| 研究課題/領域番号 |
21K15609
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| 研究種目 |
若手研究
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| 配分区分 | 基金 |
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| 審査区分 |
小区分51010:基盤脳科学関連
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| 研究機関 | 京都大学 |
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研究代表者 |
Veale Richard 京都大学, 医学研究科, 助教 (80828880)
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| 研究期間 (年度) |
2021-04-01 – 2024-03-31
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| 研究課題ステータス |
交付 (2022年度)
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| 配分額 *注記 |
4,550千円 (直接経費: 3,500千円、間接経費: 1,050千円)
2023年度: 260千円 (直接経費: 200千円、間接経費: 60千円)
2022年度: 1,430千円 (直接経費: 1,100千円、間接経費: 330千円)
2021年度: 2,860千円 (直接経費: 2,200千円、間接経費: 660千円)
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| キーワード | Free Viewing / Superior Colliculus / Blindsight / Gaze Behavior / Saliency / Silicon Probe / Marmoset / Neural Prosthesis / Visual Attention / Neuroprosthesis |
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| 研究開始時の研究の概要 |
I will record brain activity in marmoset monkeys to understand how visual features like color or motion pull visual attention. The goal is to understand how the brain calculates which interesting thing to look at when there are many interesting things visible. This will help us build neural prosthetics that will directly stimulate the brain to repair deficits in attentional behavior caused by brain damage.
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| 研究実績の概要 |
This year, primary achievements were analysis of free viewing gaze data from control subjects and from human infants (a model with less top-down input), implementation of better predictive models for replacing missing visual cortex activity, and design and planning of the superior colliculus silicon probe implantations. Interestingly, infants past 12 months do not appear to have different looking patterns than marmosets, in contrast to our predictions (and thus using 12 month old infants as a null model against marmosets for comparison is tenable).
On the modeling side, I implemented foveation and gaze-centered versions of the target prediction (i.e. saliency map) models. This took longer than expected due to underestimation of their difficulty for real-time implementation. These are available freely on github.
Finally, to enable better throughput and administration of data, I implemented a pipeline to analyze gaze data and saliency (including saccade and other eye movement detections) which uses relational databases instead of the previous distributed file format, to save space and computation. I submitted a large review paper as well as several other original papers regarding the infant data as well as free viewing data from marmoset.
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| 現在までの達成度 (区分) |
現在までの達成度 (区分)
4: 遅れている
理由
Due to several factors influenced by COVID last year as well as unforeseen difficulties with some aspects of the modeling,, several aspects of the project (experiments) are running behind. Specifically, stimulation experiments in colliculus of marmoset and the marmoset blindsight surgeries are running behind.
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| 今後の研究の推進方策 |
I will begin recording and analysis (and possibly stimulation) of superior colliculus silicon probe data within the next month. Free viewing in marmosets is running behind due to constraints of space for experiments, but by collaborating with other teams using the same facility I should be able to complete the majority of the proposed research in some form.
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