日本版診断群分類(DPC)データベースを活用した臨床疫学研究

• 研究課題/領域番号: 22390131
• 研究種目: 基盤研究(B)
• 配分区分: 補助金
• 応募区分: 一般
• 研究分野: 公衆衛生学・健康科学
• 研究機関: 東京大学
• 研究代表者: 康永 秀生 東京大学, 医学部附属病院, 特任准教授 (90361485)
• 研究分担者: 堀口 裕正 東京大学, 医学部附属病院, 特任准教授 (50401104)
• 研究期間 (年度): 2010 – 2012
• 研究課題ステータス: 完了 (2012年度)
• 配分額: 19,630千円 (直接経費: 15,100千円、間接経費: 4,530千円); 2012年度: 6,110千円 (直接経費: 4,700千円、間接経費: 1,410千円); 2011年度: 6,110千円 (直接経費: 4,700千円、間接経費: 1,410千円); 2010年度: 7,410千円 (直接経費: 5,700千円、間接経費: 1,710千円)
• キーワード: 疫学 / 臨床疫学 / データベース / 診断群分類 / 日本版診断群分類 / 臨床疫学研究

研究概要

全国約1000施設から日本版診断群分類(DPC)データを収集し、東京大学にデータベースを構築し、データを用いた臨床疫学研究を実施した。外科手術の術後成績や施設症例数とアウトカムの関連、消化管手術後の偽膜性大腸炎発生のリスク、急性膵炎の重症度スコアによる在院死亡予測および薬剤の効果判定、化膿性脊椎炎の疫学、骨悪性腫瘍術後、大腿骨頚部骨折術後のアウトカムについて評価した。

研究成果

• [雑誌論文] Japanese Severity Score for Acute Pancreatitis Well Predicts In-hospital Mortality: A Nationwide Survey of 17,901 Cases (2013)
  • 著者名/発表者名: Hamada T, Yasunaga H, Nakai Y, IsayamaH, Horiguchi H, Fushimi K, Ohe K, KoikeK
  • 雑誌名: Journal of Gastroenterology
• [雑誌論文] Rarity of severe bleeding and perforation in endoscopic ultrasound-guided fine needle aspiration for submucosal tumors (2013)
  • 著者名/発表者名: Hamada T, Yasunaga H, Nakai Y, IsayamaH, Horiguchi H, Matsuda S, Fushimi K, Koike K.
  • 雑誌名: Digestive Diseases Science 巻: 58 号: 9 ページ: 2634-2638
  • DOI: 10.1007/s10620-013-2717-7
• [雑誌論文] Incidence and Risk Factors for Mortality of Vertebral Osteomyelitis: A Retrospective Analysis Using the Japanese Diagnosis Procedure Combination Database (2013)
  • 著者名/発表者名: Akiyama T, Chikuda H, Yasunaga H, Horiguchi H, Fushimi K, Saita K
  • 雑誌名: BMJ Open 巻: 3
• [雑誌論文] Incidence and risk factors for postoperative pulmonary embolism following primary musculoskeletal tumor surgery: Analysis of a national administrative database. (2013)
  • 著者名/発表者名: Ogura K, Yasunaga H, Horiguchi H, Ohe K, Shinoda Y, Tanaka S, Kawano H
  • 雑誌名: CORR 2013 巻: 471(10) 号: 10 ページ: 3310-3316
  • DOI: 10.1007/s11999-013-3073-9
  • 査読あり
• [雑誌論文] Does Mechanical Bowel Preparation Improve Quality of Laparoscopic Nephrectomy? Propensity Score-matched Analysis in Japanese Series (2013)
  • 著者名/発表者名: Sugihara T, Yasunaga H, Horiguchi H, Fujimura T, Nishimatsu H, Ohe K, Matsuda S, Fushimi K, Kattan MW, Homma Y
  • 雑誌名: Urology 巻: 81(1) ページ: 74-9
• [雑誌論文] A Nomogram Predicting Severe Adverse Events after Ureteroscopic Lithotripsy:12,372 Patients in Japanese NationalSeries (2013)
  • 著者名/発表者名: Sugihara T, Yasunaga H, Horiguchi H,Nishimatsu H, Kume H, Ohe K, Matsuda S, Fushimi K, Homma Y.
  • 雑誌名: BJU Int 巻: 111(3) ページ: 459-66
• [雑誌論文] A Nomogram Predicting Severe Adverse Events after Ureteroscopic Lithotripsy: 12,372 Patients in Japanese National Series. (2013)
  • 著者名/発表者名: Sugihara T, Yasunaga H, Horiguchi H, Nishimatsu H, Kume H, Ohe K, Matsuda S, Fushimi K, Homma Y.
  • 雑誌名: BJU Int. 巻: 111(3) ページ: 459-66
  • 査読あり
• [雑誌論文] A User-friendly Tool to Transform Large Scale Administrative Data into Wide Table Format using a MapReduce Program with a Pig Latin based Script. (2013)
  • 著者名/発表者名: Horiguchi H, Yasunaga H, Hashimoto H, Ohe K. .
  • 雑誌名: BMC Medical Informatics and Decision Making 巻: 12 ページ: 151-151
  • 査読あり
• [雑誌論文] Does Mechanical Bowel Preparation Improve Quality of Laparoscopic Nephrectomy? Propensity Score-matched Analysis in Japanese Series. (2013)
  • 著者名/発表者名: Sugihara T, Yasunaga H, Horiguchi H, Fujimura T, Nishimatsu H, Ohe K, Matsuda S, Fushimi K, Kattan MW, Homma Y.
  • 雑誌名: Urology 巻: 81(1) ページ: 74-9
  • 査読あり
• [雑誌論文] Relationship between hospital volume and operative mortality for liver resection: data from the Japanese Diagnosis Procedure Combination database (2012)
  • 著者名/発表者名: Yasunaga H, Horiguchi H, Matsuda S, Fushimi K, Hashimoto H, Ohe K, Kokudo N
  • 雑誌名: Hepatol Res 巻: 42(11) ページ: 1073-1080
• [雑誌論文] The Burden of Clostridium difficile-Associated Disease following Digestive Tract Surgery in Japan (2012)
  • 著者名/発表者名: Yasunaga H, Horiguchi H, Hashimoto H, Matsuda S, Fushimi K
  • 雑誌名: J Hosp Infect 巻: 82(3) ページ: 175-80
• [雑誌論文] Effect and Cost of Treatment for Acute Pancreatitis With or Without Gabexate Mesylate: A Propensity Score Analysis Using a Nationwide Administrative Database (2012)
  • 著者名/発表者名: Yasunaga H, Horiguchi H, Hashimoto H, Matsuda S, Fushimi K
  • 雑誌名: Pancreas
• [雑誌論文] Risk factors affecting in-hospital mortality after hip fracture: retrospective analysis using the Japanese Diagnosis Procedure Combination database (2012)
  • 著者名/発表者名: Shoda N, Yasunaga H, Horiguchi H, Kadono Y, Matsuda S, Tanaka S
  • 雑誌名: BMJ Open 巻: 2(3)
• [雑誌論文] Renal haemorrhage risk after extracorporeal shockwave lithotripsy: results from the Japanese Diagnosis Procedure Combination Database (2012)
  • 著者名/発表者名: Sugihara T, Yasunaga H, Horiguchi H, Nishimatsu H, Hirano Y, Matsuda S, Homma Y.
  • 雑誌名: BJU Int 巻: 110(8 Pt B)
• [雑誌論文] In-hospital outcomes and cost assessment between bipolar versus monopolar transurethral resection of the prostate (2012)
  • 著者名/発表者名: Sugihara T, Yasunaga H, Horiguchi H, Nakamura M, Nishimatsu H, Kume H, Ohe K, Matsuda S, Homma Y
  • 雑誌名: Journal of Endourology 巻: 26 ページ: 1053-8
• [雑誌論文] Regional, institutional and individual factors affecting selection of minimally invasive nephroureterectomy in Japan: A national database analysis (2012)
  • 著者名/発表者名: Sugihara T, Yasunaga H, Horiguchi H, Fujimura T, Nishimatsu H, Tsuru N, Kazuo S, Ohe K, Fushimi K, Homma Y
  • 雑誌名: Int J Urol 巻: 12 号: 7 ページ: 1-6
  • DOI: 10.1111/iju.12031
  • NAID: 10031190517
  • 査読あり
• [雑誌論文] Wide Range and Variations in Minimally Invasive Surgery For Renal Malignancy in Japan: A Population Based Analysis (2012)
  • 著者名/発表者名: Sugihara T, Yasunaga H, Horiguchi H, Tsuru N, Fujimura T, Nishimatsu H, Kume H, Ohe K, Matsuda S, Fushimi K, Homma Y
  • 雑誌名: International Journal of Clinical Oncology 巻: 18 号: 6 ページ: 1070-1077
  • DOI: 10.1007/s10147-012-0500-y
• [雑誌論文] A User-friendly Tool to Transform Large Scale Administrative Data into Wide Table Format using a MapReduce Program with a Pig Latin based Script (2012)
  • 著者名/発表者名: Horiguchi H, Yasunaga H, Hashimoto H, Ohe K
  • 雑誌名: BMC Medical Informaticsand Decision Making 巻: 12 ページ: 151-151
• [雑誌論文] Relationship between hospital volume and operative mortality for liver resection: data from the Japanese Diagnosis Procedure Combination database. (2012)
  • 著者名/発表者名: Yasunaga H, Horiguchi H, Matsuda S, Fushimi K, Hashimoto H, Ohe K, Kokudo N.
  • 雑誌名: Hepatol Res 巻: 42(11) ページ: 1073-1080
  • 査読あり
• [雑誌論文] Variation in cancer surgical outcomes associated with physician and nurse staffing: a retrospective observational study using the Japanese Diagnosis Procedure Combination Database. (2012)
  • 著者名/発表者名: Yasunaga H, Hashimoto H, Horiguchi H, Miyata H, Matsuda S
  • 雑誌名: BMC Health Serv Res 巻: 12 ページ: 129-129
  • 査読あり
• [雑誌論文] Impact of surgical intervention timing on Fournier’s gangrene case fatality: an analysis of 379 cases. (2012)
  • 著者名/発表者名: Sugihara T, Yasunaga H, Horiguchi H, Fujimura T, Ohe K, Matsuda S, Fushimi K, Homma Y.
  • 雑誌名: BJU Int. 巻: 110(11)
  • 査読あり
• [雑誌論文] The Burden of Clostridium difficile–Associated Disease following Digestive Tract Surgery in Japan. (2012)
  • 著者名/発表者名: Yasunaga H, Horiguchi H, Hashimoto H, Matsuda S, Fushimi K.
  • 雑誌名: J Hosp Infect. 巻: 82(3) ページ: 175-80
  • 査読あり
• [雑誌論文] Risk factors affecting in-hospital mortality after hip fracture: retrospective analysis using the Japanese Diagnosis Procedure Combination database. (2012)
  • 著者名/発表者名: Shoda N, Yasunaga H, Horiguchi H, Kadono Y, Matsuda S, Tanaka S.
  • 雑誌名: BMJ Open 巻: 2(3)
  • 査読あり
• [雑誌論文] In-hospital outcomes and cost assessment between bipolar versus monopolar transurethral resection of the prostate. (2012)
  • 著者名/発表者名: Sugihara T, Yasunaga H, Horiguchi H, Nakamura M, Nishimatsu H, Kume H, Ohe K, Matsuda S, Homma Y.
  • 雑誌名: Journal of Endourology 巻: 26 ページ: 1053-8
  • 査読あり
• [雑誌論文] Renal haemorrhage risk after extracorporeal shockwave lithotripsy: results from the Japanese Diagnosis Procedure Combination Database. (2012)
  • 著者名/発表者名: Sugihara T, Yasunaga H, Horiguchi H, Nishimatsu H, Hirano Y, Matsuda S, Homma Y.
  • 雑誌名: BJU Int. 巻: 110(8 Pt B)
  • 査読あり
• [雑誌論文] Relationship between hospital volume and operative mortality for liver resection : data from the Japanese Diagnosis Procedure Combination database (2012)
  • 著者名/発表者名: Hideo Yasunaga, Hiromasa Horiguchi, Shinya Matsuda, et al.
  • 雑誌名: Hepatology Research 巻: 42 号: 11 ページ: 1073-1080
  • DOI: 10.1111/j.1872-034x.2012.01022.x
  • 査読あり
• [雑誌論文] In-hospital outcomes and cost assessment between bipolar versus monopolar transurethral resection of the prostate (2012)
  • 著者名/発表者名: Toru Sugihara, Hideo Yasunaga, Hiromasa Horiguchi, et al.
  • 雑誌名: Journal of Endourology 巻: 26 号: 8 ページ: 1053-1058
  • DOI: 10.1089/end.2011.0592
  • 査読あり
• [雑誌論文] Management trends, angioembolization performance and multiorgan injury indicators of renal trauma from Japanese administrative claims data base (2012)
  • 著者名/発表者名: Toru Sugihara, Hideo Yasunaga, Hiromasa Horiguchi, et al.
  • 雑誌名: International Journal of Urology 巻: 19(6) 号: 6 ページ: 559-63
  • DOI: 10.1111/j.1442-2042.2012.02978.x
  • 査読あり