaev M, Ramankulov E, Yamashita S, Sekine I
  • 雑誌名: Breast J 巻: 17(3) ページ: 328-30
• [雑誌論文] Prevalence of antithyroid antibodies and thyroid-stimulating hormone concentration in young people (2011)
  • 著者名/発表者名: Sekitani Y, Hayashida N, Karevskaya IV, Zubareva IA, Kozlovsky A, Yamashita S, Takamura N
  • 雑誌名: Clin Chem Lab Med 巻: 49(4) ページ: 747-9
  • NAID: 120006985125
• [雑誌論文] Quantitative ultrasound and radiographic absorptiometry are associated with vertebral deformity in Japanese women : the Hizen-Oshima Study (2011)
  • 著者名/発表者名: Abe Y, Takamura N, Ye Z, Tomita M, Osaki M, Kusano Y, Nakamura T, Aoyagi K, Honda S
  • 雑誌名: Osteoporosis Int 巻: 22(4) ページ: 1167-73
• [雑誌論文] A proposed method for the evaluation of body fat in Japanese adults that predicts obesity (2011)
  • 著者名/発表者名: Minematsu K, Takamura N, Goto K, Honda S, Aoyagi K, Moji K, Tsunawake N
  • 雑誌名: Nutr Res 巻: 31(2) ページ: 113-21
• [雑誌論文] The association between atherosclerosis and plasma homocysteine concentration in the general population residing on remote islands in Japan (2011)
  • 著者名/発表者名: Nakazato M, Takamura N, Kadota K, Yamasaki H, Mukae H, Kusano Y, Nakashima K, Ozono Y, Aoyagi K, Kohno S, Maeda T
  • 雑誌名: Acta Med Nagasaki 巻: 55(1) ページ: 47-54
• [雑誌論文] Aoyagi K. Factors associated with radiographic osteoarthritis of the knee among community-dwelling Japanese women : the Hizen-Oshima Study (2011)
  • 著者名/発表者名: Hashikawa K, Osaki M, Ye Z, Tomita M, Abe Y, Honda S, Takamura N, Shindo H
  • 雑誌名: J Orthop Sci 巻: 16(1) ページ: 51-5
• [雑誌論文] Testosterone is an independent determinant of bone mineral density in men with type 2 diabetes mellitus (2011)
  • 著者名/発表者名: Vasilkova O, Mikhort T, Sanec I, Sharshakova T, Hayashida N, Takamura N
  • 雑誌名: Clin Chem Lab Med 巻: 49(1) ページ: 99-103
  • NAID: 120006985156
• [雑誌論文] Current concentration of artificial radionuclides and estimated radiation doses around the Chernobyl Nuclear Power Plant, the Semipalatinsk Nuclear Testing Site, and in Nagasaki (2011)
  • 著者名/発表者名: Taira Y, Hayashida N, Brahmanandhan GM, Nagayama Y, Yamashita S, Takahashi J, Gutevitc A, Kozlovsky A, Urazalin M, Takamura N
  • 雑誌名: J Rad Res 巻: 52(1) ページ: 88-95
• [雑誌論文] Urinary iodine concentrations in the high background radiation areas of Kanyakumari district, Tamilnadu, India (2011)
  • 著者名/発表者名: Brahmanandhan GM, Hayashida N, Taira Y, Malathi J, Khnna D, Selvasekarapandian U, Matsuda N, Takamura N
  • 雑誌名: Endocr J 巻: 57(1) ページ: 87-91
  • NAID: 10029583495
• [雑誌論文] Quantitative ultrasound and radiographic absorptiometry are associated with vertebral deformity in Japanese women : the Hizen-Oshima Study (2011)
  • 著者名/発表者名: Abe Y, 等
  • 雑誌名: Osteoporosis Int 巻: 22 ページ: 1167-1173
  • 査読あり
• [雑誌論文] Prevalence of antithyroid antibodies and thyroid-stimulating hormone concentration in young people (2011)
  • 著者名/発表者名: Sekitani Y, 等
  • 雑誌名: Clin Chem Lab Med 巻: 49 ページ: 747-749
  • 査読あり
• [雑誌論文] Mutational screening of the BRCA1 gene in sporadic breast cancer in the Kazakhstan population (2011)
  • 著者名/発表者名: Akilzhanova A, 等
  • 雑誌名: Breast J 巻: 17 ページ: 328-330
  • 査読あり
• [雑誌論文] Suitability of tartrate-resistant Acid phosphatase type 5b as a screening marker for bone mineral density in community-dwelling elderly individuals (2011)
  • 著者名/発表者名: Irie S, 等
  • 雑誌名: Tohoku J Exp Med 巻: 224 ページ: 105-110
  • 査読あり
• [雑誌論文] Relation of body mass index to blood folate and total homocysteine concentrations in Japanese adults (2011)
  • 著者名/発表者名: Nakazato M, 等
  • 雑誌名: Eur J Nutr 巻: 50 ページ: 581-585
  • 査読あり
• [雑誌論文] Background radiation and individual dosimetry in the costal area of Tamil Nadu, India (2011)
  • 著者名/発表者名: Matsuda N, 等
  • 雑誌名: Radiation Prot Dosimetry 巻: 146 ページ: 314-317
  • 査読あり
• [雑誌論文] Screening for 137Cs Body Burden due to the Chernobyl Accident in Korosten City, Zhitomir, Ukraine : 1996-2008 (2011)
  • 著者名/発表者名: Hayashida N, 等
  • 雑誌名: J Rad Res 巻: 52 ページ: 629-633
  • NAID: 10029455999
  • 査読あり
• [雑誌論文] Longitudinal study to identify factors predicting health-related quality of life in knee osteoarthritis among community-dwelling women in Japan : The Hizen-Oshima Study (2011)
  • 著者名/発表者名: Norimatsu T, 等
  • 雑誌名: Orthopedics 巻: 37
  • 査読あり
• [雑誌論文] Cardiorespiratory fitness and metabolic markers in healthy young adult men (2011)
  • 著者名/発表者名: Vasilkova O, 等
  • 雑誌名: J Phys Ther Sci 巻: 23 ページ: 845-849
  • 査読あり
• [雑誌論文] Lessons from Chernobyl (2011)
  • 著者名/発表者名: Takamura N, 等
  • 雑誌名: Fukushima J Med Sci 巻: 57 ページ: 81-85
  • NAID: 130002153588
  • 査読あり
• [雑誌論文] A proposed method for the evaluation of body fat in Japanese adults that predicts obesity. (2011)
  • 著者名/発表者名: Minematsu K, 他
  • 雑誌名: Nutr Res 巻: (印刷中 掲載確定)
  • 査読あり
• [雑誌論文] Leptin is an independent determinant of bone mineral density in men with type 2 diabetes mellitus. (2011)
  • 著者名/発表者名: Vasilkova O, 他
  • 雑誌名: Acta Diabetol 巻: (印刷中 掲載確定)
  • 査読あり
• [雑誌論文] Relation of body mass index to blood folate and total homocysteine concentrations in Japanese adults. (2011)
  • 著者名/発表者名: Nakazato M, 他
  • 雑誌名: Eur J Nutr 巻: (印刷中 掲載確定)
  • 査読あり
• [雑誌論文] Factors associated with radiographic osteoarthritis of the knee among community-dwelling Japanese women : the Hizen-Oshima Study. (2011)
  • 著者名/発表者名: Hashikawa K, 他
  • 雑誌名: J Orthop Sci 巻: (印刷中 掲載確定)
  • 査読あり
• [雑誌論文] Prevalence of antithyroid antibodies and thyroid-stimulating hormone concentration in young people. (2011)
  • 著者名/発表者名: Sekitani Y, 他
  • 雑誌名: Clin Chem Lab Med 巻: (印刷中 掲載確定)
  • 査読あり
• [雑誌論文] Quantitative ultrasound and radiographic absorptiometry are associated with vertebral deformity in Japanese women : the Hizen-Oshima Study. (2011)
  • 著者名/発表者名: Abe Y, 他
  • 雑誌名: Osteoporosis Int 巻: (印刷中 掲載確定)
  • 査読あり
• [雑誌論文] Mutational screening of the BRCA1 gene in sporadic breast cancer in the Kazakhstan population. (2011)
  • 著者名/発表者名: Akilzhanova A, 他
  • 雑誌名: Breast J 巻: (印刷中 掲載確定)
  • 査読あり
• [雑誌論文] Testosterone is an independent determinant of bone mineral density in men with type 2 diabetes mellitus. (2011)
  • 著者名/発表者名: Vasilkova O, 他
  • 雑誌名: Clin Chem Lab Med 巻: (印刷中 掲載確定)
  • 査読あり
• [雑誌論文] Current concentration of artificial radionuclides and estimated radiation doses around the Chernobyl Nuclear Power Plant, the Semipalatinsk Nuclear-Testing Site, and in Nagasaki. (2011)
  • 著者名/発表者名: Taira Y, 他
  • 雑誌名: J Rad Res 巻: 52 ページ: 88-95
  • 査読あり
• [雑誌論文] Subclinical hypothyroidism and the risk of coronary heart disease and mortality (2010)
  • 著者名/発表者名: Takamura N, Hayashida N, Maeda T
  • 雑誌名: JAMA 巻: 304(22) ページ: 2481-2
• [雑誌論文] Body mass index positively correlated with forced expiratory volume in 1 second/ forced vital capacity in population with relatively low prevalence of obesity (2010)
  • 著者名/発表者名: Fukahori S, Matsuse H, Takamura N, Tsuchida T, Kawano T, Fukushima C, Hideaki S, Kohno S
  • 雑誌名: Chin Med J 巻: 123(10) ページ: 2792-96
• [雑誌論文] Evaluation of 137Cs body burden in inhabitants of Bryansk Oblast, Russian Federation, where a high incidence of thyroid cancer was observed after the accident at the Chernobyl Nuclear Power Plant (2010)
  • 著者名/発表者名: Sekitani Y, Hayashida N, Karevskaya I, Vasiltsova O, Kozlovsky A, Omiya M, Yamashita S, Takamura N
  • 雑誌名: Radiat Prot Dosimetry 巻: 141(1) ページ: 36-42
• [雑誌論文] White blood cell count and cardiovascular biomarkers of atherosclerosis (2010)
  • 著者名/発表者名: Sekitani Y, Hayashida N, Kadota K, Yamasaki H, Abiru N, Nakazato M, Maeda T, Ozono Y, Takamura N
  • 雑誌名: Biomarkers 巻: 15(5) ページ: 454-60
  • NAID: 120006984914
• [雑誌論文] The FOXE1 locus is a major genetic determinant for radiation-related thyroid carcinoma in Chernobyl (2010)
  • 著者名/発表者名: Takahashi M, Saenko V, Rogounovitch TI, Kawaguchi T, Drozd VM, Takigawa-Imamura H, Akulevich NM, Ratanajaraya C, Mitsutake N, Takamura N, Danilova LI, Lushchik ML, Demidchik YE, Heath S, Yamada R, Lathrop M, Matsuda F, Yamashita S
  • 雑誌名: Hum Mol Genet 巻: 19(12) ページ: 2516-23
  • NAID: 120006984984
• [雑誌論文] Leptin : high molecular weight adiponectin ratio is independently correlated with carotid intima-media thickness in men, but not in women (2010)
  • 著者名/発表者名: Takamura N, Hayashida N, Hagane K, Kadota K, Yamasaki H, Abiru N, Ozono Y, Kamihira S, Ishibashi K, Nakazato M, Maeda T
  • 雑誌名: Biomarkers 巻: 15(4) ページ: 340-4
  • NAID: 120006984528
• [雑誌論文] Subclinical hypothyroidism and the risk of coronary heart disease and mortality. (2010)
  • 著者名/発表者名: Takamura N, 他
  • 雑誌名: JAMA 巻: 304 ページ: 2481-2
  • 査読あり
• [雑誌論文] Body mass index positively correlated with forced expiratory volume in 1 second / forced vital capacity in population with relatively low prevalence of obesity. (2010)
  • 著者名/発表者名: Fukahori S, 他
  • 雑誌名: Chin Med J 巻: 123 ページ: 2792-96
  • 査読あり
• [雑誌論文] Evaluation of ^<137>Cs body burden in inhabitants of Bryansk Oblast, Russian Federation, where a high incidence of thyroid cancer was observed after the accident at the Chernobyl Nuclear Power Plant. (2010)
  • 著者名/発表者名: Sekitani Y, 他
  • 雑誌名: Radiat Prot Dosimetry 巻: 141 ページ: 36-42
  • 査読あり
• [雑誌論文] White blood cell count and cardiovascular biomarkers of atherosclerosis. (2010)
  • 著者名/発表者名: Sekitani Y, 他
  • 雑誌名: Biomarkers 巻: 15 ページ: 454-60
  • 査読あり
• [雑誌論文] The FOXE1 locus is a major genetic determinant for radiation-related thyroid carcinoma in Chernobyl. (2010)
  • 著者名/発表者名: Takahashi M, 他
  • 雑誌名: Hum Mol Genet 巻: 19 ページ: 2516-23
  • 査読あり
• [雑誌論文] Leptin : high molecular weight adiponectin ratio is independently correlated with carotid intima-media thickness in men, but not in women. (2010)
  • 著者名/発表者名: Takamura N, 他
  • 雑誌名: Biomarkers 巻: 15 ページ: 340-4
  • NAID: 120006984528
  • 査読あり
• [雑誌論文] Urinary iodine concentrations in the high background radiation areas of Kanyakumari district, Tamilnadu, India. (2010)
  • 著者名/発表者名: Brahmanandhan GM, 他
  • 雑誌名: Endocr J 巻: 57 ページ: 87-91
  • 査読あり
• [雑誌論文] Leptin : high molecular weight adiponectin ratio is independently correlated with carotid intima-media thickness in men, but not in women. (2010)
  • 著者名/発表者名: Takamura N, 他
  • 雑誌名: Biomarkers (印刷中)
  • NAID: 120006984528
  • 査読あり
• [雑誌論文] Mutational screening of the BRCA1 gene in sporadic breast cancer in the Kazakhstan population. (2010)
  • 著者名/発表者名: Akilzhanova A, 他
  • 雑誌名: Breast J (印刷中)
  • 査読あり
• [雑誌論文] Urinary iodine concentrations in the high background radiation areas of Kanakumari district, Tamilnadu, India. (2010)
  • 著者名/発表者名: Brahmanandhan GM, 他
  • 雑誌名: Endocrine J 57 ページ: 87-91
  • 査読あり
• [雑誌論文] Percentage body fat assessed by bioelectrical impedance analysis as a new health index for rural areas in the Asia-Pacific region (2009)
  • 著者名/発表者名: Minematsu K, Kaneko Y, Nakazato M, Maeda T, Christopher NJ, Yoda T, Goto K, Takamura N, Mizota T
  • 雑誌名: Acta Med Nagasaki 巻: 54(1) ページ: 39-43
  • NAID: 110007463568
• [雑誌論文] Relationship between periodontal status and HbA1c in non-diabetics (2009)
  • 著者名/発表者名: Hayashida H, Kawasaki K, Yoshimura A, Kitamura M, Furugen R, Nakazato M, Takamura N, Hara Y, Maeda T, Saito T
  • 雑誌名: J Public Health Dent 巻: 69(3) ページ: 204-6
• [雑誌論文] Poor chewing ability is associated with lower mucosal moisture in elderly individuals (2009)
  • 著者名/発表者名: Shinkawa T, Hayashida N, Mori K, Washio K, Hashiguchi K, Taira Y, Morishita M, Takamura N
  • 雑誌名: Tohoku J Exp Med 巻: 219(4) ページ: 263-267
  • NAID: 10027082451
• [雑誌論文] A validated HPLC-fluorescence method with a semi-micro column for routine determination of homocysteine, cysteine and cysteamine, and the relation between the thiol derivatives in normal human plasma (2009)
  • 著者名/発表者名: Ichinose S, Nakamura M, Maeda M, Ikeda R, Wada M, Nakazato M, Ohba Y, Takamura N, Maeda T, Aoyagi K, Nakashima K
  • 雑誌名: Biomed Chromatogr 巻: 23(9) ページ: 935-9
• [雑誌論文] Depressive status on Chinese factory workers in Nagasaki, Japan (2009)
  • 著者名/発表者名: Date Y, Abe Y, Honda S, Ye Z, Takamura N, Tomita M, Osaki M, Aoyagi K
  • 雑誌名: Ind Health 巻: 47(4) ページ: 376-82
• [雑誌論文] Thyroid function is associated with carotid intima media thickness in euthyroid subjects (2009)
  • 著者名/発表者名: Takamura N, Akilzhanova A, Hayashida N, Kadota K, Yamasaki H, Usa T, Nakazato M, Maeda T, Ozono Y, Aoyagi K
  • 雑誌名: Atherosclerosis 巻: 204(2)
  • NAID: 120006981790
• [雑誌論文] Urinary iodine concentrations in urban and rural areas around Chernobyl Nuclear Power Plant (2009)
  • 著者名/発表者名: Taira Y, Hayashida N, Zhavaranak S, Kozlovsky A, Lyzikov A, Yamashita S, Takamura N
  • 雑誌名: Endocr J 巻: 56(2) ページ: 257-61
  • NAID: 10026913066
• [雑誌論文] Incidence of chronic obstructive pulmonary disease in general clinics and relevant factors with FEV1/ FVC (2009)
  • 著者名/発表者名: Fukahori S, Matsuse H, Takamura N, Hirose H, Tsuchida T, Kawano T, Fukushima C, Mizuta Y, Kohno S
  • 雑誌名: Int J Clin Prac 巻: 63(2) ページ: 269-74
• [雑誌論文] Estimation of blood loss in total knee arthroplasty with and without tourniquet (2009)
  • 著者名/発表者名: Nishiguchi M, Takamura N, Kono M, Aoyagi K
  • 雑誌名: Acta Med Nagasaki 巻: 53(4) ページ: 105-109
  • NAID: 110007031050
• [雑誌論文] Relationship between periodontal status and HbA_<1c> in non-diabetics. (2009)
  • 著者名/発表者名: Hayashida H, 他
  • 雑誌名: J Public Health Dent 69 ページ: 204-6
  • 査読あり
• [雑誌論文] Poor chewing ability is associated with lower mucosal moisture in elderly individuals. (2009)
  • 著者名/発表者名: Shinkawa T, 他
  • 雑誌名: J Public Health Dent 69 ページ: 204-6
  • 査読あり
• [雑誌論文] A validated HPLC-fluorescence method with a semi-micro column for routine determination of homocysteine, cysteine and cysteamine, and the relation between the thiol derivatives in normal human plasma. (2009)
  • 著者名/発表者名: Ichinose S, 他
  • 雑誌名: Biomed Chromatogr 47 ページ: 376-82
  • 査読あり
• [雑誌論文] Depressive status on Chinese factory workers in Nagasaki, Japan. (2009)
  • 著者名/発表者名: Date Y, 他
  • 雑誌名: Ind Health 23 ページ: 935-9
  • 査読あり
• [雑誌論文] Thyroid function is associated with carotid intima media thickness in euthyroid subjects. (2009)
  • 著者名/発表者名: Takamura N, 他
  • 雑誌名: Atherosclerosis 204
  • NAID: 120006981790
  • 査読あり
• [雑誌論文] Urinary iodine concentrations in urban and rural areas around Chernobyl Nuclear Power Plant. (2009)
  • 著者名/発表者名: Taira Y, 他
  • 雑誌名: Endocr J 56 ページ: 257-61
  • 査読あり
• [雑誌論文] Incidence of chronic obstructive pulmonary disease in general clinics and relevant factors with FEV1/FVC. (2009)
  • 著者名/発表者名: Fukahori S, 他
  • 雑誌名: Int J Clin Prac 63 ページ: 269-74
  • 査読あり
• [学会発表] Evaluation of Nutritional Status in Kazakhstan (2009)
  • 著者名/発表者名: Takamura N
  • 学会等名: V International Scientific Conference<ECOLOGY. RADIATION. HEALTH>
  • 発表場所: セミパラチンスク(カザフスタン共和国)
  • 年月日: 2009-08-29
• [図書] Oxford Textbook of Endocrinology and Diabetes (2011)
  • 著者名/発表者名: Nagataki S, Imaizumi M, Takamura N
  • 出版者: Disorders of iodine excess
• [図書] Oxford Textbook of Endocrinology and Diabetes (2011)
  • 著者名/発表者名: Nagataki S, 等
  • 出版者: Oxford
• [備考]
  • URL: http://www-sdc.med.nagasaki-u.ac.jp/radepi/index.html
• [備考]
  • URL: http://www-sdc.med.nagasaki-u.ac.jp/radepi/index.html
• [備考]
  • URL: http://www-sdc.med.nagasaki-u.ac.jp/radepi/index.html