| 配分額 *注記 |
4,680千円 (直接経費: 3,600千円、間接経費: 1,080千円)
2022年度: 1,430千円 (直接経費: 1,100千円、間接経費: 330千円)
2021年度: 3,250千円 (直接経費: 2,500千円、間接経費: 750千円)
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| 研究開始時の研究の概要 |
Membraneless droplets generated by liquid-liquid phase separation (LLPS) were likely protocells. However, their structures and functions are unclear. We propose to study assembly, structure, and function of membraneless protocell compartments such as polyester droplets and liquid crystal coacervates. By probing the ability of LLPS protocells to stably compartmentalize and protect biomolecules and connecting these to essential modern cellular functions, we hope to understand more about how primitive protocells and chemistries directly evolved into modern cells and biologies.
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